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1. 发明申请

WO2017196306A1 LASER EYE SURGERY SYSTEMS AND METHODS OF TREATING VITREOUS AND OCULAR FLOATERS 审中-公开
标题翻译：激光眼外科系统和治疗精细浮肿和眼球浮肿的方法
公开(公告)号：WO2017196306A1
公开(公告)日：2017-11-16
申请号：PCT/US2016/031673
申请日：2016-05-10
申请人： OPTIMEDICA CORPORATION
发明人： SCHUELE, Georg , GOODING, Phillip, H. , VANKOV, Alexander , WILTBERGER, Michael, W.
IPC分类号： A61F9/008
摘要： A laser eye surgery system used to treat vitreous bodies includes a laser source, a ranging subsystem, an integrated optical subsystem, and a patient interface assembly. The laser source produces a treatment beam that includes a plurality of laser pulses. The ranging subsystem produces a source beam used to locate one or more structures of an eye. In some embodiments, the ranging subsystem includes an optical coherence tomography (OCT) pickoff assembly that includes a first optical wedge and a second optical wedge separated from the first optical wedge. The OCT pickoff assembly is configured to divide an OCT source beam into a sample beam and a reference beam. The integrated optical subsystem is used to scan the treatment beam and the sample beam. In other embodiments, Purkinje imaging, Scheimpflug imaging, confocal or nonlinear optical microscopy, ultrasound, stereo imaging, fluorescence imaging, or other medical imaging technique may be used.
摘要翻译：用于治疗玻璃体的激光眼科手术系统包括激光源，测距子系统，集成光学子系统和患者接口组件。激光源产生包括多个激光脉冲的治疗光束。测距子系统产生用于定位眼睛的一个或多个结构的源光束。在一些实施例中，测距子系统包括光学相干断层扫描（OCT）拾取组件，其包括第一光楔和与第一光楔分离的第二光楔。 OCT拾取组件被配置为将OCT源光束分成样本光束和参考光束。集成光学子系统用于扫描治疗光束和样品光束。在其他实施例中，可以使用浦肯野成像，舍姆普弗鲁克成像，共焦或非线性光学显微镜术，超声波，立体成像，荧光成像或其他医学成像技术。

2. 发明申请

WO2014158615A1 LASER EYE SURGERY SYSTEM 审中-公开
标题翻译：激光眼部手术系统
公开(公告)号：WO2014158615A1
公开(公告)日：2014-10-02
申请号：PCT/US2014/018752
申请日：2014-02-26
申请人： OPTIMEDICA CORPORATION , SCHUELE, Georg , GOODING, Phillip
发明人： SCHUELE, Georg , GOODING, Phillip
IPC分类号： A61F9/008 , A61B3/10
CPC分类号： A61F9/00804 , A61B3/1025 , A61B3/14 , A61F9/008 , A61F9/00802 , A61F9/00812 , A61F9/00836 , A61F2009/00846 , A61F2009/00855 , A61F2009/00868 , A61F2009/00872 , A61F2009/00889 , A61F2009/00897
摘要： An imaging system includes an eye interface device, a scanning assembly, a beam source, a free-floating mechanism, and a detection assembly. The eye interface device interfaces with an eye. The scanning assembly supports the eye interface device and scans a focal point of an electromagnetic radiation beam within the eye. The beam source generates the electromagnetic radiation beam. The free-floating mechanism supports the scanning assembly and accommodates movement of the eye and provides a variable optical path for the electronic radiation beam and a portion of the electronic radiation beam reflected from the focal point location. The variable optical path is disposed between the beam source and the scanner and has an optical path length that varies to accommodate movement of the eye. The detection assembly generates a signal indicative of intensity of a portion of the electromagnetic radiation beam reflected from the focal point location.
摘要翻译：成像系统包括眼睛接口装置，扫描组件，束源，自由浮动机构和检测组件。眼睛接口设备与眼睛接口。扫描组件支持眼睛接口装置并扫描眼睛内的电磁辐射束的焦点。光束源产生电磁辐射束。自由浮动机构支持扫描组件并且适应眼睛的运动，并且为电子辐射束提供可变的光路以及从焦点位置反射的电子辐射束的一部分。可变光路设置在光束源和扫描仪之间，并且具有变化的光路长度以适应眼睛的移动。检测组件产生指示从焦点位置反射的电磁辐射束的一部分的强度的信号。

