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1. 发明申请

US20050043788A1 Drug-eluting stent 审中-公开
标题翻译：药物洗脱支架
公开(公告)号：US20050043788A1
公开(公告)日：2005-02-24
申请号：US10943636
申请日：2004-09-17
申请人： Qiyi Luo , Yi Zhang , Zhirong Tang , Heng Zhao , Junfei Ll
发明人： Qiyi Luo , Yi Zhang , Zhirong Tang , Heng Zhao , Junfei Ll
IPC分类号： A61K9/00 , A61F2/00 , A61F2/06 , A61F2/84 , A61K31/165 , A61K31/337 , A61K31/343 , A61K31/427 , A61K31/436 , A61K31/4365 , A61K31/4465 , A61K31/4709 , A61K31/505 , A61K31/52 , A61K31/565 , A61K31/616 , A61K31/704 , A61K31/727 , A61K35/74 , A61K35/76 , A61K38/00 , A61K45/00 , A61K48/00 , A61L27/00 , A61L31/00 , A61P5/00 , A61P7/02 , A61P9/10 , A61P35/00 , A61P37/06
CPC分类号： A61L31/10 , A61F2/07 , A61F2002/075 , A61F2250/0067 , A61L31/048 , A61L31/16 , A61L2300/416 , A61L2300/61 , C08L27/12
摘要： The invention relates to a drug eluting stent and a method for making the stent. The stent comprises a stent body and coats covering on the stent body, it is characterized in that: 2-4 coats are provided on the surface of the stent body, wherein at least two coats are drug coats. The drug coats comprise 0.5-99% polymer by weight, 0-10% additive by weight and 0.5-99% active ingredient by weight. A primer layer is provided between the drug coats and the stent body. A compact control-releasing layer is also coated on the surface of the drug coats.
摘要翻译：本发明涉及药物洗脱支架和制造支架的方法。支架包括支架主体和覆盖在支架主体上的外套，其特征在于：在支架主体的表面上设置2-4个涂层，其中至少两个涂层是药物涂层。药物涂层包含0.5-99重量％的聚合物，0-10重量％的添加剂和0.5-99重量％的活性成分。在药物涂层和支架体之间设置底漆层。一个紧凑的控制释放层也涂在药物外套的表面上。

2. 发明授权

US08734350B2 System and method for correcting errors in shear wave measurements arising from ultrasound beam geometry 有权
标题翻译：用于校正由超声波束几何产生的剪切波测量误差的系统和方法
公开(公告)号：US08734350B2
公开(公告)日：2014-05-27
申请号：US13410780
申请日：2012-03-02
申请人： James F Greenleaf , Shigao Chen , Heng Zhao
发明人： James F Greenleaf , Shigao Chen , Heng Zhao
IPC分类号： A61B8/00
CPC分类号： A61B6/5217 , A61B8/485 , A61B8/587 , G01S7/52022 , G01S7/52042 , G01S7/5205
摘要： A system and method for measuring mechanical properties of a tissue using an ultrasound system is provided. Ultrasound energy is applied to the tissue using the ultrasound system in order to produce shear waves that propagate in the tissue. Measurement data are then acquired by directing ultrasound detection pulses into the tissue. Information about the intensity field of the ultrasound energy used to produce the shear waves is obtained and used to produce a correction factor. This correction factor is applied to the measurement data to correct the measurement data for errors arising from the geometry of the ultrasound energy used to produce the shear waves. From the corrected measurement data, mechanical properties of the tissue are calculated.
摘要翻译：提供了一种使用超声波系统测量组织的机械特性的系统和方法。使用超声系统将超声能量施加到组织，以产生在组织中传播的剪切波。然后通过将超声检测脉冲引导到组织中来获取测量数据。获得关于用于产生剪切波的超声能量的强度场的信息，并用于产生校正因子。该校正因子被应用于测量数据，以校正由用于产生剪切波的超声能量的几何形状引起的误差的测量数据。从校正的测量数据中，计算组织的机械性能。

3. 发明申请

US20120226158A1 System and Method for Correcting Errors in Shear Wave Measurements Arising From Ultrasound Beam Geometry 有权
标题翻译：用于校正来自超声波束几何的剪切波测量中的误差的系统和方法
公开(公告)号：US20120226158A1
公开(公告)日：2012-09-06
申请号：US13410780
申请日：2012-03-02
申请人： James F. Greenleaf , Shigao Chen , Heng Zhao
发明人： James F. Greenleaf , Shigao Chen , Heng Zhao
IPC分类号： A61B8/00
CPC分类号： A61B6/5217 , A61B8/485 , A61B8/587 , G01S7/52022 , G01S7/52042 , G01S7/5205
摘要： A system and method for measuring mechanical properties of a tissue using an ultrasound system is provided. Ultrasound energy is applied to the tissue using the ultrasound system in order to produce shear waves that propagate in the tissue. Measurement data are then acquired by directing ultrasound detection pulses into the tissue. Information about the intensity field of the ultrasound energy used to produce the shear waves is obtained and used to produce a correction factor. This correction factor is applied to the measurement data to correct the measurement data for errors arising from the geometry of the ultrasound energy used to produce the shear waves. From the corrected measurement data, mechanical properties of the tissue are calculated.
摘要翻译：提供了一种使用超声波系统测量组织的机械特性的系统和方法。使用超声系统将超声能量施加到组织，以产生在组织中传播的剪切波。然后通过将超声检测脉冲引导到组织中来获取测量数据。获得关于用于产生剪切波的超声能量的强度场的信息，并用于产生校正因子。该校正因子被应用于测量数据，以校正由用于产生剪切波的超声能量的几何形状引起的误差的测量数据。从校正的测量数据中，计算组织的机械性能。

