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1. 发明授权

US5819508A Device for removing or twisting off caps from vessels 失效
标题翻译：用于从船只移除或扭转帽子的装置
公开(公告)号：US5819508A
公开(公告)日：1998-10-13
申请号：US627620
申请日：1996-04-04
申请人： Peter Kraft , Horst Menzler , Hans Schels , Peter Wenzig
发明人： Peter Kraft , Horst Menzler , Hans Schels , Peter Wenzig
IPC分类号： B67B7/02 , B67B7/18 , B67B7/14
CPC分类号： B67B7/182 , B67B7/02
摘要： Device for pulling out or twisting off caps from vessels, wherein the vessel is held, and the cap is removed by means of a cap-holding device; the cap-holding device executes both a linear movement in direction of the vessel axis as well as a rotating movement around the vessel axis. The cap-holding device advantageously has several clamping jaws that are pressed against the circumference of the cap.
摘要翻译：用于从容器中拉出或扭转帽的装置，其中容器被保持，并且帽通过盖保持装置移除; 盖保持装置在容器轴线的方向上执行线性运动以及围绕容器轴线的旋转运动。盖保持装置有利地具有几个压靠在盖的圆周上的夹爪。

2. 发明授权

US6107055A Method and device for carrying out biochemical reactions 失效
标题翻译：进行生化反应的方法和装置
公开(公告)号：US6107055A
公开(公告)日：2000-08-22
申请号：US124985
申请日：1998-07-30
申请人： Hermann Bauer , Horst Menzler , Gerd Kleinhammer , Hans Schels , Peter Bendzko , Ute Fink , Bernd Maciej
发明人： Hermann Bauer , Horst Menzler , Gerd Kleinhammer , Hans Schels , Peter Bendzko , Ute Fink , Bernd Maciej
IPC分类号： C12M1/00 , C12M1/12 , C12M1/40 , C12P21/00 , C12P21/06 , C12P1/00
CPC分类号： C12M23/34 , C12M29/04 , C12M29/18
摘要： Method and apparatus for carrying out biochemical reactions in particular for cell-free polypeptide biosynthesis. A bioreactor has, within a housing, a reaction chamber containing a producing system as well as a supply chamber separated from the reaction chamber by means of a semi-permeable membrane and containing a liquid serving as supply medium for the producing system. The supply chamber is subdivided within the bioreactor into a first partial chamber and a second partial chamber which are each connected to the reaction chamber via a semi-permeable supply membrane and which are connected to each other by means of a connection conduit. During the biochemical reaction, liquid is circulated from the first partial chamber of the supply chamber through the reaction chamber and into the second partial chamber of the supply chamber in such a fashion that, during each passage of liquid out of the first partial chamber into the reaction chamber, liquid simultaneously passes from the reaction chamber into the second partial chamber and liquid flows out of the second partial chamber via the connection conduit back into the first partial chamber.
摘要翻译：用于进行生化反应的方法和装置，特别是用于无细胞的多肽生物合成。生物反应器在壳体内具有包含生产系统的反应室以及通过半透膜与反应室分离并且含有用作生产系统的供应介质的液体的供应室。供应室在生物反应器内被分为第一部分室和第二部分室，第一部分室和第二部分室通过半渗透供应膜连接到反应室，并通过连接导管相互连接。在生化反应期间，液体从供给室的第一部分室通过反应室循环，并进入供给室的第二部分室，使得在液体从第一部分室流出之前进入反应室，液体同时从反应室通入第二部分室，并且液体经由连接导管从第二部分室流出回到第一部分室中。

3. 发明授权

US5362147A Method and apparatus for the contactless automatic mixing of a reaction mixture in an analysis unit 失效
标题翻译：用于在分析单元中的非接触式自动混合反应混合物的方法和装置
公开(公告)号：US5362147A
公开(公告)日：1994-11-08
申请号：US123994
申请日：1993-09-21
申请人： Hans Schels , Horst Menzler
发明人： Hans Schels , Horst Menzler
IPC分类号： B01F13/02 , G01N1/36 , G01N35/02
CPC分类号： B01F13/0272
摘要： Method for the contactless automatic mixing of a liquid reaction mixture in an analysis unit, in which the reaction mixture is located in a vessel accessible from above through an opening, by means of a gas jet escaping from an outlet opening of a mixing element, a rapid, effective and reliable non-invasive thorough mixing of the liquid is achieved by the mixing element being lowered at the start of the mixing operation in the direction of the liquid surface and the lowering movement being stopped in a bottom end position in which the mixing element projects into the vessel, but does not touch the liquid surface, the gas jet is switched on during the lowering of the mixing element, the gas jet is so aligned that it brings about an asymmetrical lowering of a part of the liquid surface in the vicinity of the vessel wall, and the gas jet has a rotational component of motion so that the lowered part of the liquid surface is set in rotation about the axis of the vessel.
摘要翻译：在分析单元中非离子自动混合液体反应混合物的方法，其中反应混合物通过从混合元件的出口排出的气体喷射器通过开口位于从上方可接近的容器中，通过混合元件在混合操作开始时在液面的方向上降低液体的快速，有效和可靠的非侵入性彻底混合，并且下降运动停止在下端位置元件投射到容器中，但不接触液体表面，在混合元件降低期间气体射流被接通，气体射流如此对齐，使得气体射流引起液体表面的一部分的不对称降低容器壁附近，气体射流具有运动的旋转分量，使得液面的下降部分围绕容器的轴线旋转。

