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1. 发明申请

US20120107245A1 DENTAL COMPOSITION FOR DETECTION OF CARIOUS TISSUE, DETECTION METHOD 审中-公开
标题翻译：用于检测重症组织的牙齿组合物，检测方法
公开(公告)号：US20120107245A1
公开(公告)日：2012-05-03
申请号：US13348310
申请日：2012-01-11
申请人： Rainer Guggenberger , Thomas Luchterhandt , Ingo R. Haeberlein , Oliver Kappler , Miriam Hansen
发明人： Rainer Guggenberger , Thomas Luchterhandt , Ingo R. Haeberlein , Oliver Kappler , Miriam Hansen
IPC分类号： A61K49/00 , A61P1/02
CPC分类号： A61Q11/00 , A61K8/24 , A61K8/466 , A61K8/49 , A61K49/006 , A61K49/0071 , A61K2800/45
摘要： A dental composition and method for detecting carious tissue on the surface of a tooth, and the use of the dental composition to manufacture a remedy for detection of carious tissue. The dental composition can comprise an aqueous solution of 1) at least one acidic compound, 2) at least one salt of said acidic compound, 3) at least one indicator that generates a detectable signal when said solution reaches a particular pH value that is less than 5.5; wherein 1) and 2) are selected such that the aqueous solution has a pH of less than that particular pH value where the indicator generates the signal. The method can comprise the steps of 1) providing the above mentioned dental composition, 2) applying said composition to the surface of said tooth, and 3) measuring the amount of time required for the composition to change color.
摘要翻译：用于检测牙齿表面上的龋齿组织的牙科用组合物和方法，以及牙科组合物用于制造用于检测龋齿组织的补救剂的用途。牙科用组合物可以包含1）至少一种酸性化合物的水溶液，2）所述酸性化合物的至少一种盐，3）当所述溶液达到特定pH值较小时产生可检测信号的至少一种指示剂超过5.5; 其中选择1）和2）使得水溶液的pH值小于指示剂产生信号的特定pH值。该方法可以包括以下步骤：1）提供上述牙齿组合物，2）将所述组合物施用到所述牙齿的表面，以及3）测量所述组合物改变颜色所需的时间量。

2. 发明申请

US20080241800A1 Dental Composition For Detection of Carious Tissue, Detection Method 审中-公开
标题翻译：用于检测龋齿组织的牙科组合，检测方法
公开(公告)号：US20080241800A1
公开(公告)日：2008-10-02
申请号：US11914990
申请日：2006-05-24
申请人： Rainer Guggenberger , Thomas Luchterhandt , Ingo R. Haeberlein , Miriam Hansen
发明人： Rainer Guggenberger , Thomas Luchterhandt , Ingo R. Haeberlein , Miriam Hansen
IPC分类号： C09K3/00 , A61K6/00
CPC分类号： A61Q11/00 , A61K8/24 , A61K8/466 , A61K8/49 , A61K49/006 , A61K49/0071 , A61K2800/45
摘要： The present invention relates to a dental composition comprising an aqueous solution of 1) at least one acidic compound, 2) at least one salt of said acidic compound, 3) at least one indicator that generates a detectable signal when said solution reaches a particular pH value that is less than 5.5 wherein 1) and 2) are selected such that the aqueous solution has a pH of less than that particular pH value where the indicator generates the signal. It further relates to a method for detection of carious tissue on the surface of a tooth, comprising the steps of 1) providing the above mentioned dental composition, 2) applying said composition to the surface of said tooth, and 3) measuring the amount of time required for the composition to change color.It further relates to the use of said dental composition to manufacture a remedy for detection of carious tissue.
摘要翻译：本发明涉及一种牙科用组合物，其包含1）至少一种酸性化合物的水溶液，2）所述酸性化合物的至少一种盐，3）当所述溶液达到特定pH时产生可检测信号的至少一种指示剂选择小于5.5的值，其中1）和2）被选择为使得水溶液的pH值小于指示剂产生信号的特定pH值。它还涉及一种用于检测牙齿表面上的龋齿组织的方法，包括以下步骤：1）提供上述牙科组合物，2）将所述组合物施用到所述牙齿的表面，以及3）组合物改变颜色所需的时间。它还涉及所述牙科用组合物的用途来制造用于检测龋齿组织的补救措施。

