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1. 发明专利

DE69212629D1 未知
公开(公告)号：DE69212629D1
公开(公告)日：1996-09-12
申请号：DE69212629
申请日：1992-01-07
申请人： NIPPON KOKAN KK
发明人： YAMAZAKI SHIGEKI , NAKAGAWA HIDEYUKI
IPC分类号： G21G1/10 , G21G4/08
摘要： A method of synthesizing N-ammonia in a target in which a target water and hydrogen are sent into a synthesizing device under a pressure of 0.1-5 kg/cm , and while circulating the target water, N-ammonia is generated by projecting a proton beam on it. A method for synthesizing N-ammonia in a target in which the target water including N-ammonia generated by the foregoing method, is contacted with an Na cation exchange resin, and N-ammonia is caught on the cation exchange resin, and then, the caught N-ammonia is dissolved in a physiological salt solution by contacting the positive ion exchange resin with the physiological salt solution. A method for synthesizing a tag compound in which, each liquid of the target water and the physiological salt solution, etc., is sucked by a predetermined quantity from each liquid tank into a syringe, the piston of the syringe is pressed down to inject the liquid into a synthesizing vessel in a state that the pipe connecting the syringe and the synthesizing vessel is closed, and the displacement of the piston of the syringe is measured. If the displacement exceeds a predetermined value, it is judged that the liquid quantity sucked into the syringe is insufficient. If it does not exceed, the liquid is injected into the vessel, opening the pipe. It is possible to synthesize in a short time N-ammonia of a high quality, which is suitable to PET (Positron Emission Tomography) system of a kind of tomography utilized for diagnosing sicknesses, etc.

2. 发明专利

DE69132724D1 未知
公开(公告)号：DE69132724D1
公开(公告)日：2001-10-18
申请号：DE69132724
申请日：1991-06-17
申请人： NIPPON KOKAN KK
发明人： FUJISAWA YOSHIKI , YAMAZAKI SHIGEKI , NAKAGAWA HIDEYUKI , TAKAHASHI NAOKO
IPC分类号： C07B59/00 , C07C19/07
摘要： In a process for the synthesis of C-labeled methyl iodide which comprises producing CO2 by the irradiation of proton beam, supplying CO2 gas to a collector of CO2 gas, bubbling CO2 gas into a reducing agent solution to reduce CO2, removing the reducing agent solution by the evaporation, synthesizing CH3I from the reduced product of CO2, and recovering CH3I by distillation, the termination point of the CO2 gas supply, the termination point of the bubbling, the termination of the evaporation of the reducing agent solution or the termination point of the distillation of CH3I is decided by a radiation sensor provided in the vicinity of the reaction vessel or the transfer tube connecting the target box wherein CO2 gas is generated or a temperature sensor provide in the exhaust tube of the reaction vessel. The synthesizing time is shortened, and the yield of CH3I is improved by improving the utilization of CO2 gas and the recovery of CH3I of which the half-life is very short.

3. 发明专利

CA2085590A1 SYNTHESIS OF LABELED COMPOUND 未知
公开(公告)号：CA2085590A1
公开(公告)日：1992-10-18
申请号：CA2085590
申请日：1992-01-07
申请人： NIPPON KOKAN KK
发明人： YAMAZAKI SHIGEKI , NAKAGAWA HIDEYUKI
IPC分类号： G21G1/10 , G21G4/08
摘要： A process for the synthesis of 13N-ammonia in target which comprises charging target water and hydrogen into a synthesis apparatus to make a pressurized condition at 0.1-5 kg/cm2 and irradiating proton beam to the target water which is circulated to produce 13N-ammonia, a process for the synthesis of 13N-ammonia in target which comprises bringing the target water containing 13N-ammonia thus produced into contact with a Na type cation-exchange resin to collect 13N-ammonia by the cation-exchange, and then bringing the cation-exchange resin into contact with a saline solution to elute the collected 13N-ammonia into the saline solution, and a process for the synthesis of a labeled compound, at the time of sucking a prescribed amount of the liquid of the target water, saline solution or the like into a syringe and injecting the liquid from the syringe into the above vessel, comprising depressing the piston of the syringe in the state that the pipe connecting the syringe and the vessel has been once closed to detect the displacement of the piston, and in the case that the displacement exceeds a prescribed value, judging that the sucked amount of the liquid into the syringe is short, on the other hand in the case that the displacement is not more than the prescribed value, opening said pipe to inject the liquid into the vessel. The method of the invention can synthesize high purity 13N-ammonia in a short time which is suitable for the PET (Positron Emission Tomography) system which is a kind of tomography utilized for the dragnosis of disease, etc.

