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1. 发明授权

US07291824B2 Photosensing throughout energy range and in subranges 有权
标题翻译：在能量范围和子范围内进行光敏感
公开(公告)号：US07291824B2
公开(公告)日：2007-11-06
申请号：US11316438
申请日：2005-12-22
申请人： Peter Kiesel , Oliver Schmidt , Oliver Wolst
发明人： Peter Kiesel , Oliver Schmidt , Oliver Wolst
IPC分类号： G01J3/50
CPC分类号： G01J1/4228 , G01J3/02 , G01J3/0213 , G01J3/26 , G01J3/2803 , G01N21/47 , G01N21/645 , G01N21/65 , G01N2021/4709 , G01N2021/6417 , H01L27/14601 , H01L27/14621
摘要： An integrated circuit (IC) includes a photosensor array, some cells of which are reference cells that photosense throughout an application's energy range, while other cells of which are subrange cells that photosense within respective subranges. For example, the subrange cells can receive photons in their respective subranges from a transmission structure that has laterally varying properties, such as due to varying optical thickness. The reference cells may be uncoated or may also receive photons through a transmission structure such as a gray filter. Subrange cells and reference cells may be paired in adjacent lines across the array, such as rows. Where photon emanation can vary along a path, quantities of incident photons photosensed by subrange cells along the path can be adjusted based on quantities photosensed by their paired reference cells, such as with normalization.
摘要翻译：集成电路（IC）包括光电传感器阵列，其中一些单元是在整个应用的能量范围内照射的参考单元，而其他单元是在相应子范围内的光密度的子范围单元。例如，子范围单元可以从具有横向变化的特性的传输结构接收其各自子范围内的光子，例如由于光学厚度的变化。参考单元可以是未涂覆的，或者也可以通过诸如灰色滤波器的透射结构接收光子。子范围单元格和参考单元可以在阵列中的相邻行中配对，例如行。当光子发射可以沿着路径变化时，可以基于通过其配对参考细胞（例如通过归一化）照射的光量来调整沿着路径由子范围单元照射的入射光子的量。

2. 发明申请

US20070145236A1 Photosensing throughout energy range and in subranges 有权
公开(公告)号：US20070145236A1
公开(公告)日：2007-06-28
申请号：US11316438
申请日：2005-12-22
申请人： Peter Kiesel , Oliver Schmidt , Oliver Wolst
发明人： Peter Kiesel , Oliver Schmidt , Oliver Wolst
IPC分类号： H01L27/00 , G01J1/44
CPC分类号： G01J1/4228 , G01J3/02 , G01J3/0213 , G01J3/26 , G01J3/2803 , G01N21/47 , G01N21/645 , G01N21/65 , G01N2021/4709 , G01N2021/6417 , H01L27/14601 , H01L27/14621
摘要： An integrated circuit (IC) includes a photosensor array, some cells of which are reference cells that photosense throughout an application's energy range, while other cells of which are subrange cells that photosense within respective subranges. For example, the subrange cells can receive photons in their respective subranges from a transmission structure that has laterally varying properties, such as due to varying optical thickness. The reference cells may be uncoated or may also receive photons through a transmission structure such as a gray filter. Subrange cells and reference cells may be paired in adjacent lines across the array, such as rows. Where photon emanation can vary along a path, quantities of incident photons photosensed by subrange cells along the path can be adjusted based on quantities photosensed by their paired reference cells, such as with normalization.

