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1. 发明申请

WO2008038046A1 ION FILTER 审中-公开
标题翻译：离子过滤器
公开(公告)号：WO2008038046A1
公开(公告)日：2008-04-03
申请号：PCT/GB2007/050581
申请日：2007-09-25
申请人： OWLSTONE LTD , HART, Matthew , KOEHL, Andrew
发明人： HART, Matthew , KOEHL, Andrew
IPC分类号： G01N27/64 , H01J49/42
CPC分类号： H01J49/061 , G01N27/622 , H01J49/0018 , H01J49/421
摘要： An ion filter (10) for use in ion mobility spectrometry is described, together with a method for manufacturing the filter. The filter (10) is manufactured by removing portions from a monolithic structure to form a pair of electrodes which remain mechanically connected. The connecting portion (22) provides sufficient electrical impedance between the electrodes to effectively electrically separate the electrodes. The connecting portion may be doped or chemically modified to obtain a desired impedance, or this may be obtained through appropriate selection of physical dimensions.
摘要翻译：与用于制造过滤器的方法一起描述了用于离子迁移谱的离子过滤器（10）。过滤器（10）通过从单片结构中移除部分以形成保持机械连接的一对电极来制造。连接部分（22）在电极之间提供足够的电阻抗以有效地电分离电极。连接部分可以被掺杂或化学修饰以获得期望的阻抗，或者这可以通过适当选择物理尺寸来获得。

2. 发明申请

WO2007034239A2 ION PUMP 审中-公开
标题翻译：离子泵
公开(公告)号：WO2007034239A2
公开(公告)日：2007-03-29
申请号：PCT/GB2006/050294
申请日：2006-09-19
申请人： OWLSTONE LTD , ALONSO, David Ruiz , KOEHL, Andrew , BOYLE, Paul , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
发明人： ALONSO, David Ruiz , KOEHL, Andrew , BOYLE, Paul , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
IPC分类号： H01J49/42
CPC分类号： G01N27/624
摘要： The invention provides an ion pump to be used for selectively transferring ionised molecules across a barrier from a first volume to a second volume. The pump comprises an ion gate or filter separating the two volumes, the filter comprising at least one ion channel extending between the first and second spaces, the channel defined by a plurality of conductive layers separated along the length of the channel by at least one non-conductive layer; the device further comprising control means for applying an electric potential to the conductive layers such that the conductive layers act as electrodes. Other aspects of the invention relate to methods for selectively transferring ions.
摘要翻译：本发明提供了一种用于选择性地将电离分子从第一体积迁移到阻挡层的离子泵至第二体积。所述泵包括分离两个体积的离子浇口或过滤器，所述过滤器包括在所述第一和第二空间之间延伸的至少一个离子通道，所述离子通道由沿所述通道长度分开的多个导电层限定至少一个非导电层，导电层; 该装置还包括用于向导电层施加电势的控制装置，使得导电层用作电极。本发明的其它方面涉及选择性转移离子的方法。

3. 发明申请

WO2009136190A1 SENSOR 审中-公开
标题翻译：传感器
公开(公告)号：WO2009136190A1
公开(公告)日：2009-11-12
申请号：PCT/GB2009/050466
申请日：2009-05-06
申请人： OWLSTONE LTD. , KOEHL, Andrew
发明人： KOEHL, Andrew
IPC分类号： G01N27/66
CPC分类号： G01N27/66
摘要： A method and sensor for monitoring chemical species in a gas flow are described. An ionised sample of gas is passed through a flow channel, with a DC electric field applied transverse to the longitudinal axis of the channel. Any electric current produced by the ion flow is measured, with variations in the current being indicative of a change in composition of the gas flow. In certain embodiments, the DC field may be varied over time, to sweep the field voltage. The detected current against field voltage graph may be taken as a profile of a particular gas composition. Variations in the profile again are indicative of a change in gas composition.
摘要翻译：描述了用于监测气流中的化学物质的方法和传感器。气体的电离样品通过流动通道，其中DC电场横向于通道的纵向轴线施加。测量由离子流产生的任何电流，其中电流的变化表示气流的组成变化。在某些实施例中，DC场可以随时间变化，以扫描场电压。检测到的电场电压图可以视为特定气体组成的轮廓。轮廓的变化再次表明气体成分的变化。

