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1. 发明申请

WO2009145632A1 AN INSTRUMENT FOR MINIMALLY INVASIVE SURGERY 审中-公开
标题翻译：最小手术手术仪器
公开(公告)号：WO2009145632A1
公开(公告)日：2009-12-03
申请号：PCT/NL2009/050299
申请日：2009-05-29
申请人： NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO , VLEUGELS HOLDING B.V. , VAN DEN DOOL, Teunis Cornelis , KRAMER, Geerten Frans Ijsbrand , TABAK, Erik , ODERWALD, Michiel Peter
发明人： VAN DEN DOOL, Teunis Cornelis , KRAMER, Geerten Frans Ijsbrand , TABAK, Erik , ODERWALD, Michiel Peter
IPC分类号： A61B17/00
CPC分类号： A61B17/29 , A61B2017/2939 , A61B2017/294 , A61B2090/065
摘要： The invention relates to an instrument, preferably for minimally invasive surgery,comprising a frame (27) having a proximal end and a distal end, a first working element (4) having a first origin located at the distal end and a second working element (5) having a second origin and being arranged at the distal end cooperating with the first working element, a force sensor for measuring a force exerted on at least one of the saidthe first and the second working elements, wherein the distal end of the frame comprises an opening (23) between the first origin and the second origin, the force sensor being arranged on the frame in a vicinity of the opening.
摘要翻译：本发明涉及一种优选用于微创手术的器械，包括具有近端和远端的框架（27），具有位于远端的第一原点的第一工作元件（4）和第二工作元件（ 5）具有第二原点并且布置在与第一工作元件配合的远端处;力传感器，用于测量施加在所述第一和第二工作元件中的至少一个上的力，其中框架的远端包括在第一原点和第二原点之间的开口（23），力传感器布置在开口附近的框架上。

2. 发明申请

WO2009139628A1 A VIBRATION SENSOR AND A SYSTEM TO ISOLATE VIBRATIONS 审中-公开
标题翻译：振动传感器和隔离振动的系统
公开(公告)号：WO2009139628A1
公开(公告)日：2009-11-19
申请号：PCT/NL2009/050256
申请日：2009-05-14
申请人： NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO , FRAANJE, Petrus Rufus , RIJNVELD, Niek , VAN DEN DOOL, Teunis Cornelis
发明人： FRAANJE, Petrus Rufus , RIJNVELD, Niek , VAN DEN DOOL, Teunis Cornelis
IPC分类号： F16F15/02 , F16F7/10
CPC分类号： F16F15/02 , F16F7/1005
摘要： A vibration sensor (9) comprises a reference mass (10), a resilient element (11) supporting the reference mass (10), and a base (13) supporting the resilient element (11), and further comprises a displacement sensor (12) for determining the distance between the reference mass (10) and the base (13). In accordance with the invention the vibration sensor comprises an actuator (14) that is situated between the resilient element (11) and the base (13), a second displacement sensor (15), and a controller (16) for providing an output signal to the actuator (14)
摘要翻译：振动传感器（9）包括参考质量（10），支撑参考质量块（10）的弹性元件（11）和支撑弹性元件（11）的基座（13），并且还包括位移传感器），用于确定参考质量（10）和基座（13）之间的距离。根据本发明，振动传感器包括位于弹性元件（11）和基座（13）之间的致动器（14），第二位移传感器（15）和用于提供输出信号的控制器（16）到致动器（14）

3. 发明申请

WO2010143959A1 AN ACTIVE VIBRATION ISOLATION AND DAMPING SYSTEM 审中-公开
标题翻译：主动振动隔离和阻尼系统
公开(公告)号：WO2010143959A1
公开(公告)日：2010-12-16
申请号：PCT/NL2010/050360
申请日：2010-06-11
申请人： NEDERLANDSE ORGANISATIE VOOR TOEGEPAST- NATUURWETENSCHAPPELIJK ONDERZOEK TNO , RIJNVELD, Niek , VAN DEN DOOL, Teunis Cornelis
发明人： RIJNVELD, Niek , VAN DEN DOOL, Teunis Cornelis
IPC分类号： F16F15/02 , G05D19/02
CPC分类号： F16F15/02 , G05D19/02
摘要： An active vibration isolation and damping system (11) comprising a payload (12) that has to be isolated or damped, a vibration sensor (14) for detecting a vibration of the payload, an actuator (15) for moving the payload relative to a bearing body (13) supporting the payload, and a controller (16) for providing the actuator with a signal that is representative for the vibration. The system provides a solution for the tilting problem by applying a vibration sensor that has a low stiffness connection to the payload (12) for rotation along an axis (17) perpendicular to the gravitational force (18), and a high stiffness connection to the payload (12) for the vibration detectable with the vibration sensor.
摘要翻译：包括必须隔离或阻尼的有效载荷（12）的主动隔振和阻尼系统（11），用于检测有效负载的振动的振动传感器（14），用于相对于支撑有效载荷的轴承体（13），以及用于向致动器提供代表振动的信号的控制器（16）。该系统通过应用具有与负载（12）的低刚度连接的振动传感器来提供用于倾斜问题的解决方案，用于沿垂直于重力（18）的轴线（17）旋转，并且与用于振动传感器可检测的振动的有效载荷（12）。