3. 发明申请

WO2017209772A1 FREE FLOATING PATIENT INTERFACE FOR LASER SURGERY SYSTEM 审中-公开
标题翻译：用于激光手术系统的自由浮动患者接口
公开(公告)号：WO2017209772A1
公开(公告)日：2017-12-07
申请号：PCT/US2016/035905
申请日：2016-06-03
申请人： OPTIMEDICA CORPORATION
发明人： GOODING, Phillip H. , SCHUELE, Georg
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F2009/00897
摘要： Systems and methods here may be used to support a laser eye surgery device, including a base assembly mounted to an optical scanning assembly via, a horizontal x axis bearing, a horizontal y axis bearing, and a vertical z axis bearing, mounted on the base assembly, configured to limit movement of the optical scanning assembly in an x axis, y axis and z axis respectively, relative to the base assembly, a vertical z axis spring, configured to counteract the forces of gravity on the optical scanning assembly in the z axis, and, mirrors mounted on the base assembly and positioned to reflect an energy beam into the optical scanning assembly no matter where the optical scanning assembly is located on the x axis bearing, the y axis bearing and the z axis bearing.
摘要翻译：这里的系统和方法可用于支持激光眼科手术装置，其包括通过水平x轴承，水平y轴承和垂直轴安装到光学扫描组件上的基座组件 z轴承，其安装在基座组件上，被配置为相对于基座组件分别限制光学扫描组件在x轴，y轴和z轴上的移动;垂直z轴弹簧，其被配置为抵消重力在z轴上的光学扫描组件上以及安装在基座组件上并定位成将能量束反射到光学扫描组件中的镜子，无论光学扫描组件位于x轴承上的何处，y轴承和 z轴承。

4. 发明申请

WO2016061454A1 CORNEAL TOPOGRAPHY MEASUREMENTS AND FIDUCIAL MARK INCISIONS IN LASER SURGICAL PROCEDURES 审中-公开
标题翻译：激光手术过程中的角膜测量和FIDUCAL MARK INCISIONS
公开(公告)号：WO2016061454A1
公开(公告)日：2016-04-21
申请号：PCT/US2015/055936
申请日：2015-10-16
申请人： OPTIMEDICA CORPORATION
发明人： SRINIVASAN, Rajeshwari , GOLDA, Jeffrey, A. , GONZALEZ, Javier, G. , SCOTT, David, D. , DEWEY, David, A. , BAREKET, Noah , SCHUELE, Georg
IPC分类号： A61F9/008
CPC分类号： A61F9/00825 , A61F2009/00865 , A61F2009/0087 , A61F2009/00872 , A61F2009/00882
摘要： A method of cataract surgery in an eye of a patient includes identifying a feature selected from the group consisting of an axis, a meridian, and a structure of an eye by corneal topography and forming fiducial mark incisions with a laser beam along the axis, meridian or structure in the cornea outside the optical zone of the eye. A laser cataract surgery system a laser source, a topography measurement system, an integrated optical subsystem, and a processor in operable communication with the laser source, corneal topography subsystem and the integrated optical system. The processor includes a tangible non- volatile computer readable medium comprising instructions to determine one of an axis, meridian and structure of an eye of the patient based on the measurements received from topography measurement system, and direct the treatment beam so as to incise radial fiducial mark incisions.
摘要翻译：在患者眼睛中的白内障手术的方法包括通过角膜形貌识别选自由轴，子午线和眼睛结构组成的组的特征，并且沿着轴线形成具有激光束的基准标记切口，子午线或在眼睛的光学区域外的角膜中的结构。激光白内障手术系统，激光源，地形测量系统，集成光学子系统和与激光源，角膜地形子系统和集成光学系统可操作地通信的处理器。处理器包括有形的非易失性计算机可读介质，其包括用于基于从地形测量系统接收的测量值来确定患者的眼睛的轴线，子午线和结构之一的指令，并且引导治疗束以切割径向基准标记切口。

5. 发明申请

WO2011085274A1 SYSTEM FOR MODIFYING EYE TISSUE AND INTRAOCULAR LENSES 审中-公开
标题翻译：用于修饰眼睛组织和眼科镜片的系统
公开(公告)号：WO2011085274A1
公开(公告)日：2011-07-14
申请号：PCT/US2011/020610
申请日：2011-01-07
申请人： OPTIMEDICA CORPORATION , SCHUELE, Georg , ANDERSEN, Dan
发明人： SCHUELE, Georg , ANDERSEN, Dan
IPC分类号： A61F9/008
CPC分类号： A61F9/008 , A61F9/00812 , A61F9/00827 , A61F9/00834 , A61F2009/00842 , A61F2009/00853 , A61F2009/0087 , A61F2009/00872 , A61F2009/00889
摘要： As shown in the drawings for purposes of illustration, a method and system for making physical modifications to intraocular targets is described. In varying embodiments, the method and system described herein provide many advantages over the current standard of care. Specifically, linear absorption facilitated photodecomposition and linear absorption facilitated plasma generation to modify intraocular tissues and synthetic intraocular lenses.
摘要翻译：如图所示，为了说明的目的，描述了一种用于对眼内靶标进行物理修改的方法和系统。在不同的实施例中，本文描述的方法和系统提供了超过目前护理标准的许多优点。具体地，线性吸收促进光分解和线性吸收促进等离子体产生以修饰眼内组织和合成人工晶状体。

