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    • 4. 发明授权
    • Process for producing a microcapsule containing a liquid active material
    • 制备含有液体活性物质的微胶囊的方法
    • US4690786A
    • 1987-09-01
    • US832602
    • 1986-02-24
    • Yasuo NinomiyaChiaki KomamuraYoshikazu Musa
    • Yasuo NinomiyaChiaki KomamuraYoshikazu Musa
    • A01N25/28A61K9/58B01J13/04B01J13/12A61K9/52B01J13/02
    • A01N25/28B01J13/125Y10S514/963Y10T428/2985Y10T428/2987
    • A process for producing a microcapsule containing a liquid active material is described, comprising the steps of:(1) dissolving in an organic solvent a polymer, esp. a polysulfone and an active material which has a limited solubility of about 0.01 to about 2 parts by weight in 100 parts by weight of said polymer and which is liquid at room temperature, the amount of said liquid active material added being more than the limited solubility and being about 2 to about 250 parts by weight per 100 parts by weight of the polymer and said organic solvent being capable of dissolving the respective components and being more volatile than said active material;(2) atomizing the resulting solution through a nozzle into a gaseous atmosphere to form a mist of tiny liquid droplets; and(3) removing the solvent from the droplets by evaporation so as to provide a microcapsule having the liquid active material confined by the wall of said microcapsule made of the polymer.
    • 描述了含有液体活性物质的微胶囊的制造方法,包括以下步骤:(1)在有机溶剂中溶解聚合物, 聚砜和活性物质,其在100重量份所述聚合物中具有约0.01至约2重量份的有限溶解度,并且在室温下为液体,所加入的所述液体活性物质的量大于受限的溶解度 并且每100重量份聚合物为约2至约250重量份,并且所述有机溶剂能够溶解各成分并且比所述活性物质更易挥发; (2)将得到的溶液通过喷嘴雾化成气态,形成微小的液滴雾; 和(3)通过蒸发从液滴中除去溶剂,从而提供具有由聚合物制成的所述微胶囊的壁所限定的液体活性物质的微胶囊。