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1. 发明申请

US20070027133A1 BICYCLIC PYRAZOLYL AND IMIDAZOLYL COMPOUNDS AND USES THEREOF 审中-公开
标题翻译：双丙基吡唑并咪唑化合物及其用途
公开(公告)号：US20070027133A1
公开(公告)日：2007-02-01
申请号：US11470695
申请日：2006-09-07
申请人： Philip Carpino , Robert Dow , David Griffith
发明人： Philip Carpino , Robert Dow , David Griffith
IPC分类号： A61K31/554 , A61K31/553 , A61K31/5513 , A61K31/55 , C07D487/02 , C07D491/02 , C07D498/02
CPC分类号： C07D487/14 , C07D471/04 , C07D487/04 , C07D513/04
摘要： Compounds of Formula (I) are described herein. The compounds have been shown to act as cannabinoid receptor ligands and are therefore useful in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals.
摘要翻译：式（I）化合物在本文中描述。已经显示这些化合物作为大麻素受体配体，因此可用于治疗与动物中的大麻素受体的介导相关的疾病。

2. 发明申请

US20050101592A1 Bicyclic pyrazolyl and imidazolyl compounds and uses thereof 失效
标题翻译：双环吡唑基和咪唑基化合物及其用途
公开(公告)号：US20050101592A1
公开(公告)日：2005-05-12
申请号：US10971599
申请日：2004-10-22
申请人： Philip Carpino , Robert Dow , David Griffith
发明人： Philip Carpino , Robert Dow , David Griffith
IPC分类号： A61K31/55 , A61K31/551 , A61K31/553 , A61K31/554 , C07D471/04 , C07D487/04 , C07D487/14 , C07D491/02 , C07D498/02 , C07D498/04 , C07D513/04
CPC分类号： C07D487/14 , C07D471/04 , C07D487/04 , C07D513/04
摘要： Compounds of Formula (I) are described herein. The compounds have been shown to act as cannabinoid receptor ligands and are therefore useful in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals.
摘要翻译：式（I）化合物在本文中描述。已经显示这些化合物作为大麻素受体配体，因此可用于治疗与动物中的大麻素受体的介导相关的疾病。

3. 发明申请

US20070105856A1 CANNABINOID RECEPTOR LIGANDS AND USES THEREOF 失效
公开(公告)号：US20070105856A1
公开(公告)日：2007-05-10
申请号：US11538498
申请日：2006-10-04
申请人： Philip Carpino , David Griffith
发明人： Philip Carpino , David Griffith
IPC分类号： A61K31/5377 , A61K31/4745 , C07D471/02
CPC分类号： C07D471/04 , C07D487/04
摘要： Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein.

4. 发明授权

US09074819B2 High velocity fluid flow electric heater 有权
标题翻译：高速流体流动电加热器
公开(公告)号：US09074819B2
公开(公告)日：2015-07-07
申请号：US13439543
申请日：2012-04-04
申请人： Craig S. Tiras , David Griffith
发明人： Craig S. Tiras , David Griffith
IPC分类号： F27D11/00 , F27D11/02
CPC分类号： F27D11/02
摘要： An electrical heater has first and second heater elements, each having a hairpin-shaped metal tube with an upstream and a downstream leg and tube ends adjacent each other. An electrical resistance wire surrounded by insulation powder extends through the tube. Electrical terminals join to the wire and protrude from each of the tube ends. Conduits enclose the upstream and the downstream legs of the heater elements, providing a continuous annular flow path. A manifold has heater element passages for end portion of the legs. An inlet passage in the manifold leads from an exterior portion of the manifold to the annular flow path surrounding the upstream leg of the first heater element. A transfer passage within the manifold leads from the annular flow path surrounding the downstream leg of the first heater element to the annular flow path surrounding the upstream leg of the second heater element.
摘要翻译：电加热器具有第一和第二加热器元件，每个具有发夹形金属管，其具有上游和下游腿以及管彼此相邻的端部。由绝缘粉末包围的电阻丝穿过管延伸。电端子连接到电线并从每个管端突出。管道包围加热器元件的上游和下游腿部，提供连续的环形流动路径。歧管具有用于腿的端部的加热器元件通道。歧管中的入口通道从歧管的外部部分引导到围绕第一加热器元件的上游支腿的环形流动路径。歧管内的传送通道从包围第一加热器元件的下游腿部的环形流动路径引导到围绕第二加热器元件的上游支腿的环形流动路径。