4. 发明授权

US07156996B2 Multichamber microdialysis device 有权
标题翻译：多室微透析装置
公开(公告)号：US07156996B2
公开(公告)日：2007-01-02
申请号：US10652938
申请日：2003-09-02
申请人： Manfred Watzele , Bernd Buchberger , Hans Schels , Horst Menzler , Ulrike Fischer
发明人： Manfred Watzele , Bernd Buchberger , Hans Schels , Horst Menzler , Ulrike Fischer
IPC分类号： B01D63/00 , C12M1/12 , B01L11/00
CPC分类号： B01D61/28 , B01L3/50255 , B01L3/50855 , B01L2300/0829 , G01N1/405
摘要： The invention is a multichamber microdialysis device with a multitude of sample chambers in close side by side arrangement (similar to a microtiter plate) for receiving liquid samples, and at least one dialysate chamber for receiving a dialysate liquid. The sample chambers are surrounded by circumferential sidewalls and are in liquid exchange contact to a neighboring dialysis chamber via an exchange opening covered by a semipermeable membrane. The semipermeable membrane is fixed liquid-tight to the walls of the sample chamber, so that a diffusion exchange between the sample chamber and the correspondingly neighboring dialysate chamber is only possible via the membrane. Consequently, only molecules with a molecular weight below the molecular cut-off of the semipermeable membrane can diffuse from the sample chamber to the dialysate chamber or from the dialysate chamber to the sample chamber.
摘要翻译：本发明是一种多室微透析装置，其具有用于接收液体样品的紧密并排布置（类似于微量滴定板）的多个样品室和用于接收透析液体的至少一个透析室。样品室被圆周侧壁包围，并通过由半透膜覆盖的交换开口与邻近的透析室液体交换接触。半透膜不透液体地固定在样品室的壁上，使样品室和相应的相邻透析液室之间的扩散交换只能通过膜。因此，只有分子量低于半透膜的分子截止分子的分子可以从样品室扩散到透析液室或从透析液室扩散到样品室。

5. 发明授权

US06670173B1 Bioreaction module for biochemical reactions 失效
标题翻译：用于生化反应的生物反应模块
公开(公告)号：US06670173B1
公开(公告)日：2003-12-30
申请号：US09890090
申请日：2001-07-26
申请人： Hans Schels , Horst Menzler , Ulrike Fischer
发明人： Hans Schels , Horst Menzler , Ulrike Fischer
IPC分类号： C12M112
CPC分类号： C12M23/34 , C12M21/18 , C12M23/38 , C12M29/04 , C12M29/20
摘要： A bioreaction module for biochemical reactions, in particular for cell-free polypeptide biosynthesis, having a housing (1) including a system chamber (12) and a supply chamber (10), wherein the system chamber (12) contains a producing system during the biochemical reaction and the supply chamber (10) contains a supply liquid during the biochemical reaction, and the system chamber (12) and the supply chamber (10) are separated by a semi-permeable membrane (7). The housing (1) comprises a system chamber element (5) and at least one supply chamber element (3) between which the semi-permeable membrane (7) is mounted in such a manner that the system chamber (12) is defined by the system chamber element (5) and the semi-permeable membrane (7) and the supply chamber (10) is defined by the supply chamber element (3) and the semi-permeable membrane (7).
摘要翻译：一种用于生物化学反应，特别是无细胞多肽生物合成的生物反应模块，具有包括系统室（12）和供应室（10）的壳体（1），其中所述系统室（12）包含在生化反应和供给室（10）在生化反应期间含有供液，系统室（12）和供料室（10）由半透膜（7）分开。壳体（1）包括系统室元件（5）和至少一个供应室元件（3），半透膜（7）以这样的方式安装，使得系统室（12）由系统室元件（5）限定，半透膜（7）和供给室（10）由供给室元件（3）和半透膜（7）构成。

6. 外观设计

USD437408S1 Dialyzer 失效
标题翻译：透析器
公开(公告)号：USD437408S1
公开(公告)日：2001-02-06
申请号：US29112844
申请日：1999-10-25
申请人： Horst Menzler , Hans Schels
设计人： Horst Menzler , Hans Schels

