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1. 发明申请

WO2008073877B1 NOVEL BACILLUS THURINGIENSIS CRYSTAL POLYPEPTIDES, POLYNUCLEOTIDES, AND COMPOSITIONS THEREOF 审中-公开
公开(公告)号：WO2008073877B1
公开(公告)日：2008-12-18
申请号：PCT/US2007086947
申请日：2007-12-10
申请人： PIONEER HI BRED INT , CERF DAVID , CONG RUTH , FREEMAN MICHAEL , MCBRIDE KEVIN , YAMAMOTO TAKASHI
发明人： CERF DAVID , CONG RUTH , FREEMAN MICHAEL , MCBRIDE KEVIN , YAMAMOTO TAKASHI
IPC分类号： C12N15/82 , A01H5/00 , C07K14/325
CPC分类号： C12N15/8286 , C07K14/325 , Y02A40/162
摘要： The present invention provides insecticidal polypeptides related to shuffled Bacillus thuringiensis Cry1 polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nucleic acids of the invention to enhance resistance of plants to insect predation are encompassed.

2. 发明申请

WO2008073877A3 NOVEL BACILLUS THURINGIENSIS CRYSTAL POLYPEPTIDES, POLYNUCLEOTIDES, AND COMPOSITIONS THEREOF 审中-公开
公开(公告)号：WO2008073877A3
公开(公告)日：2008-10-23
申请号：PCT/US2007086947
申请日：2007-12-10
申请人： PIONEER HI BRED INT , CERF DAVID , CONG RUTH , FREEMAN MICHAEL , MCBRIDE KEVIN , YAMAMOTO TAKASHI
发明人： CERF DAVID , CONG RUTH , FREEMAN MICHAEL , MCBRIDE KEVIN , YAMAMOTO TAKASHI
IPC分类号： C12N15/82 , A01H5/00 , C07K14/325
CPC分类号： C12N15/8286 , C07K14/325 , Y02A40/162
摘要： The present invention provides insecticidal polypeptides related to shuffled Bacillus thuringiensis Cry1 polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nucleic acids of the invention to enhance resistance of plants to insect predation are encompassed.

3. 发明申请

WO2008073877A9 NOVEL BACILLUS THURINGIENSIS CRYSTAL POLYPEPTIDES, POLYNUCLEOTIDES, AND COMPOSITIONS THEREOF 审中-公开
标题翻译：新型苏云金芽孢杆菌晶体多肽，多核苷酸及其组合物
公开(公告)号：WO2008073877A9
公开(公告)日：2008-07-31
申请号：PCT/US2007086947
申请日：2007-12-10
申请人： PIONEER HI BRED INT , CERF DAVID , CONG RUTH , FREEMAN MICHAEL , MCBRIDE KEVIN , YAMAMOTO TAKASHI
发明人： CERF DAVID , CONG RUTH , FREEMAN MICHAEL , MCBRIDE KEVIN , YAMAMOTO TAKASHI
IPC分类号： C12N15/82 , A01H5/00 , C07K14/325
CPC分类号： C12N15/8286 , C07K14/325 , Y02A40/162
摘要： The present invention provides insecticidal polypeptides related to shuffled Bacillus thuringiensis Cry1 polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nucleic acids of the invention to enhance resistance of plants to insect predation are encompassed.
摘要翻译：本发明提供了与改组的苏云金芽孢杆菌Cry1多肽有关的杀虫多肽。还提供了编码本发明多肽的核酸。涵盖使用本发明的多肽和核酸增强植物对昆虫捕食的抗性的方法。

