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1. 发明授权

US06764499B2 Medical device handle 有权
标题翻译：医疗器械手柄
公开(公告)号：US06764499B2
公开(公告)日：2004-07-20
申请号：US09861309
申请日：2001-05-18
申请人： R. John D'A. Honey , Marvin O. Andrews , Frank J. Fischer, Jr. , John H. Ward
发明人： R. John D'A. Honey , Marvin O. Andrews , Frank J. Fischer, Jr. , John H. Ward
IPC分类号： A61B1728
CPC分类号： A61B17/2909 , A61B17/221 , A61B2017/0046 , A61B2017/00469 , A61B2017/2212 , A61B2017/292
摘要： A replaceable handle for side loading the proximal end of a medical device therein, which is typically inserted with the operating lumen of an endoscope. The replaceable handle can side-load the proximal end of the device into the handle for added manipulation of the distal end such as in removing a stone from the kidney or ureter leading therefrom. An inner housing is rotatable within an outer housing of the handle to secure the medical device in the housing passageway, and is spring biased to then move proximally with respect to the outer housing, moving the inner control rod of the medical device proximally to withdraw the stone basket mostly into the outer cannula and capture the stone for removal from the patient. A push button in the proximal end portion of the inner housing is depressible to permit insertion or withdrawal of the proximal end of the inner control rod of the stone retriever within the inner housing, and is releasable to secure the inner control rod in the handle.
摘要翻译：用于侧面加载其中的医疗装置的近端的可更换手柄，其通常与内窥镜的操作内腔一起插入。可替换的手柄可以将装置的近端侧向装入手柄，以增加远端的操作，例如从从其引导的肾脏或输尿管上移除石头。内壳体可以在手柄的外壳内旋转，以将医疗装置固定在壳体通道中，并且被弹簧偏压，然后相对于外壳向近侧移动，将医疗装置的内控制杆向近侧移动以撤回石筐主要进入外套管并捕获石头以从患者身上取出。内壳体的近端部分中的按钮是可压下的，以允许在内壳体内的石材回收器的内控制杆的近端插入或取出，并且可释放以将内控制杆固定在手柄中。

2. 发明授权

US06210315B1 Brachytherapy device including an anti-static handle 有权
标题翻译：近距离放射治疗装置包括防静电手柄
公开(公告)号：US06210315B1
公开(公告)日：2001-04-03
申请号：US09354073
申请日：1999-07-15
申请人： Marvin O. Andrews , Frank J. Fischer, Jr. , John H. Ward
发明人： Marvin O. Andrews , Frank J. Fischer, Jr. , John H. Ward
IPC分类号： A61N500
CPC分类号： A61N5/1027 , A61N2005/1011
摘要： A brachytherapy device 10 for exposing to radioactivity a patient includes an elongate member such as a needle or cannula 12 adapted for introduction into the patient and also includes a stylet 14 slideably receivable in a longitudinal throughbore 16 in the needle 12. The device 10 also includes a portion 64 near either the proximal end 18 of the needle 12 or the distal end 24 of the stylet 14 which provides a local, defined amount of friction between the needle 12 and the stylet 14. The device 10 further includes an anti-static handle 34 connected to the needle 12. The handle 34 has an interior ramp surface 40 in communication with the throughbore 16 of the needle 12, frustoconical in shape and possessing an included apical angle of at least about 16°. The localized friction portion 64 can be a crimp or flange 48 on the stylet 14, or a crimp 44 or deformation 46 in or of the needle 12. The handle 34 is preferably composed of a polycarbonate, acrylic or acetal resin (such resins preferably being carbon-filled, or otherwise electro static dissipative), or a hydroscopic nylon blend. The device 10 is particularly advantageous in that the preferred ramp surface 40 in the handle 34 facilitates the insertion of seeds 26 of radioactive material and inert spacers 28 into the needle 12. The anti-static handle 34 eliminates, for practical purposes, the previously encountered risks of static interference, static cling of the spacers 28 and ignition spark generation. Finally, the localized friction portion 64 provides a controlled and predetermined amount of friction between the needle 12 and the stylet 14, preventing the stylet 14 from falling from the needle 12, while also preventing or reducing the risk of unintended ejection of the radioactive seeds 26 and spacers 28. Such friction is advantageously provided virtually the entire time any portion of the stylet 14 is received in the needle 12.
摘要翻译：用于暴露于放射性的患者的近距离放射治疗装置10包括适于引入患者体内的细长构件，例如针或插管12，并且还包括可插入针12中的纵向通孔16中的探针14。设备10还包括靠近针12的近端18或探针14的远端24的部分64，其提供针12和探针14之间的局部限定量的摩擦力。装置10还包括防静电手柄 34连接到针12.手柄34具有与针12的通孔16连通的内部斜面40，其具有截头圆锥形形状并且具有至少约16°的包含顶角。局部摩擦部分64可以是探针14上的压接或凸缘48，或者针12中的针状物44或变形46。手柄34优选由聚碳酸酯，丙烯酸或缩醛树脂（这种树脂优选为碳填充或静电耗散）或吸水尼龙混合物。装置10的特别有利之处在于，手柄34中的优选斜面40便于将放射性材料和惰性间隔物28的种子26插入针12中。为了实际目的，防静电手柄34消除了先前遇到的静电干扰的危险，间隔件28的静电附着和点燃火花的产生。最后，局部摩擦部分64在针12和探针14之间提供可控和预定量的摩擦力，从而防止探针14从针12掉落，同时也防止或减少放射性种子26意外喷射的风险这样的摩擦有利地实际上提供了探针14的任何部分被接收在针

