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1. 发明授权

US5027753A Intake system of multi-cylinder internal combustion engine 失效
标题翻译：多缸内燃机进气系统
公开(公告)号：US5027753A
公开(公告)日：1991-07-02
申请号：US491334
申请日：1990-03-09
申请人： Minoru Hamazaki , Toshihiro Oikawa , Yoshifusa Kanazawa
发明人： Minoru Hamazaki , Toshihiro Oikawa , Yoshifusa Kanazawa
IPC分类号： F02B27/02 , F02B75/22 , F02D13/02
CPC分类号： F02D13/0211 , F02B27/021 , F02B27/0252 , F02D13/0261 , F02B2275/18 , F02B75/22 , Y02T10/146 , Y02T10/18
摘要： An intake system of a multi-cylinder interval combustion engine including a common inlet duct, first and second resonating ducts branched from the downstream end of the inlet duct, first and second resonating chambers leading from the first and second resonating ducts, respectively, a plurality of first intake ducts for connecting the first resonating chamber to a first group of cylinders, respectively, having ignition timings set not to come adjacent to each other, respectively, a plurality of second intake ducts for connecting the second resonating chamber to a second group of cylinders, respectively, having ignition timings set not to come adjacent to each other, a common intake chamber capable of communicating with both the resonating chambers through communication ports which can be closed by valves, and an actuator for opening and closing the valves at least in response to the engine revolutions. A valve operating system is provided to control at least the closure timing of the intake valves at least in response to the engine revolutions.

2. 发明授权

US08669093B2 Biocatalyst for production of D-lactic acid 有权
标题翻译：用于生产D-乳酸的生物催化剂
公开(公告)号：US08669093B2
公开(公告)日：2014-03-11
申请号：US10573813
申请日：2004-09-17
申请人： Mitsufumi Wade , Toshihiro Oikawa , Daisuke Mochizuki , Junko Tokuda , Miyuki Kawashima , Tadashi Araki , Reiko Abe , Hitoki Miyake , Hitoshi Takahashi , Hideki Sawai , Takashi Mimitsuka , Takashi Morishige , Yosuke Higashi
发明人： Mitsufumi Wade , Toshihiro Oikawa , Daisuke Mochizuki , Junko Tokuda , Miyuki Kawashima , Tadashi Araki , Reiko Abe , Hitoki Miyake , Hitoshi Takahashi , Hideki Sawai , Takashi Mimitsuka , Takashi Morishige , Yosuke Higashi
IPC分类号： C12N1/21 , C12P7/56 , C12N1/26
CPC分类号： C12P7/56
摘要： A method for producing D-lactic acid in high yield, and to provide a method for producing D-lactic acid with high selectivity, in which optical purity is high and a by-product organic acid is small. In one aspect, a microorganism, wherein activity of pyruvate formate-lyase (pfl) is inactivated or decreased, and further activity of Escherichia coli-derived NADH-dependent D-lactate dehydrogenase (ldhA) is enhanced, is cultured to efficiently produce D-lactic acid. With regard to a method for enhancing ldhA activity, by linking, on a genome, a gene encoding ldhA with a promoter of a gene which controls expression of a protein involved in a glycolytic pathway, a nucleic acid biosynthesis pathway or an amino acid biosynthesis pathway, suitable results are obtained compared to the method for enhancing expression of the gene using an expression vector. A microorganism in which a dld gene is substantially inactivated or decreased is cultured to produce high quality D-lactic acid with reduced concentration of pyruvic acid.
摘要翻译：提供高产率D-乳酸的制造方法，提供高纯度的高纯度D-副乳酸和副产物有机酸的生产方法。在一个方面，培养其中丙酮酸甲酸裂合酶（pfl）的活性失活或降低，并且进一步增强大肠杆菌来源的NADH依赖性D-乳酸脱氢酶（ldhA）的活性的微生物，以有效地产生D- 乳酸。关于增强ldhA活性的方法，通过在基因组上连接编码ldhA的基因与控制糖酵解途径参与蛋白质的表达的基因的启动子，核酸生物合成途径或氨基酸生物合成途径与使用表达载体增强基因表达的方法相比，获得了合适的结果。培养其中dld基因基本上失活或减少的微生物被培养以产生具有降低的丙酮酸浓度的高质量D-乳酸。

