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1. 发明申请

WO2008131920A8 INSTRUMENT AND SYSTEM FOR PRODUCING A SAMPLE OF A BODY LIQUID AND FOR ANALYSIS THEREOF 审中-公开
标题翻译：用于生产体液样品及其分析的仪器和系统
公开(公告)号：WO2008131920A8
公开(公告)日：2009-11-05
申请号：PCT/EP2008003355
申请日：2008-04-25
申请人： ROCHE DIAGNOSTICS GMBH , HOFFMANN LA ROCHE , KRAEMER UWE , ZIMMER VOLKER , ROEDEL WOLFGANG , LIST HANS , FREY STEPHAN-MICHAEL , HOERAUF CHRISTIAN , PATEL PAUL
发明人： KRAEMER UWE , ZIMMER VOLKER , ROEDEL WOLFGANG , LIST HANS , FREY STEPHAN-MICHAEL , HOERAUF CHRISTIAN , PATEL PAUL
IPC分类号： A61B5/155 , A61B5/00
CPC分类号： A61B5/15194 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150183 , A61B5/150358 , A61B5/150389 , A61B5/150503 , A61B5/15113 , A61B5/15117 , A61B5/15128 , A61B5/1519 , A61B5/157
摘要： Instrument for producing a sample of body liquid for analysis by piercing the skin with a lancing element (12) having a skin piercing tip. The instrument (11) has a housing (13) and a lancing drive (14) for driving a lancing element (12) connected thereto in a puncturing movement. A pressure ring (1) surrounds a skin contact opening (4) and is adapted for pressing against the skin such that the skin (3) bulges into the opening (4) for promoting expression of body fluid. The skin contact opening (4) has an opening area corresponding to a circle with a diameter of at least 3 mm and at most 8 mm, and the instrument comprises a pressing force control device (37) for controlling the pressing force between the pressure ring (1) and the skin (3) at the time of triggering the puncturing movement, to be at least 3 N and at most 8 N.
摘要翻译：用于通过用具有皮肤刺穿尖端的穿刺元件（12）刺穿皮肤来生产用于分析的体液样品的仪器。仪器（11）具有壳体（13）和用于在穿刺运动中驱动与其连接的穿刺元件（12）的穿刺驱动器（14）。压力环（1）围绕皮肤接触开口（4）并且适于压靠皮肤，使得皮肤（3）凸起到开口（4）中以促进体液的表达。皮肤接触开口（4）具有对应于直径为至少3mm且至多为8mm的圆的开口面积，并且该仪器包括用于控制压力环之间的按压力的按压力控制装置（37）（1）和皮肤（3）在触发穿刺运动时为至少3N且至多8N。

2. 发明申请

WO2008131920A3 INSTRUMENT AND SYSTEM FOR PRODUCING A SAMPLE OF A BODY LIQUID AND FOR ANALYSIS THEREOF 审中-公开
标题翻译：用于生产体液样品及其分析的仪器和系统
公开(公告)号：WO2008131920A3
公开(公告)日：2009-03-19
申请号：PCT/EP2008003355
申请日：2008-04-25
申请人： ROCHE DIAGNOSTICS GMBH , HOFFMANN LA ROCHE , ZIMMER VOLKER , KRAEMER UWE , ROEDEL WOLFGANG , LIST HANS , FREY STEPHAN-MICHAEL , HOERAUF CHRISTIAN , PATEL PAUL
发明人： KRAEMER UWE , ROEDEL WOLFGANG , LIST HANS , FREY STEPHAN-MICHAEL , HOERAUF CHRISTIAN , PATEL PAUL
IPC分类号： A61B5/155 , A61B5/00
CPC分类号： A61B5/15194 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150183 , A61B5/150358 , A61B5/150389 , A61B5/150503 , A61B5/15113 , A61B5/15117 , A61B5/15128 , A61B5/1519 , A61B5/157
摘要： Instrument for producing a sample of body liquid for analysis by piercing the skin with a lancing element (12) having a skin piercing tip. The instrument (11 ) has a housing (13) and a lancing drive (14) for driving a lancing element (12) connected thereto in a puncturing movement. A pressure ring (1 ) surrounds a skin contact opening (4) and is adapted for pressing against the skin such that the skin (3) bulges into the opening (4) for promoting expression of body fluid. The skin contact opening (4) has an opening area corresponding to a circle with a diameter of at least 3 mm and at most 8 mm, and the instrument comprises a pressing force control device (37) for controlling the pressing force between the pressure ring (1 ) and the skin (3) at the time of triggering the puncturing movement, to be at least 3 N and at most 8 N.
摘要翻译：用于通过用具有皮肤刺穿尖端的穿刺元件（12）刺穿皮肤来生产用于分析的体液样品的仪器。仪器（11）具有壳体（13）和用于在穿刺运动中驱动与其连接的穿刺元件（12）的穿刺驱动器（14）。压力环（1）围绕皮肤接触开口（4）并且适于压靠皮肤，使得皮肤（3）凸起到开口（4）中以促进体液的表达。皮肤接触开口（4）具有对应于直径为至少3mm且至多为8mm的圆的开口面积，并且该仪器包括用于控制压力环之间的按压力的按压力控制装置（37）（1）和皮肤（3）在触发穿刺运动时为至少3N且至多8N。