6. 发明申请

WO2016153571A1 MULTIPLE DEPTH OPTICAL COHERENCE TOMOGRAPHY SYSTEM AND METHOD AND LASER EYE SURGERY SYSTEM INCORPORATING THE SAME 审中-公开
标题翻译：多个深度光学相干系统和方法以及激光眼部手术系统
公开(公告)号：WO2016153571A1
公开(公告)日：2016-09-29
申请号：PCT/US2015/065998
申请日：2015-12-16
申请人： OPTIMEDICA CORPORATION
发明人： SCHUELE, Georg
IPC分类号： A61B3/10
CPC分类号： A61B3/102 , A61B3/1005 , A61B3/117 , A61B3/1225 , A61F9/008 , A61F2009/00851 , A61F2009/00863 , A61F2009/0087
摘要： An OCT system for imaging multiple depth positions includes a light source, a sample arm and two or more reference arms. The sample arm propagates light to the object and directs object return light having a first return light beam from a first position and a second return light beam from a second position, the second return light having a dispersion level higher than the first return light beam by a dispersion difference amount. The first and second reference arms produce light beams having substantially the same dispersion as the first and second return light beams, respectively. The optical pathway combines all of the object return light and the reference light beams. An OCT detector measures the resulting interferogram. Imaging information is obtained for both the first position and the second position based on the dispersion difference amount.
摘要翻译：用于对多个深度位置成像的OCT系统包括光源，样本臂和两个或更多个参考臂。样品臂将光传播到物体，并将来自第一位置的第一返回光束的物体返回光和来自第二位置的第二返回光束引导，第二返回光具有比第一返回光束高的色散电平，色散差异量。第一和第二参考臂分别产生具有与第一和第二返回光束基本相同的色散的光束。光学路径结合了所有物体返回光和参考光束。 OCT检测器测量所得到的干涉图。基于色散差量获得第一位置和第二位置两者的成像信息。

7. 发明申请

WO2014172621A9 CORNEAL TOPOGRAPHY MEASUREMENT AND ALIGNMENT OF CORNEAL SURGICAL PROCEDURES 审中-公开
标题翻译：角膜地形图的测量和角膜手术的调整
公开(公告)号：WO2014172621A9
公开(公告)日：2014-10-23
申请号：PCT/US2014/034628
申请日：2014-04-18
申请人： OPTIMEDICA CORPORATION , SCOTT, David, D. , GONZALEZ, Javier , DEWEY, David , BAREKET, Noah , SCHUELE, Georg
发明人： SCOTT, David, D. , GONZALEZ, Javier , DEWEY, David , BAREKET, Noah , SCHUELE, Georg
IPC分类号： A61F9/009 , A61B3/107
摘要： Methods and apparatus are configures to measure an eye without contacting the eye with a patient interface, and these measurements are used to determine alignment and placement of the incisions when the patient interface contacts the eye. The pre-contact locations of one or more structures of the eye can be used to determine corresponding post-contact locations of the one or more optical structures of the eye when the patient interface has contacted the eye, such that the laser incisions are placed at locations that promote normal vision of the eye. The incisions are positioned in relation to the pre-contact optical structures of the eye, such as an astigmatic treatment axis, nodal points of the eye, and visual axis of the eye.
摘要翻译：方法和设备被配置成在患者接口不接触眼睛的情况下测量眼睛，并且这些测量被用于确定当患者接口接触眼睛时切口的对准和放置。当患者接口已经接触眼睛时，眼睛的一个或多个结构的预接触位置可以用于确定眼睛的一个或多个光学结构的相应的接触后位置，使得激光切口位于促进眼睛正常视力的位置。切口相对于眼睛的预接触光学结构定位，例如散光治疗轴，眼睛的节点以及眼睛的视轴。