3. 发明授权

US06482178B1 Localization device with anchoring barbs 有权
标题翻译：带定位倒钩的本地化装置
公开(公告)号：US06482178B1
公开(公告)日：2002-11-19
申请号：US09566373
申请日：2000-05-08
申请人： Marvin O. Andrews , Frank J. Fischer, Jr. , John H. Ward
发明人： Marvin O. Andrews , Frank J. Fischer, Jr. , John H. Ward
IPC分类号： A61M5178
CPC分类号： A61B90/39 , A61B90/92 , A61B2017/00349 , A61B2017/00867
摘要： A localization device (10) comprising an outer needle cannula (11), an optional inner sleeve cannula (13) and an anchor stylet comprising a plurality of preformed superelastic alloy wires (12). Once the distal portions (14) of the wires (12) are deployed from the ends of the sleeve and needle cannulae, they function as curved barbs (15) projecting outward to anchor the device into tissue, an organ, or a foreign body. A slidable locking member (18), such as a pin vise, can be included over the outer needle cannula for securing the localization device against a template.
摘要翻译：一种定位装置（10），包括外针套管（11），可选的内套管插管（13）和包括多个预成型的超弹性合金线（12）的锚针管。一旦电线（12）的远端部分（14）从套管和针套管的端部展开，它们就起着向外突出的弯曲倒钩（15）的作用，将装置固定在组织，器官或异物中。诸如针虎钳的可滑动的锁定构件（18）可以包括在外针套管上方，用于将定位装置固定在模板上。

4. 发明授权

US08043282B2 Drainage catheter with extended inflation lumen 有权
标题翻译：排水导管具有延长的充气腔
公开(公告)号：US08043282B2
公开(公告)日：2011-10-25
申请号：US11502779
申请日：2006-08-11
申请人： Frank J. Fischer, Jr. , Tracy E. Willis , Marvin O. Andrews
发明人： Frank J. Fischer, Jr. , Tracy E. Willis , Marvin O. Andrews
IPC分类号： A61M27/00
CPC分类号： A61M25/0017 , A61M25/007 , A61M25/0662 , A61M25/10 , A61M27/00 , A61M2025/0681
摘要： A Foley catheter with a retention balloon includes an elongated inflation tube so that the inflation port used to inflate and deflate the balloon may be maneuvered away from the drainage port of the Foley catheter. If the Foley catheter was placed using a urethral access sheath, the elongated inflation tube allows the surgeon to easily remove the access sheath from the patient.
摘要翻译：具有保持气囊的福利导管包括细长的充气管，使得用于使气囊膨胀和放气的充气端口可以被操纵离开Foley导管的排出口。如果使用尿道通道护套放置Foley导管，则细长的充气管允许外科医生容易地从病人身上移除通路护套。

5. 发明授权

US07766926B2 Sling for supporting tissue 有权
标题翻译：吊for支撑组织
公开(公告)号：US07766926B2
公开(公告)日：2010-08-03
申请号：US10427394
申请日：2003-04-30
申请人： Rodney W. Bosley, Jr. , Umesh H. Patel , Marvin O. Andrews , LiKang Chin , Frank J. Fischer, Jr. , Walter N. Ryan , Peter L. Rosenblatt , J. Stephen Jones
发明人： Rodney W. Bosley, Jr. , Umesh H. Patel , Marvin O. Andrews , LiKang Chin , Frank J. Fischer, Jr. , Walter N. Ryan , Peter L. Rosenblatt , J. Stephen Jones
IPC分类号： A61B17/08 , A61F2/02 , A61F2/00
CPC分类号： A61F2/0045 , A61B17/06109 , A61B2017/0046
摘要： A sling for supporting a urethra in a patient has characteristics for resisting pull-out, roll-over and a combination of both pull-out and roll-over. To facilitate resistance to pull-out, sling material has protuberances or serrations to resist movement once placed in the patient by the surgeon. Improved resistance to roll-over or roll-up is achieved by providing relief on the sling in areas potentially subjected to roll-over forces by endopelvic fascia. The sling may be used on female or male patients, and may be used in conjunction with a wider support portion to support a bladder and a urethra, rather than a urethra alone. The sling may also be used to support other tissues within a patient.
摘要翻译：用于在患者中支撑尿道的吊带具有抵抗拉出，翻转以及拉出和翻转的组合的特征。为了促进拉拔的抗拉力，吊索材料具有突起或锯齿，以便一旦被外科医生放置在病人身上就能抵抗运动。通过在潜在地受到内耳筋膜的翻滚力的区域中的吊带上提供缓解，可以提高对翻滚或卷起的抵抗力。吊索可用于女性或男性患者，并且可以与更宽的支撑部分结合使用以支撑膀胱和尿道，而不是单独使用尿道。吊带也可用于支撑患者体内的其他组织。

