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1. 发明专利

HK1156491A1 神經的能量調節未知
公开(公告)号：HK1156491A1
公开(公告)日：2012-06-15
申请号：HK11110882
申请日：2011-10-13
申请人： KONA MEDICAL INC , MICHAEL GERTNER
发明人： GERTNER MICHAEL
IPC分类号： A61B20060101

2. 发明专利

MY160595A ENERGETIC MODULATION OF NERVES 未知
公开(公告)号：MY160595A
公开(公告)日：2017-03-15
申请号：MYPI2012001623
申请日：2010-10-11
申请人： KONA MEDICAL INC , MICHAEL GERTNER
发明人： GERTNER MICHAEL
IPC分类号： A61B8/00 , A61B5/00 , A61B6/00 , A61B8/06 , A61N5/00 , A61N5/067 , A61N7/00
摘要： IN SOME EXAMPLES, NERVES SURROUNDING ARTERIES OR LEADING TO ORGANS ARE TARGETED WITH ENERGY SOURCES TO CORRECT OR MODULATE PHYSIOLOGIC PROCESSES. IN SOME EXAMPLES, DIFFERENT TYPES OF ENERGY SOURCES ARE UTILIZED SINGLY OR COMBINED WITH ONE ANOTHER. IN SOME EXAMPLES, BIOACTIVE AGENTS OR DEVICES ACTIVATED BY THE ENERGY SOURCES ARE DELIVERED TO THE REGION OF INTEREST AND THE ENERGY IS ENHANCED BY SUCH AGENTS OR THE AGENTS ARE ENHANCED BY THE ENERGY SOURCES.

3. 发明授权

US09358401B2 Intravascular catheter to deliver unfocused energy to nerves surrounding a blood vessel 有权
标题翻译：血管内导管向血管周围的神经输送未聚焦的能量
公开(公告)号：US09358401B2
公开(公告)日：2016-06-07
申请号：US13417194
申请日：2012-03-09
申请人： Michael Gertner
发明人： Michael Gertner
IPC分类号： A61B8/14 , A61N2/00 , A61B5/055 , A61B5/00 , A61B8/00 , A61B8/06 , A61B8/08 , A61N5/06 , A61N7/00 , A61N7/02 , A61B17/32 , A61B18/18 , A61N5/00 , A61B18/14 , A61N1/05 , A61B5/0225 , A61B6/03 , A61B19/00 , A61B18/00 , A61B6/00
CPC分类号： A61N2/006 , A61B5/0225 , A61B5/055 , A61B5/4035 , A61B5/4041 , A61B5/4047 , A61B5/4052 , A61B5/412 , A61B5/4528 , A61B5/4839 , A61B5/489 , A61B5/4893 , A61B6/03 , A61B6/032 , A61B6/037 , A61B6/506 , A61B8/00 , A61B8/06 , A61B8/08 , A61B8/4245 , A61B8/485 , A61B17/320068 , A61B18/14 , A61B18/18 , A61B90/37 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2090/374 , A61B2090/3762 , A61B2090/378 , A61N1/0551 , A61N5/00 , A61N5/0601 , A61N5/062 , A61N5/0622 , A61N7/00 , A61N7/02 , A61N2005/063 , A61N2007/0026 , A61N2007/003 , A61N2007/0078
摘要： In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources.
摘要翻译：在一些实例中，围绕动脉或通向器官的神经以能量来靶向以校正或调节生理过程。在一些示例中，不同类型的能量源单独使用或彼此组合使用。在一些实例中，由能量源激活的生物活性剂或装置被输送到感兴趣的区域，并且能量被这种试剂增强，或者这些试剂被能量源增强。

