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1. 发明专利

JP2009160389A Patch package structure 有权
标题翻译： PATCH包装结构
公开(公告)号：JP2009160389A
公开(公告)日：2009-07-23
申请号：JP2008316628
申请日：2008-12-12
申请人： Nitto Denko Corp , Sasaki Chemical Co Ltd , 佐々木化学薬品株式会社 , 日東電工株式会社
发明人： IWAO YOSHIHIRO , HANATANI AKINORI , SEKIYA JUNICHI , AKEMI HITOSHI
IPC分类号： A61F13/02 , A61K9/70
CPC分类号： A61L15/24 , C08L33/20
摘要： PROBLEM TO BE SOLVED: To provide a patch package structure comprising a patch with an adhesive layer including an organic liquid component and a package storing the patch, capable of stably retaining a physiologically active component of the stored patch. SOLUTION: The patch package structure comprises the patch 1 with the adhesive layer including the organic liquid component and the package 51 storing the patch. The package 51 includes a first package material 11, which includes an acrylonitrile resin layer 12, a moisture absorbent layer 13 disposed on the acrylonitrile resin layer 12, and a moisture impermeable layer 14 disposed on the moisture absorbent layer 13. The acrylonitrile resin layer 12 is located on the proximal side of the patch 1. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种补片包装结构，其包括具有包括有机液体组分的粘合剂层和存储该贴片的包装的贴剂，能够稳定地保留所存储的贴剂的生理活性成分。解决方案：贴剂包装结构包括贴剂1，粘合剂层包括有机液体组分和储存贴剂的包装51。包装51包括第一包装材料11，其包括丙烯腈树脂层12，设置在丙烯腈树脂层12上的吸湿层13和设置在吸湿层13上的不透水层14.丙烯腈树脂层12 位于贴片1的近侧。版权所有（C）2009，JPO＆INPIT

2. 发明专利

JP2009160388A Patch package structure 有权
标题翻译： PATCH包装结构
公开(公告)号：JP2009160388A
公开(公告)日：2009-07-23
申请号：JP2008316625
申请日：2008-12-12
申请人： Nitto Denko Corp , Sasaki Chemical Co Ltd , 佐々木化学薬品株式会社 , 日東電工株式会社
发明人： IWAO YOSHIHIRO , HANATANI AKINORI , SEKIYA JUNICHI , AKEMI HITOSHI
IPC分类号： A61F13/02 , A61K9/70 , A61L15/16 , A61P17/02
CPC分类号： A61F15/001 , A61L15/24 , C08L33/20
摘要： PROBLEM TO BE SOLVED: To provide a patch package structure capable of stably retaining a physiologically active component of a patch while the patch is stored. SOLUTION: The patch package structure comprises the patch 1 and a package 51 for storing the patch 1. The patch 1 includes a support body 2 and an adhesive layer 3 disposed at least on one side of the support body 2. The package 51 includes a first package material 11, which includes an acrylonitrile resin layer 12, a moisture absorbent layer 13 disposed on the acrylonitrile resin layer 12, and a moisture impermeable layer 14 disposed on the moisture absorbent layer 13. The acrylonitrile resin layer 12 is located on the proximal side of the patch 1. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种补片包装结构，其能够在保存贴剂的同时稳定地保持贴剂的生理活性成分。解决方案：贴片包装结构包括贴片1和用于存储贴片1的包装51.贴片1包括支撑体2和设置在支撑体2的至少一侧的粘合剂层3.包装 51包括第一包装材料11，其包括丙烯腈树脂层12，设置在丙烯腈树脂层12上的吸湿层13和设置在吸湿层13上的不透水层14.丙烯腈树脂层12位于在补丁1的近侧。版权所有（C）2009，JPO＆INPIT