3. 发明申请

US20050054042A1 Novel gluconate dehydratase 有权
标题翻译：新型葡萄糖酸脱水酶
公开(公告)号：US20050054042A1
公开(公告)日：2005-03-10
申请号：US10885874
申请日：2004-07-08
申请人： Hitoki Miyake , Toshifumi Yamaki , Toshihiro Oikawa , Takeshi Nakamura , Hiroki Ishibashi , Yasushi Fukuiri , Atsushi Sakuma , Hironori Komatsu , Tomoyuki Ando , Kazuhiko Togashi , Hideki Umetani
发明人： Hitoki Miyake , Toshifumi Yamaki , Toshihiro Oikawa , Takeshi Nakamura , Hiroki Ishibashi , Yasushi Fukuiri , Atsushi Sakuma , Hironori Komatsu , Tomoyuki Ando , Kazuhiko Togashi , Hideki Umetani
IPC分类号： C12N9/04 , C12N9/88 , C12N15/55 , C12P7/58 , C12N9/78 , C07H21/04 , C12N15/74 , C12P7/06
CPC分类号： C12N9/88 , C12P7/58 , C12Y402/01039
摘要： A novel gluconate dehydratase derived from Achromobacter xylosoxidans and a gene encoding the gluconate dehydratase are provided. By reacting the gluconate dehydratase or a transformed cell containing the gene with an aldonic acid, the corresponding 2-keto-3-deoxyaldonic acid can be efficiently produced.
摘要翻译：本发明提供了一种衍生自木糖无色杆菌的新型葡萄糖酸脱水酶和编码葡萄糖酸脱水酶的基因。通过使葡糖酸脱水酶或含有该基因的转化细胞与醛糖酸反应，可以有效地制备相应的2-酮-3-脱氧醛酸。

4. 发明授权

US4955121A Method for producing a rocker arm for use in an internal combustion engine 失效
标题翻译：一种用于内燃机的摇臂的制造方法
公开(公告)号：US4955121A
公开(公告)日：1990-09-11
申请号：US71652
申请日：1987-07-09
申请人： Masakazu Sato , Seiichi Koike , Toshihiro Oikawa , Keisuke Ban
发明人： Masakazu Sato , Seiichi Koike , Toshihiro Oikawa , Keisuke Ban
IPC分类号： B22D27/11
CPC分类号： B21K1/205 , B22D27/11 , Y10T29/49295 , Y10T29/49989
摘要： A method for casting a rocker arm made of light alloy for use in an overhead cam shaft type valve operating mechanism of an internal combustion engine, which rocker arm includes a thick-walled bearing section to be fitted on a rocker arm shaft and is integrally provided with a wear-resistive piece having a protrusion on its rear surface and adapted to abut a cam. After molten metal has been injected under pressure into a metallic mold for the rocker arm, a secondary pressurizing force directed in the direction of an imaginary center axis of a rocker arm shaft is exerted by means of a pressurizing rod. In the metallic mold for the rocker arm, a sprue is provided close to the position where the wear-resistive piece is disposed with respect to the position where the bearing section is formed, and the direction of the sprue is directed towards the position where the wear-resistive place is disposed.
摘要翻译：一种用于铸造用于内燃机的顶部凸轮轴型阀操作机构的由轻合金制成的摇臂的方法，所述摇臂包括将被安装在摇臂轴上的厚壁轴承部分并且一体地设置具有在其后表面上具有凸起并且适于邻接凸轮的耐磨件。在压力下将熔融金属注入到用于摇臂的金属模具中之后，通过加压杆来施加沿摇臂轴的假想中心轴方向的二次加压力。在用于摇臂的金属模具中，相对于形成有轴承部的位置，在耐磨件设置的位置附近设有浇道，并且浇道的方向被引导到设置耐磨地点。

