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    • 2. 发明专利
    • DE602005020157D1
    • 2010-05-06
    • DE602005020157
    • 2005-07-21
    • NIKKISO CO LTD
    • TARUMI MASATOSHIMORI YOSHIHIROTOYODA MASAHIROMURAKAMI TOMOYA
    • A61M1/14
    • A blood purification device allows confirming whether a specific peak is provided by a means, such as a ultrafiltration pump, to concentrate the blood or not and also allows measuring certainly and accurately a blood re-circulation with reduction of parameters which can provide a ratio of re-circulating blood. The blood purification device including blood circuit route 1 composed of arterial blood circuit route 1a and venous blood circuit route 1b, blood pump 3, dialyzer 2, water removal pump 8 which can provide the specific peak in the variation of blood concentration by removing water rapidly in a short period of time, and detecting means detecting said specific peak, can measure the blood re-circulation based on the specific peak detected by the detecting means. The re-circulating blood flowing is the blood which was introduced again to arterial blood circuit route 1a after it had been returned to a patient from venous blood circuit route 1b. The detecting means includes first detecting means 5a installed in arterial blood circuit route 1a and second detecting means 5b installed in venous blood circuit route 1b.
    • 6. 发明公开
    • EXTRACORPOREAL CIRCULATION DEVICE AND METHOD FOR ISOLATION TEMPERATURE CONTROL METHOD
    • EXTRAKORPORALE KREISLAUFVORRICHTUNG SOWIE VERFAHREN ZUR KONTROLLE DER ISOLATIONSTEMPERATUR
    • EP1132101A4
    • 2005-01-12
    • EP99972552
    • 1999-11-18
    • NIKKISO CO LTDOHTA TOMIO
    • OHTA TOMIOMIYATAKE TETSUYAKINOSHITA YOSHIHIKOMURAKAMI TOMOYA
    • A61M1/34A61M1/36
    • A61M1/3455A61M1/3441A61M1/3458A61M1/369A61M2230/207
    • An extracorporeal circulation device used for an isolation temperature control method to maintain an object at a preset temperature, comprising (A) a replenisher liquid supply unit which meters a temperature-controlled replenisher liquid for injecting into a blood vessel, (B) a blood concentrating unit which meters the replenisher liquid-diluted blood for guiding from the blood vessel and which concentrates the guided diluted blood, and (C) a blood supply unit which meters the concentrated blood for injecting into the blood vessel while a blood temperature is controlled, wherein the blood concentrating unit has a diluted blood temperature sensor for measuring a guided diluted blood temperature, and the replenisher liquid supply unit has a means for controlling a supplying replenisher liquid temperature based on the difference between a measured diluted blood temperature and a preset temperature of the object.
    • 包括:用于选择性温度控制方法的体外循环装置,其中物体的温度保持在预定温度, (A)液体替换供给单元,其定量地将已经调节了温度的液体置换供给到血管中; (B)血液浓度单元,其定量地从血管中取出由所述液体替换物稀释的血液,并浓缩所述抽出的稀释血液; 和(C)血液供给单元,其对已经浓缩并定量地将浓缩血液供给到血管中的血液的温度进行控制,所述血液浓度单元包括测量所述取出的稀释血液的温度的稀释型血液温度传感器, 并且所述流体置换供给单元包括基于所测量的稀释血液温度和所述物体的预定温度之间的不同程度来控制要供应的所述流体置换的温度的装置。
    • 7. 发明公开
    • BLOOD PURIFIER
    • 血液净化器
    • EP3042672A4
    • 2017-04-12
    • EP14840625
    • 2014-09-01
    • NIKKISO CO LTD
    • MURAKAMI TOMOYAAKITA KUNIHIKOTOYODA MASAHIRO
    • A61M1/14A61M1/16G01N33/483G06F19/00
    • A61M1/1603A61M1/1609A61M1/1613A61M2205/3306G06F19/3481
    • Provided is a blood purification apparatus which can continue to accurately monitor a blood purification treatment state even if treatment conditions are changed during blood purification treatment. The blood purification apparatus can perform real-time monitoring on the blood purification treatment state, based on a concentration change in a discharge solution which is obtained by an arithmetic device (12). The blood purification apparatus includes a treatment condition change device (13) that sets or changes treatment conditions as requested, and that causes a discharge solution concentration sensor (5) to previously detect concentration of the discharge solution under the respective treatment conditions, and a storage device (14) that stores the concentration of the discharge solution under the respective treatment conditions which is detected by the discharge solution concentration sensor (5) in the treatment condition change device (13), as a first predetermined value corresponding to the respective treatment conditions. When the treatment conditions are changed during blood purification treatment, the arithmetic device (12) obtains the concentration change in the discharge solution, based on the first predetermined value corresponding to the changed treatment conditions among the first predetermined values stored in the storage device (14).
    • 8. 发明公开
    • BLOOD PURIFICATION DEVICE
    • EP2514447A4
    • 2014-12-31
    • EP10837602
    • 2010-12-14
    • NIKKISO CO LTD
    • AKITA KUNIHIKOMURAKAMI TOMOYAHIRANO TAKAYUKITAKAKUWA YASUSHI
    • A61M1/14A61M1/16A61M1/36G01N21/05G01N21/27G01N21/59
    • A61M1/367A61M1/1692A61M2205/3306G01N21/05G01N21/274G01N21/59G01N2201/062G01N2201/0621
    • An object of the present invention is to provide a blood purification apparatus, which can minimize the detecting error of liquid concentration caused by temperature variation and thus improve the accuracy of detection of liquid with a concentration detecting means. According to the present invention there is provided a blood purification apparatus comprising a blood purification instrument for extracorporeally circulating blood of a patient and a concentration detecting means for detecting a concentration of liquid flowing during blood purification characterized in that the concentration detecting means comprises a light emitting means for irradiating light onto said liquid, a light receiving means for receiving light from the light emitting means transmitted through said liquid, a reference light receiving means for receiving reference light branched from the light emitting means without being transmitted through said liquid, and a detecting means for detecting the light intensity respectively of the transmitted light received by the light receiving means and the reference light received by the reference light receiving means, and that the blood purification apparatus further comprises an error absorbing means for detecting the concentration of the liquid based on the received light intensity of the transmitted light received by the light receiving means and detected by the detecting means and for absorbing a detected error of the concentration detecting means based on the received light intensity of the reference light received by the reference light receiving means.