3. 发明专利

JP2014087704A Patch, and patch preparation 审中-公开
标题翻译： PATCH和配对准备
公开(公告)号：JP2014087704A
公开(公告)日：2014-05-15
申请号：JP2014020319
申请日：2014-02-05
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： TERASHI SACHIKO , HANATANI AKINORI , AKEMI HITOSHI , IWAO YOSHIHIRO
IPC分类号： A61F13/02 , A61K9/70
CPC分类号： A61K9/703 , A61F2013/00651 , A61K9/7061
摘要： PROBLEM TO BE SOLVED: To provide a lowly stretchable patch and a patch preparation, which can be continuously patched for a long time without any separation and any falling undesirably in the worst case due to various factors while being applied to a skin.SOLUTION: A lowly stretchable patch and a patch preparation having an adhesive layer on one side of a substrate are characterized: in that the ratio P(W/S) of the total length W (mm) of the curve portion of a planar outer shape of a patch to the total length S (mm) of the straight line portion of the planar outer shape of the patch is 1.22 or less; and in that the radius R (mm) of the arc of the case, in which the curved portion is made similar to an arc, 0.5 mm or more.
摘要翻译：要解决的问题：提供一种低伸缩性贴剂和贴剂制剂，其可以在施用于皮肤时由于各种因素而在长时间内连续修补而没有任何分离，并且在最坏的情况下由于各种因素而不希望地下降。解决方案：A 低伸缩性贴剂和在基材一侧具有粘合剂层的贴片制剂的特征在于：贴片的平面外形曲线部分的总长度W（mm）的比率P（W / S）贴片平面外形的直线部分的总长S（mm）为1.22以下; 并且其中弯曲部分类似于电弧的壳体的弧的半径R（mm）为0.5mm或更大。

4. 发明专利

JP2005087463A Fur removing sheet 有权
标题翻译： FUR拆卸表
公开(公告)号：JP2005087463A
公开(公告)日：2005-04-07
申请号：JP2003324508
申请日：2003-09-17
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： SAITO JUNICHI , ITO MASAAKI , HANATANI AKINORI
IPC分类号： A47K7/02 , A61B17/24
摘要： PROBLEM TO BE SOLVED: To provide a fur removing sheet capable of removing excessive fur on the tongue, hardly causing nausea at the time of use, reducing stimulation to the upper jaw and hardly causing problems in terms of sanitation. SOLUTION: The fur removing sheet is a layered product having a synthetic resin film on the outermost layer of one surface and having nonwoven fabric composed of synthetic fibers with a triangular cross section on the outermost layer of the other surface, the static friction coefficient of the nonwoven fabric is 0.6 to 0.9, and the bending resistance of the layered product is 40mm to 150mm. In this case, it is preferable that the nonwoven fabric is formed of splittable fibers. Also, it is preferable that the splittable fibers are polypropylene and polyester splittable fibers. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：为了提供能够去除舌头上过多毛皮的毛皮去除片，在使用时几乎不引起恶心，减少对上颌的刺激并且几乎不引起卫生问题。毛皮去除片是在一个表面的最外层具有合成树脂膜的层叠体，并且在另一个表面的最外层具有由具有三角形截面的合成纤维构成的无纺布，静摩擦无纺布的系数为0.6〜0.9，层叠体的耐弯曲性为40mm〜150mm。在这种情况下，优选无纺布由可分裂纤维形成。此外，优选的是，可分裂纤维是聚丙烯和聚酯可分裂纤维。版权所有（C）2005，JPO＆NCIPI

