会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 9. 发明申请
    • IMMUNITY INDUCER
    • 免疫电感
    • US20130183356A1
    • 2013-07-18
    • US13812000
    • 2011-07-28
    • Jinyan ChengKouji Maruyama
    • Jinyan ChengKouji Maruyama
    • A61K33/42
    • A61K33/42A61K9/0024A61K9/2095
    • The purpose is to provide an immunity-inducing agent which can be implanted or injected in vivo by a simple operation and is capable of activating the in vivo immunological actions without causing adverse side effects. An immunity-inducing agent comprising β-tricalcium phosphate (β-TCP) having a porosity of 50% or less is implanted or injected in vivo, particularly in the vicinity of a lesion area (non-lesion area) such as cancer. Lymphocytes such as T cells, B cells and NK cells or a dendritic cell can be induced in the vicinity of β-TCP, and a lymphadenoid tissue is formed in which lymphocytes are localized at a high density. Examples of the dosage form of the immunity-inducing agent include particles or granules having a particle or grain size of equal to or greater than 0.05 μm and less than 25 μm, as well as tablets or columellas.
    • 其目的是提供能够通过简单操作在体内植入或注射的免疫诱导剂,并且能够激活体内免疫学作用而不引起不良副作用。 具有孔隙率为50%以下的β-磷酸三钙(β-TCP)的免疫诱导剂在体内植入或注射,特别是在病变区域(非损伤区域)如癌症附近。 可以在β-TCP附近诱导淋巴细胞如T细胞,B细胞和NK细胞或树突状细胞,并且形成淋巴细胞以高密度定位的淋巴细胞组织。 免疫诱导剂的剂型的实例包括具有等于或大于0.05μm和小于25μm的颗粒或颗粒的颗粒或颗粒,以及片剂或花粉。