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1. 发明授权

US08068987B2 Method and system for profiling biological systems 有权
标题翻译：生物系统分析方法和系统
公开(公告)号：US08068987B2
公开(公告)日：2011-11-29
申请号：US10218880
申请日：2002-08-13
申请人： Noubar B. Afeyan , Jan van der Greef , Frederick E. Regnier , Aram S. Adourian , Eric K. Neumann , Matej Oresic , Elwin Robbert Verheij
发明人： Noubar B. Afeyan , Jan van der Greef , Frederick E. Regnier , Aram S. Adourian , Eric K. Neumann , Matej Oresic , Elwin Robbert Verheij
IPC分类号： G01N33/48 , G01N33/50
CPC分类号： G06F19/24 , Y10T436/24
摘要： The present invention provides methods and systems for developing profiles of a biological system based on the discernment of similarities, differences, and/or correlations between biomolecular components of a plurality of biological samples. Preferably, the method comprises utilizing hierarchical multivariate analysis of spectrometric data at one or more levels of correlation.
摘要翻译：本发明提供了基于对多个生物样品的生物分子组分之间的相似性，差异和/或相关性的鉴别来开发生物系统的分布的方法和系统。优选地，该方法包括在一个或多个相关级别上利用光谱数据的分层多变量分析。

2. 发明申请

US20110010099A1 Correlation Analysis of Biological Systems 审中-公开
标题翻译：生物系统相关分析
公开(公告)号：US20110010099A1
公开(公告)日：2011-01-13
申请号：US11992257
申请日：2006-09-19
申请人： Aram S Adourian , Matej Oresic , Doris Damian , Eric K. Neumann , Thomas Plasterer , Ezra Jennings
发明人： Aram S Adourian , Matej Oresic , Doris Damian , Eric K. Neumann , Thomas Plasterer , Ezra Jennings
IPC分类号： G06F19/00 , G01N33/48
CPC分类号： G16B5/00
摘要： The present teachings relate to gaining insight into biological states, e.g., disease states or drugged states, by gathering, integrating, and combining biomolecular data. More particularly, the present teachings relate to methods and systems for profiling a state of a biological system, finding accessible biomarkers representative of the state of a biological system, and deriving insights into the biochemistry of a biological system for therapeutic, diagnostic, prognostic and other purposes.
摘要翻译：本教导涉及通过收集，整合和组合生物分子数据来了解生物状态，例如疾病状态或药物状态。更具体地，本教导涉及用于分析生物系统的状态，找到代表生物系统的状态的可及性生物标志物的方法和系统，以及用于治疗，诊断，预后等的生物系统的生物化学的见解目的

3. 发明申请

US20120131484A1 COHORT-SELECTABLE FACETED DISPLAY 审中-公开
标题翻译： COHORT-SELECTABLE FACETED显示
公开(公告)号：US20120131484A1
公开(公告)日：2012-05-24
申请号：US13165508
申请日：2011-06-21
申请人： Eric K. Neumann , Keith G. Boyce
发明人： Eric K. Neumann , Keith G. Boyce
IPC分类号： G06F3/048
CPC分类号： G06F16/338 , G06F16/36 , G06F16/367
摘要： A computer-implemented display of semantically characterized information can include cohort indicators representing a group of one or more specified cohort parameters applied in such a way so as to filter a dataset comprising RDF structured data items. Each cohort indicator can be associated with a set of RDF structured semantic predicates. At least one selectable facet value indicator can be included that represents one or more specified value parameters each being associated with a RDF structured semantic object. The one or more specified value parameters can be applicable to the dataset in such a way so as to enable additional filtering and modification of one or more of the resulting cohort groups of information. A visual display of filtered information can be included which results from separately applying, against the dataset, each group of one or more specified cohort parameters represented by each cohort indicator.
摘要翻译：计算机实现的语义特征化信息的显示可以包括表示以这样的方式应用的一个或多个指定队列参数的组的队列指示符，以便过滤包括RDF结构化数据项的数据集。每个队列指示符可以与一组RDF结构化语义谓词相关联。可以包括表示一个或多个指定值参数的至少一个可选择面值指示符，每个参数值参数与RDF结构化语义对象相关联。一个或多个指定的值参数可以以这样的方式应用于数据集，以便能够对所得到的一组或多个信息组进行过滤和修改。可以包括过滤的信息的视觉显示，其由针对数据集分别应用于由每个队列指示符表示的一个或多个指定的队列参数的每组组成。

