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1. 发明申请

WO2008065432A1 BIOMEDICAL SIGNAL MORPHOLOGY ANALYSIS METHOD 审中-公开
标题翻译：生物医学信号分析方法
公开(公告)号：WO2008065432A1
公开(公告)日：2008-06-05
申请号：PCT/GB2007/004617
申请日：2007-11-30
申请人： OXFORD BIOSIGNALS LIMITED , TARASSENKO, Lionel , PATTERSON, Alan , STRACHAN, Iain, Guy
发明人： TARASSENKO, Lionel , PATTERSON, Alan , STRACHAN, Iain, Guy
IPC分类号： A61B5/04
CPC分类号： A61B5/0452 , A61B5/0468 , A61B5/0476 , A61B5/1455 , A61B5/7267
摘要： A way of quantifying the shape of an ECG waveform is disclosed by detecting the JT segment using two Hidden Markov Models and calculating the analytic signal of the JT segment. Parameters calculated from the analytic signal are used as shape descriptors for the JT segment. The shape descriptors may be displayed in a dimensionality-reduced mapping. Templates representing characteristic shapes can be produced by finding cluster centres in the shape descriptor space, and the novelty of new waveforms can be quantified by comparing the position in shape descriptor space of new shape descriptors to a predefined normal training set or to previously encountered waveforms. Novel shape descriptors can be used to retrieve the corresponding waveforms, and templates of such novel shapes can be created by averaging such waveforms, using dynamic time warping to allow for variations in heart rate. The templates can be manually segmented and the manual segmentation propagated back into other waveforms having similar shape descriptors.
摘要翻译：通过使用两个隐马尔可夫模型检测JT段并计算JT段的分析信号来公开量化ECG波形形状的方法。从分析信号计算的参数用作JT段的形状描述符。形状描述符可以被显示在维度降低的映射中。可以通过在形状描述符空间中发现聚类中心来产生表征特征形状的模板，并且可以通过将新形状描述符的形状描述符空间中的位置与预定义的正常训练集或先前遇到的波形进行比较来量化新波形的新颖性。可以使用新颖的形状描述符来检索相应的波形，并且可以通过使用动态时间扭曲来平均这样的波形来创建这种新形状的模板，以允许心率的变化。模板可以手动分割，手动分割传播回具有类似形状描述符的其他波形。

2. 发明申请

WO2005015326A1 SYSTEM FOR MONITORING THE WORKING CONDITION OF AN INSTALLATION 审中-公开
标题翻译：监控安装工作条件的系统
公开(公告)号：WO2005015326A1
公开(公告)日：2005-02-17
申请号：PCT/GB2004/003322
申请日：2004-08-02
申请人： OXFORD BIOSIGNALS LIMITED , POTTER, Charles , NICHOLLS, Paul
发明人： POTTER, Charles , NICHOLLS, Paul
IPC分类号： G05B17/02
CPC分类号： B61L23/041 , B61K9/08 , B61L23/044 , B61L23/045 , B61L23/047 , B61L2205/04 , G05B23/0254
摘要： A system for monitoring the condition of installation such as railways, pipelines, escalators and elevators etc. comprises a data processor which includes a plurality of separate feature detectors, each for monitoring a specific aspect of data obtained from the installation. The feature detectors include a model of normality, which may be learned from training data sets, and then compare the input signals to the model of normality to detect departures from normality.
摘要翻译：用于监测诸如铁路，管道，自动扶梯和电梯等的安装状态的系统包括数据处理器，其包括多个单独的特征检测器，每个特征检测器用于监视从安装获得的数据的特定方面。特征检测器包括正态性模型，其可以从训练数据集学习，然后将输入信号与正常模型进行比较，以检测偏离正常。

3. 发明申请

WO2011023924A1 SYSTEM MONITORING 审中-公开
标题翻译：系统监控
公开(公告)号：WO2011023924A1
公开(公告)日：2011-03-03
申请号：PCT/GB2010/001381
申请日：2010-07-21
申请人： OXFORD BIOSIGNALS LIMITED , TARASSENKO, Lionel , CLIFTON, David
发明人： TARASSENKO, Lionel , CLIFTON, David
IPC分类号： G05B23/02
CPC分类号： G05B23/0235 , G06K9/6284
摘要： A method of novelty detection for system monitoring utilises multimodal multivariate extreme value theory to set a novelty threshold based on the probability distribution of extreme values drawn from a model of the system. Extreme values are defined as the least probable of a set of values based on the system model.
摘要翻译：一种系统监控的新颖性检测方法利用多模态多变量极值理论，根据系统模型绘制的极值概率分布来设定新奇阈值。极值被定义为基于系统模型的一组值的可能性最小。