5. 发明专利

JP2014061187A Packaging material and package structure using the same 有权
标题翻译：包装材料和包装结构使用相同
公开(公告)号：JP2014061187A
公开(公告)日：2014-04-10
申请号：JP2012208811
申请日：2012-09-21
申请人： Toyo Seikan Kaisha Ltd , 東洋製罐株式会社 , Nitto Denko Corp , 日東電工株式会社
发明人： ISHIZAKI YOICHI , OTA YOSHIHIRO , HANATANI AKINORI , SAKAMOTO SACHIKO , MUKAIHATA GO , IWAO YOSHIHIRO
IPC分类号： A61J1/00 , A61K9/70 , A61K31/138 , A61K45/00
CPC分类号： A61K9/7038 , A61K9/7061 , B32B7/12 , B32B15/082 , B32B15/095 , B32B27/08 , B32B27/308 , B32B27/36 , B32B27/40 , B32B2307/7244 , B32B2307/7246 , B32B2307/74 , B32B2439/80 , B65D75/30 , Y10T428/1379
摘要： PROBLEM TO BE SOLVED: To provide a packaging material that is capable of long term storage by preventing adsorption or transfer of an easily oxidizable component and an oily component in an adhesive of a patch to the packaging material, and also preventing discoloration and decrease in a drug effect due to oxidization.SOLUTION: Provided with a packaging material for a patch including: an inner layer made of polyethylene terephthalate having heat sealing properties; an oxygen-absorbing layer that includes an oxygen-absorbing resin having an unsaturated alicyclic structure as an oxygen-absorbing part; and an oxygen barrier layer made of aluminum foil as an outer layer.
摘要翻译：要解决的问题：提供一种能够通过防止粘合剂中的易氧化组分和油性组分吸附或转移到包装材料上而能够长期储存的包装材料，并且还防止变色和减少由于氧化引起的药物作用。解决方案：提供用于贴片的包装材料，包括：具有热封性的由聚对苯二甲酸乙二酯制成的内层; 氧吸收层，其包含具有不饱和脂环结构的氧吸收性树脂作为氧吸收部; 以及由铝箔制成的氧阻隔层作为外层。

6. 发明专利

JP2012255044A Control method for time discoloration of donepezil-containing adhesive preparation 有权
标题翻译：用于时间分解含二苯乙烯的粘合剂制备的控制方法
公开(公告)号：JP2012255044A
公开(公告)日：2012-12-27
申请号：JP2012222172
申请日：2012-10-04
申请人： Nitto Denko Corp , 日東電工株式会社 , Eisai R & D Management Co Ltd , エーザイ・アール・アンド・ディー・マネジメント株式会社
发明人： NISHI SUMIYO , HANATANI AKINORI , SEKIYA JUNICHI , TERASHI SACHIKO , AKEMI HITOSHI , WASHIRO TOMOKO
IPC分类号： A61K31/445 , A61K9/70 , A61K47/02 , A61K47/04 , A61K47/10 , A61K47/14 , A61K47/16 , A61K47/20 , A61K47/22 , A61K47/26 , A61P25/28
CPC分类号： A61K31/445 , A61K9/7061 , A61K31/375 , A61K33/04
摘要： PROBLEM TO BE SOLVED: To control a time discoloration in a donepezil-containing adhesive preparation.SOLUTION: An adhesive layer containing an adhesive and donepezil further contains: ascorbic acid or its metal salt or ester; isoascorbic acid or its metal salt; ethylenediaminetetraacetic acid or its metal salt; 2-mercapto benzimidazole; 3(2)-t-butyl-4-hydroxyanisole; 2, 6-die-t-butyl-4-methylphenol; tetrakis [3-(3', 5'-die-t-butyl-4'-hydroxyphenyl) propionic acid]; pentaerythritol; (±)-α-tocopherol; acetic acid (±)-α-tocopherol; rutin; hypophosphorous acid; metal salt of metabisulfite; and at least one stabilizer chosen from a group of metal salts of hydroxymethane sulfinic acid.
摘要翻译：要解决的问题：控制含有多奈哌齐的粘合剂制剂中的时间变色。溶液：含有粘合剂和多奈哌齐的粘合剂层还含有：抗坏血酸或其金属盐或酯; 异抗坏血酸或其金属盐; 乙二胺四乙酸或其金属盐; 2-巯基苯并咪唑; 3（2） - 叔丁基-4-羟基苯甲醚; 2,6-二叔丁基-4-甲基苯酚; 四[3-（3'，5'-去甲基叔丁基-4'-羟基苯基）丙酸]; 季戊四醇; （±）-α-α-生育酚; 乙酸（±）-α-生育酚; 芦丁; 次磷酸; 偏亚硫酸氢盐金属盐; 和选自羟基甲烷亚磺酸的一组金属盐中的至少一种稳定剂。版权所有（C）2013，JPO＆INPIT