3. 发明申请

US20060039009A1 Chip-size wavelength detector 有权
标题翻译：芯片尺寸波长检测器
公开(公告)号：US20060039009A1
公开(公告)日：2006-02-23
申请号：US10922870
申请日：2004-08-23
申请人： Peter Kiesel , Oliver Schmidt , Oliver Wolst
发明人： Peter Kiesel , Oliver Schmidt , Oliver Wolst
IPC分类号： G01B9/02
CPC分类号： G01J9/0246 , G01J3/26
摘要： A chip-size wavelength detector includes a film with laterally varying transmission properties and a position-sensitive detector. The film transmits a different wavelength as a function of lateral position across the film. The position of a spot of light transmitted through the film will shift, depending on the wavelength of the light. The shift is measured by the position-sensitive detector.
摘要翻译：芯片尺寸波长检测器包括具有横向变化的透射特性的膜和位置敏感检测器。薄膜透过不同的波长作为跨膜的横向位置的函数。透过薄膜的光斑的位置将根据光的波长而移动。位移由位置敏感检测器测量。

4. 发明授权

US07248361B2 Fluorescence reader based on anti-resonant waveguide excitation 有权
标题翻译：基于反谐振波导激发的荧光读数器
公开(公告)号：US07248361B2
公开(公告)日：2007-07-24
申请号：US11315797
申请日：2005-12-22
申请人： Peter Kiesel , Oliver Wolst , Michael Kneissl , Huangpin Ben Hsieh , Oliver Schmidt
发明人： Peter Kiesel , Oliver Wolst , Michael Kneissl , Huangpin Ben Hsieh , Oliver Schmidt
IPC分类号： G01N21/64
CPC分类号： G01N21/645 , G01N21/03 , G01N21/0303 , G01N21/05 , G01N21/31 , G01N21/33 , G01N21/35 , G01N21/3504 , G01N21/3577 , G01N21/3581 , G01N21/59 , G01N21/64 , G01N21/6456 , G01N2021/0346 , G01N2021/058 , G01N2021/513 , G01N2021/6467 , G01N2021/6469 , G01N2021/6493
摘要： A sample detection system including an anti-resonant waveguide, including a sample having a first index of refraction, a top layer and a substrate surrounding the sample, where the top layer has a second index of refraction, and the substrate has a third index of refraction. The second index of refraction, and the third index of refraction are both greater than the first index of refraction. A detection device of the system includes a low power light source used to direct light into the sample and generate an anti-resonant optical mode in the sample, and an analyzing system to detect the interaction of the light propagating in the sample.
摘要翻译：一种样本检测系统，包括反谐振波导，包括具有第一折射率的样品，顶层和围绕样品的基底，其中顶层具有第二折射率，并且所述基底具有第三指数折射。第二折射率和第三折射率均大于第一折射率。该系统的检测装置包括用于将光引入样品并在样品中产生反谐振光学模式的低功率光源，以及用于检测在样品中传播的光的相互作用的分析系统。

5. 发明授权

US07310153B2 Using position-sensitive detectors for wavelength determination 有权
标题翻译：使用位置敏感检测器进行波长测定
公开(公告)号：US07310153B2
公开(公告)日：2007-12-18
申请号：US10922870
申请日：2004-08-23
申请人： Peter Kiesel , Oliver Schmidt , Oliver Wolst
发明人： Peter Kiesel , Oliver Schmidt , Oliver Wolst
IPC分类号： G01B9/02
CPC分类号： G01J9/0246 , G01J3/26
摘要： A chip-size wavelength detector includes a film with laterally varying transmission properties and a position-sensitive detector. The film transmits a different wavelength as a function of lateral position across the film. The position of a spot of light transmitted through the film will shift, depending on the wavelength of the light. The shift is measured by the position-sensitive detector.
摘要翻译：芯片尺寸波长检测器包括具有横向变化的透射特性的膜和位置敏感检测器。薄膜透过不同的波长作为跨膜的横向位置的函数。透过薄膜的光斑的位置将根据光的波长而移动。位移由位置敏感检测器测量。

