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1. 发明授权

US08470056B2 Non-aqueous electrolyte secondary battery and method for producing the same 有权
标题翻译：非水电解质二次电池及其制造方法
公开(公告)号：US08470056B2
公开(公告)日：2013-06-25
申请号：US12307644
申请日：2008-01-23
申请人： Mitsuhiro Takeno , Hideki Sano , Akira Iguchi
发明人： Mitsuhiro Takeno , Hideki Sano , Akira Iguchi
IPC分类号： H01M4/04
CPC分类号： H01M10/052 , H01M4/139 , Y10T29/49108
摘要： The method for producing a non-aqueous electrolyte secondary battery of the invention includes: (a) a step of preparing an electrode mixture slurry, (b) an ionization step of oxidizing and ionizing a metal impurity present in the electrode mixture slurry, and (c) a step of producing an electrode by using the electrode mixture slurry after the ionization step. In the invention, when the electrode mixture is in the form of a slurry, the metal impurity contained in the electrode mixture is ionized to minimize the amount of the impurity. Therefore, the invention can provide a highly reliable non-aqueous electrolyte secondary battery while minimizing a decrease in production yield by the metal impurity.
摘要翻译：本发明的非水电解质二次电池的制造方法包括：（a）制备电极混合浆料的步骤，（b）氧化电离混合浆料中存在的金属杂质的离子化步骤，和 c）通过在电离步骤之后使用电极混合物浆料来生产电极的步骤。在本发明中，当电极混合物为浆料时，电极混合物中所含的金属杂质被电离以最小化杂质的量。因此，本发明可以提供高可靠性的非水电解质二次电池，同时使金属杂质的产率降低最小化。

2. 发明申请

US20090288289A1 NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY AND METHOD FOR PRODUCING THE SAME 有权
标题翻译：非水电解质二次电池及其制造方法
公开(公告)号：US20090288289A1
公开(公告)日：2009-11-26
申请号：US12307644
申请日：2008-01-23
申请人： Mitsuhiro Takeno , Hideki Sano , Akira Iguchi
发明人： Mitsuhiro Takeno , Hideki Sano , Akira Iguchi
IPC分类号： H01M4/04
CPC分类号： H01M10/052 , H01M4/139 , Y10T29/49108
摘要： The method for producing a non-aqueous electrolyte secondary battery of the invention includes: (a) a step of preparing an electrode mixture slurry, (b) an ionization step of oxidizing and ionizing a metal impurity present in the electrode mixture slurry, and (c) a step of producing an electrode by using the electrode mixture slurry after the ionization step. In the invention, when the electrode mixture is in the form of a slurry, the metal impurity contained in the electrode mixture is ionized to minimize the amount of the impurity. Therefore, the invention can provide a highly reliable non-aqueous electrolyte secondary battery while minimizing a decrease in production yield by the metal impurity.
摘要翻译：本发明的非水电解质二次电池的制造方法包括：（a）制备电极混合浆料的步骤，（b）氧化电离混合浆料中存在的金属杂质的离子化步骤，和 c）通过在电离步骤之后使用电极混合物浆料来生产电极的步骤。在本发明中，当电极混合物为浆料时，电极混合物中所含的金属杂质被电离以最小化杂质的量。因此，本发明可以提供高可靠性的非水电解质二次电池，同时使金属杂质的产率降低最小化。

3. 发明授权

US09553299B2 Lithium-ion secondary battery 有权
标题翻译：锂离子二次电池
公开(公告)号：US09553299B2
公开(公告)日：2017-01-24
申请号：US14235471
申请日：2011-07-29
申请人： Koji Takahata , Hideki Sano
发明人： Koji Takahata , Hideki Sano
IPC分类号： H01M4/587 , H01M4/04 , H01M4/133 , H01M4/1393 , H01M4/36 , H01M10/0525
CPC分类号： H01M4/0404 , H01M4/133 , H01M4/1393 , H01M4/364 , H01M4/587 , H01M10/0525 , Y02E60/122 , Y02P70/54 , Y02T10/7011
摘要： A negative electrode sheet of a lithium-ion secondary battery has a negative electrode current collector and a negative electrode active material layer on the negative electrode current collector. The negative electrode active material layer contains flake graphite particles and has a first region neighboring the negative electrode current collector and a second region neighboring a surface side that are different in perpendicularity of the graphite particles. The perpendicularity of the graphite particles is defined as (m1/m2), where, when the inclination θn of each of the graphite particles is specified relative to a surface of the negative electrode current collector, m1 is the number of the graphite particles having an inclination θn of 60°≦θn≦90° and m2 is the number of the graphite particles having an inclination θn of 0°≦θn≦30°.
摘要翻译：锂离子二次电池的负极片在负极集电体上具有负极集电体和负极活性物质层。负极活性物质层含有片状石墨粒子，具有与负极集电体相邻的第一区域和与石墨粒子的垂直度不同的与表面侧相邻的第二区域。石墨颗粒的垂直度定义为（m1 / m2），其中当相对于负极集电体的表面规定每个石墨颗粒的倾斜度θn时，m1是具有倾角θn为60°≤θn≤90°，m2为倾斜度θn为0°≤θn≤30°的石墨颗粒的数量。