3. 发明申请

WO2009027010A2 ANALYSIS SYSTEM FOR DETERMINING AN ANALYTE IN A BODY FLUID, MAGAZINE FOR AN ANALYSIS SYSTEM, INTEGRATED SAMPLE ACQUISITION AND ANALYZING ELEMENT, AND METHOD FOR ANALYZING A BODY FLUID 审中-公开
标题翻译：用于确定体液中分析物的分析系统，用于分析系统的杂志，集成样品获取和分析单元以及用于分析体液的方法
公开(公告)号：WO2009027010A2
公开(公告)日：2009-03-05
申请号：PCT/EP2008006456
申请日：2008-08-06
申请人： ROCHE DIAGNOSTICS GMBH , HOFFMANN LA ROCHE , LIST HANS , FREY STEPHAN-MICHAEL , FLUEGGE KAI
发明人： LIST HANS , FREY STEPHAN-MICHAEL , FLUEGGE KAI
IPC分类号： A61B5/15
CPC分类号： A61B5/1405 , A61B5/150022 , A61B5/150358 , A61B5/150419 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/15115 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15174 , A61B5/15176 , A61B5/157
摘要： Analysis system for determining an analyte in a body fluid, comprising a reusable analysis instrument (2) and a magazine (3) having a plurality of flat, disposable, integrated sample acquisition and analyzing elements, each comprising a puncturing element (23) and an analyzing element (20) and have two major surfaces. The analysis instrument (2) comprises a drive, by which the puncture movement of the puncturing element (23) is driven, to move it on a movement path in the puncturing direction during a propulsion phase and opposite to the puncturing direction after reaching a reversal point of the puncture movement during a retraction phase, a coupling unit (7), which is adapted for coupling an integrated sample acquisition and analyzing element to the drive, a measuring and evaluation unit (8) for measuring a measurement variable characteristic for determining an analyte and for deriving a desired analysis result, and a holder for receiving the magazine (3). The magazine (3) comprises a housing having a plurality of elongate chambers located neighboring one another. The chamber (9) are separated by two side walls (10) running in the longitudinal direction of the chambers (9), and have a height and length greater than the distance of two neighboring side walls (10). The chambers (9) have major sides (11 ) delimited by the side walls (10) and two long and two short minor sides (12, 13) extending between the side walls (10). The chamber (9) contain an integrated sample acquisition and analyzing element, whose puncturing element has a coupling structure (29) and is movable on the movement path of the puncture movement in the puncturing direction. The chambers (9) have an exit opening (14) on one of their minor sides (12, 13) for allowing at least partial exiting out of the chamber of the puncturing element (23) moved on the movement path. The coupling unit (7) has a coupling element (35). The chambers (9) of the magazine (3) are accessible for the coupling element (35) on one of their long minor sides (12) such that the coupling element (35) can be coupled to the coupling structure (29) of the puncturing element (23) in a formfitting way, when the puncturing element (23) is positioned in the chamber (9) of the magazine (3) and the magazine (3) is located in the holder.
摘要翻译：用于确定体液中的分析物的分析系统，包括可重复使用的分析仪器（2）和具有多个平坦的一次性的一体式样品采集和分析元件的盒（3），每个包括穿刺元件（23）和分析元件（20）并具有两个主表面。分析仪器（2）包括驱动器，通过该驱动器，穿刺元件（23）的穿刺运动被驱动，以在推进阶段中在穿刺方向的移动路径上移动，并且在达到反转之后与穿刺方向相反在退避阶段期间的穿刺运动的点;耦合单元（7），其适于将集成采样和分析元件耦合到驱动器;测量和评估单元（8），用于测量用于确定分析物和用于获得期望的分析结果，以及用于接收杂志（3）的保持器。杂志（3）包括具有彼此相邻的多个细长室的壳体。室（9）由沿着室（9）的纵向延伸的两个侧壁（10）分开，并且具有大于两个相邻侧壁（10）的距离的高度和长度。室（9）具有由侧壁（10）限定的主侧面（11）和在侧壁（10）之间延伸的两个长的和两个短的短边（12,13）。腔室（9）包含一个集成的采样和分析元件，其穿刺元件具有耦合结构（29），并且可以在穿刺方向上的穿刺运动的移动路径上移动。腔室（9）在其小侧（12,13）中的一个上具有出口开口（14），用于允许至少部分地离开在移动路径上移动的穿刺元件（23）的腔室。联接单元（7）具有联接元件（35）。盒（3）的腔室（9）可在其长的较小侧面（12）中的一个上接近用于联接元件（35），使得联接元件（35）能够联接到当穿刺元件（23）位于钉仓（3）的腔室（9）中并且刀库（3）位于保持器中时，穿孔元件（23）以成形方式。