4. 发明专利

JPH1134729A CONTAINER CONVEYING CARRIAGE, AND CONTROL THEREFOR 失效
公开(公告)号：JPH1134729A
公开(公告)日：1999-02-09
申请号：JP19251797
申请日：1997-07-17
申请人： NIPPON KOKAN KK
发明人： NAKAGAWA HIDEYUKI , OSHIDA EIJI , MURANO KENICHI , NOMURA SADAO
IPC分类号： B60P7/13
摘要： PROBLEM TO BE SOLVED: To provide a conveying carriage capable of fixing a container to the carriage without requiring high positioning accuracy for the carriage and a crane, capable of utilizing conveying capacity to the utmost, and capable of preventing any influence to moving performance of the carriage, and provide a controlling method therefor. SOLUTION: This container conveying carriage has a platform to mount a container, and container guides to fit to plural kinds of container sizes. A container guide in the longitudinal direction of a container 1 is provided with a turning pawl 4 turnably attached to the platform, a torque applying means applying torque normally to the direction to project the pawl 4 from the platform, and a turning angle sensor to detect a turning angle of the pawl 4. Recesses for fixing the container are formed in the pawl 4 at plural positions with different distances from its turning center.

5. 发明专利

JP2853071B2 失效
公开(公告)号：JP2853071B2
公开(公告)日：1999-02-03
申请号：JP3208592
申请日：1992-02-19
申请人： NIPPON KOKAN KK
发明人： MIZUNO KENICHIRO , YAMAZAKI SHIGEKI , NAKAGAWA HIDEYUKI
IPC分类号： G01T1/161 , A61M5/168

6. 发明专利

JPH07119836B2 失效
公开(公告)号：JPH07119836B2
公开(公告)日：1995-12-20
申请号：JP8536791
申请日：1991-04-17
申请人： NIPPON KOKAN KK
发明人： YAMAZAKI SHIGEKI , NAKAGAWA HIDEYUKI
IPC分类号： B01J39/04 , C01C1/10 , G21G1/10 , G21G4/08

7. 发明专利

JPH0449254A METHOD FOR SYNTHESIZING METHYL IODIDE LABELED WITH 11C AND APPARATUS FOR SYNTHESIZING THE SAME 失效
公开(公告)号：JPH0449254A
公开(公告)日：1992-02-18
申请号：JP15927690
申请日：1990-06-18
申请人： NIPPON KOKAN KK
发明人： FUJISAWA YOSHIKI , YAMAZAKI SHIGEKI , NAKAGAWA HIDEYUKI , TAKAHASHI NAOKO
IPC分类号： G21G1/00 , C07B59/00 , C07C17/00 , C07C17/10 , C07C19/07
摘要： PURPOSE:To improve utilization efficiency of a raw material gaseous carbon dioxide labeled with C and shorten synthesis time of the objective compound by sensing radiation and judging the time of completing the feed of the aforementioned raw material to a reaction vessel with a change in the radiation in synthesizing the subject compound from the above-mentioned raw material. CONSTITUTION: CH3I useful as a labeling compound for a position emission tomography (PET) system used in a positron tomographic testing method is synthesized by a step for producing CO2 gas labeled with C in a target box 4, a step for feeding the CO2 gas produced in the above-mentioned step to a reaction vessel 14 and a step for synthesizing the CH3I labeled with the C from the CO2 gas in the aforementioned reaction vessel 14. In the process, radiation in a step 7 for feeding the aforementioned CO2 gas is sensed with a radiation sensor 22 to judge the time of completing the feed of the CO2 gas with a change (b) in output thereof. Thereby, utilization efficiency of the CO2 gas is enhanced and the synthesis time of the CH3I is simultaneously shortened.

