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    • 1. 发明申请
    • SELF-REPLICATING MATERIALS
    • 自我更换材料
    • WO2008076414A2
    • 2008-06-26
    • PCT/US2007/025749
    • 2007-12-17
    • NEW YORK UNIVERSITYSEEMAN, NadrianCHAIKIN, Paul MichaelPINE, DavidGRIER, David G.
    • CHAIKIN, Paul MichaelPINE, DavidGRIER, David G.
    • C12Q1/68
    • C12Q1/682B82Y5/00B82Y20/00C12N15/10C12N15/1031C12N15/1068C12Q2563/155C12Q2565/113
    • The invention provides micron and sub-micron scale particles designed to recognize and selectively interact with each other by exploiting the recognition and specificity enabled by DNA-sequence-encoded coatings. Such materials possess sufficient information coded in their chemical and physical interactions to self assemble and self replicate. The invention further provides methods of using such materials to create self replicating and organizing materials. Replicated copies are permanently linked and then thermally detached, freeing them to act as templates for further growth. This new class of condensed matter systems, provides means to design and control the structure and function of materials and machines from the microscopic to life-size. In another aspect of the invention, depletion type forces and depletion zones can be utilized in the implementation of the self assembly and self replication of materials, including without limitation colloidal particles. The invention further provides novel means of synthesis and materials built by such synthesis, which may be used in a variety of applications, including microelectronics.
    • 本发明提供通过利用由DNA序列编码的涂层实现的识别和特异性来设计用于识别和选择性相互作用的微米级和亚微米级粒子。 这样的材料具有足够的信息,以其化学和物理相互作用编码,以自组装和自我复制。 本发明还提供了使用这种材料来创建自我复制和组织材料的方法。 复制副本永久链接,然后热分离,释放它们作为进一步增长的模板。 这种新型凝结物系统,提供了从微观到真实尺寸的材料和机器的结构和功能的设计和控制的手段。 在本发明的另一方面,耗尽型力和耗尽区可以用于实现材料的自组装和自我复制,包括但不限于胶体颗粒。 本发明还提供了新的合成方法和通过这种合成制备的材料,其可以用于包括微电子学在内的各种应用中。