6. 发明授权

US07731722B2 Ureteral backstop filter and retrieval device 有权
标题翻译：输尿管支架过滤器和检索装置
公开(公告)号：US07731722B2
公开(公告)日：2010-06-08
申请号：US10902754
申请日：2004-07-28
申请人： Shay Lavelle , Marvin O. Andrews , Frank J. Fischer, Jr. , Walter N. Ryan , Valery Diamant , Stepan Khachin , Nadezda Yasko , Vladimir Khachin
发明人： Shay Lavelle , Marvin O. Andrews , Frank J. Fischer, Jr. , Walter N. Ryan , Valery Diamant , Stepan Khachin , Nadezda Yasko , Vladimir Khachin
IPC分类号： A61B17/22 , A61M29/00
CPC分类号： A61B17/221 , A61B17/32056 , A61B90/39 , A61B2017/2212
摘要： A retrieval device for use in renal, biliary, vascular or other systems of a body includes a collapsible basket in a narrow sheath. A surgeon advances the device beyond an object to be removed from a body, such as a kidneystone, a gallstone, or a thrombus. The surgeon then retracts the sheath or advances the basket from the sheath. The basket deploys only to one side of the sheath. In some embodiments, the periphery of the basket has a flex point to enable the basket to easily collapse into the sheath. If the sheath is adjacent a body vessel, such as a blood vessel or a ureter, the sheath remains adjacent the wall, while the device deploys in such a manner as to seal against the walls of the vessel and block the flow of fragments, emboli, thrombi, or other undesirable objects.
摘要翻译：用于身体的肾，胆管，血管或其他系统的检索装置包括狭窄鞘中的可折叠篮。外科医生将装置推进超过物体以从身体移除，例如儿童骨髓，胆结石或血栓。外科医生然后使护套缩回或者将筐从护套推进。篮子仅部署到护套的一侧。在一些实施例中，篮的周边具有弯曲点，以使篮能够容易地折入鞘中。如果护套与身体容器（例如血管或输尿管）相邻，则护套保持邻近壁，同时该装置以这样的方式展开，以密封血管的壁并阻塞碎片的流动，栓塞，血栓或其他不期望的物体。

7. 发明授权

US08057496B2 Mechanical thrombectomy device 有权
标题翻译：机械性血栓切除装置
公开(公告)号：US08057496B2
公开(公告)日：2011-11-15
申请号：US12245807
申请日：2008-10-06
申请人： Frank J. Fischer, Jr.
发明人： Frank J. Fischer, Jr.
IPC分类号： A61B17/22
CPC分类号： A61B17/221 , A61B2017/22079 , A61B2017/22084 , A61B2017/2212
摘要： A medical device for removing a thrombus from a blood vessel and a process thereof is presented. The device includes an outer sheath with a plurality of lumens. A wire guide inserted through one of the lumens is used to place the device proximate to a thrombus. A chemical lysing agent is used to at least partially lyse the thrombus. A wire basket extended through the first lumen proximate to the thrombus is translated back and forth to generate a force that may be transmitted to the partially lysed thrombus assisting in the formation of smaller fragments. A vacuum coupled to the distal end of the second lumen is used to remove the lysed thrombus fragments.
摘要翻译：提出了用于从血管中除去血栓的医疗装置及其过程。该装置包括具有多个管腔的外护套。插入穿过其中一个管腔的线导向器用于将该装置放置在靠近血栓的位置。使用化学裂解剂至少部分裂解血栓。延伸穿过靠近血栓的第一腔的丝线篮来回转动以产生可以传递到部分裂解的血栓以形成较小碎片的力。使用耦合到第二腔的远端的真空来去除裂解的血栓片段。