3. 发明授权

US07699605B2 Self-etching emulsion dental compositions and methods 有权
标题翻译：自腐蚀乳液牙科用组合物及方法
公开(公告)号：US07699605B2
公开(公告)日：2010-04-20
申请号：US12248338
申请日：2008-10-09
申请人： Steven M. Aasen , Ahmed S. Abuelyaman , David K. Cinader, Jr. , Hendrik M. Grupp , Miriam Hansen , Thomas Klettke , Guenther Lechner , Kevin M. Lewandowski , Thomas Luchterhandt , Sumita B. Mitra , Prabhakara S. Rao , Victoria A. Russell , Michael S. Wendland
发明人： Steven M. Aasen , Ahmed S. Abuelyaman , David K. Cinader, Jr. , Hendrik M. Grupp , Miriam Hansen , Thomas Klettke , Guenther Lechner , Kevin M. Lewandowski , Thomas Luchterhandt , Sumita B. Mitra , Prabhakara S. Rao , Victoria A. Russell , Michael S. Wendland
IPC分类号： A61C3/00 , A61K6/083
CPC分类号： A61K6/083 , A61K6/0023 , A61K49/14 , A61K49/221 , A61K49/227 , A61K51/08 , C08L33/04
摘要： The present invention is directed to dental compositions that can be used as adhesives for bonding a dental material to a dental structure surface and/or as a dental restorative material. The dental composition is preferably applied to a dental structure surface under conditions effective to etch the dental structure surface.
摘要翻译：本发明涉及可用作将牙科材料粘合到牙科结构表面和/或作为牙科修复材料的粘合剂的牙科用组合物。牙齿组合物优选在有效蚀刻牙科结构表面的条件下应用于牙科结构表面。

4. 发明申请

US20100036015A1 COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD 有权
标题翻译：组合物可以通过开环低温下的细胞分解聚合及其在牙齿领域中的应用而可固化
公开(公告)号：US20100036015A1
公开(公告)日：2010-02-11
申请号：US12517727
申请日：2007-12-18
申请人： Thomas Luchterhandt , Peter Bissinger , Miriam Hansen
发明人： Thomas Luchterhandt , Peter Bissinger , Miriam Hansen
IPC分类号： A61K6/093 , C08L83/00
CPC分类号： A61K6/093 , A61K6/083 , A61K6/10 , C08L65/00 , C08L83/00 , C08L25/00
摘要： The invention relates to a composition which is polymerizable by ring-opening metathesis polymerization (ROMP) comprising at least one monomer that is polymerizable by ROMP, at least one initiator of the Hoveyda-Grubbs type for initiating the ROMP and at least one retarder selected from the group consisting of heterocyclic a means having a ring with at least one N-atom and four or less other atoms constituting the ring bearing the at least one N-atom. The invention further relates to a process for the preparation of a composition which is polymerizable by ROMP, a dental material obtainable by polymerizing a composition according to the invention and the use of a substance selected from the group consisting of heterocyclic amines having a ring with at least one N-atom and five or less atoms constituting the ring bearing the at least one N-atom or of a mixture of two or more of such substances as a retarder in ROMP.
摘要翻译：本发明涉及通过开环易位聚合（ROMP）可聚合的组合物，其包含至少一种可通过ROMP聚合的单体，用于引发ROMP的至少一种Hoveyda-Grubbs型引发剂和至少一种选自由具有至少一个N原子和四个或更少的构成具有至少一个N原子的环的其它原子的环的杂环化合物组成的组。本发明还涉及一种制备可通过ROMP聚合的组合物的方法，可通过聚合根据本发明的组合物获得的牙科材料和使用选自以下的物质：具有环的杂环胺构成带有至少一个N-原子的环的至少一个N原子和五个或更少的原子，或者ROMP中的缓凝剂等两种或更多种物质的混合物。