4. 发明申请

WO2011035867A8 BODY FLUID LANCING, ACQUIRING, AND TESTING CARTRIDGE DESIGN 审中-公开
标题翻译：身体流体，采集和测试盒设计
公开(公告)号：WO2011035867A8
公开(公告)日：2012-04-19
申请号：PCT/EP2010005688
申请日：2010-09-16
申请人： ROCHE DIAGNOSTICS GMBH , HOFFMANN LA ROCHE
发明人： ROE STEVEN N , FREY STEPHAN-MICHAEL
IPC分类号： A61B5/151 , A61B5/157
CPC分类号： A61B5/1411 , A61B5/150022 , A61B5/150068 , A61B5/150083 , A61B5/150183 , A61B5/150198 , A61B5/150282 , A61B5/150358 , A61B5/150419 , A61B5/150435 , A61B5/150503 , A61B5/150526 , A61B5/150572 , A61B5/150954 , A61B5/15109 , A61B5/15117 , A61B5/15128 , A61B5/15146 , A61B5/15151 , A61B5/15163 , A61B5/15176 , A61B5/157 , Y10T29/49826
摘要： A lancet wheel (22) having a rim (23) with a plurality of lancets (24) extending radially inward from the rim is dropped in a circular frame (30) having a plurality of spokes forming a plurality of chambers (32) for facilitating drop -in assembly of the modular lancet wheel with the frame. A test ring (26) having a plurality of test sections (28) is assembled on the frame such that one test section is located adjacent each lancet to form an integrated cartridge (20). Each lancet includes a lancet tip (46) defining a capillary groove sized to collect a body fluid sample from the incision via capillary action. The lancet tip exits the chamber to form the incision in skin, the capillary groove collects the body fluid sample, the lancet tip retracts into the chamber, and a portion of the lancet contacts the test section to transfer the sample from the capillary groove to the test section to analyze the sample.
摘要翻译：具有边缘（23）的柳叶刀轮（22）被落在具有多个辐条的圆形框架（30）中，该圆形框架（30）形成有多个腔室（32），以便于模块化柳叶刀轮与框架的组合。具有多个测试部分（28）的测试环（26）组装在框架上，使得一个测试部分位于每个刺血针附近以形成集成的盒（20）。每个刺血针包括一个刺血针尖端（46），其限定毛细槽，其尺寸适于通过毛细管作用从切口收集体液样品。刺血针尖端离开腔室，在皮肤上形成切口，毛细管槽收集体液样本，刺血针尖端缩回到腔室中，一部分刺血针与测试部分接触，将样品从毛细管槽转移到测试部分分析样品。

