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    • 3. 发明授权
    • Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field
    • 通过低温下的开环易位聚合可固化的组合物及其在牙科领域中的应用
    • US08431625B2
    • 2013-04-30
    • US12517727
    • 2007-12-18
    • Thomas LuchterhandtPeter BissingerMiriam Hansen
    • Thomas LuchterhandtPeter BissingerMiriam Hansen
    • A61K6/093
    • A61K6/093A61K6/083A61K6/10C08L65/00C08L83/00C08L25/00
    • The invention relates to a composition which is polymerizable by ring-opening metathesis polymerization (ROMP) comprising at least one monomer that is polymerizable by ROMP, at least one initiator of the Hoveyda-Grubbs type for initiating the ROMP and at least one retarder selected from the group consisting of heterocyclic a means having a ring with at least one N-atom and four or less other atoms constituting the ring bearing the at least one N-atom. The invention further relates to a process for the preparation of a composition which is polymerizable by ROMP, a dental material obtainable by polymerizing a composition according to the invention and the use of a substance selected from the group consisting of heterocyclic amines having a ring with at least one N-atom and five or less atoms constituting the ring bearing the at least one N-atom or of a mixture of two or more of such substances as a retarder in ROMP.
    • 本发明涉及通过开环易位聚合(ROMP)可聚合的组合物,其包含至少一种可通过ROMP聚合的单体,用于引发ROMP的至少一种Hoveyda-Grubbs型引发剂和至少一种选自 由具有至少一个N原子和四个或更少的构成具有至少一个N原子的环的其它原子的环的杂环化合物组成的组。 本发明还涉及一种制备可通过ROMP聚合的组合物的方法,可通过聚合根据本发明的组合物获得的牙科材料和使用选自以下的物质:具有环的杂环胺 构成带有至少一个N-原子的环的至少一个N原子和五个或更少的原子,或者ROMP中的缓凝剂等两种或更多种物质的混合物。
    • 5. 发明授权
    • Dental composition, kit of parts and use thereof
    • 牙科组成,零件套件及其用途
    • US08710113B2
    • 2014-04-29
    • US13807553
    • 2011-06-24
    • Adrian S. EckertMichael M. CubBettina HailandMarion B. KestelKarsten DedeUwe H. HoheiselGioacchino RaiaChristoph ThalackerReinhold HechtThomas LuchterhandtPeter BissingerWolf Steiger
    • Adrian S. EckertMichael M. CubBettina HailandMarion B. KestelKarsten DedeUwe H. HoheiselGioacchino RaiaChristoph ThalackerReinhold HechtThomas LuchterhandtPeter BissingerWolf Steiger
    • A61K6/00B01F3/04C08F2/46C08G18/67C08G61/04
    • A61K6/083A61K6/0023A61K6/09C07C271/16C07C2603/64C07C2603/66C08L33/00C08L75/16
    • The invention relates to a dental composition comprising a) a compound (A) with the following features: only one backbone unit (U) with 6 to 20 carbon atoms, at least 6 carbon atoms thereof forming an aromatic or an aliphatic cyclic moiety, the remaining carbon atoms either being part of substituents pending from the cyclic moiety or being part of bridging groups to spacer units, wherein one or more of the remaining carbon atoms can be replaced by an oxygen atom, the backbone unit not comprising a bisphenol structure and halogen atoms, one or two unit(s) (S) being connected to the backbone unit (U) via an ether linkage, at least one unit (S) comprising a —CH2-CH2-CH2-CH2-O—CH2-CH(Q)-OG moiety or a —CH2-CH(OG)-CH2-OM moiety or a mixture of these two types of moieties within one unit (S), with G comprising at least one polymerizable moiety and an urethane moiety, the urethane moiety acting as connecting element to unit(s) (S), and M comprising at least one group selected from acroyl, methacroyl, aryl, mixtures and combinations thereof, Q comprising at least one group selected from hydrogen, methyl, phenyl, phenoxymethyl, mixtures and combinations thereof, and with the proviso that onto the backbone unit (U) at least two substituents are attached, each bearing at least one group G, wherein in the case where only one unit (S) is present, the group G not being part of said unit (S) is located in the further substituent pending from unit (U), b) a filler (B) and c) an initiator (C).
