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1. 发明申请

WO2008054376A2 NANOSTRUCTURES CONTAINING INORGANIC NANOTUBES AND METHODS OF THEIR SYNTHESIS AND USE 审中-公开
标题翻译：含有无机纳米粒子的纳米结构及其合成与使用方法
公开(公告)号：WO2008054376A2
公开(公告)日：2008-05-08
申请号：PCT/US2006/038561
申请日：2006-09-29
申请人： OWLSTONE NANOTECH, INC. , BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
发明人： BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
IPC分类号： G01N30/96
CPC分类号： G01N30/6095 , B01J20/28007 , B82Y30/00
摘要： The invention relates to novel micro- or nanostructures incorporating nanotubes, wherein nanotubes are synthesized or grown directly in or on components of a micro- or nano-structure. In a particular embodiment, the invention relates to methods of synthesizing or growing nanotubes in a gas chromatography column and their use in portable gas chromatography devices.
摘要翻译：本发明涉及纳入纳米管的新型微结构或纳米结构，其中纳米管直接在微结构或纳米结构的组分中或组分上合成或生长。在一个具体实施方案中，本发明涉及在气相色谱柱中合成或生长纳米管的方法及其在便携式气相色谱装置中的应用。

2. 发明申请

WO2007044379A3 COMPACT IONIZATION SOURCE 审中-公开
公开(公告)号：WO2007044379A3
公开(公告)日：2007-04-19
申请号：PCT/US2006/038744
申请日：2006-10-02
申请人： OWLSTONE NANOTECH, INC. , RUSH, Martyn , BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , PARRIS, Russell , WILKS, Ashley
发明人： RUSH, Martyn , BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , PARRIS, Russell , WILKS, Ashley
IPC分类号： H01J27/02
摘要： A compact ionization source includes first and second electrodes, each having a plurality of fingers that are interdigitated with each other. The spacing between the first and second electrode, preferably less than 1 mm, creates a large electric field when a potential is applied across the first and second electrodes. The large electric field creates an ionization volume between the fingers of the first and second electrode and ionizes a portion of the molecules occupying the ionization volume. The interdigitated fingers of the first and second electrodes allow for a narrow gap separating the electrodes while presenting a large flow area for ionizing molecules for downstream analysis.

3. 发明申请

WO2007035825A2 ION GATE 审中-公开
标题翻译：离子门
公开(公告)号：WO2007035825A2
公开(公告)日：2007-03-29
申请号：PCT/US2006/036687
申请日：2006-09-19
申请人： OWLSTONE NANOTECH, INC. , RUIZ-ALONSO, David , KOEHL, Andrew , BOYLE, Paul , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
发明人： RUIZ-ALONSO, David , KOEHL, Andrew , BOYLE, Paul , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
IPC分类号： H01J49/40
CPC分类号： H01J49/42
摘要： An ion gate is disposed between a first volume occupied by a first carrier gas and ions of the first carrier gas and a second volume occupied by a second carrier gas. The ion gate includes at least one channel connecting the first volume to the second volume, a first electrode disposed on an inlet surface of the ion gate facing the first volume, and a second electrode disposed on an outlet surface of the ion gate facing the second volume. Ions are transported from the first volume to the second volume through the channel under an electric field produced by the first and second electrode.
摘要翻译：离子门设置在由第一载气占据的第一体积和第一载气的离子与由第二载气占据的第二体积之间。离子门包括将第一体积连接到第二体积的至少一个通道，设置在离子门的面向第一体积的入口表面上的第一电极以及设置在离子门的面向第二体积的第二电极卷。在由第一和第二电极产生的电场作用下，离子通过通道从第一体积转移到第二体积。

4. 发明申请

WO2007050475A3 ION DRIVE AND ODOR EMITTER 审中-公开
公开(公告)号：WO2007050475A3
公开(公告)日：2007-05-03
申请号：PCT/US2006/041178
申请日：2006-10-20
申请人： OWLSTONE NANOTECH, INC. , PARRIS, Russell , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , BOYLE, Paul , WILKS, Ashley
发明人： PARRIS, Russell , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , BOYLE, Paul , WILKS, Ashley
IPC分类号： H01J49/00
摘要： The present invention relates to an ion drive for selectively isolating an analyte of interest and methods of use thereof. The ion drive includes a substrate with channels therethrough, a conductive material coating on the bottom and top of the substrate, a top electrical lead connected to the conductive material coating covering the top of the substrate, and a bottom electrical lead connected to the conductive material coating covering the bottom of the substrate. The invention further relates to an odor emitter which is made up of an ion drive mounted towards the top of a vessel.