4. 发明申请

WO2010041019A2 IMPROVEMENTS IN OR RELATING TO MULTI-PARAMETER MONITORING 审中-公开
标题翻译：改进或涉及多参数监测
公开(公告)号：WO2010041019A2
公开(公告)日：2010-04-15
申请号：PCT/GB2009/002408
申请日：2009-10-09
申请人： OXFORD BIOSIGNALS LIMITED , HANN, Alistair , TARASSENKO, Lionel
发明人： HANN, Alistair , TARASSENKO, Lionel
IPC分类号： G06F19/00 , G06F17/00 , G06F17/10 , G06F17/17 , G06F17/18
CPC分类号： G06K9/6284 , A61B5/02055 , A61B5/021 , A61B5/0245 , A61B5/0816 , A61B5/145 , A61B5/6843 , A61B2560/0276 , G06F19/00 , G06F19/36 , G06K9/00536 , G16H50/70

5. 发明申请

WO2003038649A1 IMPROVEMENTS IN OR RELATING TO PHYSIOLOGICAL MONITORING 审中-公开
标题翻译：改善或与生理监测有关
公开(公告)号：WO2003038649A1
公开(公告)日：2003-05-08
申请号：PCT/GB2002/004874
申请日：2002-10-30
申请人： OXFORD BIOSIGNALS LIMITED , POTTER, Charles, David, Ogilvy , McGROGAN, Nicholas
发明人： POTTER, Charles, David, Ogilvy , McGROGAN, Nicholas
IPC分类号： G06F17/00
CPC分类号： A61B5/0496 , A61B5/0476 , A61B5/048 , A61B5/4812 , A61B5/4815 , A61B5/7264 , A61B5/7267
摘要： Sleep or vigilance analysis is perfomed by use of a trained artificial neural network on electro-oculogram signals. Either a left side or right side EOG signal may be used, referenced to the nearby mastoid site, the nape of the neck or another quiet site. The use of the EOG signal allows REM sleep to be distinguished from light sleep. The use of only one channel of data means that only a small number of electrodes need to be used and thus the device can be provided as a self-contained compact portable unit. The device may also provide a sleep stage type sensitive alarm clock.
摘要翻译：睡眠或警惕性分析是通过使用训练有素的人造神经网络对电眼图信号进行的。可以使用左侧或右侧EOG信号，参考附近的乳突部位，颈部的颈部或另一个安静的部位。使用EOG信号可以将REM睡眠与轻度睡眠区分开来。仅使用一个通道的数据意味着仅需要使用少量的电极，因此该设备可以作为独立的小型便携式设备来提供。该装置还可以提供睡眠阶段型敏感的闹钟。

6. 发明申请

WO2008065412A3 IMPROVED CONTROL CIRCUIT AND APPARATUS FOR NEGATIVE PRESSURE WOUND TREATMENT 审中-公开
公开(公告)号：WO2008065412A3
公开(公告)日：2008-06-05
申请号：PCT/GB2007/004593
申请日：2007-11-30
申请人： OXFORD BIOSIGNALS LIMITED , TARASSENKO, Lionel , PATTERSON, Alan , STRACHAN, Iain, Guy
发明人： TARASSENKO, Lionel , PATTERSON, Alan , STRACHAN, Iain, Guy
IPC分类号： A61B5/0452 , G06F17/00
摘要： A method of analysing biomedical signals, for example electrocardiograms, by using a Hidden Markov Model for subsections of the signal. In the case of an electrocardiogram two Hidden Markov Models are used to detect respectively the start and end of the QT interval. The relationship between the QT interval and heart rate can be computed and a contemporaneous value for the slope of this relationship can be obtained by calculating the QT/RR relationship for all of the beats in a sliding time window based on the current beat. Portions of electrocardiograms taken on different days can efficiently and accurately be compared by selecting time windows of the ECGs at the same time of day, and looking for similar beats in those time windows.

