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    • 9. 发明授权
    • Orthovoltage radiotherapy
    • 电磁放电
    • US07978818B2
    • 2011-07-12
    • US12493136
    • 2009-06-26
    • Michael GertnerSteven D. HansenErik ChellMark ArnoldussenMatt Herron
    • Michael GertnerSteven D. HansenErik ChellMark ArnoldussenMatt Herron
    • A61N5/10G21K5/08A61B6/08
    • A61N5/1067A61B6/506A61B6/508A61N5/10A61N5/1001A61N5/1017A61N5/1045A61N5/1048A61N5/1049A61N5/1064A61N5/1065A61N5/1077A61N5/1084A61N2005/1019A61N2005/1022A61N2005/105A61N2005/1051A61N2005/1059A61N2005/1091A61N2005/1097
    • A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, the target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, the target tissues inside the global coordinate system lead to direction of an automated positioning system that is directed based on the target tissues within the coordinate system. In some embodiments, a treatment plan is utilised in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial marker is used to identify the location of the target tissues. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.
    • 描述了放射外科系统,其被配置为将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中,治疗炎症性眼部疾病,特别是黄斑变性。 在一些实施方案中,身体的其它病症或组织用辐射剂量治疗。 在一些实施例中,目标组织基于眼睛成像被放置在全局坐标系中。 在一些实施例中,全局坐标系统内的目标组织导致基于坐标系统内的目标组织定向的自动定位系统的方向。 在一些实施例中,使用治疗计划,其中针对要治疗的特定疾病和/或要避免的结构确定束能量和治疗时间的方向和持续时间。 在一些实施方案中,使用基准标记来鉴定靶组织的位置。 在一些实施例中,描述了放射外科手术与其他治疗组合使用的放射治疗疗法,并且可以在其它治疗之前,之前或之后进行递送。
    • 10. 发明申请
    • OCULAR RADIOSURGERY
    • 眼科放射科医师
    • US20100172473A1
    • 2010-07-08
    • US12725406
    • 2010-03-16
    • Michael GertnerErik ChellSteven D. HansenMark ArnoldussenMatt HerronKuang-Hung Pan
    • Michael GertnerErik ChellSteven D. HansenMark ArnoldussenMatt HerronKuang-Hung Pan
    • A61N5/10
    • A61N5/1049A61B6/506A61B2017/306A61F9/009A61N5/1017A61N5/103A61N2005/105A61N2005/1056A61N2005/1091
    • A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system. In some embodiments, the position of the ocular structure is tracked and related to the status of the radiosurgery system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, the structure is an eye and the eye is tracked by the system. In some embodiments, the eye is held in place and in some embodiments, the eye is fixed by the patient. In some embodiments, a fiducial is placed on the eye to aid in positioning. In some embodiments, a reflection off the eye is used to aid in positioning. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.
    • 描述了放射外科系统,其被配置为将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中,治疗炎症性眼部疾病,特别是黄斑变性。 在一些实施例中,将眼部结构置于基于眼睛成像的全局坐标系中。 在一些实施例中,全局坐标系内的目镜结构导致基于坐标系内的眼睛结构而被引导的自动定位系统的方向。 在一些实施例中,跟踪眼结构的位置并且与放射外科手术系统的状态相关。 在一些实施例中,使用治疗计划,其中针对要治疗的特定疾病和/或要避免的结构确定束能量和治疗时间的方向和持续时间。 在一些实施例中,结构是眼睛,并且眼睛被系统跟踪。 在一些实施例中,眼睛被保持就位,并且在一些实施例中,眼睛被患者固定。 在一些实施例中,将基准置于眼睛上以帮助定位。 在一些实施例中,使用眼睛的反射来帮助定位。 在一些实施例中,描述了放射外科手术与其他治疗组合使用的放射治疗疗法,并且可以在其它治疗之前,之前或之后进行递送。