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1. 发明授权

US07044940B1 Storage container for a suspension used for medical purposes 失效
标题翻译：用于医疗用途的悬浮液的储存容器
公开(公告)号：US07044940B1
公开(公告)日：2006-05-16
申请号：US09547156
申请日：2000-04-11
申请人： Rainer Hahn , Uwe Grotz , Ulrich Prager
发明人： Rainer Hahn , Uwe Grotz , Ulrich Prager
IPC分类号： A61B7/00 , B65D83/10
CPC分类号： A61C5/66 , B65D2231/002
摘要： A storage container (1) for a suspension used for medical purposes, in particular for ultrasonically assisted treatment of periodontitis, dental cleaning or dental preparation, comprises a flexible pouch (2), the interior of which is accessible via a charging and discharging nozzle (5). Situated in the interior of the pouch (2) is a distance element (6), in which a groove system (8, 9, 10) is incorporated. The groove system communicates with the interior of the charging and discharging nozzle (5). When the pouch (2) of said storage container (1) is pressed flat during removal of the suspension it contains, the opposing sides (3, 4) of the pouch (3) are applied during the final phase of emptying against the distance element (6). The groove system (8, 9, 10) contained in the latter however remains clear and forms a path, via which even the last residues of the suspension may be reliably removed from the pouch (2).
摘要翻译：用于医疗用途，特别是用于牙周炎，牙齿清洁或牙科制剂的超声辅助治疗的悬液的储存容器（1）包括柔性袋（2），其内部可通过充放电喷嘴 5）。位于袋（2）的内部的是距离元件（6），其中结合有凹槽系统（8,9,10）。凹槽系统与充放电喷嘴（5）的内部连通。当所述储存容器（1）的袋（2）在其包含的悬浮液的移除期间被压平时，在排空距离元件的最后阶段期间施加袋（3）的相对侧面（3,4）（6）。然而，容纳在后者中的凹槽系统（8,9,10）保持透明并形成路径，甚至可以从袋（2）中可靠地移除悬架的最后残留物。

2. 发明授权

US06545390B1 Device for generating high-frequency mechanical vibrations for a dental handpiece 失效
标题翻译：用于为牙科手机产生高频机械振动的装置
公开(公告)号：US06545390B1
公开(公告)日：2003-04-08
申请号：US09547151
申请日：2000-04-11
申请人： Rainer Hahn , Uwe Grotz
发明人： Rainer Hahn , Uwe Grotz
IPC分类号： H02N206
CPC分类号： A61C17/20 , B06B1/0253 , B06B1/0611 , B06B2201/55 , B06B2201/76
摘要： A device for generating high-frequency mechanical vibrations for dental purposes comprises a current detector (50) fitted in the supply line of a vibration generator (12). The output signal of the current detector (50) is transmitted to one of the inputs of a control circuit (74), which at its other input receives a supply current nominal value signal. The output of the control circuit (74) is connected to the control terminal of a controllable oscillator (42), which together with a power stage (46 to 48) prepares the supply current for the vibration generator (12). In this manner, a constant output amplitude of the vibration generator is obtained independent of the load coupled to said vibration generator at any given time.
摘要翻译：用于产生用于牙科目的的高频机械振动的装置包括安装在振动发生器（12）的供应管线中的电流检测器（50）。电流检测器（50）的输出信号被发送到控制电路（74）的一个输入端，控制电路在其另一输入处接收电源电流标称值信号。控制电路（74）的输出连接到可控振荡器（42）的控制端子，可控振荡器（42）与功率级（46至48）一起为振动发生器（12）准备供电电流。以这种方式，独立于在任何给定时间耦合到所述振动发生器的负载，获得振动发生器的恒定输出振幅。

3. 发明授权

US06273717B1 Dental instrument for sonic or ultrasonic treatment 失效
标题翻译：用于声波或超声波治疗的牙科仪器
公开(公告)号：US06273717B1
公开(公告)日：2001-08-14
申请号：US09546922
申请日：2000-04-11
申请人： Rainer Hahn , Uwe Grotz
发明人： Rainer Hahn , Uwe Grotz
IPC分类号： A61C107
CPC分类号： A61C3/03
摘要： A dental instrument for sonic or ultrasonic treatment comprises a shank (1) to which a treatment section (2) is joined. The shank (1) and treatment section.(2) are made of matrix-bonded carbon fibers. The instrument can be machined out of a woven carbon fiber fabric or can be a compression molding or an injection molding. The mechanical properties of the instrument can be adjusted by varying the length of the carbon fibers.
摘要翻译：一种用于声波或超声处理的牙科器械包括一个与治疗部分（2）接合的柄部（1）。柄（1）和处理部分（2）由基质粘结的碳纤维制成。该仪器可以由编织碳纤维织物加工而成，或者可以是压塑或注模。可以通过改变碳纤维的长度来调节仪器的机械性能。

