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1. 发明申请

WO2010001247A2 METHODS AND SYSTEMS FOR DISCRIMINATING BANDS IN SCALOGRAMS 审中-公开
标题翻译：用于分类标准中银行的方法和系统
公开(公告)号：WO2010001247A2
公开(公告)日：2010-01-07
申请号：PCT/IB2009/006181
申请日：2009-06-29
申请人： NELLCOR PURITAN BENNETT IRELAND , WATSON, James, Nicholas , ADDISON, Paul, Stanley , CLIFTON, David
发明人： WATSON, James, Nicholas , ADDISON, Paul, Stanley , CLIFTON, David
CPC分类号： G06K9/00516 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/14551 , A61B5/7207 , A61B5/7225 , A61B5/7239 , A61B5/726
摘要： The present disclosure is directed towards embodiments of systems and methods for discriminating (e.g., masking out) scale bands that are determined to be not of interest from a scalogram derived from a continuous wavelet transform of a signal. Techniques for determining whether a scale band is not of interest include, for example, determining whether a scale band's amplitude is being modulated by one or more other bands in the scalogram. Another technique involves determining whether a scale band is located between two other bands and has energy less than that of its neighboring bands. Another technique involves determining whether a scale band is located at about half the scale of another, more dominant (i.e., higher energy) band.
摘要翻译：本公开涉及用于从由信号的连续小波变换导出的标尺来鉴别（例如，屏蔽）被确定为不感兴趣的标度带的系统和方法的实施例。用于确定缩放带是否不感兴趣的技术包括例如确定缩放带的幅度是否正在由缩放图中的一个或多个其他频带调制。另一种技术涉及确定尺度带是位于两个其他频带之间，并且具有小于其相邻频带的能量的能量。另一种技术涉及确定刻度带是否位于另一个（更高的能量）带的大约一半的尺度。

2. 发明申请

WO2010001242A1 SYSTEMS AND METHODS FOR RIDGE SELECTION IN SCALOGRAMS OF SIGNALS 审中-公开
标题翻译：用于信号标度选择的系统和方法
公开(公告)号：WO2010001242A1
公开(公告)日：2010-01-07
申请号：PCT/IB2009/006150
申请日：2009-06-29
申请人： NELLCOR PURITAN BENNETT IRELAND , WATSON, James, Nicholas , ADDISON, Paul, Stanley , CLIFTON, David
发明人： WATSON, James, Nicholas , ADDISON, Paul, Stanley , CLIFTON, David
IPC分类号： A61B5/00
CPC分类号： A61B5/0806 , A61B5/0816 , A61B5/14551 , A61B5/726 , G06K9/0053
摘要： According to embodiments, systems, devices, and methods for ridge selection in scalograms are disclosed. Ridges or ridge components are features within a scalogram which may be computed from a signal such as a physiological (e.g., photoplethysmographic) signal. Ridges may be identified from one or more scalograms of the signal. Parameters characterizing these ridges may be determined.. Based at least in part on these parameters, a ridge density distribution function is determined. A ridge is selected from analyzing this ridge density distribution function. In some embodiments, the selected ridge is used to determine a physiological parameter such as respiration rate.
摘要翻译：根据实施例，公开了用于缩放图中的脊选择的系统，装置和方法。脊或脊组件是可以从诸如生理（例如，光电体积描记号）信号的信号计算的标尺内的特征。可以从信号的一个或多个缩放图来识别脊。可以确定表征这些脊的参数。至少部分地基于这些参数，确定脊密度分布函数。从分析该脊密度分布函数中选择脊。在一些实施例中，所选择的脊用于确定诸如呼吸速率的生理参数。