4. 发明授权

US08986211B2 Energetic modulation of nerves 有权
标题翻译：神经的能量调节
公开(公告)号：US08986211B2
公开(公告)日：2015-03-24
申请号：US13048844
申请日：2011-03-15
申请人： Michael Gertner , David Perozek , Arash Sabet , Jimin Zhang , Thomas Anderson
发明人： Michael Gertner , David Perozek , Arash Sabet , Jimin Zhang , Thomas Anderson
IPC分类号： A61B5/055 , A61B5/20 , A61B5/00 , A61B6/03 , A61B8/06 , A61N5/06 , A61N7/00 , A61N7/02 , A61B5/0225 , A61B5/026 , A61B6/00 , A61B8/08 , A61B19/00 , A61B18/00
CPC分类号： A61N7/00 , A61B5/0225 , A61B5/0263 , A61B5/055 , A61B5/201 , A61B5/412 , A61B5/4528 , A61B5/4839 , A61B5/489 , A61B5/4893 , A61B6/032 , A61B6/037 , A61B6/487 , A61B6/504 , A61B6/506 , A61B8/06 , A61B8/0841 , A61B8/0891 , A61B8/4245 , A61B8/485 , A61B8/488 , A61B90/37 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2090/374 , A61B2090/3762 , A61B2090/378 , A61N5/0601 , A61N5/062 , A61N5/0622 , A61N7/02 , A61N2005/063 , A61N2007/0026 , A61N2007/003 , A61N2007/0078
摘要： A method to deliver focused ultrasound energy from a position outside a skin of a patient to a nerve surrounding a blood vessel, includes placing the patient on a table in a substantially flat position, moving a transducer into a position inferior to ribs, superior to an iliac crest, and lateral to a spine of the patient, maintaining the transducer at the position relative to the patient, and delivering focused ultrasound energy through the skin of the patient without traversing bone, wherein the direction of the focused ultrasound is directed from a lower torso to an upper torso of the patient.
摘要翻译：将聚焦超声能量从患者皮肤外部的位置输送到血管周围的神经的方法，包括将患者放置在基本上平坦的位置的台上，将换能器移动到低于肋的位置，优于髂嵴和患者的脊柱侧面，将换能器保持在相对于患者的位置，并且将聚焦的超声波能量穿过患者的皮肤而不穿过骨骼，其中聚焦超声波的方向指向下方躯干到患者的上身。

5. 发明授权

US08457277B2 Orthovoltage radiosurgery 有权
标题翻译：矫正放射外科手术
公开(公告)号：US08457277B2
公开(公告)日：2013-06-04
申请号：US12755378
申请日：2010-04-06
申请人： Michael Gertner , Steven D. Hansen
发明人： Michael Gertner , Steven D. Hansen
IPC分类号： A61N5/10
CPC分类号： A61N5/1067 , A61B6/506 , A61B6/508 , A61N5/10 , A61N5/1001 , A61N5/1017 , A61N5/1045 , A61N5/1048 , A61N5/1049 , A61N5/1064 , A61N5/1065 , A61N5/1077 , A61N5/1084 , A61N2005/1019 , A61N2005/1022 , A61N2005/105 , A61N2005/1051 , A61N2005/1059 , A61N2005/1091 , A61N2005/1097
摘要： A radiosurgery system is configured to deliver a therapeutic dose of radiation to a target structure in a patient. The target tissues are placed in a global coordinate system based on ocular imaging. The target tissues inside the global coordinate system lead to direction of an automated positioning system that is directed based on the target tissues within the coordinate system. A treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. A fiducial marker is used to identify the location of the target tissues. The device automatically turns off with excessive movement outside of alignment along an axis of the eye. Radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.
摘要翻译：放射外科系统被配置为将治疗剂量的辐射递送到患者中的目标结构。将目标组织置于基于眼睛成像的全局坐标系中。全局坐标系内的目标组织导致基于坐标系内的目标组织定向的自动定位系统的方向。使用治疗计划，其中针对要治疗的特定疾病和/或要避免的结构确定束能量和治疗时间的方向和持续时间。使用基准标记来识别靶组织的位置。该装置沿着眼睛的轴线的对准外部的过度运动自动关闭。描述了放射外科手术与其他治疗组合使用的放射治疗疗法，并且可以在其他治疗之前，之前或之后进行递送。

