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1. 发明授权

US09642592B2 Needle enhancement in diagnostic ultrasound imaging 有权
公开(公告)号：US09642592B2
公开(公告)日：2017-05-09
申请号：US13733310
申请日：2013-01-03
申请人： Peng Wang , Terrence Chen , Ali Kamen , Jeffrey Stoll , Dorin Comaniciu , Sara Good
发明人： Peng Wang , Terrence Chen , Ali Kamen , Jeffrey Stoll , Dorin Comaniciu , Sara Good
IPC分类号： A61B8/00 , A61B8/08
CPC分类号： A61B8/0841 , A61B8/461 , A61B8/5246
摘要： A needle is enhanced in a medical diagnostic ultrasound image. The image intensities associated with a needle in an image are adaptively increased and/or enhanced by compounding from a plurality of ultrasound images. Filtering methods and probabilistic methods are used to locate possible needle locations. In one approach, possible needles are found in component frames that are acquired at the same time but at different beam orientations. The possible needles are associated with each other across the component frames and false detections are removed based on the associations. In one embodiment of needle detection in an ultrasound component frame, lines are found first. The lines are then searched to find possible needle segments. In another embodiment, data from different times may be used to find needle motion and differences from a reference, providing the features in additional to features from a single component frame for needle detection.

2. 发明申请

US20140187942A1 Needle Enhancement in Diagnostic Ultrasound Imaging 有权
标题翻译：针刺增强诊断超声成像
公开(公告)号：US20140187942A1
公开(公告)日：2014-07-03
申请号：US13733310
申请日：2013-01-03
申请人： Peng Wang , Terrence Chen , Ali Kamen , Jeffrey Stoll , Dorin Comaniciu , Sara Good
发明人： Peng Wang , Terrence Chen , Ali Kamen , Jeffrey Stoll , Dorin Comaniciu , Sara Good
IPC分类号： A61B8/08
CPC分类号： A61B8/0841 , A61B8/461 , A61B8/5246
摘要： A needle is enhanced in a medical diagnostic ultrasound image. The image intensities associated with a needle in an image are adaptively increased and/or enhanced by compounding from a plurality of ultrasound images. Filtering methods and probabilistic methods are used to locate possible needle locations. In one approach, possible needles are found in component frames that are acquired at the same time but at different beam orientations. The possible needles are associated with each other across the component frames and false detections are removed based on the associations. In one embodiment of needle detection in an ultrasound component frame, lines are found first. The lines are then searched to find possible needle segments. In another embodiment, data from different times may be used to find needle motion and differences from a reference, providing the features in additional to features from a single component frame for needle detection.
摘要翻译：在医疗诊断超声图像中增强针。通过从多个超声图像的复合来自适应地增加和/或增强与图像中的针相关联的图像强度。使用过滤方法和概率方法来定位可能的针位置。在一种方法中，可以在同时获取但是以不同波束取向获得的分量帧中找到可能的针。可能的针在组件框架之间彼此相关联，并且基于关联来去除错误检测。在超声组件框架中的针检测的一个实施例中，首先找到线。然后搜索线以找到可能的针段。在另一个实施例中，来自不同时间的数据可用于从参考找到针运动和差异，从单个组件框架中提供用于针检测的特征附加的特征。

3. 发明授权

US08737725B2 Method and system for learning based object detection in medical images 有权
标题翻译：医学图像学习基于物体检测的方法与系统
公开(公告)号：US08737725B2
公开(公告)日：2014-05-27
申请号：US13235747
申请日：2011-09-19
申请人： Peng Wang , Terrence Chen , Shaohua Kevin Zhou , Dorin Comaniciu , Martin Ostermeier
发明人： Peng Wang , Terrence Chen , Shaohua Kevin Zhou , Dorin Comaniciu , Martin Ostermeier
IPC分类号： G06K9/62
CPC分类号： G06K9/4614 , G06K9/6257 , G06K9/6282
摘要： Methods and Systems for training a learning based classifier and object detection in medical images is disclosed. In order to train a learning based classifier, positive training samples and negative training samples are generated based on annotated training images. Features for the positive training samples and the negative training samples are extracted. The features include an extended Haar feature set including tip features and corner features. A discriminative classifier is trained based on the extracted features.
摘要翻译：公开了用于训练医学图像中基于学习的分类器和对象检测的方法和系统。为了训练基于学习的分类器，基于注释的训练图像生成正训练样本和负训练样本。提取正训练样本和负训练样本的特征。功能包括扩展的Haar功能集，包括提示功能和角特征。基于提取的特征对歧视性分类器进行训练。