4. 发明授权

EP2291124B1 AN INSTRUMENT FOR MINIMALLY INVASIVE SURGERY 有权转让
标题翻译：一种微创外科手术器械
公开(公告)号：EP2291124B1
公开(公告)日：2017-07-05
申请号：EP09755089.1
申请日：2009-05-29
申请人： Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO , Vleugels Holding B.V.
发明人： VAN DEN DOOL, Teunis Cornelis , KRAMER, Geerten Frans Ijsbrand , TABAK, Erik , ODERWALD, Michiel Peter
IPC分类号： A61B17/00
CPC分类号： A61B17/29 , A61B2017/2939 , A61B2017/294 , A61B2090/065
摘要： The invention relates to an instrument, preferably for minimally invasive surgery, comprising a frame (27) having a proximal end and a distal end, a first working element (4) having a first origin located at the distal end and a second working element (5) having a second origin and being arranged at the distal end cooperating with the first working element, a force sensor for measuring a force exerted on at least one of the said the first and the second working elements, wherein the distal end of the frame comprises an opening (23) between the first origin and the second origin, the force sensor being arranged on the frame in a vicinity of the opening.
摘要翻译：本发明涉及一种优选用于微创手术的器械，其包括具有近端和远端的框架（27），具有位于远端的第一原点的第一工作元件（4）和位于远端的第二工作元件（ 5）具有第二原点并且布置在与第一工作元件配合的远端处;力传感器，用于测量施加在所述第一工作元件和第二工作元件中的至少一个上的力，其中，框架的远端包括位于所述第一原点和所述第二原点之间的开口（23），所述力传感器布置在所述框架上的所述开口附近。

5. 发明公开

EP2291124A1 AN INSTRUMENT FOR MINIMALLY INVASIVE SURGERY 有权转让
标题翻译：仪器开刀手术极小
公开(公告)号：EP2291124A1
公开(公告)日：2011-03-09
申请号：EP09755089.1
申请日：2009-05-29
申请人： Nederlandse Organisatie voor Toegepast -Natuurwetenschappelijk Onderzoek TNO , Vleugels Holding B.V.
发明人： VAN DEN DOOL, Teunis Cornelis , KRAMER, Geerten Frans Ijsbrand , TABAK, Erik , ODERWALD, Michiel Peter
IPC分类号： A61B17/00
CPC分类号： A61B17/29 , A61B2017/2939 , A61B2017/294 , A61B2090/065
摘要： The invention relates to an instrument, preferably for minimally invasive surgery, comprising a frame (27) having a proximal end and a distal end, a first working element (4) having a first origin located at the distal end and a second working element (5) having a second origin and being arranged at the distal end cooperating with the first working element, a force sensor for measuring a force exerted on at least one of the said the first and the second working elements, wherein the distal end of the frame comprises an opening (23) between the first origin and the second origin, the force sensor being arranged on the frame in a vicinity of the opening.

6. 发明申请

WO2016003281A1 SYSTEM AND METHOD OF PERFORMING SCANNING PROBE MICROSCOPY ON A SUBSTRATE SURFACE 审中-公开
标题翻译：在基板表面上执行扫描探针显微镜的系统和方法
公开(公告)号：WO2016003281A1
公开(公告)日：2016-01-07
申请号：PCT/NL2015/050487
申请日：2015-07-03
申请人： NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO
发明人： SADEGHIAN MARNANI, Hamed , WINTERS, Jasper , CROWCOMBE, William Edward , VAN DEN DOOL, Teunis Cornelis , KRAMER, Geerten Frans Ijsbrand
IPC分类号： G01Q10/06 , G01Q70/02
CPC分类号： G01Q10/04 , B82Y35/00 , G01Q10/06 , G01Q70/02 , G01Q70/06
摘要： The invention is directed at a method of performing scanning probe microscopy on a substrate surface using a scanning probe microscopy system, the system including at least one probe head, the probe head comprising a probe tip arranged on a cantilever and a tip position detector for determining a position of the probe tip along a z- direction transverse to an image plane, the method comprising: positioning the at least one probe head relative to the substrate surface; moving the probe tip and the substrate surface relative to each other in one or more directions parallel to the image plane for scanning of the substrate surface with the probe tip; and determining the position of the probe tip with the tip position detector during said scanning for mapping nanostructures on the substrate surface; wherein said step of positioning is performed by placing the at least one probe head on a static carrier surface.
摘要翻译：本发明涉及使用扫描探针显微镜系统在衬底表面上执行扫描探针显微术的方法，所述系统包括至少一个探针头，探头包括布置在悬臂上的探针尖和用于确定的尖端位置检测器所述探针尖端沿着横向于图像平面的z方向的位置，所述方法包括：相对于所述衬底表面定位所述至少一个探针头; 在一个或多个平行于图像平面的方向上相对于彼此移动探针尖端和基底表面，用于用探针尖端扫描基底表面; 以及在所述扫描期间确定所述探针尖端与所述尖端位置检测器的位置，以在所述衬底表面上绘制纳米结构; 其中所述定位步骤通过将所述至少一个探针头放置在静态载体表面上而进行。