7. 发明申请

WO2003090623A1 PERFORMANCE TESTING AND VIGILANCE MONITORING 审中-公开
标题翻译：性能测试和VIGILANCE监测
公开(公告)号：WO2003090623A1
公开(公告)日：2003-11-06
申请号：PCT/GB2003/001773
申请日：2003-04-25
申请人： OXFORD BIOSIGNALS LIMITED , GEORGE, Alastair, William , TARASSENKO, Lionel
发明人： GEORGE, Alastair, William , TARASSENKO, Lionel
IPC分类号： A61B5/16
CPC分类号： A61B5/162 , A61B5/7264
摘要： A method and apparatus for measuring the psychomotor performance, in particular vigilance, of a subject by requiring the subject to press a button in response to regular dim illumination of an LED. The intervals between button presses are monitored and used to derive a continuous measure of performance/vigilance. The EEG of the subject is continuously monitored during the test and changes in the spectral content of the EEG are correlated with changes in performance/vigilance. The EEG data and performance data are used to train an artificial neural network, which can be used in a vigilance monitor which provides an indication of the vigilance of a subject when provided only with the EEG of the subject.
摘要翻译：一种用于通过要求受试者响应于LED的规则昏暗照明按压按钮来测量对象的精神运动性能（特别是警觉性）的方法和装置。按钮按压之间的间隔被监视并用于导出持续的性能/警惕度量。在测试过程中持续监测受试者的脑电图，脑电图的频谱含量变化与性能/警惕性的变化相关。 EEG数据和性能数据用于训练人造神经网络，该神经网络可用于警惕性监视器中，该监视器仅在被提供给受试者的脑电图时提供受试者的警惕性。

8. 发明申请

WO2009127799A1 METHOD AND APPARATUS FOR MEASURING BREATHING RATE 审中-公开
标题翻译：测量呼吸频率的方法和装置
公开(公告)号：WO2009127799A1
公开(公告)日：2009-10-22
申请号：PCT/GB2009/000428
申请日：2009-02-18
申请人： OXFORD BIOSIGNALS LIMITED , TARASSENKO, Lionel , FLEMING, Susannah , CLIFTON, David, Andrew
发明人： TARASSENKO, Lionel , FLEMING, Susannah , CLIFTON, David, Andrew
IPC分类号： A61B5/0452 , A61B5/08 , A61B5/0205
CPC分类号： A61B5/0816 , A61B5/0456
摘要： A method and apparatus for measuring the breathing rate from the electrocardiograph signal (ECG) by measuring the frequency of modulation of the R-R intervals using auto-regressive modelling. The R peaks are detected using a standard QRS detection technique and the R-R intervals are measured to produce a time series of values. These are resampled evenly and the resulting series is windowed in overlapping windows of typically 30 seconds' length, overlapping by 25 seconds, to obtain discrete sections which are AR modelled using an all- pole auto-regressive (AR) model. The AR model allows identification of the dominant frequencies in the signal and the pole corresponding to the breathing rate is identified- by considering its magnitude and the breathing rate it represents. Each 30 second window gives a breathing rate estimate and use of successive windows displaced by 5 seconds results in a breathing rate estimate every 5 seconds. The time series of breathing rate estimates can be Kalman filtered to reject measurements which have a large change in magnitude or represent a large change in breathing rate. The measurements may also be fused with measurements from another sensor.
摘要翻译：一种通过使用自回归模型测量R-R间隔的调制频率从心电图仪信号（ECG）测量呼吸频率的方法和装置。使用标准QRS检测技术检测R峰，并测量R-R间隔以产生时间序列值。这些被均匀重采样，并且所得到的系列在通常30秒长度的重叠窗口中被窗口化，重叠25秒，以获得使用全极自回归（AR）模型进行AR建模的离散部分。 AR模型允许识别信号中的主要频率，并且通过考虑其表示的大小和呼吸速率来识别与呼吸率相对应的极点。每30秒窗口给出呼吸速率估计值，并且使用连续的窗口移位5秒会导致呼吸速率估计每5秒钟。呼吸速率估计的时间序列可以被卡尔曼滤波以排除具有大幅度变化或表示呼吸速率的大变化的测量。测量结果也可以与来自另一传感器的测量结合。

