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1. 发明申请

WO2009034165A1 WOLFBERRIES AND SKIN INFLAMMATION 审中-公开
标题翻译：玻璃和皮肤炎症
公开(公告)号：WO2009034165A1
公开(公告)日：2009-03-19
申请号：PCT/EP2008/062132
申请日：2008-09-12
申请人： NESTEC S.A. , L'OREAL , VIDAL, Karine , BLUM-SPERISEN, Stéphanie , PHILIPPE, David , BALLEVRE, Olivier , BUCHELI, Peter , WANG, Junkuan
发明人： VIDAL, Karine , BLUM-SPERISEN, Stéphanie , PHILIPPE, David , BALLEVRE, Olivier , BUCHELI, Peter , WANG, Junkuan
IPC分类号： A61K36/815 , A61P29/00
CPC分类号： A61K36/815
摘要： The present invention relates in general to the field of inflammation. In particular the present invention relates to the use of natural compounds for the preparation of a product to treat or prevent inflammation. For example an extract of wolfberry was shown to have anti-inflammatory properties. One embodiment of the present invention relates to the use of a primary composition comprising wolfberries or a part thereof for the preparation of a product to treat or prevent inflammation.
摘要翻译：本发明一般涉及炎症领域。特别地，本发明涉及天然化合物在制备治疗或预防炎症的产品中的用途。例如，枸杞提取物显示具有抗炎特性。本发明的一个实施方案涉及包含枸杞或其一部分的主要组合物在制备用于治疗或预防炎症的产品中的用途。

2. 发明申请

WO2009034162A1 WOLFBERRIES AND INFLAMMATION 审中-公开
标题翻译：玻璃杯和烧伤
公开(公告)号：WO2009034162A1
公开(公告)日：2009-03-19
申请号：PCT/EP2008/062122
申请日：2008-09-12
申请人： NESTEC S.A. , VIDAL, Karine , BLUM-SPERISEN, Stéphanie , PHILIPPE, David , BALLEVRE, Olivier , BUCHELI, Peter , WANG, Junkuan
发明人： VIDAL, Karine , BLUM-SPERISEN, Stéphanie , PHILIPPE, David , BALLEVRE, Olivier , BUCHELI, Peter , WANG, Junkuan
IPC分类号： A61K36/815 , A61P29/00
CPC分类号： A61K36/815
摘要： The present invention relates in general to the field of inflammation. In particular the present invention relates to the use of natural compounds for the preparation of a product to treat or prevent inflammation. For example an extract of wolfberry was shown to have anti-inflammatory properties. One embodiment of the present invention relates to the use of a primary composition comprising wolfberries or a part thereof for the preparation of a product to treat or prevent inflammation.
摘要翻译：本发明一般涉及炎症领域。特别地，本发明涉及天然化合物在制备治疗或预防炎症的产品中的用途。例如，枸杞提取物显示具有抗炎特性。本发明的一个实施方案涉及包含枸杞或其一部分的主要组合物在制备用于治疗或预防炎症的产品中的用途。

3. 发明申请

WO2012052463A1 CYSTEINE AND FOOD INTAKE 审中-公开
标题翻译： CYSTEINE和食物摄入
公开(公告)号：WO2012052463A1
公开(公告)日：2012-04-26
申请号：PCT/EP2011/068231
申请日：2011-10-19
申请人： NESTEC S.A. , INRA , BREUILLE, Denis , PAPET, Isabelle , VIDAL, Karine
发明人： BREUILLE, Denis , PAPET, Isabelle , VIDAL, Karine
IPC分类号： A61K31/198 , A61P1/14 , A61P3/04
CPC分类号： A61K31/198 , A23L33/175
摘要： The present invention relates to the field of nutrition; in particular to the prevention and/or treatment of malnutrition. One embodiment of the present invention relates to a nutritional composition enriched in cysteine for use in the treatment and/or prevention of malnutrition and disorders related thereto. Such a composition may in particular, but not exclusively, be useful for the elderly population.
摘要翻译：本发明涉及营养领域; 特别是预防和/或治疗营养不良。本发明的一个实施方案涉及富含半胱氨酸的营养组合物，用于治疗和/或预防与其相关的营养不良和紊乱。这样的组合物可能特别但不排他地对老年人有用。

4. 发明申请

WO2009135867A1 SIALIC ACID TO SUPPORT SALIVATION 审中-公开
标题翻译： SIALIC ACID以支持SALIVATION
公开(公告)号：WO2009135867A1
公开(公告)日：2009-11-12
申请号：PCT/EP2009/055461
申请日：2009-05-06
申请人： NESTEC S.A. , SPRENGER, Norbert , VIDAL, Karine , CHERBUT, Christine , JANN, Alfred
发明人： SPRENGER, Norbert , VIDAL, Karine , CHERBUT, Christine , JANN, Alfred
IPC分类号： A61K31/70 , A61P1/02
CPC分类号： A61K31/70 , A23L33/10 , A23V2002/00 , A23V2250/5438 , A23V2200/302
摘要： The present invention generally relates to the field of disorders related to an impaired salivation and compositions that can be used to treat or prevent such disorders. One embodiment of the present invention relates to a composition comprising sialic acid to treat and/or prevent disorders linked to an impaired salivation.
摘要翻译：本发明一般涉及与受损的唾液分泌相关的疾病领域和可用于治疗或预防这种疾病的组合物领域。本发明的一个实施方案涉及包含唾液酸以治疗和/或预防与唾液分泌受损有关的紊乱的组合物。

