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    • 1. 发明申请
    • BIOMEDICAL SIGNAL MORPHOLOGY ANALYSIS METHOD
    • 生物医学信号分析方法
    • WO2008065432A1
    • 2008-06-05
    • PCT/GB2007/004617
    • 2007-11-30
    • OXFORD BIOSIGNALS LIMITEDTARASSENKO, LionelPATTERSON, AlanSTRACHAN, Iain, Guy
    • TARASSENKO, LionelPATTERSON, AlanSTRACHAN, Iain, Guy
    • A61B5/04
    • A61B5/0452A61B5/0468A61B5/0476A61B5/1455A61B5/7267
    • A way of quantifying the shape of an ECG waveform is disclosed by detecting the JT segment using two Hidden Markov Models and calculating the analytic signal of the JT segment. Parameters calculated from the analytic signal are used as shape descriptors for the JT segment. The shape descriptors may be displayed in a dimensionality-reduced mapping. Templates representing characteristic shapes can be produced by finding cluster centres in the shape descriptor space, and the novelty of new waveforms can be quantified by comparing the position in shape descriptor space of new shape descriptors to a predefined normal training set or to previously encountered waveforms. Novel shape descriptors can be used to retrieve the corresponding waveforms, and templates of such novel shapes can be created by averaging such waveforms, using dynamic time warping to allow for variations in heart rate. The templates can be manually segmented and the manual segmentation propagated back into other waveforms having similar shape descriptors.
    • 通过使用两个隐马尔可夫模型检测JT段并计算JT段的分析信号来公开量化ECG波形形状的方法。 从分析信号计算的参数用作JT段的形状描述符。 形状描述符可以被显示在维度降低的映射中。 可以通过在形状描述符空间中发现聚类中心来产生表征特征形状的模板,并且可以通过将新形状描述符的形状描述符空间中的位置与预定义的正常训练集或先前遇到的波形进行比较来量化新波形的新颖性。 可以使用新颖的形状描述符来检索相应的波形,并且可以通过使用动态时间扭曲来平均这样的波形来创建这种新形状的模板,以允许心率的变化。 模板可以手动分割,手动分割传播回具有类似形状描述符的其他波形。