6. 发明申请

US20070146701A1 Fluorescence reader based on anti-resonant waveguide excitation 有权
公开(公告)号：US20070146701A1
公开(公告)日：2007-06-28
申请号：US11315797
申请日：2005-12-22
申请人： Peter Kiesel , Oliver Wolst , Michael Kneissl , Huangpin Hsieh , Oliver Schmidt
发明人： Peter Kiesel , Oliver Wolst , Michael Kneissl , Huangpin Hsieh , Oliver Schmidt
IPC分类号： G01J3/30 , G01N21/64
CPC分类号： G01N21/645 , G01N21/03 , G01N21/0303 , G01N21/05 , G01N21/31 , G01N21/33 , G01N21/35 , G01N21/3504 , G01N21/3577 , G01N21/3581 , G01N21/59 , G01N21/64 , G01N21/6456 , G01N2021/0346 , G01N2021/058 , G01N2021/513 , G01N2021/6467 , G01N2021/6469 , G01N2021/6493
摘要： A sample detection system including an anti-resonant waveguide, including a sample having a first index of refraction, a top layer and a substrate surrounding the sample, where the top layer has a second index of refraction, and the substrate has a third index of refraction. The second index of refraction, and the third index of refraction are both greater than the first index of refraction. A detection device of the system includes a low power light source used to direct light into the sample and generate an anti-resonant optical mode in the sample, and an analyzing system to detect the interaction of the light propagating in the sample.

7. 发明授权

US09164037B2 Method and system for evaluation of signals received from spatially modulated excitation and emission to accurately determine particle positions and distances 有权
标题翻译：用于评估从空间调制的激发和发射接收的信号的方法和系统，以准确地确定粒子位置和距离
公开(公告)号：US09164037B2
公开(公告)日：2015-10-20
申请号：US11698338
申请日：2007-01-26
申请人： Michael Bassler , Peter Kiesel , Oliver Schmidt
发明人： Michael Bassler , Peter Kiesel , Oliver Schmidt
IPC分类号： G01N33/48 , G01N21/64 , G06F19/00 , G06F19/12 , G01N31/00 , G06G7/58 , G01N15/10 , G01N15/14
CPC分类号： G01N21/6408 , G01N21/6458 , G01N2015/1075 , G01N2015/1486 , G06F19/12 , G06F2217/16 , G16H50/20
摘要： A method is provided for extracting the position of a particle, e.g., a moving or stationary particle that is excited or is emitting light. The method includes, among other steps, detecting and recording a signal based on, for example, the movement of the particle, a correlation step to eliminate noise and to create a transformed signal, a matching or fitting step to match the transformed signal to a fit function and an extracting or determining step to determine the position of the particle from the fit function. In one form, at least two particle positions are detected so that the distance between the subject particles can be determined.
摘要翻译：提供了用于提取颗粒的位置的方法，例如被激发或正在发光的移动或静止的颗粒。除了其他步骤之外，该方法包括基于例如粒子的移动来检测和记录信号，消除噪声并产生变换信号的相关步骤，匹配或拟合步骤，以将变换后的信号与拟合函数和提取或确定步骤以从拟合函数确定粒子的位置。在一种形式中，检测至少两个颗粒位置，使得可以确定主体颗粒之间的距离。

8. 发明授权

US08120782B2 Processes for producing tunable optical cavities 有权
标题翻译：用于生产可调谐光腔的工艺
公开(公告)号：US08120782B2
公开(公告)日：2012-02-21
申请号：US12603627
申请日：2009-10-22
申请人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Uma Srinivasan
发明人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Uma Srinivasan
IPC分类号： G01B9/02
CPC分类号： G01J3/26 , G01N21/45 , G01N2021/451 , G02B26/001
摘要： A tunable optical cavity can be tuned by relative movement between two reflection surfaces, such as by deforming elastomer spacers connected between mirrors or other light-reflective components that include the reflection surfaces. The optical cavity structure includes an analyte region in its light-transmissive region, and presence of analyte in the analyte region affects output light when the optical cavity is tuned to a set of positions. Electrodes that cause deformation of the spacers can also be used to capacitively sense the distance between them. Control circuitry that provides tuning signals can cause continuous movement across a range of positions, allowing continuous photosensing of analyte-affected output light by a detector.
摘要翻译：可调光学腔可以通过两个反射表面之间的相对运动进行调节，例如通过变形连接在反射镜之间的弹性体隔离物或包括反射表面的其它光反射部件。光腔结构包括其透光区域中的分析物区域，并且当光学腔被调谐到一组位置时，分析物区域中的分析物的存在影响输出光。导致间隔物变形的电极也可用于电容地感测它们之间的距离。提供调谐信号的控制电路可以在一定范围的位置上引起连续的运动，从而允许由检测器对被分析物影响的输出光进行持续的光敏。

