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    • 1. 发明授权
    • Method for assaying L-phenylalanine and L-phenylalanine sensor
    • 测定L-苯丙氨酸和L-苯丙氨酸传感器的方法
    • US06468416B1
    • 2002-10-22
    • US09743571
    • 2001-01-12
    • Kenji NakamuraToru YokoyamaNaoki Shinozuka
    • Kenji NakamuraToru YokoyamaNaoki Shinozuka
    • G01N27327
    • C12Q1/32C12Q1/005
    • An L-phenylalanine sensor wherein all of the reagents required in determining L-phenylalanine are integrated together, thereby enabling quick and convenient quantification without resort to any special equipment, devices or techniques. This sensor is fabricated by integrating L-phenylalanine dehydrogenase, oxidized nicotinamide adenine dinucleotide (NAD+) or oxidized nicotinamide adenine dinucleotide phosphate (NADP+) as a coenzyme and an electron mediator, which are employed as reagents, with an electrode system comprising at least a working electrode and a counter electrode. Also, a method of determining L-phenylalanine which comprises adding a sample containing L-phenylalanine to the above-described sensor and electrochemically quantitating L-phenylalanine is provided.
    • L-苯丙氨酸传感器,其中将L-苯丙氨酸测定所需的全部试剂整合在一起,从而能够快速方便地进行定量,而无需使用任何特殊的设备,装置或技术。 该传感器通过将用作试剂的L-苯丙氨酸脱氢酶,氧化烟酰胺腺嘌呤二核苷酸(NAD +)或氧化烟酰胺腺嘌呤二核苷酸磷酸酯(NADP +)和电子介体整合在一起而制成,电极系统至少包括一个工作 电极和对电极。 此外,提供了一种测定L-苯丙氨酸的方法,其包括向上述传感器中加入含有L-苯丙氨酸的样品并进行电化学定量的L-苯丙氨酸。
    • 2. 发明授权
    • Method of determining substrate, and biosensor
    • 确定底物和生物传感器的方法
    • US06720164B1
    • 2004-04-13
    • US09914292
    • 2001-08-27
    • Naoki ShinozukaToru YokoyamaKenji Nakamura
    • Naoki ShinozukaToru YokoyamaKenji Nakamura
    • C12Q132
    • C12Q1/005
    • A method of quantifying a substrate, by which the substrate contained in various samples can be conveniently and quickly quantified without resort to any troublesome pretreatments, and a biosensor. More particularly speaking, a method of quantifying a substrate in a sample by using an electrode system made of electrically conductive materials and a reaction reagent comprising at least a dehydrogenase, a coenzyme an electron mediator and a tetrazolium salt, which comprises performing an enzyme reaction and a redox reaction between the reaction reagent and the substrate in the sample, and detecting a formazan formed as the final reaction product by using the electrode system and a if biosensor with the use of the same are provided.
    • 定量底物的方法,通过该方法可以方便快速地定量各种样品中所含的底物,而不需要任何麻烦的预处理和生物传感器。 更具体地说,通过使用由导电材料制成的电极系统和至少包含脱氢酶,辅酶,电子介体和四唑鎓盐的反应试剂来定量样品中的底物的方法,其包括进行酶反应和 提供样品中反应试剂和底物之间的氧化还原反应,并且通过使用电极系统和如果使用其的生物传感器检测形成为最终反应产物的甲。。
    • 8. 发明授权
    • Eye measurement apparatus
    • 眼睛测量仪器
    • US09173556B2
    • 2015-11-03
    • US13334944
    • 2011-12-22
    • Kenji NakamuraMitsuhiro Gono
    • Kenji NakamuraMitsuhiro Gono
    • A61B3/10A61B3/00A61B3/032A61B3/036
    • A61B3/0008A61B3/032A61B3/036
    • An eye measurement apparatus includes: a subjective measurement optical system configured to subjectively measure an examinee's eye, the subjective measurement optical system including: a chart to be presented to the examinee's eye; and a glare light source for irradiating the examinee's eye with a glare light; and a control part configured to determine presence or absence of opacity in a light transmitting part of the examinee's eye and, when the presence of opacity is determined, to allow display of necessity for a glare test which is a subjective measurement to be performed in a state that the examinee's eye is irradiated with the glare light.
    • 眼睛测量装置包括:主观测量光学系统,被配置为主观地测量受检者的眼睛,所述主观测量光学系统包括:被呈现给受检者的眼睛的图; 以及用眩光照射被检眼的眩光光源; 以及控制部,其被配置为确定被检眼的光透射部分中是否存在不透明度,并且当确定不透明度的存在时,允许显示作为主观测量的眩光测试的必要性,所述眩光测试是在 说明受试者的眼睛被眩光照射。