4. 发明授权

US09059436B2 Method for producing lithium ion secondary battery with tap density and electrode density 有权
标题翻译：具有振实密度和电极密度的锂离子二次电池的制造方法
公开(公告)号：US09059436B2
公开(公告)日：2015-06-16
申请号：US13881769
申请日：2010-10-27
申请人： Koji Takahata , Hideki Sano
发明人： Koji Takahata , Hideki Sano
IPC分类号： H01M4/133 , H01M4/04 , H01M4/13 , H01M4/139 , H01M4/587 , H01M10/052 , H01M10/0566 , H01M4/02 , H01M4/62
CPC分类号： H01M4/04 , H01M4/0404 , H01M4/13 , H01M4/133 , H01M4/139 , H01M4/587 , H01M4/622 , H01M10/052 , H01M10/0566 , H01M2004/027 , Y02E60/122 , Y02P70/54 , Y02T10/7011 , Y10T29/49115
摘要： A method for producing a lithium-ion secondary battery comprising positive and negative electrodes and a non-aqueous electrolyte solution is provided. The method comprises (A) with several different negative electrode active materials, determining density Xn (g/cm3) at several different number of taps applied, n, respectively; (B) determining density Y (g/cm3) of a negative electrode active material layer constituted with a mixture comprising each negative electrode active material; (C) based on a regression line, Y=aXn+b, determining the number of taps applied, n′, that gives a≦0.5 and a determination coefficient R2≧0.99; (D) based on a plot of Y=aXn′+b, determining a passing range of Xn′ where negative electrode active material layer density Y is in a prescribed range; (E) selecting a negative electrode active material having Xn′in the passing range, and fabricating a negative electrode with this material.
摘要翻译：提供了一种包括正极和负极和非水电解质溶液的锂离子二次电池的制造方法。该方法包括（A）几种不同的负极活性物质，分别在几个不同的抽头数量n上确定密度Xn（g / cm3）。（B）确定由包含各负极活性物质的混合物构成的负极活性物质层的密度Y（g / cm 3）（C）基于回归线，Y = aXn + b，确定施加的抽头数，n'，其给出＆nlE; 0.5，确定系数R2≥0.99; （D）基于Y = aXn'+ b的图，确定负极活性物质层密度Y在规定范围内的Xn'的通过范围; （E）选择在通过范围内具有Xn'的负极活性物质，并用该材料制造负极。

5. 发明申请

US20140349189A1 LITHIUM SECONDARY BATTERY 有权
标题翻译：锂二次电池
公开(公告)号：US20140349189A1
公开(公告)日：2014-11-27
申请号：US14366849
申请日：2011-12-21
申请人： Koji Takahata , Hideki Sano
发明人： Koji Takahata , Hideki Sano
IPC分类号： H01M10/0583 , H01M4/587 , H01M10/0525 , H01M4/133
CPC分类号： H01M10/0583 , B60L11/18 , B60L11/1862 , B60L11/1879 , H01M4/133 , H01M4/366 , H01M4/587 , H01M10/0525 , H01M10/0587 , H01M2004/027 , Y02E60/122 , Y02T10/7011 , Y02T10/7044 , Y02T10/705
摘要： A lithium secondary battery 10 of the present invention is a secondary battery provided with a positive electrode 30 having a positive electrode active material layer 34 on a positive electrode collector 32, and a negative electrode 50 having a negative electrode active material layer 54 on a negative electrode collector 52. The positive electrode active material layer 34 contains a positive electrode active material capable of reversibly storing and releasing lithium ions. The negative electrode active material layer 54 contains a negative electrode active material made up of lamellar graphite that is bent so as to have an average number of bends f per particle of 0
摘要翻译：本发明的锂二次电池10是具有在正极集电体32上具有正极活性物质层34的正极30的二次电池，负极50具有负极活性物质层54的负极正极活性物质层34含有可逆地储存和释放锂离子的正极活性物质。负极活性物质层54含有由层状石墨构成的负极活性物质，该负极活性物质被弯曲成具有每个颗粒的平均弯曲数f为0