5. 发明授权

US4748946A SOHC type internal combustion engine 失效
标题翻译： SOHC型内燃机
公开(公告)号：US4748946A
公开(公告)日：1988-06-07
申请号：US70987
申请日：1987-07-08
申请人： Noriaki Fujii , Takeshi Iwata , Toshihiro Oikawa
发明人： Noriaki Fujii , Takeshi Iwata , Toshihiro Oikawa
IPC分类号： F01L1/04 , B23K26/06 , F01L1/053 , F01L1/12 , F01L1/18 , F01L1/26 , F02B1/04 , F02F1/24 , F02F1/38 , F02F1/42 , F02P13/00 , F02P15/00
CPC分类号： F02F1/4214 , F01L1/053 , F01L1/26 , F02B1/04 , F02B2275/20 , F02F2001/245
摘要： An SOHC type internal combustion engine having a cam shaft for opening and closing intake and exhaust valves via rocker arms, the cam shaft being held between a cam shaft receiving wall of a cylinder head and a cam shaft holder which is secured to the cam shaft receiving wall, wherein a hole for allowing insertion of an ignition plug into a plug mounting hole is formed in the cam shaft receiving wall and opens to the surface of the wall against which a cam shaft holder abuts, and a hole for guiding a high power cord for an ignition plug is formed between the mutually abutting surfaces of the cam shaft receiving wall and the cam shaft holder.
摘要翻译：一种SOHC型内燃机，其具有用于通过摇臂打开和关闭进气和排气阀的凸轮轴，所述凸轮轴保持在气缸盖的凸轮轴接收壁和凸轮轴保持器之间，所述凸轮轴保持器固定到所述凸轮轴接收壁，其中，用于允许将火花塞插入插头安装孔的孔形成在凸轮轴接收壁中，并且通向凸轮轴保持器邻接的壁的表面，以及用于引导高功率线的孔因为在凸轮轴接收壁和凸轮轴保持器的相互抵接的表面之间形成火花塞。

6. 发明授权

US4637358A Spark plug cap apparatus 失效
标题翻译：火花塞帽装置
公开(公告)号：US4637358A
公开(公告)日：1987-01-20
申请号：US781247
申请日：1985-09-27
申请人： Yoshiki Yano , Toshihiro Oikawa
发明人： Yoshiki Yano , Toshihiro Oikawa
IPC分类号： F02B1/04 , F02F1/24 , H01T13/04 , F02P1/00
CPC分类号： F02F1/242 , H01T13/04 , F02B1/04
摘要： A spark plug cap apparatus for an internal combustion engine having relatively deep and generally vertical spark plug receiving bores. The upper end of the bore is provided with an annular protrusion. A resilient head cover has a bent flange for extending over and sealably engaging the annular protrusion. The head cover has a downwardly extending seal lip for engaging the inside of the bore. A pipe is molded to the head cover and extends downwardly to engage the top of the spark plug. The spark wire extends through the head cover and pipe. A vent hole is provided in the head cover.
摘要翻译：一种用于内燃机的火花塞盖设备，其具有相对较深且基本垂直的火花塞接收孔。孔的上端设置有环形突起。弹性头盖具有弯曲的凸缘，用于延伸并密封地接合环形突起。头盖具有用于接合孔内部的向下延伸的密封唇。管道被模制到头盖并向下延伸以接合火花塞的顶部。火花线延伸穿过头盖和管道。头盖上设有通气孔。

