专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20120171222A1 METHODS AND COMPOSITIONS INVOLVING NUCLEOTIDE REPEAT DISORDERS 有权
标题翻译：涉及核酸重复症状的方法和组合物
公开(公告)号：US20120171222A1
公开(公告)日：2012-07-05
申请号：US13419475
申请日：2012-03-14
申请人： Partha Sarkar , Tetsuo Ashizawa , Weidong Xu
发明人： Partha Sarkar , Tetsuo Ashizawa , Weidong Xu
IPC分类号： A61K31/7088 , A61K38/02 , A61K31/713 , A61K39/395 , C12N5/071 , A61P35/00 , A61P31/00 , A61P25/28 , C07H21/00 , C07K14/00 , C12N5/10 , C12N1/21 , A01K67/027 , C12P19/34 , A61P21/00 , A61K31/55 , A61K31/5513 , A61K31/47 , A61K31/40 , G01N27/62 , G01N33/82
CPC分类号： C12Q1/6883 , C12Q1/6897 , C12Q2600/158 , G01N33/6887 , G01N2500/02
摘要： The present invention concerns the methods and compositions involving nucleic acids with long repeat sequences. In some embodiments of the invention, there are methods for generating such a nucleic acid, and in other methods, there are methods for using such a nucleic acid to screen for candidate therapeutic compounds. Furthermore the present invention relates to methods of screening for Notch inhibitors and other substances that may be used to treat muscle loss and wasting.
摘要翻译：本发明涉及涉及具有长重复序列的核酸的方法和组合物。在本发明的一些实施方案中，存在产生这种核酸的方法，并且在其它方法中，存在使用这种核酸筛选候选治疗化合物的方法。此外，本发明涉及筛选Notch抑制剂和可用于治疗肌肉损失和浪费的其它物质的方法。

2. 发明授权

US08771965B2 Methods and compositions involving nucleotide repeat disorders 有权
标题翻译：涉及核苷酸重复障碍的方法和组合
公开(公告)号：US08771965B2
公开(公告)日：2014-07-08
申请号：US13419475
申请日：2012-03-14
申请人： Partha Sarkar , Tetsuo Ashizawa , Weidong Xu
发明人： Partha Sarkar , Tetsuo Ashizawa , Weidong Xu
IPC分类号： G01N33/53 , C12Q1/68 , C12Q1/00 , A61K38/00 , A61K48/00
CPC分类号： C12Q1/6883 , C12Q1/6897 , C12Q2600/158 , G01N33/6887 , G01N2500/02
摘要： The present invention concerns the methods and compositions involving nucleic acids with long repeat sequences. In some embodiments of the invention, there are methods for generating such a nucleic acid, and in other methods, there are methods for using such a nucleic acid to screen for candidate therapeutic compounds. Furthermore the present invention relates to methods of screening for Notch inhibitors and other substances that may be used to treat muscle loss and wasting.
摘要翻译：本发明涉及涉及具有长重复序列的核酸的方法和组合物。在本发明的一些实施方案中，存在产生这种核酸的方法，并且在其它方法中，存在使用这种核酸筛选候选治疗化合物的方法。此外，本发明涉及筛选Notch抑制剂和可用于治疗肌肉损失和浪费的其它物质的方法。

3. 发明申请

US20110033480A1 METHODS AND COMPOSITIONS INVOLVING NUCLEOTIDE REPEAT DISORDERS 有权
标题翻译：涉及核酸重复症状的方法和组合物
公开(公告)号：US20110033480A1
公开(公告)日：2011-02-10
申请号：US12296846
申请日：2007-04-11
申请人： Partha Sarkar , Tetsuo Ashizawa , Weidong XU
发明人： Partha Sarkar , Tetsuo Ashizawa , Weidong XU
IPC分类号： A61K39/395 , A61K31/713 , A61K38/02 , A61K31/7088 , A61P21/00 , G01N33/566
CPC分类号： C12Q1/6883 , C12Q1/6897 , C12Q2600/158 , G01N33/6887 , G01N2500/02
摘要： The present invention concerns the methods and compositions involving nucleic acids with long repeat sequences. In some embodiments of the invention, there are methods for generating such a nucleic acid, and in other methods, there are methods for using such a nucleic acid to screen for candidate therapeutic compounds. Furthermore the present invention relates to methods of screening for Notch inhibitors and other substances that may be used to treat muscle loss and wasting.
摘要翻译：本发明涉及涉及具有长重复序列的核酸的方法和组合物。在本发明的一些实施方案中，存在产生这种核酸的方法，并且在其它方法中，存在使用这种核酸筛选候选治疗化合物的方法。此外，本发明涉及筛选Notch抑制剂和可用于治疗肌肉损失和浪费的其它物质的方法。