4. 发明申请

WO2014062544A2 METHODS AND COMPOSITIONS TO ENHANCE ACTIVITY OF CRY ENDOTOXINS 审中-公开
标题翻译：提高CRY内毒素活性的方法和组合物
公开(公告)号：WO2014062544A2
公开(公告)日：2014-04-24
申请号：PCT/US2013064784
申请日：2013-10-14
申请人： PIONEER HI BRED INT , CONG RUTH , YAMAMOTO TAKASHI , YI ZHENG
发明人： CONG RUTH , YAMAMOTO TAKASHI , YI ZHENG
IPC分类号： C12N15/82
CPC分类号： C12N15/8286 , C07K14/245 , C07K14/325 , C07K2319/20 , C07K2319/35 , C07K2319/55 , Y02A40/162
摘要： Methods and compositions for enhancing the resistance of plants to plant pests are provided. Chimeric pesticidal polypeptides and nucleic acid molecules encoding the chimeric pesticidal polypeptides are provided. The chimeric pesticidal polypeptides comprising a solubility-enhancing polypeptide operably linked to a polypeptide comprising pesticidal activity. The nucleic acid molecules can be used in expression cassettes for making transformed plants with enhanced resistance to plant pests. Further provided are transformed plants, plant tissues, plant cells, other host cells, and seeds as well as pesticidal compositions.
摘要翻译：提供了用于增强植物对植物害虫的抗性的方法和组合物。提供了嵌合杀虫多肽和编码嵌合杀虫多肽的核酸分子。所述嵌合杀虫多肽包含可操作地连接至包含杀虫活性的多肽的溶解度增强性多肽。核酸分子可用于表达盒中以制备对植物有害生物具有增强的抗性的转化植物。进一步提供了转化植物，植物组织，植物细胞，其他宿主细胞和种子以及农药组合物。

5. 发明申请

WO2014150914A3 PHI-4 POLYPEPTIDES AND METHODS FOR THEIR USE 审中-公开
标题翻译： PHI-4多肽及其使用方法
公开(公告)号：WO2014150914A3
公开(公告)日：2014-11-13
申请号：PCT/US2014024524
申请日：2014-03-12
申请人： PIONEER HI BRED INT , CONG RUTH , HOU JINGTONG , HOU ZHENGLIN , PATTEN PHILLIP A , YAMAMOTO TAKASHI
发明人： CONG RUTH , HOU JINGTONG , HOU ZHENGLIN , PATTEN PHILLIP A , YAMAMOTO TAKASHI
IPC分类号： C12N15/82
CPC分类号： C12N15/8286 , A01N63/02 , C07K14/195 , C07K2319/00 , Y02A40/162
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.
摘要翻译：提供了控制害虫的组成和方法。该方法涉及用编码杀虫蛋白的核酸序列转化生物体。特别地，核酸序列可用于制备具有杀虫活性的植物和微生物。因此，提供了转化的细菌，植物，植物细胞，植物组织和种子。组合物是杀虫的核酸和细菌物种的蛋白质。这些序列用于构建表达载体，用于随后转化为感兴趣的生物体，作为用于分离其他同源（或部分同源的）基因的探针。杀虫蛋白用于控制，抑制生长或杀死鳞翅目，鞘翅目，dipteran，真菌，半翅目和线虫害虫群体，并用于生产具有杀虫活性的组合物。

6. 发明申请

WO2005082077A2 NOVEL BACILLUS THURINGIENSIS CRYSTAL POLYPEPTIDES, POLYNUCLEOTIDES, AND COMPOSITIONS THEREOF 审中-公开
标题翻译：新颖的玻璃纤维水晶聚合物，聚碳酸酯及其组合物
公开(公告)号：WO2005082077A2
公开(公告)日：2005-09-09
申请号：PCT/US2005006238
申请日：2005-02-25
申请人： PIONEER HI BRED INT , BERMUDEZ ERICKA , EMIG ROBIN , MCBRIDE KEVIN , YAMAMOTO TAKASHI
发明人： BERMUDEZ ERICKA , EMIG ROBIN , MCBRIDE KEVIN , YAMAMOTO TAKASHI
IPC分类号： A01H1/00 , C07K14/325 , C12N5/04 , C12N15/82
CPC分类号： C07K14/325
摘要： The present invention provides insecticidal polypeptides related to Bacillus Cry2 polypeptides. Nucleic acids encoding the polypeptides of the invention are also provided. Methods for using the polypeptides and nucleic acids of the invention to enhance resistance of plants to insect predation are encompassed.
摘要翻译：本发明提供了与芽孢杆菌Cry2多肽相关的杀虫多肽。还提供了编码本发明多肽的核酸。包括使用本发明的多肽和核酸增强植物对昆虫捕食的抗性的方法。

