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    • 6. 发明申请
    • ABLATIVE, RENEWABLE, MULTI-FUNCTIONAL PROTECTIVE COATING FOR DENTAL SURFACES
    • 可口可乐,牙科表面多功能保护涂层
    • WO2016077710A1
    • 2016-05-19
    • PCT/US2015/060603
    • 2015-11-13
    • RHODIA OPERATIONSREIERSON, Robert, LeeBENDEJACQ, Denis
    • REIERSON, Robert, LeeBENDEJACQ, Denis
    • A61K8/55A61K8/49A61K8/72A61K8/02A61Q11/00
    • A61K8/817A61K8/8164A61K2800/28A61Q11/00C07F9/091C07F9/5721
    • An oral care composition in the form of a toothpaste, tooth gel, dentifrice, tooth powder, prophy paste, mouthwash, rinse, tooth mousse, dental floss, chewing gum, soluble oral care strip or film for direct application or attachment to an oral surface, or lozenge for combating dental caries, erosion, hypersensitivity, and/or staining that includes an orally acceptable carrier and a copolymer of a first a, β-ethylenically unsaturated phosphate compound (A); and one or more a, β-ethylenically unsaturated co- monomers, at least one of which is other than an allyl-functional co-monomer, wherein (A) is an allyl phosphate compound of formula (A): [CH 2 =CH-CH 2 -O(R 1 O) a (R 2 O) b ] x P(O)(OM) 3-x wherein, R 1 is a substituted or unsubstituted (C 2 -C 4 ) alkylene moiety; R 2 is a substituted or unsubstituted (C 2 -C 4 ) alkylene moiety; M is identical or different, hydrogen, alkali metal, ammonium, protonated alkyl amine, protonated alkanolamine, or protonated basic amino acid; X is 1 or 2, a is from 1 to 20; and b is from 0 to 20. Methods for combating dental caries, erosion, hypersensitivity, and/or staining are also provided.
    • 口腔护理组合物,其形式为牙膏,牙胶,洁牙剂,牙粉,漱口剂,漱口剂,漂洗剂,牙膏,牙线,口香糖,可直接使用或附着于口腔表面的可溶性口腔护理条或膜 ,或抗皱龋齿,侵蚀,超敏反应和/或染色的锭剂,包括口服可接受的载体和第一种α,β-烯属不饱和磷酸酯化合物(A)的共聚物; 和一种或多种α-烯属不饱和共聚单体,其中至少一种不是烯丙基官能的共聚单体,其中(A)是式(A)的烯丙基磷酸酯化合物:[CH 2 = CH- CH2-O(R1O)a(R2O)b] xP(O)(OM)3-x其中R1是取代或未取代的(C2-C4)亚烷基部分; R2是取代或未取代的(C2-C4)亚烷基部分; M是相同或不同的,氢,碱金属,铵,质子化的烷基胺,质子化的链烷醇胺或质子化的碱性氨基酸; X为1或2,a为1至20; 并且b为0至20.还提供了防止龋齿,侵蚀,超敏反应和/或染色的方法。
    • 9. 发明申请
    • IMPROVED AMINOPHOSPHINATE CO-POLYMER
    • 改进的氨基磷酸酯共聚物
    • WO2007017647A1
    • 2007-02-15
    • PCT/GB2006/002920
    • 2006-08-04
    • RHODIA INC.WOODWARD, GaryOTTER, GrahamZAFAR, ShaziaBENDEJACQ, DenisANTHONY, Olivier
    • WOODWARD, GaryOTTER, GrahamZAFAR, ShaziaBENDEJACQ, DenisANTHONY, Olivier
    • C08G79/04
    • C08G79/02C08G79/04C08K5/5313C08L53/00C11D3/3784C08L2666/02
    • The present invention relates to a co-polymer or oligomer thereof, of the formula (I) wherein: -R and R' are each independently selected from hydrogen, a hydroxyl group, a carboxyl group, an alkyl, aryl or alkaryl group or a hydroxy - or carboxy - substituted alkyl, aryl or alkaryl group, provided that R and R' together have a total of less than 23 carbon atoms; -X is hydrogen or a cation or an alkyl group; - n and n', identical or different, are greater than or equal to 0; - each of R y groups, which may be the same or different, and each of the R x groups, which may be the same or different, is hydrogen, an optionally substituted alkyl, cycloalkyl, alkenyl, aryl, aralkyl, alkaryl or alkoxyalkyl group of 1 -20 carbon atoms each of which may be optionally substituted once or more than once; - R z is an alkane group or a substituted alkane group or a heterocyclic group; - m and m', identical or different, are zero or from 1 to 100; - p is zero or from 1 to 100; and - each of the R v groups, which may be the same or different, is hydrogen, an optionally substituted alkyl, cycloalkyl, alkenyl, aryl, aralkyl, alkaryl or alkoxyalkyl group of 1 -20 carbon atoms each of which may be optionally substituted once or more than once.
    • 本发明涉及式(I)的共聚物或低聚物,其中:-R和R'各自独立地选自氢,羟基,羧基,烷基,芳基或烷芳基或 羟基或羧基取代的烷基,芳基或烷芳基,条件是R和R'总共具有少于23个碳原子; -X是氢或阳离子或烷基; - n和n'相同或不同,大于或等于0; 每个R y可以相同或不同,R x可以相同或不同的每一个可以是氢,任选地 取代的烷基,环烷基,烯基,芳基,芳烷基,烷芳基或1〜20个碳原子的烷氧基烷基,其中每个可以任选被一次或多于一次取代; R z是烷烃基或取代的烷烃基或杂环基; - m和m'相同或不同,为零或1至100; - p为零或1至100; 和 - 可以相同或不同的每一个R 12是氢,1-20个碳原子的任选取代的烷基,环烷基,烯基,芳基,芳烷基,烷芳基或烷氧基烷基 其中每一个可以任选地被一次或多于一次地取代。