4. 发明授权

US08158364B2 Methods and compositions involving nucleotide repeat disorders 有权
标题翻译：涉及核苷酸重复障碍的方法和组合
公开(公告)号：US08158364B2
公开(公告)日：2012-04-17
申请号：US12296846
申请日：2007-04-11
申请人： Partha Sarkar , Tetsuo Ashizwa , Weidong Xu
发明人： Partha Sarkar , Tetsuo Ashizwa , Weidong Xu
IPC分类号： G01N33/53 , C12Q1/68 , C12Q1/00
CPC分类号： C12Q1/6883 , C12Q1/6897 , C12Q2600/158 , G01N33/6887 , G01N2500/02
摘要： The present invention concerns the methods and compositions involving nucleic acids with long repeat sequences. In some embodiments of the invention, there are methods for generating such a nucleic acid, and in other methods, there are methods for using such a nucleic acid to screen for candidate therapeutic compounds. Furthermore the present invention relates to methods of screening for Notch inhibitors and other substances that may be used to treat muscle loss and wasting.
摘要翻译：本发明涉及涉及具有长重复序列的核酸的方法和组合物。在本发明的一些实施方案中，存在产生这种核酸的方法，并且在其它方法中，存在使用这种核酸筛选候选治疗化合物的方法。此外，本发明涉及筛选Notch抑制剂和可用于治疗肌肉损失和浪费的其它物质的方法。

5. 发明授权

US08349510B2 Solid state electrochemical cell having reticulated electrode matrix and method of manufacturing same 有权
标题翻译：具有网状电极基体的固态电化学电池及其制造方法
公开(公告)号：US08349510B2
公开(公告)日：2013-01-08
申请号：US12056169
申请日：2008-03-26
申请人： Partha Sarkar , Mark Lewis Richardson , Luis Yamarte , Lorne Johanson
发明人： Partha Sarkar , Mark Lewis Richardson , Luis Yamarte , Lorne Johanson
IPC分类号： H01M8/10
CPC分类号： H01M4/8885 , H01M4/8825 , H01M8/1213 , H01M8/124 , H01M8/243 , H01M2008/1293 , H01M2300/0074 , H01M2300/0094 , Y02P70/56
摘要： A solid state electrochemical cell comprises a dense electrolyte layer; at least one reticulated electrode matrix (REM) of ion-conducting material partially sintered on the gas impermeable electrolyte layer, and electrode material located substantially within the REM. The REM has a majority of pores with an average pore size of less than micron. The REM can also have a porosity of 5 to 80%, thickness at or below 3.00 microns, and a mean grain size of 0.01 to 3.00 microns.
摘要翻译：固态电化学电池包括致密的电解质层; 在气体不可渗透的电解质层上部分烧结的离子传导材料的至少一个网状电极基体（REM）和基本上位于REM内的电极材料。 REM具有平均孔径小于微米的大部分孔。 REM还可以具有5至80％的孔隙率，或等于或小于3.00微米的厚度，并且平均粒度为0.01至3.00微米。