6. 发明授权

US08343031B2 Obesity treatment systems 失效
标题翻译：肥胖治疗系统
公开(公告)号：US08343031B2
公开(公告)日：2013-01-01
申请号：US12099752
申请日：2008-04-08
申请人： Michael Gertner
发明人： Michael Gertner
IPC分类号： A61F2/00
CPC分类号： A61B17/0401 , A61B17/00234 , A61B17/0218 , A61B17/0469 , A61B17/0487 , A61B17/1114 , A61B17/29 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/1135 , A61F5/0073 , A61F5/0086
摘要： In some embodiments, an extragastric balloon is described in which the balloon is contoured to fit a portion of the stomach but not circumscribe the stomach. In some embodiments, the extragastric balloon comprises multiple material components. In some embodiments, the extragastric balloon comprises multiple inflateable compartments. In some embodiments, the extragastric balloon is filled with one or more of a gas, liquid, solid, or foams to create portions of the balloon with differing densities or buoyancies. In some embodiments, multiple anchors contact the stomach, each of which are inflateable with a fluid such as a liquid, gas, or gel. In some embodiments, a pressure sensor is described which is programmable from a place external to the patient and can be programmed to increase its sampling frequency when an ingestion event is detected.
摘要翻译：在一些实施例中，描述了一种胃外气囊，其中气囊被轮廓化以配合胃的一部分，但不包围胃。在一些实施例中，胃外包囊包括多个材料成分。在一些实施例中，胃外气囊包括多个可膨胀隔室。在一些实施例中，胃内气囊用气体，液体，固体或泡沫中的一种或多种填充，以产生具有不同密度或浮力的部分气囊。在一些实施例中，多个锚接触胃，每个锚定体可以用流体例如液体，气体或凝胶充气。在一些实施例中，描述了可以从患者外部的位置编程的压力传感器，并且当被检测到摄取事件时可被编程为增加其采样频率。

7. 发明申请

US20120271171A1 ENERGETIC MODULATION OF NERVES 有权
标题翻译：神经的能量调节
公开(公告)号：US20120271171A1
公开(公告)日：2012-10-25
申请号：US13535070
申请日：2012-06-27
申请人： Michael Gertner
发明人： Michael Gertner
IPC分类号： A61N7/00 , A61B8/14
CPC分类号： A61N2/006 , A61B5/0225 , A61B5/055 , A61B5/4035 , A61B5/4041 , A61B5/4047 , A61B5/4052 , A61B5/412 , A61B5/4528 , A61B5/4839 , A61B5/489 , A61B5/4893 , A61B6/03 , A61B6/032 , A61B6/037 , A61B6/506 , A61B8/00 , A61B8/06 , A61B8/08 , A61B8/4245 , A61B8/485 , A61B17/320068 , A61B18/14 , A61B18/18 , A61B90/37 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2090/374 , A61B2090/3762 , A61B2090/378 , A61N1/0551 , A61N5/00 , A61N5/0601 , A61N5/062 , A61N5/0622 , A61N7/00 , A61N7/02 , A61N2005/063 , A61N2007/0026 , A61N2007/003 , A61N2007/0078
摘要： A system to modulate an autonomic nerve in a patient utilizing transcutaneous ultrasound energy delivery includes a processor comprising an input for receiving information regarding energy and power to be delivered to a treatment region containing the nerve, and an output for outputting a signal, wherein the processor is configured to determine a position of a reference target from outside the patient to localize the nerve relative to the reference target, a therapeutic energy device comprising a transducer for delivering ultrasound energy from outside the patient, a controller to control an aiming of the transducer based at least in part on the signal from the processor, and an imaging system coupled to the processor or the therapeutic energy device.
摘要翻译：利用经皮超声能量递送来调节患者的自主神经的系统包括处理器，该处理器包括用于接收关于要传递到包含神经的治疗区域的能量和功率的信息的输入端和用于输出信号的输出端，其中处理器被配置为从患者外部确定参考目标的位置以相对于参考目标定位神经，包括用于从患者外部递送超声能量的换能器的治疗能量装置，用于控制基于传感器的瞄准的控制器至少部分地来自处理器的信号，以及耦合到处理器或治疗能量装置的成像系统。

8. 发明授权

US08295912B2 Method and system to inhibit a function of a nerve traveling with an artery 有权
标题翻译：抑制动脉神经功能的方法和系统
公开(公告)号：US08295912B2
公开(公告)日：2012-10-23
申请号：US12685655
申请日：2010-01-11
申请人： Michael Gertner
发明人： Michael Gertner
IPC分类号： A61N7/00
CPC分类号： A61N7/00 , A61B5/055 , A61B6/032 , A61B6/506 , A61B8/06 , A61B8/0833 , A61B8/0841 , A61B8/0891 , A61B8/483 , A61B8/488 , A61B18/1492 , A61B18/18 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2034/2051 , A61B2090/374 , A61B2090/378 , A61N7/02 , A61N2007/003 , A61N2007/0078
摘要： In some embodiments, sympathetic nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some embodiments, different types of energy sources are utilized singly or combined with one another. In some embodiments, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents.
摘要翻译：在一些实施方案中，围绕动脉或通向器官的交感神经以能量来靶向以校正或调节生理过程。在一些实施例中，不同类型的能量源单独使用或彼此组合使用。在一些实施方案中，由能量源激活的生物活性剂或装置被输送到感兴趣的区域，并且能量被这种试剂增强。