7. 发明申请

WO2016003282A1 METHOD OF POSITIONING A CARRIER ON A FLAT SURFACE, AND ASSEMBLY OF A CARRIER AND AN POSITIONING MEMBER 审中-公开
标题翻译：在平坦表面上定位载体的方法，以及载体和定位构件的组装
公开(公告)号：WO2016003282A1
公开(公告)日：2016-01-07
申请号：PCT/NL2015/050488
申请日：2015-07-03
申请人： NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO
发明人： SADEGHIAN MARNANI, Hamed , WINTERS, Jasper , CROWCOMBE, William Edward , VAN DEN DOOL, Teunis Cornelis , KRAMER, Geerten Frans Ijsbrand , DEKKER, Albert
IPC分类号： G01Q70/02 , B23Q1/26 , B23Q16/00 , F16M7/00 , F16M11/04
CPC分类号： G01Q70/02 , F16M7/00 , F16M11/043 , F16M11/18 , F16M11/2085 , F16M11/2092 , F16M11/24 , F16M2200/08
摘要： Method of positioning a carrier on a flat surface, and assembly of a carrier and an positioning member. The invention is about a method of positioning a carrier on a flat surface using an positioning member, wherein the carrier comprises an upper part and a base, wherein the positioning member is arranged between the base and the upper part, wherein the upper part comprises three engagement elements, and wherein the positioning member comprises a support surface including a plurality of sockets forming a kinematic mount for said three engagement elements, the method comprising the steps of: performing an action of placing the carrier on the flat surface at a landing position.
摘要翻译：将载体定位在平坦表面上的方法，以及载体和定位构件的组装。本发明涉及一种使用定位构件将载体定位在平坦表面上的方法，其中载体包括上部和底部，其中定位构件布置在基部和上部之间，其中上部包括三个接合元件，并且其中所述定位构件包括支撑表面，所述支撑表面包括形成用于所述三个接合元件的运动安装座的多个插座，所述方法包括以下步骤：执行将所述托架放置在平坦表面处于着陆位置的动作。

8. 发明申请

WO2014003557A1 HIGH THROUGHPUT MICROSCOPY DEVICE 审中-公开
标题翻译：高速显微镜装置
公开(公告)号：WO2014003557A1
公开(公告)日：2014-01-03
申请号：PCT/NL2013/050459
申请日：2013-06-27
申请人： NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO
发明人： VAN DEN BRABER, Rens , VAN DEN DOOL, Teunis Cornelis , SADEGHIAN MARNANI, Hamed , RIJNVELD, Niek
IPC分类号： G01Q10/06 , G01Q70/06 , B82Y35/00
CPC分类号： G01Q20/00 , G01Q10/06 , G01Q70/06
摘要： An object is mounted on a surface of a sample carrier. Properties of the surface of the object are measured and/or modified by means of a plurality of independently movable heads, each comprising a microscopic probe. The heads being located between the surface of a reference grid plate and the surface of the sample carrier. Head specific target locations are selected for the heads. Each head is moved over the surface of the reference grid plate, to the target location of the head. During movement a position of the head is determined from markings on the reference grid plate sensed by sensor in the head. When the sensor has indicated that the head is at the target location selected for the head a force between the head and the reference grid plate is switched to seat and/or clamp the head on the reference grid plate.
摘要翻译：物体安装在样品载体的表面上。通过多个可独立移动的头来测量和/或修改物体表面的特性，每个头包括微观探针。头部位于参考栅格板的表面和样品载体的表面之间。头部具体目标位置被选择。每个头部移动到参考格栅板的表面，到头部的目标位置。在运动期间，头部的位置由头部中由传感器感测到的参考网格板上的标记确定。当传感器已经指示头部位于为头部选择的目标位置时，头部和参考格栅板之间的力被切换以将头部安置和/或夹紧在参考格栅板上。