4. 发明授权

US07865534B2 System, method and apparatus for assembling and mining life science data 有权
标题翻译：组装和开采生命科学数据的系统，方法和装置
公开(公告)号：US07865534B2
公开(公告)日：2011-01-04
申请号：US10644582
申请日：2003-08-20
申请人： D. Navin Chandra , Fatima Chandra, legal representative , Dexter R. Pratt , Eric K. Neumann , Keith O. Elliston , Justin Sun , Ted M. Slater
发明人： D. Navin Chandra , Dexter R. Pratt , Eric K. Neumann , Keith O. Elliston , Justin Sun , Ted M. Slater
IPC分类号： G06F17/30
CPC分类号： G05B19/00 , G06F19/00 , G06F19/18 , G06F19/24 , G06F19/26 , G06F19/28 , G16H50/70
摘要： Method and system for managing and evaluating life science data. Life Science data is placed in a knowledge base, that may be used for a variety of analysis tasks. Creating a knowledge base from the life science data involves generating two or more nodes indicative of life science data, assigning to one or more pairs of nodes a representation descriptor that corresponds to a relationship between the nodes, and assembling the nodes and the relationship descriptor into a database, such that at least one of the nodes is joined to another node by a representation descriptor. In some embodiments, the representation descriptor includes a case frame that describes the relationships between elements of life science data.
摘要翻译：管理和评估生命科学数据的方法和系统。生命科学数据放在知识库中，可用于各种分析任务。从生命科学数据创建知识库涉及生成指示生命科学数据的两个或多个节点，向一个或多个对节点分配与节点之间的关系对应的表示描述符，并将节点和关系描述符组合成数据库，使得至少一个节点通过表示描述符连接到另一个节点。在一些实施例中，表示描述符包括描述生命科学数据元素之间的关系的情况帧。

5. 发明申请

US20110270893A1 System, method and apparatus for assembling and mining life science data 审中-公开
公开(公告)号：US20110270893A1
公开(公告)日：2011-11-03
申请号：US12982651
申请日：2010-12-30
申请人： D. Navin Chandra , Dexter R. Pratt , Eric K. Neumann , Keith O. Elliston , Justin Sun , Ted M. Slater
发明人： D. Navin Chandra , Dexter R. Pratt , Eric K. Neumann , Keith O. Elliston , Justin Sun , Ted M. Slater
IPC分类号： G06F17/30
CPC分类号： G05B19/00 , G16B20/00 , G16B40/00 , G16B45/00 , G16B50/00 , G16H50/70
摘要： Method and system for managing and evaluating life science data. Life Science data is placed in a knowledge base, that may be used for a variety of analysis tasks. Creating a knowledge base from the life science data involves generating two or more nodes indicative of life science data, assigning to one or more pairs of nodes a representation descriptor that corresponds to a relationship between the nodes, and assembling the nodes and the relationship descriptor into a database, such that at least one of the nodes is joined to another node by a representation descriptor. In some embodiments, the representation descriptor includes a case frame that describes the relationships between elements of life science data.

6. 发明授权

US06175872B1 Collaborative environment for syncronizing audio from remote devices 失效
标题翻译：用于从远程设备同步音频的协作环境
公开(公告)号：US06175872B1
公开(公告)日：2001-01-16
申请号：US08990122
申请日：1997-12-12
申请人： Eric K. Neumann , David J. Reider
发明人： Eric K. Neumann , David J. Reider
IPC分类号： G06F1516
CPC分类号： G10H1/0066 , H04L67/38
摘要： Apparatus and software systems are disclosed that allow real-time interactive playing of musicians each at remote sites from each other. The remote sites are interconnected over a local communications network or a wide area network like the Internet. The apparatus is connected to music synthesizers that accept streams of MIDI data for playing, or generate streams of MIDI data by playing. The streams of MIDI data are bundled by a MIDI management system into transfer control protocol packets, such that the packets of MIDI data may be transferred over the communications network as or within the transfer control packets. In addition, the networked, remote computer systems are synchronized to a standard clock which is appended to the MIDI data packets, and additionally, the network delay is calculated and also appended to the MIDI data packets. In this manner the local musician can receive the MIDI data packets from the remote sites where musicians are playing and in real-time play with them. The present invention allows other data bases of music to be interrogated and the music therein retrieved for local use, storing and/or editing. The invention allows the received MIDI data from remote sites to be precisely time positioned within the local memory as if on separate tracks like a multi-track tape recorder for later or real-time playing and/or editing.
摘要翻译：公开了装置和软件系统，其允许每个在彼此远程站点的音乐家的实时交互式播放。远程站点通过本地通信网络或像互联网这样的广域网互联。该装置连接到接收MIDI数据流的音乐合成器，或通过播放产生MIDI数据流。 MIDI数据流由MIDI管理系统捆绑成传输控制协议分组，使得MIDI数据的分组可以在传输控制分组中或在传输控制分组内通过通信网络传送。此外，联网的远程计算机系统被同步到附加到MIDI数据分组的标准时钟，并且还计算网络延迟并且也附加到MIDI数据分组。以这种方式，本地音乐家可以从音乐家正在播放的远程站点接收MIDI数据包，并与其进行实时播放。本发明允许询问音乐的其他数据库，并且其中的音乐被检索用于本地使用，存储和/或编辑。本发明允许来自远程站点的接收到的MIDI数据被精确地定时在本地存储器中，如同在诸如多轨磁带录音机的分开的轨道上一样，用于稍后或实时播放和/或编辑。

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