5. 发明申请

US20050176844A1 Self-etching emulsion dental compositions and methods 有权
标题翻译：自腐蚀乳液牙科用组合物及方法
公开(公告)号：US20050176844A1
公开(公告)日：2005-08-11
申请号：US10916169
申请日：2004-08-11
申请人： Steven Aasen , Ahmed Abuelyaman , David Cinader , Hendrik Grupp , Miriam Hansen , Thomas Klettke , Guenther Lechner , Kevin Lewandowski , Thomas Luchterhandt , Sumita Mitra , Prabhakara Rao , Victoria Russell , Michael Wendland
发明人： Steven Aasen , Ahmed Abuelyaman , David Cinader , Hendrik Grupp , Miriam Hansen , Thomas Klettke , Guenther Lechner , Kevin Lewandowski , Thomas Luchterhandt , Sumita Mitra , Prabhakara Rao , Victoria Russell , Michael Wendland
IPC分类号： A61C3/00 , A61C5/00 , A61K6/00 , A61K6/083
CPC分类号： A61K6/083 , A61K6/0023 , A61K49/14 , A61K49/221 , A61K49/227 , A61K51/08 , C08L33/04
摘要： The present invention is directed to dental compositions that can be used as adhesives for bonding a dental material to a dental structure surface and/or as a dental restorative material. The dental composition is preferably applied to a dental structure surface under conditions effective to etch the dental structure surface.
摘要翻译：本发明涉及可用作将牙科材料粘合到牙科结构表面和/或作为牙科修复材料的粘合剂的牙科用组合物。牙齿组合物优选在有效蚀刻牙科结构表面的条件下应用于牙科结构表面。

6. 发明申请

US20090088494A1 SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION 有权
标题翻译：通过开环METATHESIS聚合获得的固体材料
公开(公告)号：US20090088494A1
公开(公告)日：2009-04-02
申请号：US12162429
申请日：2007-01-30
申请人： Thomas Luchterhandt , Peter Bissinger , Miriam Hansen
发明人： Thomas Luchterhandt , Peter Bissinger , Miriam Hansen
IPC分类号： A61K6/093 , C08L83/00
CPC分类号： A61K6/083 , C08G61/06 , C08L25/18
摘要： The invention describes solid materials, especially for dental purposes like, e.g., composite milling blocks (CMBs), which can be obtained by ring-opening metathesis polymerization (ROMP). Also described is a method for obtaining such milling blocks, their use and applications of the compositions.
摘要翻译：本发明描述了固体材料，特别是用于牙科用途，例如可通过开环易位聚合（ROMP）获得的复合研磨块（CMB）。还描述了获得这种研磨块的方法，它们在组合物中的应用和应用。

7. 发明申请

US20090035728A1 SELF-ETCHING EMULSION DENTAL COMPOSITIONS AND METHODS 有权
标题翻译：自我修复乳液牙齿组合物和方法
公开(公告)号：US20090035728A1
公开(公告)日：2009-02-05
申请号：US12248338
申请日：2008-10-09
申请人： Steven M. Aasen , Ahmed S. Abuelyaman , David K. Cinader, JR. , Hendrik M. Grupp , Miriam Hansen , Thomas Klettke , Guenther Lechner , Kevin M. Lewandowski , Thomas Luchterhandt , Sumita B. Mitra , Prabhakara S. Rao , Victoria A. Russell , Michael S. Wendland
发明人： Steven M. Aasen , Ahmed S. Abuelyaman , David K. Cinader, JR. , Hendrik M. Grupp , Miriam Hansen , Thomas Klettke , Guenther Lechner , Kevin M. Lewandowski , Thomas Luchterhandt , Sumita B. Mitra , Prabhakara S. Rao , Victoria A. Russell , Michael S. Wendland
IPC分类号： A61C5/04
CPC分类号： A61K6/083 , A61K6/0023 , A61K49/14 , A61K49/221 , A61K49/227 , A61K51/08 , C08L33/04
摘要： The present invention is directed to dental compositions that can be used as adhesives for bonding a dental material to a dental structure surface and/or as a dental restorative material. The dental composition is preferably applied to a dental structure surface under conditions effective to etch the dental structure surface.
摘要翻译：本发明涉及可用作将牙科材料粘合到牙科结构表面和/或作为牙科修复材料的粘合剂的牙科用组合物。牙齿组合物优选在有效蚀刻牙科结构表面的条件下应用于牙科结构表面。