4. 发明授权

US08675914B2 Method and system for needle tracking in fluoroscopic image sequences 有权
标题翻译：透视图像序列中针跟踪的方法和系统
公开(公告)号：US08675914B2
公开(公告)日：2014-03-18
申请号：US12880319
申请日：2010-09-13
申请人： Peng Wang , Marcus Pfister , Terrence Chen , Martin Ostermeier , Dorin Comaniciu
发明人： Peng Wang , Marcus Pfister , Terrence Chen , Martin Ostermeier , Dorin Comaniciu
IPC分类号： G06K9/00
CPC分类号： A61B6/12
摘要： A method and system for tracking a needle in a fluoroscopic image sequence is disclosed. In order to track a needle in a fluoroscopic image sequence, the needle is initialized in a first frame of the fluoroscopic image sequence. Needle segments are detected in each subsequent frame of the fluoroscopic image sequence, and the needle is detected in each frame of the fluoroscopic image by tracking the needle from a previous frame of the fluoroscopic image sequence based on the detected needle segments in the current frame.
摘要翻译：公开了一种用于在荧光镜像图像序列中跟踪针的方法和系统。为了在透视图像序列中跟踪针，在荧光镜图像序列的第一帧中初始化针。在透视图像序列的每个随后的帧中检测针段，并且基于当前帧中检测到的针段，通过从荧光透视图像序列的先前帧跟踪针来在荧光镜图像的每个帧中检测针。

5. 发明授权

US08423121B2 Method and system for guidewire tracking in fluoroscopic image sequences 有权
标题翻译：荧光图像序列中导丝跟踪的方法和系统
公开(公告)号：US08423121B2
公开(公告)日：2013-04-16
申请号：US12538456
申请日：2009-08-10
申请人： Peng Wang , Ying Zhu , Wei Zhang , Terrence Chen , Peter Durlak , Ulrich Bill , Dorin Comaniciu
发明人： Peng Wang , Ying Zhu , Wei Zhang , Terrence Chen , Peter Durlak , Ulrich Bill , Dorin Comaniciu
IPC分类号： A61B5/05
CPC分类号： A61B6/12 , A61B2034/2065 , A61B2090/376 , G06T7/246 , G06T2207/10016 , G06T2207/10121 , G06T2207/30021
摘要： A method and system for tracking a guidewire in a fluoroscopic image sequence is disclosed. In order to track a guidewire in a fluoroscopic image sequence, guidewire segments are detected in each frame of the fluoroscopic image sequence. The guidewire in each frame of the fluoroscopic image sequence is then detected by rigidly tracking the guidewire from a previous frame of the fluoroscopic image sequence based on the detected guidewire segments in the current frame. The guidewire is then non-rigidly deformed in each frame based on the guidewire position in the previous frame.
摘要翻译：公开了一种用于跟踪透视图像序列中的导丝的方法和系统。为了在透视图像序列中跟踪导丝，在荧光镜图像序列的每个帧中检测导丝段。然后通过基于当前帧中检测到的导丝段从透视图像序列的前一帧刚性跟踪导丝来检测透视图像序列的每个帧中的导丝。然后基于先前框架中的导丝线位置，导丝在每个框架中不会刚性变形。