8. 发明专利

JP2000159099A TRACK-EQUIPPED DOLLY 失效
公开(公告)号：JP2000159099A
公开(公告)日：2000-06-13
申请号：JP33769298
申请日：1998-11-27
申请人： NIPPON KOKAN KK
发明人： NAKAGAWA HIDEYUKI , SUZUKI HIROSHI , ISHIKAWA YOJI , SHODA KENSHO , OSHIDA EIJI , YOSHINAGA YOICHI , USAMI KAZUHIRO , KAWAMURA SHIGEO
IPC分类号： B61B13/00 , B65G1/00 , B65G35/00
摘要： PROBLEM TO BE SOLVED: To shorten a track-equipped dolly even if wheels for running are provided in front of and behind the loading space about in the dolly advancing direction in order to lessen the height of the dolly. SOLUTION: A track-equipped dolly is furnished with a loading space 20, a pair of running means 22A and 22B installed capable of revolving consolidatedly within a plane relative to the loading space 20 in positions in front of and behind the loading space about in the dolly advancing direction, and a controller 39. One of the running means 22A is furnished with a left and a right driving wheel 24 coupled together through a differential gear 27 and rolling on rails 21A and 21B and a driving mechanism 25 for driving the driving wheel 24. The other running means 22B is furnished with a left and a right follower wheel indepent of each other and rolling on the rails 21A and 21B and encodes mounted on the respective follwer wheels for generating pulses corresponding to the running distance of the dolly. The controller 39 controls the running of the dolly on the basis of the pulse signals given from the encoders.

9. 发明专利

JPH0634615A REFINERY FOR LABELLED COMPOUND AND THE LIKE 失效
公开(公告)号：JPH0634615A
公开(公告)日：1994-02-10
申请号：JP19076492
申请日：1992-07-17
申请人： NIPPON KOKAN KK
发明人： YAMAZAKI SHIGEKI , MIZUNO KENICHIRO , NAKAGAWA HIDEYUKI
IPC分类号： A61K49/00 , A61K51/00 , B01D15/08 , G01N30/24 , G01N30/80 , G21G4/08 , A61K49/02
摘要： PURPOSE:To provide a refinery for labelled compound etc., with which synthesized reaction liquid is, as a whole amount or almost that amount, supplied to the column of a liquid chromatography for refinery without the care about mingling of air bubble and effect of variation of liquid amount, while free of exposure problem. CONSTITUTION:A refinery far labelled compound etc., is provided with an intermediate vessel 2 which receives the mixture liquid of compound containing small quantity of impurities or synthesized reaction liquid of labelled compound or other small quantity of compound, a sample receiver part 7 which receives the synthesized reaction liquid taken out of the intermediate vessel 2 placed on the way of refinery line, a syringe 5 which feeds the synthesized reaction liquid from the intermediate vessel 2 to the sample receiver part 7, a column 11 of a liquid chromatography which develops and separates the synthesized reaction liquid, a mechanism 10 which feeds the developed solvent of the column 11, and a valve 3 which switches the connection of the sample receiver part 7, receiving the synthesized reaction liquid from the intermediate vessel 2 or supplying the column 11 with the liquid far liquid chromatography. A liquid level detection sensor 6 is provided at the bottom of the intermediate vessel 2, and a liquid drain pipe is connected to the bottom of intermediate vessel 2.

10. 发明专利

JPH04318499A SYNTHESIS METHOD FOR LABELED COMPOUND 失效
公开(公告)号：JPH04318499A
公开(公告)日：1992-11-10
申请号：JP8536891
申请日：1991-04-17
申请人： NIPPON KOKAN KK
发明人： YAMAZAKI SHIGEKI , NAKAGAWA HIDEYUKI
IPC分类号： G21G4/08 , G21H5/02
摘要： PURPOSE:To prevent a trouble in a solution injection device and shorten an operating time by adding a sensor valve to detect the displacement of a cylinder, and confirming the filling up state within the cylinder. CONSTITUTION:When a device is operated, a piston rod 51 is raised from the position of a sensor 54 by a driver 52, and liquids within vessels 20, 23 are sucked up into cylinders 21, 24 through three way valves 22, 25. The rod 51 stops when its lower end is detected by the upper detecting sensor 53. Next, three way valves 15, 16 are switched, a valve 56 is closed, the piston rod 51 is pushed down by the driver 52, it is judged that a sucked quantity is insufficient when that lower end is detected by a sensor 55, and the device is stopped and inspected. On the other hand, when the lower end is not detected by the sensor 55, the valve 56 is opened, the liquid is put into a cation exchange resin column 17. When the lower end of the piston rod 51 is detected by the sensor 54, the driver 52 is stopped, the putting in of the liquid is ended.

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