5. 发明申请

US20080132457A1 BACTERIAL EFFLUX PUMP INHIBITORS FOR THE TREATMENT OF OPHTHALMIC AND OTIC INFECTIONS 失效
标题翻译：用于治疗眼睛和眼睛感染的细菌液体泵抑制剂
公开(公告)号：US20080132457A1
公开(公告)日：2008-06-05
申请号：US11856657
申请日：2007-09-17
申请人： Keith Bostian , Thomasz Glinka , Olga Lomovskaya , Mark Surber , Neil Berkley , David Griffith
发明人： Keith Bostian , Thomasz Glinka , Olga Lomovskaya , Mark Surber , Neil Berkley , David Griffith
IPC分类号： A61K31/7048 , A61K31/155 , A61K31/655 , A61K31/17 , A61K31/4709 , A61K31/4375 , A61K31/546 , A61K31/496 , A61K31/7036 , A61P31/04 , A61K31/5383
CPC分类号： A61K31/155 , A61K31/17 , A61K31/4375 , A61K31/4709 , A61K31/496 , A61K31/5383 , A61K31/546 , A61K31/655 , A61K31/7036 , A61K45/06 , Y02A50/401 , Y02A50/47 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481 , Y02A50/483 , A61K2300/00
摘要： Efflux pump inhibitors are co-administered with antimicrobial agents for the treatment of ophthalmic or otic infections. The agents may be co-administered directly to the site of infection (e.g., the eye or ear).
摘要翻译：流出泵抑制剂与抗微生物剂共同给药以治疗眼部或耳部感染。药剂可以直接共同施用于感染部位（例如眼睛或耳朵）。

6. 发明申请

US20060253039A1 Anastomotic ring applier with inflatable members 有权
标题翻译：具有充气构件的吻合环施加器
公开(公告)号：US20060253039A1
公开(公告)日：2006-11-09
申请号：US11122761
申请日：2005-05-05
申请人： Robert McKenna , Mark Ortiz , David Griffith , Robert Simms
发明人： Robert McKenna , Mark Ortiz , David Griffith , Robert Simms
IPC分类号： A61B5/02
CPC分类号： A61B17/1114 , A61B17/08 , A61B17/115 , A61B17/12045 , A61B17/12136 , A61B17/3474 , A61B2017/00367 , A61B2017/00867 , A61B2017/0408 , A61B2017/1135 , A61B2017/12127 , A61B2017/22054
摘要： A surgical instrument comprises a handle connected to a shaft and a pair of inflatable members. The shaft includes conduits for communicating a pressurized medium to the inflatable members and an insufflation tube. The handle includes a port for communicating a pressurized medium to the conduits and a port for communicating a pressurized medium to the insufflation tube. After an anastomotic ring has been deployed, the shaft may be positioned such that an inflatable member is positioned within each of the lumens joined by the anastomosis, such that an inflatable member is located on each side of the anastomosis. The inflatable members may be inflated to provide a seal in each of the lumens. With each of the lumens sealed by the inflatable members, the anastomosis site may be insufflated through the insufflation tube to leak or pressure test the anastomosis.
摘要翻译：手术器械包括连接到轴的手柄和一对可充气构件。轴包括用于将加压介质连通到可膨胀构件的管道和吹入管。手柄包括用于将加压介质传送到导管的端口和用于将加压介质连通到吹入管的端口。在已经部署了吻合口环之后，轴可以被定位成使得可膨胀构件定位在通过吻合连接的每个腔内，使得可充气构件位于吻合的每一侧。可膨胀构件可以被充气以在每个管腔中提供密封。通过由可膨胀构件密封的每个管腔，吻合部位可以通过吹气管吹入以泄漏或压力测试吻合。