3. 发明申请

WO2012131290A1 SYSTEMS AND METHODS FOR AUTONOMIC NERVOUS SYSTEM MONITORING 审中-公开
标题翻译：用于自动神经系统监测的系统和方法
公开(公告)号：WO2012131290A1
公开(公告)日：2012-10-04
申请号：PCT/GB2012/000269
申请日：2012-03-22
申请人： NELLCOR PURITAN BENNETT IRELAND , ADDISON, Paul, Stanley , WATSON, James, Nicholas
发明人： ADDISON, Paul, Stanley , WATSON, James, Nicholas
IPC分类号： A61B5/024
CPC分类号： A61B5/14551 , A61B5/0205 , A61B5/02405 , A61B5/02416 , A61B5/0816 , A61B5/091 , A61B5/4035 , A61B5/7257 , A61B5/726 , A61B2562/085
摘要： Methods and systems are disclosed for determining physiological information about a patient's autonomic nervous system based on at least one physiological signal measured from the patient and at least one known characteristic of a patient's respiration. Respiration protocol may be provided to guide characteristics of the patient's respiration. The physiological signal measured from the patient may be transformed using a wavelet transform to create a transformed signal, and a scalogram may be generated based at least in part on the transformed signal. A metric that may indicate information about the patient's autonomic nervous system may be determined from the scalogram and the known characteristic of the patient's respiration.
摘要翻译：公开了用于基于从患者测量的至少一个生理信号和患者呼吸的至少一个已知特征来确定关于患者的自主神经系统的生理信息的方法和系统。可以提供呼吸方案以指导患者呼吸的特征。可以使用小波变换来变换从患者测量的生理信号以产生变换的信号，并且可以至少部分地基于变换的信号来生成缩略图。可以指示关于患者的自主神经系统的信息的度量可以从患者呼吸的标尺和已知特征确定。

4. 发明申请

WO2010007488A1 SYSTEMS AND METHODS FOR COMPUTING A PHYSIOLOGICAL PARAMETER USING CONTINUOUS WAVELET TRANSFORMS 审中-公开
标题翻译：使用连续波段变换计算生理参数的系统和方法
公开(公告)号：WO2010007488A1
公开(公告)日：2010-01-21
申请号：PCT/IB2009/006205
申请日：2009-07-08
申请人： NELLCOR PURITAN BENNETT IRELAND , ADDISON, Paul, Stanley , WATSON, James, Nicholas
发明人： ADDISON, Paul, Stanley , WATSON, James, Nicholas
IPC分类号： A61B5/024 , G06F19/00 , A61B5/00
CPC分类号： A61B5/0059 , A61B5/02416 , A61B5/7203 , A61B5/726 , G06F19/00 , G06K9/00516 , G06K9/00536
摘要： According to embodiments, systems and methods for computing a physiological parameter are provided. The physiological parameter may be calculated using a continuous wavelet transform technique as well as using a non-continuous wavelet transform technique. More than one value for the physiological parameter may be calculated using various techniques. The values may be evaluated to select a desired value, or an average or weighted average of the values may be computed to generate a desired value.
摘要翻译：根据实施例，提供了用于计算生理参数的系统和方法。可以使用连续小波变换技术以及使用非连续小波变换技术来计算生理参数。可以使用各种技术计算生理参数的多于一个值。可以评估这些值以选择期望值，或者可以计算值的平均值或加权平均值以产生期望值。

5. 发明申请

WO2010001231A2 PROCESSING AND DETECTING BASELINE CHANGES IN SIGNALS 审中-公开
标题翻译：处理和检测信号中的基线变化
公开(公告)号：WO2010001231A2
公开(公告)日：2010-01-07
申请号：PCT/IB2009/006134
申请日：2009-06-29
申请人： NELLCOR PURITAN BENNETT IRELAND , WATSON, James, Nicholas , ADDISON, Paul, Stanley
发明人： WATSON, James, Nicholas , ADDISON, Paul, Stanley
IPC分类号： A61B5/00
CPC分类号： A61B5/7282 , A61B5/0205 , A61B5/14551 , A61B5/1495 , A61B5/6814 , A61B5/6826 , A61B5/6838 , A61B5/726 , G06F19/00 , G06F19/12 , G06F19/24 , G06F19/26 , G06F19/34 , G16H40/40
摘要： According to embodiments, systems and methods for detecting the occurrence of events from a signal are provided. A signal processing system may analyze baseline changes and changes in signal characteristics to detect events from a signal. The system may also detect events by analyzing energy parameters and artifacts in a scalogram of the signal. Further, the system may detect events by analyzing both the signal and its corresponding scalogram.
摘要翻译：根据实施例，提供了用于从信号中检测事件的发生的系统和方法。信号处理系统可以分析基线变化和信号特征的变化以检测来自信号的事件。该系统还可以通过分析信号的尺度图中的能量参数和伪像来检测事件。此外，系统可以通过分析信号及其对应的尺度图来检测事件。