5. 发明申请

WO2010031744A1 WHEY AND THYMUS FUNCTION 审中-公开
标题翻译： WHEY和THYMUS功能
公开(公告)号：WO2010031744A1
公开(公告)日：2010-03-25
申请号：PCT/EP2009/061876
申请日：2009-09-14
申请人： NESTEC S.A. , VIDAL, Karine , DELPIERRE, Eric , LOI, Cécile , MOINARD, Christophe , CHARRUEAU, Christine , BREUILLE, Denis , CYNOBER, Luc
发明人： VIDAL, Karine , DELPIERRE, Eric , LOI, Cécile , MOINARD, Christophe , CHARRUEAU, Christine , BREUILLE, Denis , CYNOBER, Luc
IPC分类号： A61K38/01 , A61K35/20 , A61P37/02
CPC分类号： A61K35/20 , A61K35/745 , A61K35/747 , A61K36/064 , A61K38/018 , A61K2300/00
摘要： The present invention generally relates to the field of nutrition and health. In particular, the present invention provides a composition that can be used to maintain or improve thymus health. One embodiment of the present invention is the use of whey or at least one protein fraction thereof for the preparation of a composition to maintain or improve thymus function.
摘要翻译：本发明一般涉及营养与健康领域。特别地，本发明提供可用于维持或改善胸腺健康的组合物。本发明的一个实施方案是使用乳清或其至少一种蛋白质级分来制备组合物以维持或改善胸腺功能。

6. 发明申请

WO2009135858A1 SIALIC ACID TO SUPPORT THE IMMUNE SYSTEM IN THE ELDERLY 审中-公开
标题翻译：在酸奶中支持免疫系统
公开(公告)号：WO2009135858A1
公开(公告)日：2009-11-12
申请号：PCT/EP2009/055444
申请日：2009-05-06
申请人： NESTEC S.A. , SPRENGER, Norbert , VIDAL, Karine , CHERBUT, Christine
发明人： SPRENGER, Norbert , VIDAL, Karine , CHERBUT, Christine
IPC分类号： A23L1/30 , A61K31/7012 , A61K38/00 , A61P37/04 , A61P29/00 , A61P31/00
CPC分类号： A61K31/7012 , A23L33/10 , A23V2002/00 , A23V2250/5438 , A23V2200/302
摘要： The present invention generally relates to the field of the immune system, in particular to strengthening the immune system of the elderly. One embodiment of the present invention relates to the use of a food product enriched with sialic acid for the preparation of a composition to strengthen the immune system.
摘要翻译：本发明一般涉及免疫系统领域，特别是加强老年人的免疫系统。本发明的一个实施方案涉及富含唾液酸的食品用于制备组合物以增强免疫系统的用途。

7. 发明申请

WO2002081521A3 OSTEOPROTEGERIN IN MILK 审中-公开
公开(公告)号：WO2002081521A3
公开(公告)日：2002-10-17
申请号：PCT/EP2002/002912
申请日：2002-03-15
申请人： SOCIÉTÉ DES PRODUITS NESTLÉ , VIDAL, Karine , VAN DEN BROEK, Peter , OFFORD CAVIN, Elizabeth , DONNET-HUGUES, Anne
发明人： VIDAL, Karine , VAN DEN BROEK, Peter , OFFORD CAVIN, Elizabeth , DONNET-HUGUES, Anne
IPC分类号： C07K14/705
摘要： The present invention pertains to osteoprotegerin obtainable from milk sources, in particular human and bovine milk. The present invention also relates to the use thereof for preparing an ingestible preparation and/or a pharmaceutical composition, in particular to the use of such a preparation/composition for preventing or treating disorders associated with bone metabolism and immune function.