7. 发明专利

JP2007153849A External preparation 有权
标题翻译：外部准备
公开(公告)号：JP2007153849A
公开(公告)日：2007-06-21
申请号：JP2005355107
申请日：2005-12-08
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： WASHIRO TOMOKO , HANATANI AKINORI
IPC分类号： A61K47/18 , A61K9/70 , A61K31/196 , A61K47/14 , A61K47/22
CPC分类号： A61K9/0014 , A61K9/7038
摘要： PROBLEM TO BE SOLVED: To provide an external preparation exhibiting excellent percutaneous absorbability of an ionic medicine.
SOLUTION: The external preparation comprises a component (a): an ionic medicine and a component (b): an ionic liquid composed of a cation and an anion. As the ionic liquid functions as a dissolution auxiliary of the ionic medicine and enhances the solubility of the medicine in the external preparation, percutaneous absorption of the ionic medicine is promoted.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：待解决的问题：提供表现出优异的离子药物的经皮吸收性的外用制剂。解决方案：外用制剂包含组分（a）：离子药物和组分（b）：由阳离子和阴离子组成的离子液体。由于离子液体作为离子药物的溶解助剂起作用，提高了药物在外用制剂中的溶解性，促进了离子药物的经皮吸收。版权所有（C）2007，JPO＆INPIT

8. 发明专利

JP2005110917A Sticking material 有权
标题翻译：贴纸
公开(公告)号：JP2005110917A
公开(公告)日：2005-04-28
申请号：JP2003348312
申请日：2003-10-07
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： SAITO JUNICHI , HANATANI AKINORI
IPC分类号： A61K9/70 , A61F13/02
摘要： PROBLEM TO BE SOLVED: To provide a sticking material for easily and safely performing a series of operations at the time of sticking it to the skin or the like.
SOLUTION: For the sticking material, a supporting layer, an adhesive material layer and a separator are laminated in this order, and the separator is divided into two areas by an L-shaped cutting line 1 for division. Of the two areas, in the L-shaped first area 3 with a recessed part, a cut line 2 from a corner part of the recessed part to the outer shape line of the separator is provided halfway and the length of the cut line 2 30-90% of the length of a line segment from the origin of the cut line 2 to the outer shape line of the separator.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供一种粘贴材料，用于在将其粘贴到皮肤等上时容易且安全地执行一系列操作。解决方案：对于粘合材料，依次层叠支撑层，粘合剂层和隔膜，并且通过用于划分的L形切割线1将隔板分成两个区域。在两个区域中，在具有凹部的L形第一区域3中，设置从分隔件的凹部的角部到外部形状线的切割线2，并且切割线2 30的长度 -90％的从切割线2的原点到分离器的外形线的线段的长度。版权所有（C）2005，JPO＆NCIPI