5. 发明申请

WO2011035867A3 BODY FLUID LANCING, ACQUIRING, AND TESTING CARTRIDGE DESIGN 审中-公开
标题翻译：身体流体，采集和测试盒设计
公开(公告)号：WO2011035867A3
公开(公告)日：2011-05-19
申请号：PCT/EP2010005688
申请日：2010-09-16
申请人： ROCHE DIAGNOSTICS GMBH , HOFFMANN LA ROCHE
发明人： ROE STEVEN N , FREY STEPHAN-MICHAEL
IPC分类号： A61B5/151 , A61B5/157
CPC分类号： A61B5/1411 , A61B5/150022 , A61B5/150068 , A61B5/150083 , A61B5/150183 , A61B5/150198 , A61B5/150282 , A61B5/150358 , A61B5/150419 , A61B5/150435 , A61B5/150503 , A61B5/150526 , A61B5/150572 , A61B5/150954 , A61B5/15109 , A61B5/15117 , A61B5/15128 , A61B5/15146 , A61B5/15151 , A61B5/15163 , A61B5/15176 , A61B5/157 , Y10T29/49826
摘要： A lancet wheel (22) having a rim (23) with a plurality of lancets (24) extending radially inward from the rim is dropped in a circular frame (30) having a plurality of spokes forming a plurality of chambers (32) for facilitating drop -in assembly of the modular lancet wheel with the frame. A test ring (26) having a plurality of test sections (28) is assembled on the frame such that one test section is located adjacent each lancet to form an integrated cartridge (20). Each lancet includes a lancet tip (46) defining a capillary groove sized to collect a body fluid sample from the incision via capillary action. The lancet tip exits the chamber to form the incision in skin, the capillary groove collects the body fluid sample, the lancet tip retracts into the chamber, and a portion of the lancet contacts the test section to transfer the sample from the capillary groove to the test section to analyze the sample.
摘要翻译：具有边缘（23）的柳叶刀轮（22）被落在具有多个辐条的圆形框架（30）中，该圆形框架（30）形成有多个腔室（32），以便于模块化柳叶刀轮与框架的组合。具有多个测试部分（28）的测试环（26）组装在框架上，使得一个测试部分位于每个刺血针附近以形成集成的盒（20）。每个刺血针包括一个刺血针尖端（46），其限定毛细槽，其尺寸适于通过毛细管作用从切口收集体液样品。刺血针尖端离开腔室，在皮肤上形成切口，毛细管槽收集体液样本，刺血针尖端缩回到腔室中，一部分刺血针与测试部分接触，将样品从毛细管槽转移到测试部分分析样品。

6. 发明专利

ES2392204T3 Instrumento y sistema para producir una muestra de un líquido del cuerpo y para el análisis del mismo 未知
公开(公告)号：ES2392204T3
公开(公告)日：2012-12-05
申请号：ES08749134
申请日：2008-04-25
申请人： ROCHE DIAGNOSTICS GMBH , HOFFMANN LA ROCHE
发明人： KRAEMER UWE , ZIMMER VOLKER , ROEDEL WOLFGANG , LIST HANS , FREY STEPHAN-MICHAEL , HOERAUF CHRISTIAN , PATEL PAUL
IPC分类号： A61B5/155 , A61B5/145 , A61B5/1455 , A61B5/157
摘要： Sistema para la producción de una muestra de líquido del cuerpo mediante la perforación de la piel y parael análisis de la muestra, dicho sistema comprendiendo un instrumento reutilizable sostenido con la mano (11) y unelemento de corte con lanceta (12) el cual está adaptado para ser conectado de forma intercambiable a unaccionamiento (14) del instrumento, dicho elemento de corte con lanceta (12) estando provisto de una punta deperforación de la piel (7) y un dispositivo de recolecta de la muestra (36) para recoger una cantidad de líquido demuestra requerido para el análisis, el sistema adicionalmente comprendiendo un elemento de análisis desechable(21), dicho instrumento (11) comprendiendo:- un alojamiento (13),- un accionamiento de corte con lanceta (14) en el interior de dicho alojamiento (13) para ser conectado a unelemento de corte con lanceta (12) y para el accionamiento de un elemento de corte con lanceta (12) conectado almismo en un movimiento de pinchazo en el cual el elemento de corte con lanceta (12) se mueve, después deldisparo del movimiento de pinchazo, en una dirección del pinchazo hasta que llega a un punto (P) dedesplazamiento máximo y en un sentido inverso después de que haya llegado al punto (P) de desplazamientomáximo,- un anillo de presión (1) que rodea un orificio de contacto con la piel (4) y que está adaptado para serpresionado contra la piel de tal modo que la piel (3) se abulta en el interior del orificio (4) para promover la extracciónde fluido del cuerpo,- un dispositivo de soporte (20) para sostener un elemento de análisis en dicho alojamiento de tal modo queuna muestra de líquido del cuerpo es transportada al mismo desde el dispositivo de recolecta de la muestra (36)para el análisis,en el que el instrumento comprende un dispositivo de control de la fuerza de presión (37) para controlar la fuerza depresión entre el anillo de presión (1) y la piel (3) y un dispositivo para disparar automáticamente el movimiento depinchazo cuando la fuerza de presión corresponde a un valor mínimo previamente determinado de por lo 3 N, y unperiodo de tiempo de interacción mínimo, que empieza a partir del disparo automático del movimiento de pinchazo,durante el cual cada usuario debe por lo menos interactuar con el instrumento mediante una fuerza de presión entrela piel y el anillo de presión del instrumento para el corte con lanceta, extracción de líquido de muestra desde eltejido y recogida de una cantidad suficiente de líquido de muestra para el análisis, que es como máximo 3 segundos.