6. 发明申请

US20080286625A1 SOLID STATE ELECTROCHEMICAL CELL HAVING RETICULATED ELECTRODE MATRIX AND METHOD OF MANUFACTURING SAME 有权
标题翻译：具有电极电极矩阵的固体电化学电池及其制造方法
公开(公告)号：US20080286625A1
公开(公告)日：2008-11-20
申请号：US12056169
申请日：2008-03-26
申请人： Partha Sarkar , Mark Lewis Richardson , Luis Yamarte , Lorne Johanson
发明人： Partha Sarkar , Mark Lewis Richardson , Luis Yamarte , Lorne Johanson
IPC分类号： H01M8/10 , B05D5/12 , B05D1/02 , B05D1/04 , C23C14/34
CPC分类号： H01M4/8885 , H01M4/8825 , H01M8/1213 , H01M8/124 , H01M8/243 , H01M2008/1293 , H01M2300/0074 , H01M2300/0094 , Y02P70/56
摘要： A solid state electrochemical cell comprises a dense electrolyte layer; at least one reticulated electrode matrix (REM) of ion-conducting material partially sintered on the gas impermeable electrolyte layer, and electrode material located substantially within the REM. The REM has a majority of pores with an average pore size of less than micron. The REM can also have a porosity of 5 to 80%, thickness at or below 3.00 microns, and a mean grain size of 0.01 to 3.00 microns.
摘要翻译：固态电化学电池包括致密的电解质层; 在气体不可渗透的电解质层上部分烧结的离子传导材料的至少一个网状电极基体（REM）和基本上位于REM内的电极材料。 REM具有平均孔径小于微米的大部分孔。 REM还可以具有5至80％的孔隙率，或等于或小于3.00微米的厚度，并且平均粒度为0.01至3.00微米。

7. 发明授权

US07258936B2 Controlling solid oxide fuel cell operation 有权
标题翻译：控制固体氧化物燃料电池运行
公开(公告)号：US07258936B2
公开(公告)日：2007-08-21
申请号：US10971592
申请日：2004-10-21
申请人： Rong Zheng , Hongsang Rho , Luis Yamarte , Gary J. Kovacik , Partha Sarkar
发明人： Rong Zheng , Hongsang Rho , Luis Yamarte , Gary J. Kovacik , Partha Sarkar
IPC分类号： H01M8/00 , H01M8/10
CPC分类号： H02J7/0032 , H01M8/0267 , H01M8/04007 , H01M8/04022 , H01M8/04089 , H01M8/04223 , H01M8/04246 , H01M8/04268 , H01M8/04302 , H01M8/04313 , H01M8/04365 , H01M8/04388 , H01M8/04395 , H01M8/04552 , H01M8/04559 , H01M8/04582 , H01M8/04589 , H01M8/04604 , H01M8/04731 , H01M8/04753 , H01M8/04776 , H01M8/0494 , H01M8/04955 , H01M8/2425 , H01M8/243 , H01M8/247 , H01M8/249 , H01M2008/1293 , H01M2250/30 , Y02B90/18
摘要： This invention relates to controlling a load-following solid oxide fuel cell system such that the fuel cells in the system are operating within an acceptable electrochemical reaction efficiency. The system has a controller that is programmed to detect a load change on a fuel cell stack, and when the load decreases, reduces the fuel flow rate to the stack or deactivates one or more fuel cells in the stack such that the stack operates within an acceptable electrochemical reaction efficiency range corresponding to the decreased load; and when the load increases, the controller increases the fuel flow rate to the stack or activates fuel cells in the stack such that the stack operates within the acceptable electrochemical reaction efficiency range.
摘要翻译：本发明涉及控制负载紧随固体氧化物燃料电池系统，使得系统中的燃料电池在可接受的电化学反应效率内工作。该系统具有被编程以检测燃料电池堆上的负载变化的控制器，并且当负载减小时，将燃料流量降低到堆栈或者使堆叠中的一个或多个燃料电池停用，使得堆栈在可接受的电化学反应效率范围对应于负载减少; 并且当负载增加时，控制器增加到堆叠的燃料流量或激活堆叠中的燃料电池，使得堆栈在可接受的电化学反应效率范围内操作。