4. 发明授权

US10624609B2 System and method for shear wave elastography by transmitting ultrasound with subgroups of ultrasound transducer elements 有权
公开(公告)号：US10624609B2
公开(公告)日：2020-04-21
申请号：US14397395
申请日：2013-10-07
申请人： James F. Greenleaf , Shigao Chen , Pengfei Song , Heng Zhao
发明人： James F. Greenleaf , Shigao Chen , Pengfei Song , Heng Zhao
IPC分类号： A61B8/08 , A61B8/00 , G01S7/52 , G01N29/07 , G01N29/26 , G01S15/89
CPC分类号： A61B8/485 , A61B8/08 , A61B8/4488 , A61B8/4494 , A61B8/5223 , G01N29/07 , G01N29/262 , G01S7/5209 , G01S7/52022 , G01S7/52042 , G01S15/8915 , G01S15/8927 , G01N2291/011 , G01N2291/02475 , G01N2291/02827 , G01N2291/0422
摘要： Systems and methods for performing shear wave elastography using push and/or detection ultrasound beams that are generated by subsets of the available number of transducer elements in an ultrasound transducer. These techniques provide several advantages over currently available approaches to shear wave elastography, including the ability to use a standard, low frame rate ultrasound imaging system and the ability to measure shear wave speed throughout the entire field-of-view rather than only those regions where the push beams are not generated.

5. 发明授权

US10034647B2 System and method for endoscopic X-ray luminescence computed tomographic imaging 有权
公开(公告)号：US10034647B2
公开(公告)日：2018-07-31
申请号：US14379732
申请日：2012-03-16
申请人： Jimin Liang , Xueli Chen , Xiaochao Qu , Shouping Zhu , Duofang Chen , Heng Zhao , Jie Tian
发明人： Jimin Liang , Xueli Chen , Xiaochao Qu , Shouping Zhu , Duofang Chen , Heng Zhao , Jie Tian
IPC分类号： A61B6/00 , A61B6/12 , A61B5/00 , A61B6/03
CPC分类号： A61B6/5247 , A61B5/0086 , A61B6/032 , A61B6/12 , A61B6/485
摘要： A system for the endoscopic X-ray luminescence computed tomographic imaging is provided. The system comprises an excitation source unit (1) configured to excite a probe inside a detecting object from an external excitation source; a signal collecting unit (2) configured to collect X-ray images of the detecting object and near-infrared light signal images emitting from the probe being excitated; a computing unit (4) configured to preprocess the collected X-ray images and the near-infrared light signal images, execute sparse reconstruction on the preprocessed X-ray images so as to obtain anatomical structure information of the detecting object and location information of an endoscopic detector in the signal collecting unit (2) inside the detecting object, and use the obtained anatomical structure information and the location information to execute three-dimensional optical reconstruction based on the preprocessed near-infrared light signal images so as to obtain localization and distribution of an imaging target inside the detecting object.

6. 发明申请

US20150119700A1 SYSTEM AND METHOD FOR ENDOSCOPIC X-RAY LUMINESCENCE COMPUTED TOMOGRAPHIC IMAGING 审中-公开
标题翻译：内镜X射线发光计算机图像成像系统与方法
公开(公告)号：US20150119700A1
公开(公告)日：2015-04-30
申请号：US14379732
申请日：2012-03-16
申请人： Jimin Liang , Xueli Chen , Xiaochao Qu , Shouping Zhu , Duofang Chen , Heng Zhao , Jie Tian
发明人： Jimin Liang , Xueli Chen , Xiaochao Qu , Shouping Zhu , Duofang Chen , Heng Zhao , Jie Tian
IPC分类号： A61B6/00 , A61B5/00 , A61B6/12 , A61B6/03
CPC分类号： A61B6/5247 , A61B5/0086 , A61B6/032 , A61B6/12 , A61B6/485
摘要： A system for the endoscopic X-ray luminescence computed tomographic imaging is provided. The system comprises an excitation source unit (1) configured to excite a probe inside a detecting object from an external excitation source; a signal collecting unit (2) configured to collect X-ray images of the detecting object and near-infrared light signal images emitting from the probe being excitated; a computing unit (4) configured to preprocess the collected X-ray images and the near-infrared light signal images, execute sparse reconstruction on the preprocessed X-ray images so as to obtain anatomical structure information of the detecting object and location information of an endoscopic detector in the signal collecting unit (2) inside the detecting object, and use the obtained anatomical structure information and is the location information to execute three-dimensional optical reconstruction based on the preprocessed near-infrared light signal images so as to obtain localization and distribution of an imaging target inside the detecting object.
摘要翻译：提供了一种内镜X射线发光计算机断层成像系统。该系统包括激励源单元（1），其被配置为从外部激励源将检测对象内的探头激发; 信号收集单元（2），被配置为收集检测对象的X射线图像和从被激发的探针发射的近红外光信号图像; 计算单元（4），被配置为对所收集的X射线图像和近红外光信号图像进行预处理，对预处理的X射线图像执行稀疏重建，以获得检测对象的解剖结构信息和位置信息在检测对象内部的信号采集单元（2）中的内窥镜检测器，并使用获得的解剖结构信息，并且是基于预处理的近红外光信号图像执行三维光学重建的位置信息，以获得定位和成像目标在检测对象内的分布。

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