7. 发明授权

US5780306A Method and system for mixing liquids 失效
标题翻译：混合液体的方法和系统
公开(公告)号：US5780306A
公开(公告)日：1998-07-14
申请号：US744506
申请日：1996-11-07
申请人： Hans Schels , Karl-Heinz Mann , Horst Menzler , Leonhard Geissler , Georg Kuffer
发明人： Hans Schels , Karl-Heinz Mann , Horst Menzler , Leonhard Geissler , Georg Kuffer
IPC分类号： B01F13/02 , B01F15/00 , G01N1/10
CPC分类号： B01F13/0272 , B01F15/00155 , B01F15/00253 , B01F2215/0037 , Y10T436/119163 , Y10T436/25 , Y10T436/25625
摘要： The invention relates to a system for mixing a liquid with another liquid or a solid material by blowing a gas onto the surface of the liquid. The invention further relates to a system for implementing said method. Gas is blown onto the surface of the liquid from a distance which can be adjusted by determining the level of the liquid. A system of the invention, hence, comprises a device for blowing a gas onto the surface of a liquid and a device for detecting the level of a liquid.
摘要翻译：本发明涉及一种通过将气体吹送到液体表面上而将液体与另一种液体或固体材料混合的系统。本发明还涉及一种用于实现所述方法的系统。气体从一定距离吹到液体表面，该距离可以通过确定液体的液位来调节。因此，本发明的系统包括用于将气体吹送到液体表面上的装置和用于检测液体液位的装置。

8. 发明授权

US5298425A Device for the positionally correct feeding of test strips to an analysis unit 失效
标题翻译：用于将测试条位置正确馈送到分析单元的装置
公开(公告)号：US5298425A
公开(公告)日：1994-03-29
申请号：US15373
申请日：1993-02-09
申请人： Hans-Jurgen Kuhn , Horst Menzler , Stephan Sattler
发明人： Hans-Jurgen Kuhn , Horst Menzler , Stephan Sattler
IPC分类号： B65G47/08 , B65G47/14 , B65G47/78 , B65G47/84 , G01N35/00 , B23Q7/12 , B65H9/00
CPC分类号： G01N35/00029 , B65G47/1407 , G01N2035/00039 , Y10T436/11
摘要： Device for the positionally correct feeding of test strips to an analysis unit. The test strips 10 include a base layer and at least one raised test field fixed to one side of the base layer. The test strips are contained disordered with respect to their longitudinal axis rotation position in a storage container. A separation and position correcting device 1 serves to feed the test strips 10 individually one after the other in a defined position to the analysis unit. Simplicity of construction and reliable operation are achieved due to the fact that the separation and position correcting device 1 includes a position correcting stage 30 with two rolls, between which a narrow gap 35 exists. The rolls rotate so that the surface 31a of the first roll 31 moves in the region of the gap 35 from top to bottom, while the surface 32a of the second roll 32 moves from bottom to top. The first roll 31 includes peripheral raised webs 37 which are in alignment with test field-free regions of the test strips 10. The second roll 32 is provided with axially parallel running drivers 38. The width of the gap 35 in the region of the raised webs 37 is smaller than the thickness of the test strips including the test field.
摘要翻译：用于将测试条位置正确馈送到分析单元的装置。测试条10包括基层和固定到基层一侧的至少一个凸起测试场。测试条相对于其在储存容器中的纵轴旋转位置是无序的。分离和位置校正装置1用于将测试条10一个接一个地单独地送入分析单元。由于分离和位置校正装置1包括具有两个辊的位置校正台30，其间存在狭窄的间隙35，实现了结构简单和操作可靠。辊旋转，使得第一辊31的表面31a在间隙35的区域中从顶部向底部移动，而第二辊32的表面32a从底部移动到顶部。第一辊31包括与测试条10的无测试区域对准的周向凸起腹板37.第二辊32设置有轴向平行的行进驱动器38.间隙35在凸起区域中的宽度网37比包括测试场的测试条的厚度小。

9. 发明授权

US5830413A Device for processing slide-mounted samples 失效
标题翻译：用于处理载玻片样品的装置
公开(公告)号：US5830413A
公开(公告)日：1998-11-03
申请号：US606991
申请日：1996-02-26
申请人： Alfred Lang , Horst Menzler
发明人： Alfred Lang , Horst Menzler
IPC分类号： G01N33/48 , G01N1/28 , G01N1/30 , G01N1/31 , G02B21/34 , B01L3/00 , G01N33/53
CPC分类号： G01N1/312
摘要： A device for processing slides-mounted samples where a slide is urged against a cell block so that a chamber is formed between cell block and slide. Via a fluid channel having a funnel at its one end, the chamber can be filled with liquid by means of a pipetting device having a connecting tip which matches the supply funnel. A device for processing samples where a contact pressure plate serves to press a slide against the cell block of the device. A device for processing samples comprising a down-pressure element which, when in non-operating mode, blocks the device from supplying liquid and where liquid can be supplied when said element is pressed down.
摘要翻译：一种用于处理滑动安装的样品的装置，其中滑块被推靠在电池块上，使得在电池块和滑块之间形成腔室。通过在其一端具有漏斗的流体通道，腔室可以通过具有与供应漏斗匹配的连接尖端的移液装置填充液体。一种用于处理样品的装置，其中接触压板用于将滑块压靠在装置的电池块上。一种用于处理样品的装置，包括下压元件，所述下压元件在非操作模式下阻止所述装置供应液体，并且当所述元件被压下时可以供应液体。

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