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    • 4. 发明授权
    • Automatically arranging of icons on a user interface
    • 在用户界面上自动排列图标
    • US08930839B2
    • 2015-01-06
    • US13301792
    • 2011-11-22
    • Li HePeng Liu
    • Li HePeng Liu
    • G06F3/048G06F3/0481
    • G06F3/04817
    • Automatically arranging icons on a user interface is provided. A plurality of icons associated with items are received and displayed on the user interface. An importance score for each icon of the plurality of icons and a similarity score between two or more of the plurality of icons are determined. Further, a user interface coordinate is assigned to at least a portion of the plurality of icons based on the importance and similarity scores. The user interface is then displayed with the at least a portion of the plurality of icons according to the user interface coordinate.
    • 提供在用户界面上自动排列图标。 与项目相关联的多个图标被接收并显示在用户界面上。 确定多个图标的每个图标的重要性得分以及多个图标中的两个或更多个图标之间的相似性得分。 此外,基于重要性和相似性得分,向多个图标的至少一部分分配用户界面坐标。 然后根据用户界面坐标与多个图标的至少一部分显示用户界面。
    • 5. 发明授权
    • Heater
    • 加热器
    • US08841588B2
    • 2014-09-23
    • US12589828
    • 2009-10-29
    • Peng LiuLiang LiuKai-Li JiangShou-Shan Fan
    • Peng LiuLiang LiuKai-Li JiangShou-Shan Fan
    • H05B3/06H05B3/14
    • H05B3/145H05B2203/032H05B2214/04
    • A heater includes a substrate, a plurality of first electrode down-leads, a plurality of second electrode down-leads and a plurality of heating units. The plurality of first electrode down-leads are located on the substrate in parallel to each other and the plurality of second electrode down-leads are located on the substrate in parallel to each other. The first electrode down-leads cross the second electrode down-leads and define a plurality of grids. One heating unit is located in each grid. Each heating unit includes a first electrode, a second electrode and a heating element. The heating element includes a carbon nanotube structure.
    • 加热器包括基板,多个第一电极下引线,多个第二电极下引线和多个加热单元。 多个第一电极下引线彼此平行地位于基板上,并且多个第二电极下引线彼此平行地位于基板上。 第一电极下引线穿过第二电极下引线并限定多个栅极。 一个加热单元位于每个网格中。 每个加热单元包括第一电极,第二电极和加热元件。 加热元件包括碳纳米管结构。
    • 8. 发明授权
    • Compositions and methods for bone formation and remodeling
    • 用于骨形成和重塑的组合物和方法
    • US08637506B2
    • 2014-01-28
    • US10849067
    • 2004-05-19
    • Dianqing WuYazhou ZhangPeng LiuXiaofeng LiJie ZhangJufang ShanDean Engelhardt
    • Dianqing WuYazhou ZhangPeng LiuXiaofeng LiJie ZhangJufang ShanDean Engelhardt
    • A61K31/535C07C50/18
    • G01N33/6893A61K38/00G01N33/6887G01N2500/00G01N2800/10G01N2800/108
    • The mechanism by which the high bone mass (HBM) mutation (G171V) of the Wnt coreceptor LRP5 regulates the canonical Wnt signaling was investigated. The mutation was previously shown to reduce Dkk protein-1-mediated antagonism, suggesting that the first YWTD repeat domain where G171 is located may be responsible for Dkk protein-mediated antagonism. However, we found that the third YWTD repeat, but not the first repeat domain, is required for DKK1-mediated antagonism. Instead, we found that the G171V mutation disrupted the interaction of LRP5 with Mesd, a chaperon protein for LRP5/6 that is required for the coreceptors' transport to cell surfaces, resulting in less LRP5 molecules on the cell surface. Although the reduction in the level of cell surface LRP5 molecules led to a reduction in Wnt signaling in a paracrine paradigm, the mutation did not appear to affect the activity of coexpressed Wnt in an autocrine paradigm. Together with the observation that osteoblast cells produce autocrine canonical Wnt, Wnt7b, and that osteocytes produce paracrine Dkk1, we believe that the G171V mutation may cause an increase in Wnt activity in osteoblasts by reducing the number of targets for paracrine Dkk1 to antagonize without affecting the activity of autocrine Wnt.