5. 发明申请

WO2007041551A3 3D MINIATURE PRECONCENTRATOR AND INLET SAMPLE HEATER 审中-公开
公开(公告)号：WO2007041551A3
公开(公告)日：2007-04-12
申请号：PCT/US2006/038565
申请日：2006-09-29
申请人： OWLSTONE NANOTECH, INC. , BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
发明人： BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
IPC分类号： B01D53/02
摘要： The present invention relates to a three dimensional preconcentrator and inlet heater. The preconcentrator consists of a substrate with passageways, a conductive material coated to the top and the bottom of the substrate and an adsorbent coating covering the entire substrate. This substrate is suspended in a holding frame by a connecting bridge. The preconcentrator may also include a resistor and a proportional-integral-differential controller. The device may be used inline with a detector and can be retrofitted to existing devices. An array of preconcentrators may also be formed. The invention also relates to methods of use of the preconcentrator and methods of manufacture. A method of use includes contacting an analyte and a preconcentrator, allowing the analyte to adsorb to the preconcentrator and then desorbing the analyte. A method of manufacture involves applying the adsorbent coating by misted chemical deposition.

6. 发明申请

WO2007041550A3 NANOSTRUCTURES CONTAINING CARBON NANOTUBES AND METHODS OF THEIR SYNTHESIS AND USE 审中-公开
公开(公告)号：WO2007041550A3
公开(公告)日：2007-04-12
申请号：PCT/US2006/038564
申请日：2006-09-29
申请人： OWLSTONE NANOTECH, INC. , BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
发明人： BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
IPC分类号： B01D53/02
摘要： The invention relates to novel micro- or nanostructures incorporating nanotubes, wherein nanotubes are synthesized or grown directly in or on components of a micro- or nano-structure. In a particular embodiment, the invention relates to methods of synthesizing or growing nanotubes in a gas chromatography column and their use in portable gas chromatography devices.

7. 发明申请

WO2008094299A2 SMART FAIMS SENSOR 审中-公开
标题翻译： SMART FAIMS传感器
公开(公告)号：WO2008094299A2
公开(公告)日：2008-08-07
申请号：PCT/US2007/073717
申请日：2007-07-17
申请人： OWLSTONE NANOTECH, INC. , BOYLE, Paul , RUSH, Martyn , RUIZ-ALONSO, David , KOEHL, Andrew , PARRIS, Russell , WILKS, Ashley
发明人： BOYLE, Paul , RUSH, Martyn , RUIZ-ALONSO, David , KOEHL, Andrew , PARRIS, Russell , WILKS, Ashley
CPC分类号： G01N27/624
摘要： A smart FAIMS sensor system and method includes an array of two or more FAIMS sensors and a controller configured to control independently each of the FAIMS sensors in the array. In a preferred embodiment, the sensor array is normally operated with one FAIMS sensor operating in a high sensitivity mode while the remaining sensors are turned off. When the high sensitivity FAIMS sensor detects a possible event, each of the remaining sensors is turned on in sequence to confirm the possible event. Each of the remaining sensors is operated in a different selectivity mode that together forms a characteristic signature of a target analyte. The characteristic signature is more robust against false positives and an alarm is registered only when all remaining sensors confirm the possible event detected by the high sensitivity sensor. In another embodiment, a smart FAIMS sensor system and method includes a 2/2-electrode filter that pumps the ions through the system and separates the ionic species, a detector for collecting the separated ions and generating a detector signal in response to the collected ions, and a controller configured to change the operating parameters of the system in response to changes in the sensor's environment detected by the sensor. The ability to dynamically change the operating parameters of the sensor enables the sensor to maintain high sensitivity to environmental threats while decreasing the incidences of false positive events.
摘要翻译：智能FAIMS传感器系统和方法包括两个或更多个FAIMS传感器的阵列和被配置为独立地控制阵列中的每个FAIMS传感器的控制器。在优选实施例中，传感器阵列通常以一个在高灵敏度模式下运行的FAIMS传感器工作，而剩下的传感器被关闭。当高灵敏度FAIMS传感器检测到可能的事件时，依次打开每个剩余的传感器以确认可能的事件。每个剩余的传感器以不同的选择性模式操作，共同形成目标分析物的特征。只有当所有剩余传感器确认高灵敏度传感器检测到的可能事件时，特征识别才能抵抗误报，而且只能报警。在另一个实施例中，智能FAIMS传感器系统和方法包括：2/2电极过滤器，其通过系统泵送离子并分离离子物质;用于收集分离离子的检测器，并响应于所收集的离子产生检测器信号以及控制器，被配置为响应于由传感器检测到的传感器的环境的变化而改变系统的操作参数。动态改变传感器工作参数的能力使传感器能够保持对环境威胁的高度敏感性，同时减少假阳性事件的发生率。