9. 发明申请

WO2015167326A1 METHOD OF ADVANCING A PROBE TIP OF A SCANNING MICROSCOPY DEVICE TOWARDS A SAMPLE SURFACE, AND DEVICE THEREFORE 审中-公开
标题翻译：提取样品表面的扫描显微镜装置的探针提取方法及其装置
公开(公告)号：WO2015167326A1
公开(公告)日：2015-11-05
申请号：PCT/NL2015/050281
申请日：2015-04-28
申请人： NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO
发明人： SADEGHIAN MARNANI, Hamed , KRAMER, Geerten Frans Ijsbrand , VAN DEN DOOL, Teunis Cornelis
IPC分类号： G01Q10/06
CPC分类号： G01Q10/06 , B82Y35/00
摘要： The invention is directed at a method of advancing a probe tip of a probe of a scanning microscopy device towards a sample surface. The scanning microscopy device comprises the probe for scanning the sample surface for mapping nanostructures on the sample surface. The probe tip of the probe is mounted on a cantilever arranged for bringing the probe tip in contact with the sample surface. The method comprises controlling, by a controller, an actuator system of the device for moving the probe to the sample surface, and receiving, by the controller, a sensor signal indicative of at least one operational parameter of the probe for providing feedback to perform said controlling. The method further comprises maintaining, during said controlling, an electric field between the sample surface and the probe tip, and evaluating the sensor signal indicative of the at least one operational parameter for determining an influence on said probe by said electric field, for determining proximity of the sample surface relative to the probe tip. The invention is further directed at a scanning microscopy device comprising a probe for scanning a sample surface for mapping nanostructures thereon.
摘要翻译：本发明涉及一种将扫描显微镜装置的探针的探针尖端推向样品表面的方法。扫描显微镜装置包括用于扫描样品表面的探针，用于在样品表面上绘制纳米结构。探针的探针尖端安装在悬臂上，用于使探针尖端与样品表面接触。该方法包括由控制器控制该装置的致动器系统，用于将探针移动到样品表面，以及由控制器接收指示探针的至少一个操作参数的传感器信号，以提供反馈以执行所述控制。所述方法还包括在所述控制期间保持样品表面和探针尖端之间的电场，以及评估指示所述至少一个操作参数的传感器信号，以通过所述电场确定对所述探针的影响，以确定接近度的样品表面相对于探针尖端。本发明还涉及一种扫描显微镜装置，其包括用于扫描样品表面的探针，用于在其上绘制纳米结构。

10. 发明申请

WO2017105240A1 HIGH POWER ADAPTIVE MIRROR 审中-公开
标题翻译：高功率自适应镜子
公开(公告)号：WO2017105240A1
公开(公告)日：2017-06-22
申请号：PCT/NL2016/050883
申请日：2016-12-16
申请人： NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO
发明人： VAN ZWET, Erwin John , VAN DEN DOOL, Teunis Cornelis , NIEUWKOOP, Evert
IPC分类号： G02B26/06 , G02B26/08
CPC分类号： G02B26/0825 , G02B26/06 , G02B26/0841 , G02B26/0866
摘要： According to an aspect of the invention, there is provided a mirror structure for adaptive optics devices, characterized in that it comprises: an elastically deformable layer in response to an applied force, said deformable layer comprising a central portion reflective to said an incident light beam (F); a support substrate positioned spaced with respect to said deformable layer; a spacer element connected to said elastically deformable layer and support substrate and positioned there between, said spacer element being arranged so that the separation distance between said first and second inner surface is in the range between 2 and 100 micron; an inner chamber at least partially defined by said first and substrate and by said spacer element, said inner chamber containing a pressurized gas (G); an actuator system capable of causing a deformation of said central portion counteracting the pressure of said pressurized gas; wherein, in use, said central portion is deformed according to profiles such as to control said light beam. Advantages may include thermal robustness and improved dimensional scaling properties.
摘要翻译：根据本发明的一个方面，提供了一种用于自适应光学装置的反射镜结构，其特征在于其包括：响应于所施加的力的可弹性变形层，所述可变形层包括中央对所述入射光束（F）反射的部分; 相对于所述可变形层间隔设置的支撑基板; 连接到所述可弹性变形层和支撑衬底并定位在其间的间隔元件，所述间隔元件布置成使得所述第一和第二内表面之间的分隔距离在2和100微米之间的范围内; 至少部分地由所述第一和衬底以及所述隔离元件限定的内室，所述内室包含加压气体（G）; 致动器系统，所述致动器系统能够引起所述中心部分的变形抵消所述加压气体的压力; 其中在使用中，所述中央部分根据轮廓变形以控制所述光束。优势可能包括热稳定性和改进的尺寸缩放性能。

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