6. 发明申请

WO2010001243A1 SIGNAL PROCESSING MIRRORING TECHNIQUE 审中-公开
标题翻译：信号处理仿真技术
公开(公告)号：WO2010001243A1
公开(公告)日：2010-01-07
申请号：PCT/IB2009/006153
申请日：2009-06-29
申请人： NELLCOR PURITAN BENNETT IRELAND , ADDISON, Paul, Stanley , WATSON, James, Nicholas
发明人： ADDISON, Paul, Stanley , WATSON, James, Nicholas
IPC分类号： A61B5/00
CPC分类号： A61B5/14551 , A61B5/7207 , A61B5/7225 , A61B5/7232 , A61B5/726
摘要： Embodiments may include systems and methods capable of processing an original signal by selecting and mirroring portions of the signal to create a new signal for further analysis. In an embodiment, the signal may be a photoplethysmograph (PPG) signal and the new signal may be further analyzed using continuous wavelet transforms. Any suitable number of reconstructed new signals may be created from the original signal and scalograms may be derived at least in part from the new signals. Ridges may be extracted from the scalograms of the new signals and secondary scalograms may be further derived from the ridges. A sum along amplitudes technique may be applied to a selected scalogram and may be plotted as a function of the scale of the scalogram. Desired information, such as respiration information within the original signal, may be identified from the plot.
摘要翻译：实施例可以包括能够通过选择和镜像信号的部分来处理原始信号以创建用于进一步分析的新信号的系统和方法。在一个实施例中，信号可以是光电容积描记器（PPG）信号，并且可以使用连续小波变换进一步分析新信号。可以从原始信号创建任何合适数量的重构的新信号，并且可以至少部分地从新的信号导出缩略图。可以从新信号的缩放图中提取脊，并且可以从脊进一步导出二次标尺。沿着幅度技术的和可以应用于所选择的标尺，并且可以作为缩放图的尺度的函数来绘制。可以从绘图中识别所需的信息，例如原始信号内的呼吸信息。

7. 发明申请

WO2010001232A1 SYSTEMS AND METHODS FOR DETERMINING EFFORT 审中-公开
标题翻译：用于确定效果的系统和方法
公开(公告)号：WO2010001232A1
公开(公告)日：2010-01-07
申请号：PCT/IB2009/006135
申请日：2009-06-29
申请人： NELLCOR PURITAN BENNETT IRELAND , ADDISON, Paul, Stanley , WATSON, James, Nicholas
发明人： ADDISON, Paul, Stanley , WATSON, James, Nicholas
IPC分类号： A61B5/00
CPC分类号： A61B5/08 , A61B5/0816 , A61B5/087 , A61B5/14551 , A61B5/726
摘要： According to embodiments, methods and systems for determining effort is disclosed. Effort may relate to a measure of strength of at least one repetitive feature in a signal. Effort may also relate to physical effort or work of a process (e.g., respiratory effort) that may affect the signal (e.g., a PPG signal). Effort may be determined through feature analysis of a transformed signal that has been transformed via a continuous wavelet transform. For example, respiratory effort may be determined using a scalogram generated based at least in part on a wavelet transform of a physiological signal and analyzing features of the scalogram.
摘要翻译：根据实施例，公开了用于确定努力的方法和系统。努力可能涉及信号中至少一个重复特征的强度的度量。努力还可能涉及可能影响信号（例如，PPG信号）的过程的体力或工作（例如呼吸努力）。可以通过经由连续小波变换变换的变换信号的特征分析来确定努力。例如，可以使用至少部分地基于生理信号的小波变换产生的标尺来确定呼吸努力并分析标尺的特征。

8. 发明申请

WO2011135440A1 METHODS AND APPARATUS FOR CALIBRATING RESPIRATORY EFFORT FROM PHOTOPLETHYSMOGRAPH SIGNALS 审中-公开
标题翻译：用于校准光电子信号信号的呼吸作用的方法和装置
公开(公告)号：WO2011135440A1
公开(公告)日：2011-11-03
申请号：PCT/IB2011/000906
申请日：2011-04-27
申请人： NELLCOR PURITAN BENNETT IRELAND , ADDISON, Paul, Stanley , WATSON, James, Nicholas
发明人： ADDISON, Paul, Stanley , WATSON, James, Nicholas
IPC分类号： A61B5/087 , A61B5/1455
CPC分类号： A61B5/08 , A61B5/0816 , A61B5/087 , A61B5/14551 , A61B5/4818 , A61B5/726 , A61B2560/0223
摘要： Breathing effort of a patient, as determined (for example) from a photoplethysmograph ("PPG") signal from the patient, can be calibrated in relation to air pressure in the patient's respiratory system. This calibration can be done by subjecting the patient to varying amounts of breathing resistance; and for each such amount, concurrently measuring (1) air pressure in the respiratory system (e.g., in the oral/nasal cavity) and (2) breathing effort (from the PPG signal). Use can be made of this calibration, e.g., during a sleep study of the patient. During such a study, breathing effort, again determined from the PPG signal and occurring, for example, during an apneic event of the patient, can be used to infer air pressure in the respiratory system by using the above calibration.
摘要翻译：来自患者的光电容积描记器（“PPG”）信号确定（例如）患者的呼吸能力可以相对于患者呼吸系统中的空气压力进行校准。这种校准可以通过对患者进行不同量的呼吸阻力来进行; 并且对于每个这样的量，同时测量（1）呼吸系统中的空气压力（例如在口腔/鼻腔中）和（2）呼吸努力（来自PPG信号）。可以使用这种校准，例如在患者的睡眠研究期间。在这样的研究中，呼吸的努力再次从PPG信号确定并且例如在患者的呼吸暂停事件期间发生，可以通过使用上述校准来推断呼吸系统中的气压。

