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    • 2. 发明申请
    • HYBRID OF ITRACONAZOLE, CYCLOSPORINE OR CARVEDILOL WITH A LAYERED SILICATE AND A PROCESS FOR PREPARING THE SAME
    • 具有层状硅酸盐的异烟肼,环磷酰胺或卡维地洛的混合物及其制备方法
    • WO2004009120A1
    • 2004-01-29
    • PCT/KR2003/001449
    • 2003-07-22
    • NANOHYBRID CO., LTD.PARK, Tae-UnJUNG, HyunKIM, Hyun-MiCHOY, Jin-HoLEE, Chi-Won
    • PARK, Tae-UnJUNG, HyunKIM, Hyun-MiCHOY, Jin-HoLEE, Chi-Won
    • A61K47/02
    • A61K31/403A61K9/143A61K31/496A61K38/13
    • The present invention provides the hybrids wherein itraconazole, cyclosporine or carvedilol are intercalated into the interlayers and/or absorbed onto the surfaces of layered silicates. The hybrids according to the present invention enable the maximization of bioavailability of drugs by dissolving the drugs from the layered silicates. Furthermore, the present invention provides the preparing methods of the hybrids. The process comprises: (1) dispersing a layered silicate in an aqueous solution to form an aqueous solution containing the layered silicate; (2) dissolving a drug in a organic solvent to form an organic solution containing the drug, the organic solvent having a solubility higher than that in the aqueous solution; and (3) mixing and hybridizing in the inerrface of the aqueous solution containing the layered silicate and the organic phase solution containing the drug in order to intercalate the drug into the interlayers of the layered silicate and/or to absorb the drug onto the surface of the layered silicate.
    • 本发明提供了伊曲康唑,环孢菌素或卡维地洛插入中间层和/或吸收到层状硅酸盐表面上的杂交体。 根据本发明的杂交体能够通过从层状硅酸盐中溶解药物使药物的生物利用度最大化。 此外,本发明提供了杂种的制备方法。 该方法包括:(1)将层状硅酸盐分散在水溶液中以形成含有层状硅酸盐的水溶液; (2)将药物溶解在有机溶剂中以形成含有药物的有机溶液,所述有机溶剂的溶解度高于所述水溶液中的溶解度; 和(3)在含有层状硅酸盐的水溶液和含有药物的有机相溶液的表面中混合和杂交,以将药物插入层状硅酸盐的夹层中和/或将药物吸收到 层状硅酸盐。
    • 3. 发明公开
    • HYBRID OF ITRACONAZOLE, CYCLOSPORINE OR CARVEDILOL WITH A LAYERED SILICATE AND A PROCESS FOR PREPARING THE SAME
    • 具有层状硅酸盐的ITRACONAZOLE,CYCLOSPORINE或CARVILILOL的混合物及其制备方法
    • EP1542728A1
    • 2005-06-22
    • EP03765386.2
    • 2003-07-22
    • Nanohybrid Co., Ltd.
    • PARK, Tae-UnJUNG, HyunKIM, Hyun-MiCHOY, Jin-HoLEE, Chi-Won
    • A61K47/02
    • A61K31/403A61K9/143A61K31/496A61K38/13
    • The present invention provides the hybrids wherein itraconazole, cyclosporine or carvedilol are intercalated into the interlayers and/or absorbed onto the surfaces of layered silicates. The hybrids according to the present invention enable the maximization of bioavailability of drugs by dissolving the drugs from the layered silicates. Furthermore, the present invention provides the preparing methods of the hybrids. The process comprises: (1) dispersing a layered silicate in an aqueous solution to form an aqueous solution containing the layered silicate; (2) dissolving a drug in a organic solvent to form an organic solution containing the drug, the organic solvent having a solubility higher than that in the aqueous solution; and (3) mixing and hybridizing in the inerrface of the aqueous solution containing the layered silicate and the organic phase solution containing the drug in order to intercalate the drug into the interlayers of the layered silicate and/or to absorb the drug onto the surface of the layered silicate.
    • 本发明提供了其中伊曲康唑,环孢菌素或卡维地洛嵌入中间层和/或吸附到层状硅酸盐表面上的杂交物。 根据本发明的杂交体能够通过从层状硅酸盐中溶解药物来使药物的生物利用度最大化。 此外,本发明提供了杂种的制备方法。 该方法包括:(1)将层状硅酸盐分散在水溶液中以形成含有层状硅酸盐的水溶液; (2)将药物溶解在有机溶剂中以形成含有药物的有机溶液,有机溶剂的溶解度高于水溶液中的溶解度; (3)在含有层状硅酸盐的水溶液和含有药物的有机相溶液的界面混合和杂交,以便将药物插入层状硅酸盐的夹层中和/或将药物吸附到 层状硅酸盐。
    • 4. 发明申请
    • CENTRAL ANTENNA MANAGEMENT SYSTEM WITH CENTRALIZED DATABASE
    • 具有中央数据库的中央天线管理系统
    • WO2009097282A1
    • 2009-08-06
    • PCT/US2009/032133
    • 2009-01-27
    • KMW U.S.A., INC.JUNG, HyunKIM, Duk-YongKIM, Yeung
    • JUNG, HyunKIM, Duk-YongKIM, Yeung
    • H04B7/04H04B7/155G06F17/30
    • H04L41/22H01Q1/246H01Q3/005H01Q3/08H01Q3/30H04L41/0816H04L41/0856H04W24/02
    • An antenna management system is disclosed for managing cellular communications network antennas remotely in response to traffic demands and environmental factors, including a packet switching network, antennas, base transceiver stations, tilt controllers, air interface modules, a management database, and a control network. In the exemplary embodiment, the system utilizes feedback from a variety of sensors including downtilt sensors, azimuth sensors, weather sensors, gas sensors, and a camera. The system enables data from the sensors to be viewed remotely and analyzed to determine if corrective adjustment of the antenna(s) is needed. After analyzing the data, the system or a user of the system such as a network operator can remotely adjust the antenna(s) to make necessary adjustment(s). The system further enables data received from the sensors to be made available over a packet switching network, such as the Internet or a local or wide area network, to any device, such as a computer or mobile station, connected to the packet switching network.
    • 公开了一种用于响应于业务需求和环境因素来远程管理蜂窝通信网络天线的天线管理系统,包括分组交换网络,天线,基站收发台,倾斜控制器,空中接口模块,管理数据库和控制网络。 在示例性实施例中,系统利用来自各种传感器的反馈,包括下倾传感器,方位传感器,气象传感器,气体传感器和照相机。 该系统允许远程查看来自传感器的数据并进行分析,以确定是否需要对天线进行校正调整。 在分析数据之后,诸如网络运营商的系统或系统的用户可以远程调整天线以进行必要的调整。 该系统还使得可以通过分组交换网络(例如因特网或本地或广域网)将从传感器接收的数据提供给连接到分组交换网络的任何设备,例如计算机或移动站。