8. 发明申请

WO2014149832A1 MICROFEMTOTOMY METHODS AND SYSTEMS 审中-公开
标题翻译：微观方法和系统
公开(公告)号：WO2014149832A1
公开(公告)日：2014-09-25
申请号：PCT/US2014/021119
申请日：2014-03-06
申请人： OPTIMEDICA CORPORATION , SCHUELE, Georg , STEVENS, Julian , ANDERSEN, Dan, E.
发明人： SCHUELE, Georg , STEVENS, Julian , ANDERSEN, Dan, E.
IPC分类号： A61F9/008 , A61F9/00 , A61F2/16
CPC分类号： A61F9/00754 , A61F2/16 , A61F9/0017 , A61F9/00834 , A61F2009/00851 , A61F2009/0087 , A61F2009/00889
摘要： Methods and systems for performing laser-assisted surgery on an eye form one or more small anchoring capsulotomies in the lens capsule of the eye. The one or more anchoring capsulotomies are configured to accommodate corresponding anchoring features of an intraocular lens and/or to accommodate one or more drug-eluting members. A method for performing laser-assisted eye surgery on an eye having a lens capsule includes forming an anchoring capsulotomy in the lens capsule and coupling an anchoring feature of the intraocular lens with the anchoring capsulotomy. The anchoring capsulotomy is formed by using a laser to incise the lens capsule. The anchoring feature can protrude transverse to a surface of the intraocular lens that interfaces with the lens capsule adjacent to the anchoring capsulotomy.
摘要翻译：用于在眼睛上进行激光辅助手术的方法和系统在眼睛的晶状体囊中形成一个或多个小型锚固囊切开术。一个或多个锚定囊切开术被配置为适应眼内透镜的相应锚固特征和/或容纳一个或多个药物洗脱部件。在具有透镜胶囊的眼睛上执行激光辅助眼睛手术的方法包括在镜片胶囊中形成锚定囊切开术并将眼内透镜的锚定特征与锚定囊切开术联接。通过使用激光切割镜片胶囊来形成锚定囊切开术。锚定特征可以横向于眼镜片的与固定囊切开术相邻的透镜胶囊的表面突出。

9. 发明申请

WO2018144644A1 METHODS AND SYSTEMS FOR LASER OPHTHALMIC SURGERY THAT PROVIDE FOR IRIS EXPOSURES BELOW A PREDETERMINED EXPOSURE LIMIT 审中-公开
公开(公告)号：WO2018144644A1
公开(公告)日：2018-08-09
申请号：PCT/US2018/016307
申请日：2018-01-31
申请人： OPTIMEDICA CORPORATION
发明人： SCHUELE, Georg , DEWEY, David A. , GONZALEZ, Javier G. , VANKOV, Alexander
IPC分类号： A61F9/008
摘要： A laser surgical method for performing a corneal incision while maintaining iris exposure below a predetermined exposure limit includes : determining an initial iris exposure based on an initial treatment scan, determining whether the initial iris exposure is less than the predetermined exposure limit; generating a revised treatment scan comprising one or more treatment scan modifying elements when the initial iris exposure is greater than the predetermined exposure limit, and scanning the focal zone of a pulsed laser beam according to the revised treatment scan, thereby performing the corneal incision, wherein the one or more treatment scan modifying elements causes the iris exposure to be smaller than the predetermined exposure limit.

10. 发明申请

WO2018052418A1 FREE FLOATING PATIENT INTERFACE FOR LASER SURGERY SYSTEM 审中-公开
标题翻译：用于激光手术系统的自由浮动患者接口
公开(公告)号：WO2018052418A1
公开(公告)日：2018-03-22
申请号：PCT/US2016/051776
申请日：2016-09-14
申请人： OPTIMEDICA CORPORATION
发明人： SCHUELE, Georg , GOODING, Phillip H. , ANGELEY, David , WANG, Zhao
IPC分类号： A61F9/009 , A61F9/008
摘要： Systems and methods here may be used to support a femtosecond laser eye surgery system including utilizing a floating head and/or patient support to maintain alignment of the system with a patient using feedback loops of force sensors in a patient interface. In some examples, the floating head and/or patient support may counteract movements detected in the force sensors. In some example embodiments, a ranging subsystem may detect and compensate for different arrangements of the floating head assembly using a ranging sample beam.
摘要翻译：这里的系统和方法可用于支持飞秒激光眼科手术系统，包括利用浮动头部和/或患者支撑件以使用反馈回路中的力传感器来维持系统与患者的对准患者接口。在一些示例中，浮动头部和/或患者支撑可以抵消在力传感器中检测到的运动。在一些示例实施例中，测距子系统可以使用测距样本光束检测并补偿浮动头组件的不同布置。

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