7. 发明申请

WO2016061197A9 INSECTICIDAL POLYPEPTIDES HAVING IMPROVED ACTIVITY SPECTRUM AND USES THEREOF 审中-公开
标题翻译：具有改进的活性谱的杀虫多肽及其用途
公开(公告)号：WO2016061197A9
公开(公告)日：2017-05-18
申请号：PCT/US2015055491
申请日：2015-10-14
申请人： PIONEER HI-BRED INT INC
发明人： IZUMI WILCOXON MICHI , YAMAMOTO TAKASHI
IPC分类号： C07K14/325 , C12N15/32
CPC分类号： C07K14/325 , A01N37/46 , A01N63/02 , A01N65/22 , A01N65/44 , C12N15/8286 , Y02A40/162 , A01N57/16
摘要： The disclosure provides nucleic acids, and variants and fragments thereof, derived from strains of Bacillus thuringiensis encoding variant polypeptides having increased pesticidal activity against insect pests, including Lepidoptera and Coleopteran. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.
摘要翻译：本公开内容提供了源自苏云金芽孢杆菌菌株的编码变体多肽的核酸及其变体和片段，所述变体多肽对昆虫害虫（包括鳞翅目和鞘翅目）具有增加的杀虫活性。本公开的具体实施方案提供了编码杀虫蛋白的分离的核酸，杀虫组合物，DNA构建体和包含所述实施方案的核酸的转化的微生物和植物。这些组合物可用于防治害虫特别是植物害虫的方法中。

8. 发明申请

WO2014150914A8 PHI-4 POLYPEPTIDES AND METHODS FOR THEIR USE 审中-公开
标题翻译： PHI-4多肽及其使用方法
公开(公告)号：WO2014150914A8
公开(公告)日：2015-11-26
申请号：PCT/US2014024524
申请日：2014-03-12
申请人： PIONEER HI BRED INT
发明人： CONG RUTH , HOU JINGTONG , HOU ZHENGLIN , PATTEN PHILLIP A , YAMAMOTO TAKASHI
IPC分类号： C12N15/82
CPC分类号： C12N15/8286 , A01N63/02 , C07K14/195 , C07K2319/00 , Y02A40/162
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.
摘要翻译：提供了控制害虫的组成和方法。该方法涉及用编码杀虫蛋白的核酸序列转化生物体。特别地，核酸序列可用于制备具有杀虫活性的植物和微生物。因此，提供了转化的细菌，植物，植物细胞，植物组织和种子。组合物是杀虫的核酸和细菌物种的蛋白质。这些序列用于构建表达载体，用于随后转化为感兴趣的生物体，作为用于分离其他同源（或部分同源的）基因的探针。杀虫蛋白用于控制，抑制生长或杀死鳞翅目，鞘翅目，dipteran，真菌，半翅目和线虫害虫种群，并用于生产具有杀虫活性的组合物。

9. 发明公开

EP2971000A4 PHI-4 POLYPEPTIDES AND METHODS FOR THEIR USE 审中-公开
标题翻译： PHI-4多肽及其使用方法
公开(公告)号：EP2971000A4
公开(公告)日：2016-11-23
申请号：EP14768504
申请日：2014-03-12
申请人： PIONEER HI BRED INT
发明人： CONG RUTH , HOU JINGTONG , HOU ZHENGLIN , PATTEN PHILLIP A , YAMAMOTO TAKASHI
IPC分类号： C12N15/82 , A01N63/02 , C07K14/195
CPC分类号： C12N15/8286 , A01N63/02 , C07K14/195 , C07K2319/00 , Y02A40/162
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.

10. 发明公开

EP1718751A4 NOVEL BACILLUS THURINGIENSIS CRYSTAL POLYPEPTIDES, POLYNUCLEOTIDES, AND COMPOSITIONS THEREOF 有权
标题翻译：新的苏云金芽孢杆菌，KRISTALLPOLYPEPTIDE，核苷酸及其组合物
公开(公告)号：EP1718751A4
公开(公告)日：2007-06-06
申请号：EP05723907
申请日：2005-02-25
申请人： PIONEER HI BRED INT
发明人： BERMUDEZ ERICKA , EMIG ROBIN , MCBRIDE KEVIN , YAMAMOTO TAKASHI
IPC分类号： C12N15/32 , A01H1/00 , A01H5/00 , C07K14/325 , C12N5/04 , C12N15/63 , C12N15/82 , C12P21/02
CPC分类号： C07K14/325

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