8. 发明授权

US09205224B2 Infusion mechanism and method 有权
标题翻译：输液机制及方法
公开(公告)号：US09205224B2
公开(公告)日：2015-12-08
申请号：US12756400
申请日：2010-04-08
申请人： Therese O'Day , Frank J. Fischer, Jr. , Lindsay Koren , Mark Allen Magnuson , Richard Earl Luedemann , Shyam Kuppurathanam , Keith R. Milner
发明人： Therese O'Day , Frank J. Fischer, Jr. , Lindsay Koren , Mark Allen Magnuson , Richard Earl Luedemann , Shyam Kuppurathanam , Keith R. Milner
IPC分类号： A61M25/00 , A61M25/01 , A61M25/09
CPC分类号： A61M25/003 , A61M25/002 , A61M25/007 , A61M25/0108 , A61M2025/004 , A61M2025/0073 , A61M2025/0079 , A61M2025/0183 , A61M2025/09175
摘要： An infusion mechanism for treating an intraluminal site in a patient includes an infusion catheter having an elongate body with a proximal body end defining at least one fluid supply orifice, and a distal body end. The elongate body defines a high head loss lumen in fluid communication with a first set of side ports defining a proximal infusion zone. The elongate body further defines a low head loss lumen in fluid communication with a second set of side ports defining a distal infusion zone.
摘要翻译：用于治疗患者的管腔内部位的输注机构包括具有细长体的输注导管，其具有限定至少一个流体供应孔的近端体端和远端本体端。细长体限定了与限定近端输注区的第一组侧端口流体连通的高头损失腔。细长体进一步限定与限定远端输注区的第二组侧端口流体连通的低头损失腔。

9. 发明申请

US20100087844A1 MECHANICAL THROMBECTOMY DEVICE 有权
标题翻译：机械镜检装置
公开(公告)号：US20100087844A1
公开(公告)日：2010-04-08
申请号：US12245807
申请日：2008-10-06
申请人： Frank J. Fischer, Jr.
发明人： Frank J. Fischer, Jr.
IPC分类号： A61B17/221
CPC分类号： A61B17/221 , A61B2017/22079 , A61B2017/22084 , A61B2017/2212
摘要： A medical device for removing a thrombus from a blood vessel and a process thereof is presented. The device comprises an outer sheath with a plurality of lumens. A wire guide inserted through one of the lumens is used to place the device proximate to a thrombus. A chemical lysin agent is used to at least partially lyse the thrombus. A wire basket extended through the first lumen proximate to the thrombus is translated back and forth to generate a force that may be transmitted to the partially lysed thrombus assisting in the formation of smaller fragments. A vacuum coupled to the distal end of the second lumen is used to remove the lysed thrombus fragments.
摘要翻译：提出了用于从血管中除去血栓的医疗装置及其过程。该装置包括具有多个管腔的外护套。插入穿过其中一个管腔的线导向器用于将该装置放置在靠近血栓的位置。使用化学溶素剂至少部分地裂解血栓。延伸穿过靠近血栓的第一腔的丝线篮来回转动以产生可以传递到部分裂解的血栓以形成较小碎片的力。使用耦合到第二腔的远端的真空来去除裂解的血栓片段。

10. 发明授权

US5250038A Multiple lumen vascular access introducer sheath 失效
标题翻译：多腔血管通路导引鞘
公开(公告)号：US5250038A
公开(公告)日：1993-10-05
申请号：US959289
申请日：1992-10-09
申请人： Richard J. Melker , Frank J. Fischer, Jr.
发明人： Richard J. Melker , Frank J. Fischer, Jr.
IPC分类号： A61M25/08 , A61M25/00 , A61M25/14 , A61M5/00
CPC分类号： A61M25/0032
摘要： A multiple lumen vascular access introducer sheath having a main lumen for introduction of another device such as a catheter therethrough and into the vascular system and a secondary lumen having a cross-sectional area significantly less than that of the main lumen for infusion of small doses of medication therethrough at a controlled rate and directly into the vascular system. The introducer sheath comprises a tubular member of an inelastic, semi-rigid plastic material such as fluorinated ethylene propylene or nylon. The main lumen extends longitudinally through the tubular member and opens at the distal and proximal ends thereof. The secondary lumen is positioned adjacent to and separated from the main lumen with a cross-sectional area approximately fifteen percent of that of the main lumen. The distal end of the tubular member is tapered with the distal end of the secondary lumen closed. The secondary lumen has a side port near the tapered distal end. The sheath also includes a hub with main and secondary passages communicating with the main and secondary lumens of the tubular member. The longitudinal axes of the main passages are substantially parallel to one another. The secondary passage extends laterally from the secondary lumen of the tubular member which is recessed from the proximal end thereof. The hub also includes a third passage communicating with and extending laterally from the main lumen of the tubular member.

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