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    • 3. 发明授权
    • Inhibiting lipoxygenase with pyrazolone derivatives
    • 用吡唑啉酮衍生物抑制脂氧合酶
    • US4670460A
    • 1987-06-02
    • US808582
    • 1985-12-13
    • Mithat MardinFriedel SeuterElisabeth PerzbornKlaus SchlossmannDieter MayerVolker Fiedler
    • Mithat MardinFriedel SeuterElisabeth PerzbornKlaus SchlossmannDieter MayerVolker Fiedler
    • A61K31/415
    • A61K31/415
    • A method of inhibiting lipoxygenase in a patient, for the prophylaxis and/or treatment of ischaemias and disorders in cardiac rhythm, inflammations of the skin and the eye, and of rheumatic, allergic and asthmatic diseases, oedemas, pulmonary embolisms, pulmonary hypertension, shock lung, oxygen intoxications and ulcerations which comprises administering to such patient an effective amount of a compound of the formula ##STR1## wherein R represents an aryl or heteroaryl radical which has 6 to 12 C atoms and optionally contains 1 to 3 identical or different substituents from the group comprising halogen, trifluoromethyl, alkyl, alkenyl, alkoxy, alkylamino, cyano, trifluoromethoxy, nitro, hydroxyl, SO.sub.n -alkyl (n=0 to 2) or SO.sub.n -trifluoromethyl (n=0 to 2), alkyl, alkenyl and alkoxy in each case being understood as meaning radicals with 1 to 4 C atoms,R.sup.1 represents hydrogen or a hydrocarbon radical which has 1 to 18 C atoms and optionally contains a hydroxyl, ether, ester or carboxyl group and optionally 1 to 3 halogen atoms,R.sup.2 has the meaning of R.sup.1 or represents radical ##STR2## R.sup.3 represents hydrogen or an acyl or sulphonyl radical with in each case 1 to 15 C atoms andX represents one of the groups --O--CH.sub.2 --CH.sub.2 --, --S--CH.sub.2 --CH.sub.2 --, --CH.sub.2 --CH.sub.2 --CH.sub.2 --, --CH.sub.2 --CH.sub.2 --, --CH.sub.2 or ##STR3## the oxygen or sulphur atom being bonded to the radical R, and with the provisio that X does not represent --O--CH.sub.2 --CH.sub.2 -- if R=.beta.-naphthyl, R.sup.1 =CH.sub.3 and R.sup.2 =R.sup.3 =H.
    • 一种在患者体内抑制脂氧合酶的方法,用于预防和/或治疗心脏节律,皮肤和眼睛炎症以及风湿性,过敏性和哮喘性疾病,oedemas,肺栓塞,肺动脉高压,休克 肺,氧中毒和溃疡,其包括向此类患者施用有效量的式(I)化合物,其中R表示具有6至12个C原子并且任选地含有1至3个相同或相同或相同的1至3个的芳基或杂芳基, 硝基,羟基,SO1-烷基(n = 0至2)或SO 3 - 三氟甲基(n = 0至2)的不同取代基,烷基,环烷基, 烯基和烷氧基在每种情况下被理解为含有1至4个C原子的基团,R 1表示氢或具有1至18个C原子并且任选地含有羟基,醚,酯或羧基的烃基 p和任选的1至3个卤素原子,R 2具有R 1的含义或表示基团R 3表示氢或酰基或磺酰基,在每种情况下为1至15个C原子,X表示基团-O-CH 2 -CH 2 - , - CH 2 -CH 2 - , - CH 2 -CH 2 - , - CH 2 -CH 2 - , - CH 2或者 - 或者与基团R键合的氧原子或硫原子, 如果R =β-萘基,R1 = CH3,R2 = R3 = H,则不表示-O-CH2-CH2-。
    • 8. 发明授权
    • Coupling device for coupling a frictional damper to a machine frame of a washing machine
    • 用于将摩擦阻尼器耦合到洗衣机的机架的联接装置
    • US06574997B1
    • 2003-06-10
    • US09959772
    • 2002-01-28
    • Dieter MayerHelge Siegner
    • Dieter MayerHelge Siegner
    • D06F3722
    • F16F7/08D06F37/20F16F2230/0047
    • The invention relates to a coupling device (19) for coupling a frictional damper with a middle longitudinal axis (21), which is coupled to an oscillatory washing unit with a drum axis, to a machine frame of a washing machine with a spin gear. The coupling device has a first bending axis, which runs vertically to the central longitudinal axis (21) and parallel to the drum axis, a second bending axis (33) which runs vertically to the central longitudinal axis (21) and to the first bending axis and intersects both at one point, a first connecting element for connecting the coupling device (19) to the frictional damper, a second connecting element for connecting the coupling device (19) to the machine frame and a spring element (24) that is located between the first connecting element and the second connecting element and is connected to both, the flexural strength of the coupling device (19) about the second bending axis (33) being greater than the flexural strength about the first bending axis.
    • 本发明涉及一种用于将摩擦阻尼器与中心纵向轴线(21)联接的联接装置(19),所述中间纵向轴线(21)与具有鼓轴线的振荡洗涤单元联接到具有旋转齿轮的洗衣机的机架。 联接装置具有第一弯曲轴线,其垂直于中心纵向轴线(21)延伸并且平行于鼓轴线;第二弯曲轴线(33),其垂直于中心纵向轴线(21)延伸并且与第一弯曲 轴线并且在一个点处相交,用于将联接装置(19)连接到摩擦阻尼器的第一连接元件,用于将联接装置(19)连接到机架上的第二连接元件和弹簧元件(24),弹簧元件 位于第一连接元件和第二连接元件之间并连接到两者上,耦合装置(19)围绕第二弯曲轴线(33)的弯曲强度大于围绕第一弯曲轴线的弯曲强度。