4. 发明申请

WO2006013396A3 ION MOBILITY SPECTROMETER 审中-公开
公开(公告)号：WO2006013396A3
公开(公告)日：2006-02-09
申请号：PCT/GB2005/050124
申请日：2005-08-02
申请人： OWLSTONE LTD , BOYLE, Paul , KOEHL, Andrew , ALONSO, David Ruiz
发明人： BOYLE, Paul , KOEHL, Andrew , ALONSO, David Ruiz
IPC分类号： H01J49/42 , B01D59/44 , G01N27/64
摘要： An ion mobility spectrometer is described having an ion filter in the form of at least one ion channel having a plurality of electrodes. A time-varying electric potential applied to the conductive layers allows the filler to selectively admit ion species. The electric potential has a drive and a transverse component, and in preferred embodiments each of the electrodes is involved in generating a component of both the drive and transverse fields. The device may be used without a drift gas flow, Microfabrication techniques are described for producing microscale spectrometers, as are various uses of the spectrometer.

5. 发明申请

WO2008054376A2 NANOSTRUCTURES CONTAINING INORGANIC NANOTUBES AND METHODS OF THEIR SYNTHESIS AND USE 审中-公开
标题翻译：含有无机纳米粒子的纳米结构及其合成与使用方法
公开(公告)号：WO2008054376A2
公开(公告)日：2008-05-08
申请号：PCT/US2006/038561
申请日：2006-09-29
申请人： OWLSTONE NANOTECH, INC. , BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
发明人： BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
IPC分类号： G01N30/96
CPC分类号： G01N30/6095 , B01J20/28007 , B82Y30/00
摘要： The invention relates to novel micro- or nanostructures incorporating nanotubes, wherein nanotubes are synthesized or grown directly in or on components of a micro- or nano-structure. In a particular embodiment, the invention relates to methods of synthesizing or growing nanotubes in a gas chromatography column and their use in portable gas chromatography devices.
摘要翻译：本发明涉及纳入纳米管的新型微结构或纳米结构，其中纳米管直接在微结构或纳米结构的组分中或组分上合成或生长。在一个具体实施方案中，本发明涉及在气相色谱柱中合成或生长纳米管的方法及其在便携式气相色谱装置中的应用。

6. 发明申请

WO2007044379A3 COMPACT IONIZATION SOURCE 审中-公开
公开(公告)号：WO2007044379A3
公开(公告)日：2007-04-19
申请号：PCT/US2006/038744
申请日：2006-10-02
申请人： OWLSTONE NANOTECH, INC. , RUSH, Martyn , BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , PARRIS, Russell , WILKS, Ashley
发明人： RUSH, Martyn , BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , PARRIS, Russell , WILKS, Ashley
IPC分类号： H01J27/02
摘要： A compact ionization source includes first and second electrodes, each having a plurality of fingers that are interdigitated with each other. The spacing between the first and second electrode, preferably less than 1 mm, creates a large electric field when a potential is applied across the first and second electrodes. The large electric field creates an ionization volume between the fingers of the first and second electrode and ionizes a portion of the molecules occupying the ionization volume. The interdigitated fingers of the first and second electrodes allow for a narrow gap separating the electrodes while presenting a large flow area for ionizing molecules for downstream analysis.