6. 发明授权

US07696339B2 Nucleic acid encoding monkey QRFP 失效
标题翻译：编码猴QRFP的核酸
公开(公告)号：US07696339B2
公开(公告)日：2010-04-13
申请号：US12215324
申请日：2008-06-26
申请人： Hideki Sano , Hisashi Iwaasa , Satoshi Mashiko
发明人： Hideki Sano , Hisashi Iwaasa , Satoshi Mashiko
IPC分类号： C07H21/04 , C07K14/435
CPC分类号： C07K14/705 , G01N33/6893 , G01N33/6896 , G01N2333/726
摘要： There are provided non-human primate and rat GPR103 genes and proteins and a compound evaluation method employing the genes or proteins. There are also provided highly useful novel ligands for functional analysis of the GPR103 genes and proteins and for the compound evaluation. The nucleic acids or proteins having the sequences listed as SEQ ID NOS: 1 to 4 provide non-human primate or rat GPR103 genes and proteins and information based on the genes and proteins. The genes and proteins can be used for evaluation of compounds. The nucleic acids or proteins having the sequence listed as SEQ ID NO: 5 or 6 provide a GPR103 ligand.
摘要翻译：提供了非人灵长类动物和大鼠GPR103基因和蛋白质，以及使用基因或蛋白质的化合物评估方法。还提供了非常有用的新配体，用于GPR103基因和蛋白质的功能分析以及化合物评估。具有SEQ ID NO：1至4列出的序列的核酸或蛋白质提供非人灵长类动物或大鼠GPR103基因和基于基因和蛋白质的蛋白质和信息。基因和蛋白质可用于评价化合物。具有SEQ ID NO：5或6所列序列的核酸或蛋白质提供GPR103配体。

7. 发明申请

US20090311595A1 BATTERY CASE AND BATTERY USING THE SAME 审中-公开
标题翻译：电池盒和电池使用相同
公开(公告)号：US20090311595A1
公开(公告)日：2009-12-17
申请号：US12376248
申请日：2007-08-09
申请人： Katsuhiko Mori , Fumiharu Sakashita , Hideki Sano
发明人： Katsuhiko Mori , Fumiharu Sakashita , Hideki Sano
IPC分类号： H01M2/08
CPC分类号： H01M2/0275 , B32B15/015 , H01M2/0272 , H01M2/0287
摘要： An Fe—Ni diffusion layer (3) is formed on the surface of a steel plate (2) containing Fe in an amount of 98 percent by weight or more, and the Fe/Ni ratio is adjusted within the range of 0.1 to 2.5. The steel plate (2) is shaped into a battery case (1) having a predetermined shape with predetermined dimensions such that the Fe—Ni diffusion layer (3) serves as the inner surface of the battery case (1). When a battery is produced using the battery case (1), corrosion due to over-discharge is suppressed even when the amount of Ni used is small. Therefore, the produced battery is excellent in leakage resistance.
摘要翻译：在含有98重量％以上的Fe的钢板（2）的表面上形成Fe-Ni扩散层（3），将Fe / Ni比调节在0.1〜2.5的范围内。钢板（2）成形为具有预定尺寸的预定尺寸的电池壳体（1），使得Fe-Ni扩散层（3）用作电池壳体（1）的内表面。当使用电池壳体（1）制造电池时，即使当使用的Ni量小时，也会抑制由于过度放电引起的腐蚀。因此，所生产的电池具有优异的耐漏电性。