4. 发明申请

US20060093989A1 Dental therapeutic device 审中-公开
标题翻译：牙科治疗仪
公开(公告)号：US20060093989A1
公开(公告)日：2006-05-04
申请号：US10505473
申请日：2003-01-23
申请人： Rainer Hahn , Ulrich Prager
发明人： Rainer Hahn , Ulrich Prager
IPC分类号： A61C17/02
CPC分类号： A61C1/087 , A61C17/02 , A61M1/0064 , A61M1/0068 , A61M2210/0631 , A61M2210/0637
摘要： Disclosed is a dental therapeutic device used for infiltrating and/or rinsing tissue or hollow spaces bordered by tissue, particularly tooth tissue or hollow spaces bordered by tooth tissue, with a therapeutic fluid. The inventive device comprises a storage container (2) for the therapeutic fluid, a hollow needle (42) for feeding the therapeutic fluid into the tissue, a pump (15, 43, 47) feeding the therapeutic fluid from the storage container (2) to the hollow needle (42), and a pump (15, 43, 47) sucking therapeutic fluid from the tissue via the hollow needle (42). All of said components are comprised in a hand-piece-type unit, whereby a very compact dental therapeutic device is created which is easy to handle for the dentist and requires no external units or only units that are generally part of a dentist's practice.
摘要翻译：公开了一种牙科治疗装置，用于渗透和/或漂洗由组织，特别是由牙齿组织界定的牙齿组织或中空空间与治疗液体相邻的组织或中空空间。本发明的装置包括用于治疗流体的储存容器（2），用于将治疗流体输送到组织中的中空针（42），从贮存容器（2）供给治疗流体的泵（15,43,47）以及从所述组织经由所述中空针（42）吸取治疗性流体的泵（15,43,47）。所有这些组件均包括在手持式单元中，由此创建了非常紧凑的牙科治疗装置，其易于处理牙医，并且不需要外部单元，或不需要通常是牙医实践的一部分的单元。

5. 发明授权

US07163397B2 Apparatus for applying material for selectively modifying the optical properties of metabolically different cells 失效
标题翻译：用于施加材料以选择性地改变代谢不同细胞的光学性质的装置
公开(公告)号：US07163397B2
公开(公告)日：2007-01-16
申请号：US10753799
申请日：2004-01-08
申请人： Rainer Hahn , Klaus Irion
发明人： Rainer Hahn , Klaus Irion
IPC分类号： A61C5/00 , A61C5/04
CPC分类号： A61K49/0036 , A61B5/0088 , A61C19/063 , A61K6/10 , A61K41/0057 , A61K49/0021 , A61K49/0073 , C08L91/00
摘要： An apparatus for applying a viscous modification material includes a material source of the modification material and a needle connected to the source. A material for selectively modifying the optical properties of cells comprises a basic material and a modification substance distributed in the basic material at a prescribed concentration, wherein the basic material comprises a viscous fluid, a gel, a two-dimensional or three-dimensional porous substrate or a material which hardens in situ. A diagnostic apparatus for determining the optical properties of cells which have been exposed to such a material and an apparatus for irradiating cells whose optical properties have been differently modified with such a material are also provided.
摘要翻译：用于施加粘性改性材料的装置包括改性材料的材料源和连接到源的针。用于选择性地改变电池的光学性质的材料包括以规定浓度分布在碱性材料中的碱性材料和改性物质，其中基本材料包括粘性流体，凝胶，二维或三维多孔基材或原位硬化的材料。还提供了一种用于确定暴露于这种材料的电池的光学特性的诊断装置和用于照射具有这种材料的光学性能被不同地修改的电池的装置。