7. 发明申请

US20050165178A1 Continuous process for producing poly (trimethylene terephthalate) 有权
标题翻译：生产聚对苯二甲酸丙二醇酯的连续工艺
公开(公告)号：US20050165178A1
公开(公告)日：2005-07-28
申请号：US11093092
申请日：2005-03-29
申请人： Carl Giardino , David Griffith , Chungfan Ho , James Howell , Michelle Watkins
发明人： Carl Giardino , David Griffith , Chungfan Ho , James Howell , Michelle Watkins
IPC分类号： C08F2/00 , C08G63/183 , C08G63/78 , C08G85/00
CPC分类号： C08G63/183 , C08G63/78 , Y10T428/2913 , Y10T428/31786
摘要： A continuous process for the production of poly(trimethylene terephthalate) is disclosed. According to the process, a liquid feed mixture comprising bis-3-hydroxypropyl terephthalate and/or low molecular weight polyesters of 1,3-propanediol and terephthalic acid, the liquid feed mixture having a mole ratio of propylene groups to terephthalate groups of 1.1 to 2.2 is fed to a flasher. A first stream of gaseous by-products is continuously vaporized and removed from the flasher, and a liquid flasher reaction product having a mole ratio of propylene groups to terephthalate groups of less than about 1.5 is continuously withdrawn from the flasher. The liquid flasher reaction product is continuously fed to a prepolymerizer where it is continuously polymerized to form a poly(trimethylene terephthalate) prepolymer and a second stream of gaseous by-products. Poly(trimethylene terephthalate) prepolymer having a relative viscosity of at least about 5 is continuously withdrawn from the prepolymerizer and continuously fed to a final polymerizer, where it is continuously polymerized to form a higher molecular weight poly(trimethylene terephthalate) and a third stream of gaseous by-products. Higher molecular weight poly(trimethylene terephthalate) having a relative viscosity of at least about 17 is continuously withdrawn from the final polymerizer.
摘要翻译：公开了生产聚（对苯二甲酸丙二醇酯）的连续方法。根据该方法，将包含1,3-丙二醇和对苯二甲酸的低分子量聚酯的双-3-羟丙基对苯二甲酸酯和/或低分子量聚酯的液体进料混合物，该丙烯与对苯二甲酸酯基的摩尔比为1.1〜 2.2被送入闪光器。气态副产物的第一流被持续蒸发并从闪蒸器中除去，并且具有小于约1.5的丙烯与对苯二甲酸酯基的摩尔比的液体闪蒸反应产物从闪蒸器中连续排出。将液体闪蒸反应产物连续进料到预聚合器中，在其中连续聚合以形成聚（对苯二甲酸丙二醇酯）预聚物和第二气态副产物流。相对粘度至少为约5的聚（对苯二甲酸丙二醇酯）预聚物从预聚合器中连续排出，并连续进料至最终聚合反应器，在其中连续聚合形成较高分子量的聚对苯二甲酸丙二醇酯气态副产品。相对粘度至少约为17的较高分子量聚（对苯二甲酸丙二醇酯）从最终聚合反应器中连续排出。

8. 发明授权

US09402773B2 Prone cart 有权
标题翻译：自由车
公开(公告)号：US09402773B2
公开(公告)日：2016-08-02
申请号：US14603958
申请日：2015-01-23
申请人： Lynda Woodman , Gary J. Kroll , Karen Cepress , Amy Schulz , Kath Roske , Paula Braaten , David Griffith
发明人： Lynda Woodman , Gary J. Kroll , Karen Cepress , Amy Schulz , Kath Roske , Paula Braaten , David Griffith
IPC分类号： B62B5/00 , A61G1/044 , A61G1/04 , A61G1/013 , A61G1/02 , A61G1/048 , A61G5/02
CPC分类号： A61G1/044 , A61G1/013 , A61G1/0212 , A61G1/0237 , A61G1/0287 , A61G1/04 , A61G1/048 , A61G5/02 , A61G2200/325
摘要： A prone cart for transporting a patient in a hospital or clinic setting is provided. The prone cart includes a frame having a pair of extension slides coupled thereto and first and second sets of wheels. An upper portion includes first and second moveably adjustable trays operably coupled to said extension slides. The second tray includes a plurality of apertures in at least one side rail and the first tray includes at least one locking spring pin operably receivable by one of said plurality of apertures. The prone cart also includes a patient support surface.
摘要翻译：提供了一种用于在医院或诊所设置中运送病人的俯卧车。俯卧车包括一个框架，该框架具有一对连接到其上的延伸滑动件以及第一和第二组轮子。上部包括可操作地联接到所述延伸滑块的第一和第二可移动调节的托盘。第二托盘包括在至少一个侧轨中的多个孔，并且第一托盘包括可操作地由所述多个孔之一接收的至少一个锁定弹簧销。倾斜车还包括患者支撑表面。