8. 发明申请

WO2002094296A1 LIPOTEICHOIC ACID FROM LACTIC ACID BACTERIA AND ITS USE TO MODULATE IMMUNE RESPONSES MEDIATED BY GRAM-NEGATIVE BACTERIA, POTENTIAL PATHOGENIC GRAM-POSITIVE BACTERIA 审中-公开
标题翻译：来自酸性细菌的LIPOTEICHOIC酸及其用于调节由GRAM-阴性细菌介导的免疫应答，潜在致病性GRAM-阳性细菌
公开(公告)号：WO2002094296A1
公开(公告)日：2002-11-28
申请号：PCT/EP2002/004436
申请日：2002-04-23
申请人： SOCIETE DES PRODUITS NESTLE S.A. , VIDAL, Karine , DONNET-HUGHES, Anne , GRANATO, Dominique-Anne , CORTHESY-THEULAZ, Irène
发明人： VIDAL, Karine , DONNET-HUGHES, Anne , GRANATO, Dominique-Anne , CORTHESY-THEULAZ, Irène
IPC分类号： A61K35/74
CPC分类号： A61K31/70 , A23L33/135 , A23V2002/00 , A61K8/72 , A61K8/99 , A61K9/0095 , A61K31/739 , A61Q11/00 , A61Q19/00 , C12P19/44 , A23V2250/206
摘要： The invention relates to a composition for modulating the immune responses induced by Gram negative bacteria, potential pathogenic Gram positive bacteria and/or their derivatives, comprising lipoteichoic acid from lactic acid bacteria as an active ingredient. It also relates to the use of a lipoteichoic acid from lactic acid bacteria as an active ingredient and/or lactic acid bacteria producing it and/or its supernatant of culture, in the manufacture of a medicament, an oral or topical product for cosmetic, dermatological or ophtalmological applications, a food or petfood composition for modulating bacterial colonisation, immune responses and decreasing the inflammatory processes associated with bacterially-mediated disease and infection in the gastrointestinal tract, bone, skin, eye, ear, lung and oral cavity. The invention also relates to lipoteichoic acid selected thereof.
摘要翻译：本发明涉及一种用于调节由革兰氏阴性细菌诱导的免疫应答组合物，其可能致病性革兰氏阳性细菌和/或其衍生物包含来自乳酸菌的脂磷壁酸作为活性成分。它还涉及在制备用于化妆品，皮肤病学的药物，口服或局部产品中使用来自乳酸菌的脂磷壁酸作为活性成分和/或产生其的乳酸菌和/或其培养上清液或眼科应用，用于调节细菌定植，免疫应答和减少与细菌介导的疾病和胃肠道，骨骼，皮肤，眼睛，耳朵，肺和口腔中的感染相关的炎症过程的食物或宠物食品组合物。本发明还涉及其选择的脂磷壁酸。

9. 发明申请

WO2013143839A1 EARLY BIOMARKERS OF AGE-RELATED LOW-GRADE INFLAMMATION 审中-公开
标题翻译：与年龄相关的低等级炎症的早期生物标志物
公开(公告)号：WO2013143839A1
公开(公告)日：2013-10-03
申请号：PCT/EP2013/054987
申请日：2013-03-12
申请人： NESTEC S.A. , INRA
发明人： BRAHMBHATT, Viral , BREUILLE, Denis , GUY, Philippe Alexandre , MONTOLIU ROURA, Ivan , PAPET, Isabelle , VIDAL, Karine
IPC分类号： G01N33/68
CPC分类号： G01N33/492 , G01N33/6893 , G01N2800/7042 , G01N2800/7095
摘要： The present invention relates to a method for predicting the risk of acquiring an age-related low-grade inflammation for a subject, said method comprising a) providing a biological sample from a subject, b) determining in said sample the level of at least one biomarker selected from the group consisting of a compound of molecular weight between 859-863 g/mol and which is an alkylacylphosphatidylcholine, a compound of molecular weight between 861-86 g/mol and which is a diacylphosphatidylcholine, a compound of molecular weight between 791-794 g/mol and which is an alkylacylphosphatidylcholine, a compound of molecular weight between 522-525 g/mol and which is a monoacylphosphatidylcholine, octadecanoylcarnitine (C18), and tryptophan, c) comparing the level of the at least one biomarker to a reference level, and d) determining whether said subject is likely to be at risk of acquiring an age-related low-grade inflammation, when the level of biomarker(s) deviate significantly from the respective reference level.
摘要翻译：本发明涉及一种用于预测获得受试者年龄相关的低度炎症的风险的方法，所述方法包括：a）从受试者提供生物样品，b）在所述样品中确定至少一种选自分子量在859-863g / mol之间的化合物，其为烷基酰基磷脂酰胆碱，分子量在861-86g / mol之间的化合物，其为二酰基磷脂酰胆碱，分子量为791的化合物 -794g / mol，其为烷基酰基磷脂酰胆碱，分子量为522-525g / mol的化合物，其为单酰基磷脂酰胆碱，十八烷酰基肉碱（C18）和色氨酸，c）将至少一种生物标志物的水平与参考水平，以及d）当生物标志物的水平显着偏离呼吸时，确定所述受试者是否可能处于获得年龄相关的低度炎症的风险中实际参考水平。

10. 发明公开

EP2200623A1 WOLFBERRIES AND INFLAMMATION 审中-公开
标题翻译：枸杞和炎症
公开(公告)号：EP2200623A1
公开(公告)日：2010-06-30
申请号：EP08804087.8
申请日：2008-09-12
申请人： Nestec S.A.
发明人： VIDAL, Karine , BLUM-SPERISEN, Stéphanie , PHILIPPE, David , BALLEVRE, Olivier , BUCHELI, Peter , WANG, Junkuan
IPC分类号： A61K36/815 , A61P29/00
CPC分类号： A61K36/815
摘要： The present invention relates in general to the field of inflammation. In particular the present invention relates to the use of natural compounds for the preparation of a product to treat or prevent inflammation. For example an extract of wolfberry was shown to have anti-inflammatory properties. One embodiment of the present invention relates to the use of a primary composition comprising wolfberries or a part thereof for the preparation of a product to treat or prevent inflammation.

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