7. 发明申请

US20070015265A1 Novel gluconate dehydratase 有权
标题翻译：新型葡萄糖酸脱水酶
公开(公告)号：US20070015265A1
公开(公告)日：2007-01-18
申请号：US11523691
申请日：2006-09-20
申请人： Hitoki Miyake , Toshifumi Yamaki , Toshihiro Oikawa , Takeshi Nakamura , Hiroki Ishibashi , Yasushi Fukuiri , Atsushi Sakuma , Hironori Komatsu , Tomoyuki Ando , Kazuhiko Togashi , Hideki Umetani
发明人： Hitoki Miyake , Toshifumi Yamaki , Toshihiro Oikawa , Takeshi Nakamura , Hiroki Ishibashi , Yasushi Fukuiri , Atsushi Sakuma , Hironori Komatsu , Tomoyuki Ando , Kazuhiko Togashi , Hideki Umetani
IPC分类号： C12P7/58 , C07H21/04 , C12P21/06 , C12N9/04 , C12N15/74 , C12N1/21
CPC分类号： C12N9/88 , C12P7/58 , C12Y402/01039
摘要： A novel gluconate dehydratase derived from Achromobacter xylosoxidans and a gene encoding the gluconate dehydratase are provided. By reacting the gluconate dehydratase or a transformed cell containing the gene with an aldonic acid, the corresponding 2-keto-3-deoxyaldonic acid can be efficiently produced.
摘要翻译：本发明提供了一种衍生自木糖无色杆菌的新型葡萄糖酸脱水酶和编码葡萄糖酸脱水酶的基因。通过使葡糖酸脱水酶或含有该基因的转化细胞与醛糖酸反应，可以有效地制备相应的2-酮-3-脱氧醛酸。

8. 发明授权

US6125805A Valve operating system in internal combustion engine 有权
标题翻译：内燃机阀门操作系统
公开(公告)号：US6125805A
公开(公告)日：2000-10-03
申请号：US420409
申请日：1999-10-19
申请人： Toshiyuki Sato , Toshihiro Oikawa , Yutaka Otobe
发明人： Toshiyuki Sato , Toshihiro Oikawa , Yutaka Otobe
IPC分类号： F01L1/26 , F01L13/00
CPC分类号： F01L1/267 , F01L2105/02
摘要： A valve operating system in an internal combustion engine includes a cam shaft provided with a plurality of valve operating cams, a plurality of rocker arms positioned adjacent one another, an associative operation switch capable of being switched between a state in which it permits the rocker arms adjacent each other to be operated associatively with each other, and a state in which it releases the associative operation. An urging means for urging the free rocker arm of the plurality of rocker arms toward the valve operating cam corresponding to the free rocker arm, which becomes free relative to an engine valve, when the associative operation switch is brought into the associative operation releasing state. The free rocker arm is provided with first and second support walls spaced apart and opposed to each other, and a roller is provided in rolling contact with a valve operating cam corresponding to the free rocker arm, and is rollably supported on a support shaft mounted to extend between the support walls through a bearing. In such valve operating system, one of the support walls included in the free rocker arm is integrally provided with a receiving portion which contacts with the urging means. Therefore, the structure of the free rocker arm can be simplified in such a manner that the receiving portion is positioned to the side of the roller. In addition, an increase in size of the free rocker arm can be avoided, and the inertial weight is reduced. Thus, it is possible to conveniently accommodate the high-speed rotation of the internal combustion engine.
摘要翻译：一种内燃机中的气门操作系统，具有设置有多个气门操作凸轮的凸轮轴，相邻的多个摇臂，能够切换的状态，该状态允许摇臂彼此相邻地彼此相关地操作，以及释放关联操作的状态。一种推动装置，用于当关联操作开关进入关联操作释放状态时，将多个摇臂的自由摇臂朝向相对于发动机气门变空的自由摇臂相应的气门操作凸轮推动。自由摇臂设置有彼此间隔开并彼此相对的第一和第二支撑壁，并且设置有与对应于自由摇臂的气门操作凸轮滚动接触的辊，并且可滚动地支撑在安装到通过轴承在支撑壁之间延伸。在这种阀操作系统中，包括在自由摇臂中的一个支撑壁一体地设置有与推动装置接触的接收部分。因此，可以简化自由摇臂的结构，使得接收部分位于辊的侧面。此外，可以避免自由摇臂的尺寸增加，并且惯性重量减小。因此，可以方便地适应内燃机的高速旋转。