9. 发明授权

US08780543B2 Integrated feature for friction-less movement of force sensitive touch screen 有权
标题翻译：功能强大的触摸屏无摩擦移动的综合功能
公开(公告)号：US08780543B2
公开(公告)日：2014-07-15
申请号：US13425846
申请日：2012-03-21
申请人： Anders L. Mölne , David Griffith , Mark Lackey , Curtiss Noble
发明人： Anders L. Mölne , David Griffith , Mark Lackey , Curtiss Noble
IPC分类号： G06F1/16 , H05K5/00 , H05K7/00
CPC分类号： G06F3/0414 , G02F1/13338 , G02F1/133526 , G06F1/1656
摘要： A suspension system for a differential-pressure touch sensitive panel suspended over force sensors, for use in either fixed or mobile devices such as point of sales terminals, kiosks, laptops, monitors, PDAs, cell phones, UMPCs and more. In one embodiment, a number of leaf springs are attached directly to the touch lens at both ends and attached directly to the underlying housing at the center, effectively pulling the leaf spring down at the center into a concave arc. The spring bias preloads the touch lens downward against the force sensors. The leaf springs bring the touch lens into a fixed state in the xy-plane and resist translation; however, the touch lens remains free to float against the bias of the leaf spring(s) without any frictional physical contact along the z-axis.
摘要翻译：一种悬挂在力传感器上的差压触摸屏的悬挂系统，用于固定或移动设备，如销售点终端，售货亭，笔记本电脑，显示器，PDA，手机，UMPC等。在一个实施例中，多个板簧在两端直接附接到触摸透镜，并且在中心直接附着在下面的壳体上，有效地将板簧在中心向下拉成凹弧。弹簧偏压使触摸透镜向下抵抗力传感器。板簧使触摸透镜在xy平面处于固定状态并抵抗平移; 然而，触摸透镜保持自由地抵抗板簧的偏压而浮动，而不沿着z轴的任何摩擦物理接触。

10. 发明授权

US08270148B2 Suspension for a pressure sensitive touch display or panel 有权
标题翻译：用于压敏触摸显示器或面板的悬架
公开(公告)号：US08270148B2
公开(公告)日：2012-09-18
申请号：US12831772
申请日：2010-07-07
申请人： David Griffith , Gary Smith , Mark Lackey , Anders Mölne
发明人： David Griffith , Gary Smith , Mark Lackey , Anders Mölne
IPC分类号： G06F1/16
CPC分类号： G06F3/0414 , G06F3/03547 , H01H9/025 , H01H2219/024
摘要： A suspension system for mounting a touch surface of a pressure sensitive touch display or panel. The suspension system comprises a frame and a flexible suspension membrane connected to the touch surface and the frame, the membrane allowing frictionless movement of the touch surface along the z-axis and resisting movement of the touch surface within the x-y plane. At least one force sensor is connected beneath the touch surface, whereby the touch surface is pre-loaded against the at least one force sensor.
摘要翻译：一种用于安装压敏触摸显示器或面板的触摸表面的悬挂系统。悬挂系统包括框架和连接到触摸表面和框架的柔性悬挂膜，该膜允许触摸表面沿z轴无摩擦移动并抵抗触摸表面在x-y平面内的移动。至少一个力传感器连接在触摸表面下方，由此触摸表面被预先加载到至少一个力传感器上。

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