    • 本发明涉及牙科用组合物,其包含a)具有以下特征的化合物(A):只有一个具有6至20个碳原子的骨架单元(U),其至少6个碳原子形成芳族或脂族环状部分, 剩余的碳原子是作为从环状部分悬挂的取代基的一部分或作为间隔基单元的桥连基团的一部分,其中一个或多个剩余的碳原子可被氧原子代替,所述主链单元不包含双酚结构和卤素 原子,一个或两个单元(S)经由醚键连接至主体单元(U),至少一个包含-CH 2 -CH 2 -CH 2 -CH 2 -O-CH 2 -CH(CH 3) Q)-OG部分或-CH2-CH(OG)-CH2-OM部分或这些两种类型的部分在一个单位(S)内的混合物,其中G包含至少一个可聚合部分和氨基甲酸酯部分,氨基甲酸酯 用作单元(S)的连接元件的部分,和M包含至少一个选自acroy的基团 Q,其包含至少一个选自氢,甲基,苯基,苯氧基甲基,其混合物和组合的基团,并且条件是在主链单元(U)上连接至少两个取代基 各自具有至少一个基团G,其中在仅存在一个单元(S)的情况下,不是所述单元(S)的一部分的组G位于从单元(U)悬挂的另外的取代基中,b) 填料(B)和c)引发剂(C)。
    • 6. 发明申请
    • DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF
    • 牙齿组合物,零件套件及其用途
    • US20130109777A1
    • 2013-05-02
    • US13807553
    • 2011-06-24
    • Adrian S. EckertMichael M. CubBettina HailandMarion B. KestelKarsten DedeUwe H. HoheiselGioacchino RaiaChristoph ThalackerReinhold HechtThomas LuchterhandtPeter BissingerWolf Steiger
    • Adrian S. EckertMichael M. CubBettina HailandMarion B. KestelKarsten DedeUwe H. HoheiselGioacchino RaiaChristoph ThalackerReinhold HechtThomas LuchterhandtPeter BissingerWolf Steiger
    • A61K6/083
    • A61K6/083A61K6/0023A61K6/09C07C271/16C07C2603/64C07C2603/66C08L33/00C08L75/16
    • The invention relates to a dental composition comprising a) a compound (A) with the following features: only one backbone unit (U) with 6 to 20 carbon atoms, at least 6 carbon atoms thereof forming an aromatic or an aliphatic cyclic moiety, the remaining carbon atoms either being part of substituents pending from the cyclic moiety or being part of bridging groups to spacer units, wherein one or more of the remaining carbon atoms can be replaced by an oxygen atom, the backbone unit not comprising a bisphenol structure and halogen atoms, one or two unit(s) (S) being connected to the backbone unit (U) via an ether linkage, at least one unit (S) comprising a —CH2-CH2-CH2-CH2-O—CH2-CH(Q)-OG moiety or a —CH2-CH(OG)-CH2-OM moiety or a mixture of these two types of moieties within one unit (S), with G comprising at least one polymerizable moiety and an urethane moiety, the urethane moiety acting as connecting element to unit(s) (S), and M comprising at least one group selected from acroyl, methacroyl, aryl, mixtures and combinations thereof, Q comprising at least one group selected from hydrogen, methyl, phenyl, phenoxymethyl, mixtures and combinations thereof, and with the proviso that onto the backbone unit (U) at least two substituents are attached, each bearing at least one group G, wherein in the case where only one unit (S) is present, the group G not being part of said unit (S) is located in the further substituent pending from unit (U), b) a filler (B) and c) an initiator (C).
    • 本发明涉及牙科用组合物,其包含a)具有以下特征的化合物(A):只有一个具有6至20个碳原子的骨架单元(U),其至少6个碳原子形成芳族或脂族环状部分, 剩余的碳原子是作为从环状部分悬挂的取代基的一部分或作为间隔基单元的桥连基团的一部分,其中一个或多个剩余的碳原子可被氧原子代替,所述主链单元不包含双酚结构和卤素 原子,一个或两个单元(S)经由醚键连接至主体单元(U),至少一个包含-CH 2 -CH 2 -CH 2 -CH 2 -O-CH 2 -CH(CH 3) Q)-OG部分或-CH2-CH(OG)-CH2-OM部分或这些两种类型的部分在一个单位(S)内的混合物,其中G包含至少一个可聚合部分和氨基甲酸酯部分,氨基甲酸酯 用作单元(S)的连接元件的部分,和M包含至少一个选自丙酰基,甲基的基团 包括至少一个选自氢,甲基,苯基,苯氧基甲基,其混合物和组合的基团,并且条件是在主链单元(U)上连接至少两个取代基,每个 具有至少一个基团G,其中在仅存在一个单元(S)的情况下,不是所述单元(S)的一部分的基团G位于从单元(U)悬挂的另外的取代基中,b)填料 (B)和c)引发剂(C)。
    • 7. 发明授权
    • Composition containing aziridino groups and use thereof
    • 含有氮丙啶基的组合物及其用途
    • US08022113B2
    • 2011-09-20
    • US12278983
    • 2007-02-08
    • Thomas KlettkeCornelia B. FuehrerPeter Bissinger
    • Thomas KlettkeCornelia B. FuehrerPeter Bissinger
    • A61K6/10A61C9/00C08C19/22
    • A61K6/10C08G73/0206C08L79/02
    • The invention relates to a composition comprising a prepolymer as component (A), wherein the prepolymer comprises aziridino groups and is characterized by an equivalent weight EW1, a crosslinker as component (B), wherein the crosslinker has a structure being different from the structure of the prepolymer and comprises aziridino groups and is characterized by an equivalent weight EW2, an initiator as component (C) being able to start curing of the composition, optionally filler(s) as component (D) and optionally additive(s) as component (E), wherein equivalent weight is defined as (molecular mass of the molecule)/(number of aziridino groups present in the molecule) and wherein EW1>EW2. The invention also relates to the use of the composition for coating, sealing, moulding, adhering, making impressions, producing a dental material.
    • 本发明涉及包含作为组分(A)的预聚物的组合物,其中预聚物包括氮丙啶基,其特征在于当量重量EW1,作为组分(B)的交联剂,其中交联剂的结构不同于 预聚物并且包含氮丙啶基并且其特征在于当量重量EW2,作为组分(C)的引发剂能够开始组合物的固化,任选地作为组分(D)的填料和任选的添加剂作为组分( E),其中当量定义为(分子的分子量)/(分子中存在的氮丙啶基数),其中EW1> EW2。 本发明还涉及组合物用于涂覆,密封,模制,粘附,制造印模,制造牙科材料的用途。