9. 发明申请

US20120238919A1 NERVE TREATMENT SYSTEM 审中-公开
标题翻译：神经治疗系统
公开(公告)号：US20120238919A1
公开(公告)日：2012-09-20
申请号：US13487135
申请日：2012-06-01
申请人： Michael Gertner
发明人： Michael Gertner
IPC分类号： A61N7/00
CPC分类号： A61N2/006 , A61B5/0225 , A61B5/055 , A61B5/4035 , A61B5/4041 , A61B5/4047 , A61B5/4052 , A61B5/412 , A61B5/4528 , A61B5/4839 , A61B5/489 , A61B5/4893 , A61B6/03 , A61B6/032 , A61B6/037 , A61B6/506 , A61B8/00 , A61B8/06 , A61B8/08 , A61B8/4245 , A61B8/485 , A61B17/320068 , A61B18/14 , A61B18/18 , A61B90/37 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2090/374 , A61B2090/3762 , A61B2090/378 , A61N1/0551 , A61N5/00 , A61N5/0601 , A61N5/062 , A61N5/0622 , A61N7/00 , A61N7/02 , A61N2005/063 , A61N2007/0026 , A61N2007/003 , A61N2007/0078
摘要： In some examples, nerves surrounding arteries or leading to organs are targeted with energy sources to correct or modulate physiologic processes. In some examples, different types of energy sources are utilized singly or combined with one another. In some examples, bioactive agents or devices activated by the energy sources are delivered to the region of interest and the energy is enhanced by such agents or the agents are enhanced by the energy sources.
摘要翻译：在一些实例中，围绕动脉或通向器官的神经以能量来靶向以校正或调节生理过程。在一些示例中，不同类型的能量源单独使用或彼此组合使用。在一些实例中，由能量源激活的生物活性剂或装置被输送到感兴趣的区域，并且能量被这种试剂增强，或者这些试剂被能量源增强。

10. 发明申请

US20120177179A1 ORTHOVOLTAGE RADIOTHERAPY 有权
公开(公告)号：US20120177179A1
公开(公告)日：2012-07-12
申请号：US13345655
申请日：2012-01-06
申请人： Michael Gertner
发明人： Michael Gertner
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61B6/506 , A61B2017/306 , A61F9/009 , A61N5/1017 , A61N5/103 , A61N2005/105 , A61N2005/1056 , A61N2005/1091
摘要： Methods described herein include selecting a target disease having an associated therapeutic dose of radiation, determining a maximal energy in an x-ray radiation beam to be emitted from a radiotherapy system to deliver a therapeutic dose of radiation associated with the target disease to target tissue in a patient, the selected disease of the plurality of diseases requiring differing maximal energies of the x-ray radiation beam to achieve the associated therapeutic dose of radiation than the maximal energy required to achieve the associated therapeutic dose of radiation for another disease, and outputting to an output module an indication of the determined maximal energy. Methods carried out in a system that can include a processing module that receives an input including a selection of a target disease, and an output module, coupled to the processing module, that outputs, an indication of the determined maximal energy.
摘要翻译：本文描述的方法包括选择具有相关联的治疗剂量的辐射的靶疾病，确定要从放射治疗系统发射的x射线辐射束中的最大能量，以将与靶疾病相关的治疗剂量的放射线递送至靶组织患者，所选择的多种疾病需要X射线辐射束的最大能量的不同以达到与实现相关治疗剂量的另一种疾病的辐射所需的最大能量相关联的治疗剂量的辐射，并输出至输出模块指示确定的最大能量。在可以包括接收包括目标疾病选择的输入的处理模块的系统中执行的方法以及耦合到处理模块的输出模块，其输出所确定的最大能量的指示。

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