6. 发明授权

US06997883B1 Diagnostic apparatus for determining the remineralization ability of tissue 失效
标题翻译：用于确定组织再矿化能力的诊断装置
公开(公告)号：US06997883B1
公开(公告)日：2006-02-14
申请号：US09402731
申请日：1998-04-07
申请人： Rainer Hahn
发明人： Rainer Hahn
IPC分类号： A61B5/00 , A61C19/04
CPC分类号： A61C19/04 , A61B5/0059 , A61B5/05 , A61B5/4547 , A61B8/08 , A61C3/03
摘要： The invention relates to a diagnostic apparatus with which diseased hard tissue, in particular carious dental tissue, can be examined through a small working channel, to see whether it can be made healthy again by remineralization. This diagnosis apparatus tightly (54) seals the working channel, produced in the tissue, from its environment, and places the cavity in the tissue under pressure, after which the pressurization is ended and a pressure drop is measured by means of a pressure measuring instrument (60). The speed of the drop in pressure is a measure of the extent of the changes to the diseased tissue. The invention also relates to a treatment device for supporting the remineralization or reinfiltration of diseased hard tissue and for preparing this, as well as to diagnosis and treatment agents and treatment substances.
摘要翻译：本发明涉及通过小工作通道检查病变硬组织，特别是龋牙组织的诊断装置，以便通过再矿化观察其是否可再次健康。该诊断装置（54）紧密地密封在组织中产生的工作通道与其环境，并将空腔置于组织中的压力下，之后加压结束，并通过压力测量仪器测量压降（60）。压力下降的速度是对病变组织变化程度的度量。本发明还涉及一种用于支持患病硬组织的再矿化或再渗透并用于制备其的治疗装置，以及诊断和治疗剂和治疗物质。

7. 发明授权

US09248319B2 Composite particles for use in oral hygiene 有权
标题翻译：复合颗粒用于口腔卫生
公开(公告)号：US09248319B2
公开(公告)日：2016-02-02
申请号：US12851623
申请日：2010-08-06
申请人： Wojciech Pisula , Stephanie Schäffer , Juri Tschernjaew , Arnold Storeck , Rainer Hahn
发明人： Wojciech Pisula , Stephanie Schäffer , Juri Tschernjaew , Arnold Storeck , Rainer Hahn
IPC分类号： A61K8/00 , A61Q11/00 , A61K8/02 , A61K8/25 , A61K8/27 , A61K8/34 , A61K8/73
CPC分类号： A61Q11/00 , A61K8/0279 , A61K8/25 , A61K8/27 , A61K8/347 , A61K8/733 , A61K2800/28 , A61K2800/412 , A61K2800/56
摘要： The present invention relates to functional composite particles for the oral care sector, more particularly for toothpastes and mouthwashes, which are charged with active ingredients which ensure a long-term antimicrobial or antibacterial effect in the oral cavity and hence reduce the formation of plaque and halitosis. The invention further relates to a process for producing these composite particles and also to their use for producing oral hygiene articles.
摘要翻译：本发明涉及用于口腔护理部门的功能性复合颗粒，更具体地说是用于牙膏和漱口水，其中装有活性成分，其确保在口腔中长期的抗微生物或抗菌作用，从而减少斑块和口臭的形成。本发明还涉及一种生产这些复合颗粒的方法以及它们用于生产口腔卫生制品的方法。

8. 发明申请

US20110033511A1 COMPOSITE PARTICLES FOR USE IN ORAL HYGIENE 有权
标题翻译：用于口腔卫生的复合颗粒
公开(公告)号：US20110033511A1
公开(公告)日：2011-02-10
申请号：US12851623
申请日：2010-08-06
申请人： Wojciech Pisula , Stephanie Schäffer , Juri Tschernjaew , Arnold Storeck , Rainer Hahn
发明人： Wojciech Pisula , Stephanie Schäffer , Juri Tschernjaew , Arnold Storeck , Rainer Hahn
IPC分类号： A61K8/02 , A61Q11/00
CPC分类号： A61Q11/00 , A61K8/0279 , A61K8/25 , A61K8/27 , A61K8/347 , A61K8/733 , A61K2800/28 , A61K2800/412 , A61K2800/56
摘要： The present invention relates to functional composite particles for the oral care sector, more particularly for toothpastes and mouthwashes, which are charged with active ingredients which ensure a long-term antimicrobial or antibacterial effect in the oral cavity and hence reduce the formation of plaque and halitosis. The invention further relates to a process for producing these composite particles and also to their use for producing oral hygiene articles.
摘要翻译：本发明涉及用于口腔护理部门的功能性复合颗粒，更具体地说是用于牙膏和漱口水，其中装有活性成分，其确保在口腔中长期的抗微生物或抗菌作用，从而减少斑块和口臭的形成。本发明还涉及一种生产这些复合颗粒的方法以及它们用于生产口腔卫生制品的方法。

