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    • 1. 发明申请
    • NOVEL HETEROCYCLIC DERIVATIVES AND THEIR USES
    • 新型杂环衍生物及其用途
    • US20140315888A1
    • 2014-10-23
    • US14347950
    • 2012-09-28
    • Pil Su HoDong Oh YoonSun Young HanWon Il LeeJung Sook KimWoul Seong ParkSung Oh AhnHye Jung Kim
    • Pil Su HoDong Oh YoonSun Young HanWon Il LeeJung Sook KimWoul Seong ParkSung Oh AhnHye Jung Kim
    • C07D471/14
    • C07D471/14C07D487/14C07D498/14C07D519/00
    • The present invention relates to novel heterocyclic compounds useful in preparing drugs for treatment of diseases associated with various functions of the histamine 4 receptor. Especially, the said drugs are useful for treatment of inflammatory diseases, allergy, pain, nasal polyps, rhinitis, chronic sinusitis, nasal congestion, nasal itch, asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, atopic dermatitis, psoriasis, eczema, pruritus, itchy skin, urticaria, idiopathic chronic urticaria, scleroderma, conjunctivitis, keratoconjunctivitis, ocular inflammation, dry eye, cardiac dysfunction, arrhythmia, atherosclerosis, multiple sclerosis, inflammatory bowel disease (including colitis, Crohn's disease, ulcerative colitis), inflammatory pain, neuropathic pain, osteoarthritic pain, autoimmune thyroid disease, immune-mediated (also known as type I) diabetes, lupus, post-operative adhesions, vestibular disorders and cancer.
    • 本发明涉及可用于制备用于治疗与组胺4受体的各种功能相关的疾病的药物的新型杂环化合物。 特别地,所述药物可用于治疗炎性疾病,过敏,疼痛,鼻息肉,鼻炎,慢性鼻窦炎,鼻塞,鼻痒,哮喘,慢性阻塞性肺病,类风湿性关节炎,特应性皮炎,牛皮癣,湿疹,瘙痒, 瘙痒皮肤,荨麻疹,特发性慢性荨麻疹,硬皮病,结膜炎,角膜结膜炎,眼部炎症,干眼症,心脏功能障碍,心律失常,动脉粥样硬化,多发性硬化,炎性肠病(包括结肠炎,克罗恩病,溃疡性结肠炎),炎性疼痛,神经性疼痛 ,骨关节炎,自身免疫性甲状腺疾病,免疫介导(也称为I型)糖尿病,狼疮,术后粘连,前庭障碍和癌症。
    • 4. 发明授权
    • Time synchronization method in wireless sensor network
    • 无线传感器网络中的时间同步方法
    • US08571008B2
    • 2013-10-29
    • US12743310
    • 2008-06-12
    • Kyeong Tae KimByung Tae JangJeong Dan ChoiDo Hyun KimJae Jun YooKyung Bok SungJung Sook KimJae Han LimJeong Ah Jang
    • Kyeong Tae KimByung Tae JangJeong Dan ChoiDo Hyun KimJae Jun YooKyung Bok SungJung Sook KimJae Han LimJeong Ah Jang
    • H04J3/06
    • H04J3/0667H04J3/0673H04W12/12H04W84/18
    • The present invention relates to a time synchronization method in a wireless sensor network. In the present invention, if an upper node requests a lower reference node to start time synchronization, the lower reference node broadcasts a first sync reference packet. The upper node receives the first sync reference packet and transmits the first sync reference packet reception time to the lower reference node. The lower reference node broadcasts the first sync reference packet reception time, such that the other nodes perform time synchronization on the basis of the first sync reference packet reception time. Meanwhile, the lower reference node estimates the first sync reference packet reception time of the upper node to calculate the reception estimation time, and transmits the reception estimation time to a determination node that is two hops anterior to the lower reference node. Therefore, the determination node compares the reception time received from the upper node and the reception estimation time received from the lower reference node and determines whether a capture attack on the upper node has occurred.
    • 本发明涉及无线传感器网络中的时间同步方法。 在本发明中,如果上层节点请求较低参考节点开始时间同步,则下参考节点广播第一同步参考分组。 上级节点接收第一同步参考分组,并将第一同步参考分组接收时间发送到下参考节点。 下参考节点广播第一同步参考分组接收时间,使得其他节点基于第一同步参考分组接收时间执行时间同步。 同时,下参考节点估计上级节点的第一同步参考分组接收时间以计算接收估计时间,并且将接收估计时间发送到作为下参考节点之前的两跳的确定节点。 因此,确定节点比较从上层节点接收到的接收时间和从较低参考节点接收的接收估计时间,并确定是否发生了对上层节点的捕获攻击。
    • 7. 发明申请
    • TIME SYNCHRONIZATION METHOD IN WIRELESS SENSOR NETWORK
    • 无线传感器网络中的时间同步方法
    • US20100260167A1
    • 2010-10-14
    • US12743310
    • 2008-06-12
    • Kyeong Tae KimByung Tae JangJeong Dan ChoiDo Hyun KimJae Jun YooKyung Bok SungJung Sook KimJae Han LimJeong Ah Jang
    • Kyeong Tae KimByung Tae JangJeong Dan ChoiDo Hyun KimJae Jun YooKyung Bok SungJung Sook KimJae Han LimJeong Ah Jang
    • H04W56/00
    • H04J3/0667H04J3/0673H04W12/12H04W84/18
    • The present invention relates to a time synchronization method in a wireless sensor network. In the present invention, if an upper node requests a lower reference node to start time synchronization, the lower reference node broadcasts a first sync reference packet. The upper node receives the first sync reference packet and transmits the first sync reference packet reception time to the lower reference node. The lower reference node broadcasts the first sync reference packet reception time, such that the other nodes perform time synchronization on the basis of the first sync reference packet reception time. Meanwhile, the lower reference node estimates the first sync reference packet reception time of the upper node to calculate the reception estimation time, and transmits the reception estimation time to a determination node that is two hops anterior to the lower reference node. Therefore, the determination node compares the reception time received from the upper node and the reception estimation time received from the lower reference node and determines whether a capture attack on the upper node has occurred.
    • 本发明涉及无线传感器网络中的时间同步方法。 在本发明中,如果上层节点请求较低参考节点开始时间同步,则下参考节点广播第一同步参考分组。 上级节点接收第一同步参考分组,并将第一同步参考分组接收时间发送到下参考节点。 下参考节点广播第一同步参考分组接收时间,使得其他节点基于第一同步参考分组接收时间执行时间同步。 同时,下参考节点估计上级节点的第一同步参考分组接收时间以计算接收估计时间,并且将接收估计时间发送到作为下参考节点之前的两跳的确定节点。 因此,确定节点比较从上层节点接收到的接收时间和从较低参考节点接收的接收估计时间,并确定是否发生了对上层节点的捕获攻击。