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    • 2. 发明授权
    • GMR biosensor with enhanced sensitivity
    • GMR生物传感器具有增强的灵敏度
    • US08133439B2
    • 2012-03-13
    • US11497162
    • 2006-08-01
    • Po-Kang WangXizeng ShiChyu-Jiuh Torng
    • Po-Kang WangXizeng ShiChyu-Jiuh Torng
    • G01N15/06
    • G01R33/0052B82Y25/00G01N15/0656G01N27/745G01N2015/0065G01R33/05G01R33/093G01R33/098Y10T29/49124Y10T29/49986
    • A sensor array comprising a series connection of parallel GMR sensor stripes provides a sensitive mechanism for detecting the presence of magnetized particles bonded to biological molecules that are affixed to a substrate. The adverse effect of hysteresis on the maintenance of a stable bias point for the magnetic moment of the sensor free layer is eliminated by a combination of biasing the sensor along its longitudinal direction rather than the usual transverse direction and by using the overcoat stress and magnetostriction of magnetic layers to create a compensatory transverse magnetic anisotropy. By making the spaces between the stripes narrower than the dimension of the magnetized particle and by making the width of the stripes equal to the dimension of the particle, the sensitivity of the sensor array is enhanced.
    • 包括并联GMR传感器条的串联连接的传感器阵列提供了用于检测粘附到固定到基底上的生物分子的磁化颗粒的存在的敏感机制。 通过将传感器沿着其纵向方向而不是通常的横向偏置并通过使用传感器的外涂层应力和磁致伸缩的组合来消除滞后对维持传感器自由层的磁矩的稳定偏置点的不利影响 磁性层产生补偿横向磁各向异性。 通过使条纹之间的空间比磁化粒子的尺寸窄,并且通过使条纹的宽度等于粒子的尺寸,传感器阵列的灵敏度增强。