9. 发明专利

JP2013060395A Composition for enhancing transdermal absorption and patch preparation 有权
标题翻译：用于增强超吸收和配制的组合物
公开(公告)号：JP2013060395A
公开(公告)日：2013-04-04
申请号：JP2011200023
申请日：2011-09-13
申请人： Nitto Denko Corp , 日東電工株式会社
发明人： OKAZAKI ARIMICHI , MUKAIHATA GO , SAKAMOTO SACHIKO , HANATANI AKINORI
IPC分类号： A61K9/70 , A61K45/00 , A61K47/10 , A61K47/18
CPC分类号： A61K9/7038 , A61K9/0014 , A61K9/7084 , A61K31/405 , A61K31/41 , A61K31/422 , A61K31/565
摘要： PROBLEM TO BE SOLVED: To provide a composition for enhancing transdermal absorption which shows a sufficiently high enhancing effect on transdermal absorption of a drug, particularly, a composition for enhancing transdermal absorption which shows a sufficiently high enhancing effect on transdermal absorption of an acidic drug.SOLUTION: This invention relates to: a composition for enhancing transdermal absorption containing a 12-20C unsaturated higher alcohol and a 3-8C polyhydric alcohol; and a composition for enhancing transdermal absorption containing a 12-20C unsaturated higher alcohol, a 3-8C polyhydric alcohol and a 2-9C organic amine.
摘要翻译：待解决的问题：提供一种用于增强经皮吸收的组合物，其对药物的经皮吸收具有足够高的增强效果，特别是用于增强经皮吸收的组合物，其对于经皮吸收的透皮吸收具有足够高的增强作用酸性药物。解决方案：本发明涉及：含有12-20℃不饱和高级醇和3-8C多元醇的用于增强经皮吸收的组合物; 和含有12-20℃不饱和高级醇，3-8C多元醇和2-9C有机胺的增强经皮吸收的组合物。版权所有（C）2013，JPO＆INPIT

10. 发明专利

JP2012255043A Stabilized donepezil-containing patch preparation 有权
标题翻译：稳定的含有二苯醚的包装制剂
公开(公告)号：JP2012255043A
公开(公告)日：2012-12-27
申请号：JP2012222169
申请日：2012-10-04
申请人： Nitto Denko Corp , 日東電工株式会社 , Eisai R & D Management Co Ltd , エーザイ・アール・アンド・ディー・マネジメント株式会社
发明人： HANATANI AKINORI , SEKIYA JUNICHI , TERASHI SACHIKO , NISHI SUMIYO , WASHIRO TOMOKO , AKEMI HITOSHI
IPC分类号： A61K31/445 , A61K9/70 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/20 , A61K47/22 , A61K47/26 , A61P25/28
CPC分类号： A61K31/445 , A61K9/7053 , A61K9/7061
摘要： PROBLEM TO BE SOLVED: To provide a donepezil-containing patch preparation whereby production of donepezil-related substances in the pressure-sensitive adhesive layer is suppressed.SOLUTION: A stabilizer comprising at least one or more species selected from the group consisting of ascorbic acid, metal salts or esters thereof, isoascorbic acid or metal salts thereof, ethylenediamine tetraacetic acid or metal salts thereof, cysteine, acetylcysteine, 2-mercaptobenzimidazole, 3(2)-t-butyl-4-hydroxyanisole, 2,6-di-t-butyl-4-methylphenol, tetrakis[3-(3',5'-di-t-butyl-4'-hydroxyphenyl)propionic acid]pentaerythritol, 3-mercapto-1,2-propanediol, tocopherol acetate, rutin, quercetin, hydroquinone, metal salts of hydroxymethanesulfinic acid, metal metabisulfite salts, metal sulfite salts and metal thiosulfate salts is blended in a donepezil-containing pressure-sensitive adhesive layer provided on at least one side of a support.
摘要翻译：待解决的问题：提供一种抑制了压敏粘合剂层中多奈哌齐相关物质的生产的含多奈哌齐的贴剂。解决方案：包含至少一种或多种选自抗坏血酸，金属盐或其酯，异抗坏血酸或其金属盐，乙二胺四乙酸或其金属盐，半胱氨酸，乙酰半胱氨酸，2- 巯基苯并咪唑，3（2） - 叔丁基-4-羟基苯甲醚，2,6-二叔丁基-4-甲基苯酚，四[3-（3'，5'-二叔丁基-4'-羟基苯基）丙酸]季戊四醇，3-巯基-1,2-丙二醇，生育酚乙酸酯，芦丁，槲皮素，氢醌，羟基甲烷亚磺酸的金属盐，偏亚硫酸氢盐，金属亚硫酸盐和金属硫代硫酸盐掺入含多奈哌齐的压力设置在支撑体的至少一侧的敏感性粘合剂层。版权所有（C）2013，JPO＆INPIT

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