    • 研究了Wnt共同受体LRP5的高骨量(HBM)突变(G171V)调节规范Wnt信号传导的机制。 以前显示突变可以降低Dkk蛋白-1介导的拮抗作用,这表明G171位于第一个YWTD重复结构域可能是Dkk蛋白介导的拮抗作用的原因。 然而,我们发现第三个YWTD重复,但不是第一个重复结构域,是DKK1介导的拮抗作用所必需的。 相反,我们发现G171V突变破坏了LRP5与Mesd的相互作用,Mesd是共受体转运到细胞表面所需的LRP5 / 6的伴侣蛋白,导致细胞表面上较少的LRP5分子。 尽管细胞表面LRP5分子水平的降低导致旁分泌范例中Wnt信号传导的降低,但突变似乎不影响共表达Wnt在自分泌范式中的活性。 连同观察到成骨细胞产生自分泌的正常Wnt,Wnt7b,并且该骨细胞产生旁分泌的Dkk1,我们认为G171V突变可能通过减少旁分泌Dkk1靶向拮抗的目标数量引起成骨细胞中Wnt活性的增加,而不会影响 自分泌Wnt的活性。
    • 9. 发明授权
    • Selecting advertisements for placement on related web pages
    • 选择在相关网页上放置广告
    • US08620745B2
    • 2013-12-31
    • US13381037
    • 2010-12-27
    • Siyu YouPeng Liu
    • Siyu YouPeng Liu
    • G06Q30/00
    • G06F17/3089G06Q30/0241G06Q30/0243
    • Systems and methods are described that select advertisements for placement on a series of consecutively-accessed web pages, such as consecutively-accessed web search results pages generated in response to a particular search. The systems and methods perform a separate advertisement ranking process to select advertisements for placement on each web page in the series of consecutively-accessed web pages at the time the web page is accessed. For web pages that follow the first web page in the series, the systems and methods utilize an advertisement ranking technique that calculates a probability that a user will select an advertisement based on certain user selection feedback features. The user selection feedback features for an advertisement are determined by comparing attributes of the advertisement to attributes of user-selectable items that were presented on one or more of the previously-accessed web pages in the series that are known to have been selected or not selected by the user.
    • 描述了系统和方法,其选择用于放置在一系列连续访问的网页上的广告,诸如响应于特定搜索生成的连续访问的网页搜索结果页面。 系统和方法执行单独的广告排序过程,以在访问网页时选择在连续访问的一系列网页中的每个网页上的布置的广告。 对于遵循该系列中的第一网页的网页,系统和方法利用广告排序技术,其计算用户将基于特定用户选择反馈特征来选择广告的概率。 用于广告的用户选择反馈特征通过将广告的属性与在系列中已被选择或未被选择的一个或多个先前访问的网页上呈现的用户可选项目的属性进行比较来确定 由用户
    • 10. 发明授权
    • Thermochromatic device and thermochromatic display apparatus
    • 热色设备和热色显示设备
    • US08614849B2
    • 2013-12-24
    • US12884641
    • 2010-09-17
    • Peng LiuShou-Shan Fan
    • Peng LiuShou-Shan Fan
    • G02F1/01
    • C09K9/02C09K2211/1425C09K2211/1458
    • A thermochromatic device includes an insulating substrate, a back color layer, a color element, a heating element, a first electrode, and a second electrode. The back color layer is located on the insulating substrate. The color element is located on the back color layer and includes a transparence-changeable material. The transparence-changeable material performs a transformation between a transparent state and a nontransparent state at a phase change temperature. The heating element is located adjacent to the color element and includes a carbon nanotube structure. The first electrode and the second electrode are electrically connected to the heating element. A thermochromatic display apparatus using the thermochromatic device is also related.
    • 一种热色设备包括绝缘基板,背色层,彩色元件,加热元件,第一电极和第二电极。 背色层位于绝缘基板上。 彩色元件位于背色层上,并包括透明度可变材料。 透明变色材料在相变温度下进行透明状态和非透明状态之间的变换。 加热元件位于颜色元件附近并且包括碳纳米管结构。 第一电极和第二电极电连接到加热元件。 使用热色设备的热色显示设备也是相关的。