8. 发明申请

US20090176243A1 Novel monkey GPR103 and monkey QRFP and method of evaluating compound by using GPR103 失效
标题翻译：新型猴GPR103和猴QRFP以及使用GPR103评价化合物的方法
公开(公告)号：US20090176243A1
公开(公告)日：2009-07-09
申请号：US12215324
申请日：2008-06-26
申请人： Hideki Sano , Hisashi Iwaasa , Satoshi Mashiko
发明人： Hideki Sano , Hisashi Iwaasa , Satoshi Mashiko
IPC分类号： G01N33/53 , C12Q1/02 , C12N15/11
CPC分类号： C07K14/705 , G01N33/6893 , G01N33/6896 , G01N2333/726
摘要： There are provided non-human primate and rat GPR103 genes and proteins and a compound evaluation method employing the genes or proteins. There are also provided highly useful novel ligands for functional analysis of the GPR103 genes and proteins and for the compound evaluation. The nucleic acids or proteins having the sequences listed as SEQ ID NOS: 1 to 4 provide non-human primate or rat GPR103 genes and proteins and information based on the genes and proteins. The genes and proteins can be used for evaluation of compounds. The nucleic acids or proteins having the sequence listed as SEQ ID NO: 5 or 6 provide a GPR103 ligand.
摘要翻译：提供了非人灵长类动物和大鼠GPR103基因和蛋白质，以及使用基因或蛋白质的化合物评估方法。还提供了非常有用的新配体，用于GPR103基因和蛋白质的功能分析以及化合物评估。具有SEQ ID NO：1至4列出的序列的核酸或蛋白质提供非人灵长类动物或大鼠GPR103基因和基于基因和蛋白质的蛋白质和信息。基因和蛋白质可用于评价化合物。具有SEQ ID NO：5或6所列序列的核酸或蛋白质提供GPR103配体。

9. 发明授权

US07186681B2 Methods of modulating cell migration using galectin-3 失效
标题翻译：使用半乳凝素-3调节细胞迁移的方法
公开(公告)号：US07186681B2
公开(公告)日：2007-03-06
申请号：US09805449
申请日：2001-03-13
申请人： Fu-Tong Liu , Hideki Sano , Daniel K. Hsu
发明人： Fu-Tong Liu , Hideki Sano , Daniel K. Hsu
IPC分类号： A01N37/18 , A61K38/00 , A61K39/395
CPC分类号： G01N33/5094 , A61K38/1709 , A61K45/06 , A61K2039/505 , A61L26/0028 , A61L26/0066 , A61L27/22 , A61L27/227 , A61L27/54 , A61L2300/252 , A61L2300/404 , A61L2300/41 , A61L2300/416 , A61L2300/802 , C07K16/18 , G01N33/5047
摘要： The present invention relates to methods of modulating cell migration, particularly, monocyte, neutrophil or macrophage migration, using galectin-3, galectin-3 binding polypeptide, or galectin-3 receptor binding polypeptide. Specifically provided are methods for increasing cell migration to sites of inflammation, infection or a tumor. Also provided are methods for identifying agents that modulate galectin-3 mediated migration, compositions containing galectin-3 or a functional subsequence thereof, and microfabricated devices that deliver galectin-3 or functional galectin-3 subsequences.
摘要翻译：本发明涉及使用半乳凝素-3，半乳凝素-3结合多肽或半乳凝素-3受体结合多肽调节细胞迁移，特别是单核细胞，中性粒细胞或巨噬细胞迁移的方法。具体提供的是用于增加细胞迁移到炎症，感染或肿瘤部位的方法。还提供了用于鉴定调节半乳凝素-3介导的迁移的试剂的方法，含有半乳凝素-3或其功能性亚序列的组合物，以及递送半乳凝素-3或功能性半乳凝素-3子序列的微制剂。

10. 发明申请

US20070037219A1 Rhesus monkey bombesin receptor subtype-3 (brs-3), nucleotides encoding same, and uses thereof 审中-公开
标题翻译：恒河猴铃蟾肽受体亚型-3（brs-3），编码其的核苷酸及其用途
公开(公告)号：US20070037219A1
公开(公告)日：2007-02-15
申请号：US10553812
申请日：2004-04-14
申请人： Carina Tan , Andrew Howard , Hideki Sano
发明人： Carina Tan , Andrew Howard , Hideki Sano
IPC分类号： G01N33/567 , C07H21/04 , C12P21/06 , C12N5/06 , C07K14/705
CPC分类号： C07K14/70571 , C07K14/723 , G01N2333/70571
摘要： A rhesus monkey bombesin receptor subtype-3 has been isolated, cloned and sequenced. This receptor is characteristic of the G-protein family of receptors. Isolated rhesus monkey bombesin receptor subtype-3 may be used to screen and identify novel bombesin receptor modulators that may contribute to the regulation of endocrine processes, metabolism, or the cell cycle. Such compounds may be used in the treatment of conditions that result from deregulated expression of bombesin receptor subtype-3.
摘要翻译：已经分离，克隆和测序了恒河猴铃蟾肽受体亚型3。该受体是G-蛋白家族受体的特征。分离的恒河猴铃蟾肽受体亚型-3可用于筛选和鉴定可能有助于调节内分泌过程，代谢或细胞周期的新型bombesin受体调节剂。这些化合物可用于治疗由bombesin受体亚型-3的失调表达引起的病症。

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