9. 发明申请

WO2010038119A2 DETECTING SLEEP EVENTS USING LOCALIZED BLOOD PRESSURE CHANGES 审中-公开
标题翻译：利用局部血压变化检测睡眠事件
公开(公告)号：WO2010038119A2
公开(公告)日：2010-04-08
申请号：PCT/IB2009/006895
申请日：2009-09-17
申请人： NELLCOR PURITAN BENNETT IRELAND , WATSON, James, Nicholas , ADDISON, Paul, Stanley , SETHI, Rakesh
发明人： WATSON, James, Nicholas , ADDISON, Paul, Stanley , SETHI, Rakesh
IPC分类号： A61B5/021
CPC分类号： A61B5/021 , A61B5/0059 , A61B5/02125 , A61B5/4809 , A61B5/4812 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838
摘要： Techniques for detecting sleep events are disclosed. In some embodiments, a continuous non-invasive blood pressure ("CNIBP") monitoring system may be used to obtain blood pressure values from a subject during a sleep study. Changes in the blood pressure over time may be determined and analyzed in order to identify a sleep event. The localized blood pressure changes may be interpreted in isolation or in combination with other signals collected from the subject.
摘要翻译：公开了用于检测睡眠事件的技术。在一些实施例中，连续无创血压（“CNIBP”）监测系统可用于在睡眠研究期间从受试者获得血压值。可以确定和分析血压随时间的变化以识别睡眠事件。局部血压变化可以单独解释或与从受试者收集的其他信号一起解释。

10. 发明申请

WO2010038118A1 SYSTEM AND METHOD FOR RECALIBRATING A NON- INVASIVE BLOOD PRESSURE MONITORING SYSTEM 审中-公开
标题翻译：用于记录非入血血压监测系统的系统和方法
公开(公告)号：WO2010038118A1
公开(公告)日：2010-04-08
申请号：PCT/IB2009/006893
申请日：2009-09-17
申请人： NELLCOR PURITAN BENNETT IRELAND , BAKER, Clark, R., Jr. , ADDISON, Paul, Stanley , WATSON, James, Nicholas
发明人： BAKER, Clark, R., Jr. , ADDISON, Paul, Stanley , WATSON, James, Nicholas
IPC分类号： A61B5/021 , A61B8/04
CPC分类号： A61B5/021 , A61B5/02125 , A61B5/022 , A61B5/02225 , A61B5/1455 , A61B5/7239 , A61B2560/0223 , G16H15/00 , G16H40/40 , G16H40/63
摘要： Techniques for non-invasive blood pressure monitoring are disclosed. Data corresponding to a patient may be received from a hospital information system. The data may include, for example, drug administration data, medical procedure data, medical equipment data, or a combination thereof. Whether a blood pressure monitoring system needs to be recalibrated may be determined, based at least in part on the received data. If it is determined that the blood pressure monitoring system needs to be recalibrated, the recalibration may be performed and at least one blood pressure measurement of the patient may be computed using the recalibrated blood pressure monitoring system.
摘要翻译：公开了用于非侵入性血压监测的技术。可以从医院信息系统接收对应于患者的数据。数据可以包括例如药物管理数据，医疗程序数据，医疗设备数据或其组合。至少部分地基于所接收的数据，可以确定是否需要重新校准血压监测系统。如果确定需要重新校准血压监测系统，则可以执行重新校准，并且可以使用重新校准的血压监测系统来计算患者的至少一个血压测量值。

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