6. 发明申请

US20120059253A1 Method and System for Image Based Device Tracking for Co-registration of Angiography and Intravascular Ultrasound Images 有权
标题翻译：用于血管造影和血管内超声图像共同配准的基于图像的设备跟踪的方法和系统
公开(公告)号：US20120059253A1
公开(公告)日：2012-03-08
申请号：US13171560
申请日：2011-06-29
申请人： Peng Wang , Simone Prummer , Terrence Chen , Dorin Comaniciu , Olivier Ecabert , Martin Ostermeier
发明人： Peng Wang , Simone Prummer , Terrence Chen , Dorin Comaniciu , Olivier Ecabert , Martin Ostermeier
IPC分类号： A61B6/00 , A61B8/00
CPC分类号： A61B8/0891 , A61B6/00 , A61B6/12 , A61B6/481 , A61B6/487 , A61B6/504 , A61B6/5247 , A61B8/12 , A61B8/5238 , G06T7/251 , G06T2207/10121 , G06T2207/10132
摘要： A method and system for co-registration of angiography data and intra vascular ultrasound (IVUS) data is disclosed. A vessel branch is detected in an angiogram image. A sequence of IVUS images is received from an IVUS transducer while the IVUS transducer is being pulled back through the vessel branch. A fluoroscopic image sequence is received while the IVUS transducer is being pulled back through the vessel branch. The IVUS transducer and a guiding catheter tip are detected in each frame of the fluoroscopic image sequence. The IVUS transducer detected in each frame of the fluoroscopic image sequence is mapped to a respective location in the detected vessel branch of the angiogram image. Each of the IVUS images is registered to a respective location in the detected vessel branch of the angiogram image based on the mapped location of the IVUS transducer detected in a corresponding frame of the fluoroscopic image sequence.
摘要翻译：公开了用于血管造影数据和血管内超声（IVUS）数据共同配准的方法和系统。在血管造影图像中检测血管分支。当IVUS传感器被拉回血管分支时，从IVUS换能器接收一系列IVUS图像。当IVUS传感器被拉回通过血管分支时，接收透视图像序列。在荧光镜图像序列的每个帧中检测IVUS换能器和引导导管尖端。在荧光镜像图像序列的每个帧中检测到的IVUS换能器被映射到血管造影图像的检测到的血管分支中的相应位置。基于在荧光镜像图像序列的相应帧中检测到的IVUS换能器的映射位置，将每个IVUS图像登记在血管造影图像的检测的血管分支中的相应位置。

7. 发明授权

US09524550B2 System and method for coronary digital subtraction angiography 有权
标题翻译：冠状动脉数字减影血管造影的系统和方法
公开(公告)号：US09524550B2
公开(公告)日：2016-12-20
申请号：US12774146
申请日：2010-05-05
申请人： Ying Zhu , Simone Prummer , Peng Wang , Terrence Chen , Martin Ostermeier , Dorin Comaniciu
发明人： Ying Zhu , Simone Prummer , Peng Wang , Terrence Chen , Martin Ostermeier , Dorin Comaniciu
IPC分类号： G06T7/00
CPC分类号： G06T7/0016 , G06T2207/10121 , G06T2207/20224 , G06T2207/30101
摘要： A method and system for extracting coronary vessels fluoroscopic image sequences using coronary digital subtraction angiography (DSA) are disclosed. A set of mask images of a coronary region is received, and a sequence of contrast images for the coronary region is received. For each contrast image, a motion estimate is calculated between each of the mask images and a background region of the contrast image and a covariance is calculated for each motion estimate. Multiple background layer predictions are generated by generating a background layer prediction for each mask image based on the calculated motion estimate and covariance. The multiple background layer estimates are combined using statistical fusion to generate a final estimated background layer. The final estimated background layer is subtracted from the contrast image to extract a coronary vessel layer for the contrast image.
摘要翻译：公开了使用冠状动脉数字减影血管造影（DSA）提取冠脉血管荧光镜图像序列的方法和系统。接收冠状动脉区域的一组掩模图像，并且接收冠状动脉区域的对比度图像序列。对于每个对比度图像，在每个掩模图像和对比度图像的背景区域之间计算运动估计，并且针对每个运动估计计算协方差。通过基于计算的运动估计和协方差为每个掩模图像生成背景层预测来生成多个背景层预测。使用统计融合来组合多个背景层估计以产生最终估计的背景层。从对比度图像中减去最终估计的背景层，以提取对比度图像的冠状血管层。

8. 发明申请

US20110221754A1 Method and System for Graph Based Interactive Detection of Curve Structures in 2D Fluoroscopy 有权
标题翻译：二维荧光透视曲线结构图形交互检测方法与系统
公开(公告)号：US20110221754A1
公开(公告)日：2011-09-15
申请号：US13041818
申请日：2011-03-07
申请人： Peng Wang , Wei-shing Liao , Terrence Chen , Dorin Comaniciu
发明人： Peng Wang , Wei-shing Liao , Terrence Chen , Dorin Comaniciu
IPC分类号： G06T11/20
CPC分类号： G06K9/469 , G06K9/6892 , G06T7/12 , G06T7/162 , G06T7/181 , G06T11/203 , G06T11/206 , G06T2207/10121 , G06T2207/10124 , G06T2207/30021
摘要： A method and system for detecting a curve structure in a 2D fluoroscopic image is disclosed. A plurality of curve segments are detected in the image. A graph is generated based on the detected curve segments. A curve structure is detected in the image by determining a path between a source node and a destination node in the graph. A hyper-graph can be constructed from the graph in order to impose geometric constraints on segments of the detected the curve structure, and the curve structure can be detected by finding a shortest path in the hyper-graph.
摘要翻译：公开了一种用于检测2D透视图像中的曲线结构的方法和系统。在图像中检测多个曲线段。基于检测到的曲线段生成图形。通过确定图中的源节点和目的地节点之间的路径，在图像中检测曲线结构。可以从图中构建超图，以便在检测到的曲线结构的段上施加几何约束，并且可以通过在超图中找到最短路径来检测曲线结构。