8. 发明授权

US06607645B1 Production of hollow ceramic membranes by electrophoretic deposition 有权
标题翻译：通过电泳沉积生产中空陶瓷膜
公开(公告)号：US06607645B1
公开(公告)日：2003-08-19
申请号：US09583274
申请日：2000-05-31
申请人： Partha Sarkar
发明人： Partha Sarkar
IPC分类号： C08F258
CPC分类号： C25D13/14 , C04B38/00 , C04B38/065 , C04B41/009 , C04B41/5031 , C04B2111/00413 , C04B2111/00801 , C04B2111/00853 , C25D13/02 , H01M8/1231 , Y02P70/56 , C04B35/00 , C04B38/0003 , C04B38/007 , C04B38/06 , C04B38/069 , C04B41/4564 , C04B14/303 , C04B30/02
摘要： The present invention provides methods for producing hollow ceramic membranes by electrophoretic deposition. The hollow ceramic membranes may have a small cross-sectional area of about 1.0×10−5 mm2 to about 25 mm2. The cross-sectional configuration of the hollow ceramic membranes may be any geometry such as circular, square, rectangular, triangular or polygonal. The hollow ceramic membranes produced by the methods of the present invention may have multiple layers but always the innermost layer, or the first deposited layer is porous and made by electrophoretic deposition. Subsequent layers may be porous or non porous and deposited before or after sintering the first layer. If it is deposited after sintering, it may require additional sintering steps. Additional layers may be deposited by further electrophoretic deposition, sol-gel coating, dip coating, vacuum casting, brushing, spraying or other known techniques.
摘要翻译：本发明提供了通过电泳沉积制造中空陶瓷膜的方法。中空陶瓷膜可以具有约1.0×10-5mm2至约25mm2的小横截面积。中空陶瓷膜的横截面构造可以是任何几何形状，例如圆形，正方形，矩形，三角形或多边形。通过本发明的方法生产的中空陶瓷膜可以具有多层但总是最内层，或者第一沉积层是多孔的并且通过电泳沉积制成。随后的层可以是多孔的或非多孔的并且在烧结第一层之前或之后沉积。如果烧结后沉积，则可能需要额外的烧结步骤。可以通过进一步的电泳沉积，溶胶 - 凝胶涂覆，浸涂，真空浇铸，刷涂，喷雾或其它已知技术来沉积附加的层。

9. 发明授权

US07182848B2 Production of hollow ceramic membranes by electrophoretic deposition 有权
标题翻译：通过电泳沉积生产中空陶瓷膜
公开(公告)号：US07182848B2
公开(公告)日：2007-02-27
申请号：US10249735
申请日：2003-05-05
申请人： Partha Sarkar
发明人： Partha Sarkar
IPC分类号： B01D57/02
CPC分类号： C25D13/14 , C04B38/00 , C04B38/065 , C04B41/009 , C04B41/5031 , C04B2111/00413 , C04B2111/00801 , C04B2111/00853 , C25D13/02 , H01M8/1231 , Y02P70/56 , C04B35/00 , C04B38/0003 , C04B38/007 , C04B38/06 , C04B38/069 , C04B41/4564 , C04B14/303 , C04B30/02
摘要： The present invention provides methods for producing hollow ceramic membranes by electrophoretic deposition. The hollow ceramic membranes may have a small cross-sectional area of about 1.0×10−5 mm2 to about 25 mm2. The cross-sectional configuration of the hollow ceramic membranes may be any geometry such as circular, square, rectangular, triangular or polygonal. The hollow ceramic membranes produced by the methods of the present invention may have multiple layers but always the innermost layer, or the first deposited layer is porous and made by electrophoretic deposition. Subsequent layers may be porous or non porous and deposited before or after sintering the first layer. If it is deposited after sintering, it may require additional sintering steps. Additional layers may be deposited by further electrophoretic deposition, sol-gel coating, dip coating, vacuum casting, brushing, spraying or other known techniques.
摘要翻译：本发明提供了通过电泳沉积制造中空陶瓷膜的方法。中空陶瓷膜可以具有约1.0×10 -5 mm 2至约25mm 2的小的横截面积。中空陶瓷膜的横截面构造可以是任何几何形状，例如圆形，正方形，矩形，三角形或多边形。通过本发明的方法生产的中空陶瓷膜可以具有多层但总是最内层，或者第一沉积层是多孔的并且通过电泳沉积制成。随后的层可以是多孔的或非多孔的并且在烧结第一层之前或之后沉积。如果烧结后沉积，则可能需要额外的烧结步骤。可以通过进一步的电泳沉积，溶胶 - 凝胶涂覆，浸涂，真空浇铸，刷涂，喷雾或其它已知技术来沉积附加的层。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式