9. 发明授权

US6060290A Esterase and methods for the production of optically active chroman compounds 失效
标题翻译：酯酶和用于制备光学活性色满化合物的方法
公开(公告)号：US6060290A
公开(公告)日：2000-05-09
申请号：US118275
申请日：1998-07-17
申请人： Toshihiro Oikawa , Nobuhiro Fukuhara , Yasuko Matsuba
发明人： Toshihiro Oikawa , Nobuhiro Fukuhara , Yasuko Matsuba
IPC分类号： C12N9/18 , C12N15/55 , C12P17/06 , C12P41/00
CPC分类号： C12N9/18 , C12P17/06 , C12P41/005
摘要： Optically active chroman-3-acetic acids and optically active chroman-3-acetic acid esters can be obtained by treating a mixture of (3R)- and (3S)-chroman-3-acetic esters of formula (I) ##STR1## [wherein R.sub.1 is a straight or branched alkyl group having 1-5 carbon atoms and R.sub.2 is a hydrogen atom or substituted or unsubstituted amino group]is treated with an esterase which has an optically selective hydrolyzing activity or microorganisms which carry said hydrolase, or a preparation therefrom. A novel esterase derived from bacteria of genus Pseudonocardia can also be used as said esterase.
摘要翻译：通过处理式（I）的（3R） - （3S） - 苯并二氢吡喃-3-乙酸酯的混合物[其中R 1是（R 3））和（3S） - 苯并二氢吡喃-3-乙酸酯的混合物可以获得光学活性色满-3-乙酸和光学活性色满-3-乙酸酯具有1-5个碳原子的直链或支链烷基，R2是氢原子或取代或未取代的氨基]用具有光学选择性水解活性的酯酶或携带所述水解酶的微生物或其制备物进行处理。也可以使用衍生自假诺卡氏菌属细菌的新型酯酶作为所述酯酶。

10. 发明授权

US5228423A Dual-fuel engine 失效
标题翻译：双燃料发动机
公开(公告)号：US5228423A
公开(公告)日：1993-07-20
申请号：US960162
申请日：1992-10-13
申请人： Toshihiro Oikawa , Shunichi Tsuzuki , Yuji Yamamoto
发明人： Toshihiro Oikawa , Shunichi Tsuzuki , Yuji Yamamoto
IPC分类号： F01L1/26 , F02B69/00 , F02D13/02 , F02D19/06 , F02M21/02
CPC分类号： F02D13/0226 , F01L1/267 , F02B69/00 , F02D13/0257 , F02D19/0615 , F02D19/0647 , F02D19/0692 , F02M35/10045 , F02M35/1085 , Y02T10/18 , Y02T10/36
摘要： In a dual-fuel internal combustion engine which can selectively use gaseous fuel such as CNG or liquid fuel such as gasoline, a pair of intake passages are independently connected to a combustion chamber of the engine, and a gaseous fuel supply device and a liquid fuel supply device are provided in the corresponding intake passages so that the liquid and gaseous fuels may not mix with each other when the fuel for the engine is switched over one from the other as they are introduced into the combustion chamber through different intake passages. Further, by switching the operating mode of the intake valve when changing the fuel, the configuration of the intake passage can be optimized for each fuel, and the timing and the lift of the intake valves may also be optimized for each fuel without complicating the control structure of the overall system. The present invention can improve the torque output and the emission property of the dual-fuel engine.
摘要翻译：在能够选择性地使用气体燃料如CNG或液体燃料如汽油的双燃料内燃机中，一对进气通道独立地连接到发动机的燃烧室，气体燃料供应装置和液体燃料供给装置设置在相应的进气通道中，使得当用于发动机的燃料在通过不同的进气通道被引入燃烧室中时，将发动机的燃料从另一个切换而使液体和气体燃料彼此不混合。此外，通过在改变燃料时切换进气门的操作模式，可以对每个燃料优化进气通道的构造，并且还可以针对每种燃料优化进气门的正时和升程，而不会使控制复杂化整体系统的结构。本发明可以提高双燃料发动机的扭矩输出和排放性能。

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