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1. 发明授权

US07736337B2 Sealing catheter hub attachment 有权
标题翻译：密封导管座附件
公开(公告)号：US07736337B2
公开(公告)日：2010-06-15
申请号：US11276155
申请日：2006-02-16
申请人： Nhut M Diep , David J Goral , Alan D King , Thomas T Koehler
发明人： Nhut M Diep , David J Goral , Alan D King , Thomas T Koehler
IPC分类号： A61M5/00
CPC分类号： A61M39/06 , A61M25/0097 , A61M25/0612 , A61M39/0606 , A61M2039/062 , A61M2039/0633 , A61M2039/0646 , A61M2039/0686
摘要： A generally rigid molded plastic catheter hub attachment (16, 52, 74) includes one or more co-molded elastomeric gaskets (22, 58).
摘要翻译：通常刚性的模制塑料导管毂连接件（16,52,74）包括一个或多个共模塑弹性垫片（22,58）。

2. 发明授权

US07658725B2 Enclosed needle device with duckbill release mechanism 有权
标题翻译：带鸭嘴释放机构的封闭针装置
公开(公告)号：US07658725B2
公开(公告)日：2010-02-09
申请号：US11276152
申请日：2006-02-16
申请人： Dennis M Bialecki , Nhut M Diep , Alan D King , Thomas T Koehler
发明人： Dennis M Bialecki , Nhut M Diep , Alan D King , Thomas T Koehler
IPC分类号： A61M5/178
CPC分类号： A61M25/0631 , A61M5/3271 , A61M25/0606 , A61M2005/3247
摘要： An enclosed needle catheter insertion device (10) includes a catheter (12) and a needle insertion device (14) which are held together by cooperating arms (52, 53) with one or more detents (56) cooperating with a radially projecting surface (26) of the catheter hub (16). Insertion device (14) includes a guard housing (30) to enclose a needle (34) in a shielded position and a support housing (32) supporting the needle (34) for movement between a ready position, with the tip (36) of the needle (34) exposed, to the shielded position. Cooperating lock elements (47, 78) are provided for the housings (30, 32) which are positioned to define a lock actuation stage between the ready and shielded positions, whereat the needle is still within a passageway (54) defined by the cooperating arms (52, 53).
摘要翻译：封闭的针导管插入装置（10）包括导管（12）和针插入装置（14），它们通过配合的臂（52,53）与一个或多个与径向突出的表面配合的棘爪（56） 26）。插入装置（14）包括用于将针（34）封闭在屏蔽位置的保护壳体（30）和支撑针（34）的支撑壳体（32），用于在就绪位置与准备位置之间移动，该就绪位置与尖端针（34）暴露于屏蔽位置。为壳体（30,32）设置合作的锁定元件（47,78），所述壳体（30,32）被定位成在准备位置和屏蔽位置之间限定锁定致动台，其中针仍在由协作臂限定的通道（54）内（52,53）。

3. 发明授权

US07632243B2 Duckbill catheter release mechanism 有权
标题翻译：鸭嘴导管释放机制
公开(公告)号：US07632243B2
公开(公告)日：2009-12-15
申请号：US11161554
申请日：2005-08-08
申请人： Dennis M Bialecki , David J Goral , Alan D King , Sean J Albert , Thomas K Sutton
发明人： Dennis M Bialecki , David J Goral , Alan D King , Sean J Albert , Thomas K Sutton
IPC分类号： A61M5/00
CPC分类号： A61M25/0618 , A61M5/3273 , A61M2005/325
摘要： A needle guard includes a clip with a canting wall to grip the needle shaft and a distal wall to block the tip thereof, wherein the canting and distal walls may be interconnected by an angled strut, a spring member, such as a leaf spring, may have a portion extending past an edge of the strut to bias the clip to grip the needle shaft, and the distal wall may be or include a stylus and have an L-shape to define a lip to help block the needle tip. The clip may have a depending heel to help pivot the clip about a ledge to grip the needle shaft. A needle support may be provided to limit flexure of the needle which might otherwise allow the needle to come loose from the clip. Arrangements for limiting rotation of the needle hub and needle guard housing are provided, as is a protective shroud to reduce the risk of inadvertent activation of the needle guard. Further, the needle guard may be used with a catheter assembly. Also provided is an improved duckbill release mechanism.
摘要翻译：针护罩包括具有倾斜壁以夹持针轴的夹子和用于阻挡其尖端的远侧壁，其中倾斜和远侧壁可以通过成角度的支柱，诸如板簧的弹簧构件相互连接，具有延伸穿过支柱的边缘的部分以偏置夹子以夹持针轴，并且远侧壁可以是或包括触针并且具有L形以限定唇缘以帮助阻止针尖。夹子可以具有悬垂的鞋跟，以帮助夹子围绕凸缘枢转以夹紧针轴。可以提供针支撑件来限制针的弯曲，否则可能会使针从夹子中松脱。提供了用于限制针座和针保护壳的旋转的布置，保护罩也是如此，以减少针保护装置的无意的激活的风险。此外，针护罩可以与导管组件一起使用。还提供了改进的鸭嘴释放机构。

4. 发明授权

US10494626B2 Dynamic mixing and electroporation chamber and system 有权
公开(公告)号：US10494626B2
公开(公告)日：2019-12-03
申请号：US13261509
申请日：2011-05-11
申请人： Alan D King , Stephen B Deitz , Donald J Rodis, Jr. , Derin C Walters , Robert J Walters
发明人： Alan D King , Richard E Walters , Stephen B Deitz , Donald J Rodis, Jr. , Derin C Walters
IPC分类号： C12N13/00 , C12M1/42
CPC分类号： C12N13/00 , C12M35/02
摘要： An electroporation apparatus and its novel chamber with inlet ports for mixing cells and exogenous material. The inlet ports are oriented in nonparallel to each other immediately adjacent at the same top corner of the first wall of the chamber. The mixing chamber comprises successive wall sections, two curved walls at its bottom; the first curved corner is on the same side of the chamber where the liquids enter the chamber, and directs the liquids to the second curved corner at the opposing side of the chamber which in turn further redirects the mixing to the first curved corner. The direction of the liquid flow mixture change direction at least twice into the mixing chamber.

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