9. 发明授权

US07936463B2 Containing analyte in optical cavity structures 有权
标题翻译：含有光学腔结构中的分析物
公开(公告)号：US07936463B2
公开(公告)日：2011-05-03
申请号：US11702325
申请日：2007-02-05
申请人： Peter Kiesel , Oliver Schmidt , Michael Bassler
发明人： Peter Kiesel , Oliver Schmidt , Michael Bassler
IPC分类号： G01B9/02
CPC分类号： G01N21/0303 , G01N21/05 , G01N21/253 , G01N2021/0346
摘要： A device can include both a photosensing component and an optical cavity structure, with the optical cavity structure including a part that can operate as an optical cavity in response to input light, providing laterally varying output light. For example, the optical cavity can be a graded linearly varying filter (LVF) or other inhomogeneous optical cavity, and the photosensing component can have a photosensitive surface that receives its output light without it passing through another optical component, thus avoiding loss of information. The optical cavity part can include a region that can contain analyte. Presence of the analyte affects the optical cavity part's output light, and the photosensing component can respond to the output light, providing sensing results indicating the analyte's optical characteristics.
摘要翻译：设备可以包括光敏元件和光学腔结构，其中光学腔结构包括响应于输入光可以作为光腔工作的部件，提供横向变化的输出光。例如，光学腔可以是渐变的线性变化的滤光器（LVF）或其他不均匀的光学腔，并且光敏元件可以具有接收其输出光而不通过另一个光学部件的感光表面，从而避免信息的丢失。光腔部分可以包括可以含有分析物的区域。分析物的存在影响光腔部分的输出光，并且光敏元件可以对输出光进行响应，提供指示分析物的光学特性的感测结果。

10. 发明授权

US07817281B2 Tuning optical cavities 有权
标题翻译：调谐光腔
公开(公告)号：US07817281B2
公开(公告)日：2010-10-19
申请号：US11702320
申请日：2007-02-05
申请人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Uma Srinivasan
发明人： Peter Kiesel , Oliver Schmidt , Michael Bassler , Uma Srinivasan
IPC分类号： G01B9/02
CPC分类号： H01S3/08081 , G01J3/26 , H01S3/105
摘要： An inhomogeneous optical cavity is tuned by changing its shape, such as by changing reflection surface positions to change tilt angle, thickness, or both. Deformable components such as elastomer spacers can be connected so that, when deformed, they change relative positions of structures with light-reflective components such as mirrors, changing cavity shape. Electrodes can cause deformation, such as electrostatically, electromagnetically, or piezoelectrically, and can also be used to measure thicknesses of the cavity. The cavity can be tuned, for example, across a continuous spectrum, to a specific wavelength band, to a shape that increases or decreases the number of modes it has, to a series of transmission ranges each suitable for a respective light source, with a modulation that allows lock-in with photosensing for greater sensitivity, and so forth. The optical cavity can be a linear variable filter fabricated on the photosensitive surface of a photosensing component such as a photosensor array or a position-sensitive detector.
摘要翻译：通过改变其形状来调整不均匀的光学腔，例如通过改变反射面位置来改变倾斜角，厚度或两者。变形部件如弹性体间隔件可以连接，使得当变形时，它们改变结构与诸如反射镜的光反射部件的相对位置，改变腔体形状。电极可能导致变形，例如静电，电磁或压电，也可用于测量腔的厚度。空腔可以例如通过连续光谱被调谐到特定波长带，以使其具有的模式数量增加或减少的形状调整到各自适用于相应光源的一系列传输范围，其中允许通过光敏锁定来实现更高灵敏度的调制，等等。光腔可以是制造在诸如光电传感器阵列或位置敏感检测器的感光部件的感光表面上的线性可变滤波器。

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