8. 发明申请

WO2008048247A2 METHODS OF SYNTHESIS OF NANOTUBES AND USES THEREOF 审中-公开
标题翻译：纳米管的合成方法及其用途
公开(公告)号：WO2008048247A2
公开(公告)日：2008-04-24
申请号：PCT/US2006/038566
申请日：2006-09-29
申请人： OWLSTONE NANOTECH, INC. , BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
发明人： BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
IPC分类号： H01L21/20
CPC分类号： B01J23/70 , B01J20/205 , B01J20/28007 , B01J20/281 , B01J37/0238 , B82B3/00 , B82Y30/00 , B82Y40/00 , C01B32/162 , C01B2202/02 , C23C16/0281 , Y02P20/135
摘要： The invention relates to novel methods of incorporating nanotubes for use in micro- or nano-devices. The invention further relates to incorporating nanotubes in micro or nano- devices and particularly synthesizing or growing nanotubes directly in or on components of a micro- or nano-device. In a particular embodiment, the invention relates to methods of synthesizing or growing nanotubes in a gas chromatography column and their use in portable gas chromatography devices.
摘要翻译：本发明涉及纳入用于微纳米器件的纳米管的新方法。本发明进一步涉及将纳米管纳入微纳米器件，特别是在微纳米器件的组件中或其组件上直接合成或生长纳米管。在一个具体实施方案中，本发明涉及在气相色谱柱中合成或生长纳米管的方法及其在便携式气相色谱装置中的应用。

9. 发明申请

WO2007034239A2 ION PUMP 审中-公开
标题翻译：离子泵
公开(公告)号：WO2007034239A2
公开(公告)日：2007-03-29
申请号：PCT/GB2006/050294
申请日：2006-09-19
申请人： OWLSTONE LTD , ALONSO, David Ruiz , KOEHL, Andrew , BOYLE, Paul , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
发明人： ALONSO, David Ruiz , KOEHL, Andrew , BOYLE, Paul , RUSH, Martyn , PARRIS, Russell , WILKS, Ashley
IPC分类号： H01J49/42
CPC分类号： G01N27/624
摘要： The invention provides an ion pump to be used for selectively transferring ionised molecules across a barrier from a first volume to a second volume. The pump comprises an ion gate or filter separating the two volumes, the filter comprising at least one ion channel extending between the first and second spaces, the channel defined by a plurality of conductive layers separated along the length of the channel by at least one non-conductive layer; the device further comprising control means for applying an electric potential to the conductive layers such that the conductive layers act as electrodes. Other aspects of the invention relate to methods for selectively transferring ions.
摘要翻译：本发明提供了一种用于选择性地将电离分子从第一体积迁移到阻挡层的离子泵至第二体积。所述泵包括分离两个体积的离子浇口或过滤器，所述过滤器包括在所述第一和第二空间之间延伸的至少一个离子通道，所述离子通道由沿所述通道长度分开的多个导电层限定至少一个非导电层，导电层; 该装置还包括用于向导电层施加电势的控制装置，使得导电层用作电极。本发明的其它方面涉及选择性转移离子的方法。

10. 发明公开

EP1934999A2 COMPACT IONIZATION SOURCE 审中-公开
标题翻译： COMPACT电离
公开(公告)号：EP1934999A2
公开(公告)日：2008-06-25
申请号：EP06816188.4
申请日：2006-10-02
申请人： Owlstone Nanotech, Inc.
发明人： RUSH, Martyn , BOYLE, Paul , RUIZ-ALONSO, David , KOEHL, Andrew , PARRIS, Russell , WILKS, Ashley
IPC分类号： H01J27/02
CPC分类号： H01T19/04 , H01T19/00
摘要： A compact ionization source includes first and second electrodes, each having a plurality of fingers that are interdigitated with each other. The spacing between the first and second electrode, preferably less than 1 mm, creates a large electric field when a potential is applied across the first and second electrodes. The large electric field creates an ionization volume between the fingers of the first and second electrode and ionizes a portion of the molecules occupying the ionization volume. The interdigitated fingers of the first and second electrodes allow for a narrow gap separating the electrodes while presenting a large flow area for ionizing molecules for downstream analysis.

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