7. 发明申请

WO2007035825A2 ION GATE 审中-公开
标题翻译：离子门
公开(公告)号：WO2007035825A2
公开(公告)日：2007-03-29
申请号：PCT/US2006/036687
申请日：2006-09-19
申请人： OWLSTONE NANOTECH, INC. , RUIZ-ALONSO, David , KOEHL, Andrew , BOYLE, Paul , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
发明人： RUIZ-ALONSO, David , KOEHL, Andrew , BOYLE, Paul , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
IPC分类号： H01J49/40
CPC分类号： H01J49/42
摘要： An ion gate is disposed between a first volume occupied by a first carrier gas and ions of the first carrier gas and a second volume occupied by a second carrier gas. The ion gate includes at least one channel connecting the first volume to the second volume, a first electrode disposed on an inlet surface of the ion gate facing the first volume, and a second electrode disposed on an outlet surface of the ion gate facing the second volume. Ions are transported from the first volume to the second volume through the channel under an electric field produced by the first and second electrode.
摘要翻译：离子门设置在由第一载气占据的第一体积和第一载气的离子与由第二载气占据的第二体积之间。离子门包括将第一体积连接到第二体积的至少一个通道，设置在离子门的面向第一体积的入口表面上的第一电极以及设置在离子门的面向第二体积的第二电极卷。在由第一和第二电极产生的电场作用下，离子通过通道从第一体积转移到第二体积。

8. 发明申请

WO2007050475A3 ION DRIVE AND ODOR EMITTER 审中-公开
公开(公告)号：WO2007050475A3
公开(公告)日：2007-05-03
申请号：PCT/US2006/041178
申请日：2006-10-20
申请人： OWLSTONE NANOTECH, INC. , PARRIS, Russell , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , BOYLE, Paul , WILKS, Ashley
发明人： PARRIS, Russell , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , BOYLE, Paul , WILKS, Ashley
IPC分类号： H01J49/00
摘要： The present invention relates to an ion drive for selectively isolating an analyte of interest and methods of use thereof. The ion drive includes a substrate with channels therethrough, a conductive material coating on the bottom and top of the substrate, a top electrical lead connected to the conductive material coating covering the top of the substrate, and a bottom electrical lead connected to the conductive material coating covering the bottom of the substrate. The invention further relates to an odor emitter which is made up of an ion drive mounted towards the top of a vessel.

9. 发明申请

WO2007041551A3 3D MINIATURE PRECONCENTRATOR AND INLET SAMPLE HEATER 审中-公开
公开(公告)号：WO2007041551A3
公开(公告)日：2007-04-12
申请号：PCT/US2006/038565
申请日：2006-09-29
申请人： OWLSTONE NANOTECH, INC. , BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
发明人： BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
IPC分类号： B01D53/02
摘要： The present invention relates to a three dimensional preconcentrator and inlet heater. The preconcentrator consists of a substrate with passageways, a conductive material coated to the top and the bottom of the substrate and an adsorbent coating covering the entire substrate. This substrate is suspended in a holding frame by a connecting bridge. The preconcentrator may also include a resistor and a proportional-integral-differential controller. The device may be used inline with a detector and can be retrofitted to existing devices. An array of preconcentrators may also be formed. The invention also relates to methods of use of the preconcentrator and methods of manufacture. A method of use includes contacting an analyte and a preconcentrator, allowing the analyte to adsorb to the preconcentrator and then desorbing the analyte. A method of manufacture involves applying the adsorbent coating by misted chemical deposition.

10. 发明申请

WO2007041550A3 NANOSTRUCTURES CONTAINING CARBON NANOTUBES AND METHODS OF THEIR SYNTHESIS AND USE 审中-公开
公开(公告)号：WO2007041550A3
公开(公告)日：2007-04-12
申请号：PCT/US2006/038564
申请日：2006-09-29
申请人： OWLSTONE NANOTECH, INC. , BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
发明人： BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
IPC分类号： B01D53/02
摘要： The invention relates to novel micro- or nanostructures incorporating nanotubes, wherein nanotubes are synthesized or grown directly in or on components of a micro- or nano-structure. In a particular embodiment, the invention relates to methods of synthesizing or growing nanotubes in a gas chromatography column and their use in portable gas chromatography devices.

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