9. 发明申请

WO2009016334A1 METHOD AND APPARATUS FOR MEASURING BREATHING RATE 审中-公开
标题翻译：测量呼吸频率的方法和装置
公开(公告)号：WO2009016334A1
公开(公告)日：2009-02-05
申请号：PCT/GB2008/002043
申请日：2008-06-13
申请人： OXFORD BIOSIGNALS LIMITED , TARASSENKO, Lionel , FLEMING, Susannah
发明人： TARASSENKO, Lionel , FLEMING, Susannah
IPC分类号： A61B5/024 , A61B5/08 , A61B5/00 , G01R23/16
CPC分类号： A61B5/0816 , A61B5/02416 , A61B5/1455
摘要： A method and apparatus for measuring the breathing rate from the photoplethysmogram signal (PPG) by using auto-regressive modelling of the signal. The PPG signal is windowed in overlapping windows of typically 30 seconds' length, overlapping by 25 seconds, to obtain discrete sections of the signal and each section is low-pass filtered, downsampled and detrended iand then AR modelled using an all-pole auto-regressive (AR) model. The AR model allows identification of the dominant frequencies in the signal and the pole corresponding to the breathing rate is identified by considering its magnitude and the breathing rate it represents. Each 30 second window gives a breathing rate estimate and use of successive windows displaced by 5 seconds results in a breathing rate estimate every 5 seconds. The time series of breathing rate estimates can be Kalman filtered to reject measurements which have a large change in magnitude or represent a large change in breathing rate. The measurements may also be fused with measurements from another sensor.
摘要翻译：一种通过使用信号的自回归建模来测量来自光电体积描记图信号（PPG）的呼吸速率的方法和装置。 PPG信号在通常长度为30秒，重叠25秒的重叠窗口中开窗，以获得信号的离散部分，并且每个部分被低通滤波，下采样和去极化，然后使用全极自动对数模拟，回归（AR）模型。 AR模型允许识别信号中的主要频率，并且通过考虑其表示的大小和呼吸速率来识别与呼吸速率相对应的极点。每30秒窗口给出呼吸速率估计值，并且使用连续的窗口移位5秒会导致呼吸速率估计每5秒钟。呼吸速率估计的时间序列可以被卡尔曼滤波以排除具有大幅度变化或表示呼吸速率的大变化的测量。测量结果也可以与来自另一传感器的测量结合。

10. 发明申请

WO2004090486A1 METHOD AND SYSTEM FOR ANALYSING TACHOMETER AND VIBRATION DATA FROM AN APPARATUS HAVING ONE OR MORE ROTARY COMPONENTS 审中-公开
标题翻译：用于从具有一个或多个旋转部件的装置分析测速仪和振动数据的方法和系统
公开(公告)号：WO2004090486A1
公开(公告)日：2004-10-21
申请号：PCT/GB2004/001575
申请日：2004-04-08
申请人： OXFORD BIOSIGNALS LIMITED , KING, Dennis , ASTLEY, Ken , TARASSENKO, Lionel , ANUZIS, Paul , HAYTON, Paul , KING, Stephen
发明人： KING, Dennis , ASTLEY, Ken , TARASSENKO, Lionel , ANUZIS, Paul , HAYTON, Paul , KING, Stephen
IPC分类号： G01H1/00
CPC分类号： G01H1/003
摘要： A method of analysing tachometer and vibration response data from an apparatus having one or more rotary components is provided. The method comprises the steps of: providing vibration response data and corresponding tachometer data from the apparatus for a period over which a rotary component of the apparatus varies in rotational speed, the tachometer data being for that component; repeatedly performing at intervals throughout the period the sub-steps of: determining a forcing frequency of the component from the tachometer data and a corresponding vibration response frequency of the apparatus from the vibration response data, comparing the forcing and vibration response frequencies to determine the relative phase difference between the frequencies, and determining the corresponding amplitude of the vibration response from the vibration response data; and plotting the relative phase differences and vibration amplitudes on a polar diagram. The plot trajectory is characteristic of the behaviour of the apparatus over the period.
摘要翻译：提供了一种从具有一个或多个旋转部件的装置分析转速计和振动响应数据的方法。该方法包括以下步骤：提供来自装置的振动响应数据和相应的转速计数据，其中装置的旋转部件以其旋转速度变化的时间段，转速计数据用于该部件; 在整个时期间隔间隔重复执行以下子步骤：根据振动响应数据确定来自转速表数据的部件的强制频率和相应的振动响应频率，比较强制和振动响应频率以确定相对频率之间的相位差，并根据振动响应数据确定振动响应的对应振幅; 并绘制极坐标图上的相对相位差和振幅。剧情轨迹是该时期设备行为的特征。

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