9. 发明申请

US20110064189A1 Method and System for Needle Tracking in Fluoroscopic Image Sequences 有权
标题翻译：荧光图像序列中针跟踪的方法和系统
公开(公告)号：US20110064189A1
公开(公告)日：2011-03-17
申请号：US12880319
申请日：2010-09-13
申请人： Peng Wang , Marcus Pfister , Terrence Chen , Martin Ostermeier , Dorin Comaniciu
发明人： Peng Wang , Marcus Pfister , Terrence Chen , Martin Ostermeier , Dorin Comaniciu
IPC分类号： A61B6/02
CPC分类号： A61B6/12
摘要： A method and system for tracking a needle in a fluoroscopic image sequence is disclosed. In order to track a needle in a fluoroscopic image sequence, the needle is initialized in a first frame of the fluoroscopic image sequence. Needle segments are detected in each subsequent frame of the fluoroscopic image sequence, and the needle is detected in each frame of the fluoroscopic image by tracking the needle from a previous frame of the fluoroscopic image sequence based on the detected needle segments in the current frame.
摘要翻译：公开了一种用于在荧光镜像图像序列中跟踪针的方法和系统。为了在透视图像序列中跟踪针，在荧光镜图像序列的第一帧中初始化针。在透视图像序列的每个随后的帧中检测针段，并且基于当前帧中检测到的针段，通过从荧光透视图像序列的先前帧跟踪针来在荧光镜图像的每个帧中检测针。

10. 发明授权

US08892186B2 Method and system for detection and tracking of coronary sinus catheter electrodes in fluoroscopic images 有权
标题翻译：荧光镜检查和跟踪冠状静脉窦导管电极的方法和系统
公开(公告)号：US08892186B2
公开(公告)日：2014-11-18
申请号：US13229855
申请日：2011-09-12
申请人： Wen Wu , Terrence Chen , Peng Wang , Norbert Strobel , Shaohua Kevin Zhou , Dorin Comaniciu
发明人： Wen Wu , Terrence Chen , Peng Wang , Norbert Strobel , Shaohua Kevin Zhou , Dorin Comaniciu
IPC分类号： A61B5/05 , G06T7/00 , G06T7/20 , A61B19/00
CPC分类号： G06T7/0014 , A61B2034/2065 , A61B2090/376 , G06K2209/057 , G06T7/20 , G06T2207/10121 , G06T2207/30021 , G06T2207/30048
摘要： A method and system for detecting and tracking coronary sinus (CS) catheter electrodes in a fluoroscopic image sequence is disclosed. An electrode model is initialized in a first frame of the fluoroscopic image sequence based on input locations of CS sinus catheter electrodes in the first frame. The electrode model is tracked in subsequent frames of the fluoroscopic image sequence by detecting electrode position candidates in the subsequent frames of the fluoroscopic image sequence using at least one trained electrode detector, generating electrode model candidates in the subsequent frames based on the detected electrode position candidates, calculating a probability score for each of the electrode model candidates, and selecting an electrode model candidate based on the probability score.
摘要翻译：公开了一种用于在荧光镜图像序列中检测和跟踪冠状窦（CS）导管电极的方法和系统。基于第一帧中的CS窦导管电极的输入位置，在荧光镜图像序列的第一帧中初始化电极模型。通过使用至少一个经过训练的电极检测器检测荧光镜像图像序列的后续帧中的电极位置候选物，在荧光图像序列的后续帧中跟踪电极模型，基于检测到的电极位置候选产生后续帧中的电极模型候选计算每个电极模型候选的概率分数，并且基于概率分数来选择电极模型候选。

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