9. 发明申请

US20090203069A1 Organic compounds 有权
标题翻译：有机化合物
公开(公告)号：US20090203069A1
公开(公告)日：2009-08-13
申请号：US11919257
申请日：2006-04-25
申请人： Alois Jungbauer , Rainer Hahn , Anne Tscheliessnig , Waltraud Kaar
发明人： Alois Jungbauer , Rainer Hahn , Anne Tscheliessnig , Waltraud Kaar
IPC分类号： C12P21/06 , C07K7/06 , C07K7/08
CPC分类号： C12P21/02 , C07K1/22 , C07K17/06 , C12N9/506 , C12N15/62
摘要： Disclosed is a method for the production of a heterologous polypeptide of interest with a homogenous N-terminus, using a fusion polypeptide comprising the polypeptide of interest and N-terminally thereto a polypeptide exhibiting autoproteolytic function, said method comprising the steps of a) binding of the fusion polypeptide in a soluble, autoproteolytically inactive form by an affinity chromatography system, b) refolding of the fusion polypeptide, thereby activating the autoproteolytic function of the fusion polypeptide and causing cleavage of the heterologous polypeptide of interest, and c) subsequently eluting the heterologous polypeptide of interest, wherein said steps are conducted on one affinity chromatography system.
摘要翻译：公开了使用包含感兴趣的多肽的融合多肽和N末端具有表达自身蛋白水解功能的多肽来产生具有均质N末端的异源多肽的方法，所述方法包括以下步骤：a）通过亲和层析系统以可溶性，自动蛋白水解无活性形式的融合多肽，b）融合多肽的折叠，从而激活融合多肽的自体蛋白水解功能，并导致感兴趣的异源多肽切割，以及c）随后将异源多肽，其中所述步骤在一个亲和层析系统上进行。

10. 发明授权

US06310259B1 Method for producing 6,10 and 6,9-dimethyl-5,10-undecadienyl-2-ones 失效
标题翻译：制备6,10和6,9-二甲基-5,10-十一二烯基-2-酮的方法
公开(公告)号：US06310259B1
公开(公告)日：2001-10-30
申请号：US09446734
申请日：2000-03-23
申请人： Wilhelm Keim , Armin Kraus , Rainer Hahn , Klaus Huthmacher
发明人： Wilhelm Keim , Armin Kraus , Rainer Hahn , Klaus Huthmacher
IPC分类号： C07C4500
CPC分类号： C07C45/676 , C07C49/203 , C07C67/347 , C07C69/738
摘要： The present application refers to a process for preparing 6,10- and 6,9-dimethyl-5,10-undecadienyl-2-ones by telomerizing isoprene with alkyl acetoacetates in the presence of a catalyst system containing a transition metal compound catalyst and a phosphorus- or arsenic-containing compound cocatalyst, wherein the process is performed in the presence of a protic additive of the general formula in which: R1, R2, R3 represent an alkyl group with 1 to 9 carbon atoms, branched or unbranched, a cycloalkyl group with 6 to 8 carbon atoms, an aryl group, in particular phenyl, or an arylalkyl group, X(−) represents an inorganic or organic anion, y is 1 or 2, and the &bgr;-ketoester so obtained is saponified and decarboxylated in a manner known per se.
摘要翻译：本申请是指通过在含有过渡金属化合物催化剂的催化剂体系存在下将异戊二烯与乙酰乙酸烷基酯聚合来制备6,10-和6,9-二甲基-5,10-十一二烯基-2-酮的方法，含磷或砷的化合物助催化剂，其中该方法在一般形式的质子添加剂存在下进行：其中R1，R2，R3代表具有1至9个碳原子的烷基，支链或非支链，环烷基具有6至8个碳原子，芳基，特别是苯基或芳基烷基，X（ - ）表示无机或有机阴离子，y为1或2，所得到的β-酮酯被皂化并脱羧本身已知的方式。

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