8. 发明授权

US07452924B2 Self-etching emulsion dental compositions and methods 有权
标题翻译：自腐蚀乳液牙科用组合物及方法
公开(公告)号：US07452924B2
公开(公告)日：2008-11-18
申请号：US10916169
申请日：2004-08-11
申请人： Steven M. Aasen , Ahmed S. Abuelyaman , Hendrik M. Grupp , Miriam Hansen , Thomas Klettke , Guenther Lechner , Kevin M. Lewandowski , Thomas Luchterhandt , Sumita B. Mitra , Prabhakara S. Rao , Victoria A. Russell , Michael S. Wendland
发明人： Steven M. Aasen , Ahmed S. Abuelyaman , Hendrik M. Grupp , Miriam Hansen , Thomas Klettke , Guenther Lechner , Kevin M. Lewandowski , Thomas Luchterhandt , Sumita B. Mitra , Prabhakara S. Rao , Victoria A. Russell , Michael S. Wendland
IPC分类号： A61K6/083 , C08F2/32 , A61C5/00
CPC分类号： A61K6/083 , A61K6/0023 , A61K49/14 , A61K49/221 , A61K49/227 , A61K51/08 , C08L33/04
摘要： The present invention is directed to dental compositions that can be used as adhesives for bonding a dental material to a dental structure surface and/or as a dental restorative material. The dental composition is preferably applied to a dental structure surface under conditions effective to etch the dental structure surface.
摘要翻译：本发明涉及可用作将牙科材料粘合到牙科结构表面和/或作为牙科修复材料的粘合剂的牙科用组合物。牙齿组合物优选在有效蚀刻牙科结构表面的条件下应用于牙科结构表面。

9. 发明授权

US08431625B2 Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field 有权
标题翻译：通过低温下的开环易位聚合可固化的组合物及其在牙科领域中的应用
公开(公告)号：US08431625B2
公开(公告)日：2013-04-30
申请号：US12517727
申请日：2007-12-18
申请人： Thomas Luchterhandt , Peter Bissinger , Miriam Hansen
发明人： Thomas Luchterhandt , Peter Bissinger , Miriam Hansen
IPC分类号： A61K6/093
CPC分类号： A61K6/093 , A61K6/083 , A61K6/10 , C08L65/00 , C08L83/00 , C08L25/00
摘要： The invention relates to a composition which is polymerizable by ring-opening metathesis polymerization (ROMP) comprising at least one monomer that is polymerizable by ROMP, at least one initiator of the Hoveyda-Grubbs type for initiating the ROMP and at least one retarder selected from the group consisting of heterocyclic a means having a ring with at least one N-atom and four or less other atoms constituting the ring bearing the at least one N-atom. The invention further relates to a process for the preparation of a composition which is polymerizable by ROMP, a dental material obtainable by polymerizing a composition according to the invention and the use of a substance selected from the group consisting of heterocyclic amines having a ring with at least one N-atom and five or less atoms constituting the ring bearing the at least one N-atom or of a mixture of two or more of such substances as a retarder in ROMP.
摘要翻译：本发明涉及通过开环易位聚合（ROMP）可聚合的组合物，其包含至少一种可通过ROMP聚合的单体，用于引发ROMP的至少一种Hoveyda-Grubbs型引发剂和至少一种选自由具有至少一个N原子和四个或更少的构成具有至少一个N原子的环的其它原子的环的杂环化合物组成的组。本发明还涉及一种制备可通过ROMP聚合的组合物的方法，可通过聚合根据本发明的组合物获得的牙科材料和使用选自以下的物质：具有环的杂环胺构成带有至少一个N-原子的环的至少一个N原子和五个或更少的原子，或者ROMP中的缓凝剂等两种或更多种物质的混合物。

10. 发明授权

US08178604B2 Solid materials obtainable by ring-opening metathesis polymerization 有权
标题翻译：可通过开环易位聚合获得的固体材料
公开(公告)号：US08178604B2
公开(公告)日：2012-05-15
申请号：US12162429
申请日：2007-01-30
申请人： Thomas Luchterhandt , Peter Bissinger , Miriam Hansen
发明人： Thomas Luchterhandt , Peter Bissinger , Miriam Hansen
IPC分类号： C08J5/32
CPC分类号： A61K6/083 , C08G61/06 , C08L25/18
摘要： The invention describes solid materials, especially for dental purposes like, e.g., composite milling blocks (CMBs), which can be obtained by ring-opening metathesis polymerization (ROMP). Also described is a method for obtaining such milling blocks, their use and applications of the compositions.
摘要翻译：本发明描述了固体材料，特别是用于牙科用途，例如可通过开环易位聚合（ROMP）获得的复合研磨块（CMB）。还描述了获得这种研磨块的方法，它们在组合物中的应用和应用。

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