7. 发明专利

DK2205152T3 Engangsindretning til analyse af legemsvæske 未知
公开(公告)号：DK2205152T3
公开(公告)日：2012-02-06
申请号：DK08804095
申请日：2008-09-12
申请人： ROCHE DIAGNOSTICS GMBH , HOFFMANN LA ROCHE
发明人： FREY STEPHAN-MICHAEL , LIST HANS , BRAENDLE HANSJOERG , ROE STEVEN N , HOERAUF CHRISTIAN
IPC分类号： A61B5/151

8. 发明专利

JP2008253752A Analysis device with exchangeable test element magazine 有权
标题翻译：具有可交换测试元件杂志的分析装置
公开(公告)号：JP2008253752A
公开(公告)日：2008-10-23
申请号：JP2008063276
申请日：2008-03-12
申请人： F Hoffmann-La Roche Ag , エフホフマン−ラロッシュアクチェンゲゼルシャフト
发明人： LIST HANS , FREY STEPHAN-MICHAEL , ZIMMER VOLKER
IPC分类号： A61B5/157 , A61B5/151 , A61B5/155 , G01N35/04
CPC分类号： G01N33/48757 , G01N2035/00039 , G01N2035/00277 , Y10T436/193333
摘要： PROBLEM TO BE SOLVED: To provide a measurement system including a magazine connected to an analysis device and housing a plurality of consumer elements. SOLUTION: The invention provides the measurement system 110 including an analysis device 114 with at least a measurement function and/or a sample collection function, and also at least one magazine 112 for receiving at least one consumer element 122. The magazine includes a magazine housing 120 with at least one opening 128, 130. The magazine is designed as an exchangeable magazine 112 that can be connected to the analysis device 114. The analysis device 114 has a closure means 116 with at least one sealing element 118. The sealing element is designed to supply at least one consumer element 122 from the opening 128, 130, and when the magazine 112 is in the closed state, the sealing element remains in the opening 128, 130, thereby sealing it. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种包括连接到分析装置并容纳多个消费者元件的盒的测量系统。解决方案：本发明提供了包括具有至少测量功能和/或样品收集功能的分析装置114的测量系统110，以及至少一个用于接收至少一个消费者元件122的盒112。盒包括具有至少一个开口128,130的仓库120.该仓被设计为可连接到分析装置114的可更换仓库112.分析装置114具有带有至少一个密封元件118的封闭装置116。密封元件被设计成从开口128,130供应至少一个消费者元件122，并且当料盒112处于关闭状态时，密封元件保持在开口128,130中，从而将其密封。版权所有（C）2009，JPO＆INPIT

9. 发明专利

ES2376025T3 DISPOSITIVO DE UN SOLO USO PARA ANALIZAR UN FLUIDO CORPORAL. 未知
公开(公告)号：ES2376025T3
公开(公告)日：2012-03-08
申请号：ES08804095
申请日：2008-09-12
申请人： HOFFMANN LA ROCHE , HOFFMANN LA ROCHE
发明人： FREY STEPHAN-MICHAEL , LIST HANS , BRAENDLE HANSJOERG , HOERAUF CHRISTIAN , ROE STEVEN N
IPC分类号： A61B5/151
摘要： Un dispositivo de un solo uso para analizar un fluido corporal, especialmente para ensayos de azúcar en sangre el cual dispositivo comprende un recipiente (16) el cual puede estar insertado en un aparato de medición (10), un elemento de muestreo (28) previsto en el recipiente para perforar la piel de una parte del cuerpo y obtener una muestra de fluido corporal, y un elemento de ensayo (30), para la recepción del fluido corporal obtenido en la perforación de la piel, en donde el elemento de ensayo está fijo en una cámara de retención (26) del recipiente, caracterizado porque, el elemento de muestreo está configurado en la misma cámara de retención, de forma que: - está separado a una cierta distancia del elemento de ensayo formando un espacio libre (38) entre el elemento de muestreo y el elemento de ensayo, en un estado inicial, y - está en contacto con el elemento de ensayo para la transferencia del fluido corporal en un estado de transferencia, después del perforado de la piel cuando el elemento de muestreo está en la cámara de retención.

10. 发明专利

PL2422693T3 Urządzenie i sposób przeprowadzania co najmniej jednej funkcji medycznej 未知
公开(公告)号：PL2422693T3
公开(公告)日：2019-05-31
申请号：PL10174253
申请日：2010-08-27
申请人： HOFFMANN LA ROCHE
发明人： FREY STEPHAN-MICHAEL , WALTER HELMUT , BRAUN JÜRGEN , PFRANG JÜRGEN
IPC分类号： A61B5/145 , A61B5/00

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