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1. 发明授权

US06403865B1 Method of producing transgenic maize using direct transformation of commercially important genotypes 失效
标题翻译：使用商业上重要的基因型的直接转化生产转基因玉米的方法
公开(公告)号：US06403865B1
公开(公告)日：2002-06-11
申请号：US08438666
申请日：1995-05-10
申请人： Michael G. Koziel , Nalini M. Desai , Kelly S. Lewis , Vance C. Kramer , Gregory W. Warren , Stephen V. Evola , Lyle D. Crossland , Martha S. Wright , Ellis J. Merlin , Karen L. Launis , Steven J. Rothstein , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie , Nadine Carozzi , Annick De Framond , James O. Linder , Robert L. Miller , Bruce W. Skillings , Alan W. Mousel , Albert R. Hornbrook , Christopher P. Clucas , Moez Rajabali Meghji , Andreas H. Tanner , Francis E. Cassagne , Gilles Pollini , Terry Ray Colbert , Francis P. Cammack
发明人： Michael G. Koziel , Nalini M. Desai , Kelly S. Lewis , Vance C. Kramer , Gregory W. Warren , Stephen V. Evola , Lyle D. Crossland , Martha S. Wright , Ellis J. Merlin , Karen L. Launis , Steven J. Rothstein , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie , Nadine Carozzi , Annick De Framond , James O. Linder , Robert L. Miller , Bruce W. Skillings , Alan W. Mousel , Albert R. Hornbrook , Christopher P. Clucas , Moez Rajabali Meghji , Andreas H. Tanner , Francis E. Cassagne , Gilles Pollini , Terry Ray Colbert , Francis P. Cammack
IPC分类号： A01H500
CPC分类号： C12N9/12 , C07K14/325 , C12N9/88 , C12N15/8286 , Y02A40/162
摘要： Methods for transformation of maize with nucleic acid sequences of interest are disclosed. The method involves subjecting immature zygotic embryos or Type I callus to high velocity microprojectile bombardment. The method is capable of producing transformed maize lines of commercial importance and their hybrid combinations.
摘要翻译：公开了用感兴趣的核酸序列转化玉米的方法。该方法包括使未成熟的合子胚或I型愈伤组织进行高速微粒轰击。该方法能够生产具有商业重要性的转化玉米品系及其杂交组合。

2. 发明授权

US5625136A Synthetic DNA sequence having enhanced insecticidal activity in maize 失效
标题翻译：在玉米中具有增强的杀虫活性的合成DNA序列
公开(公告)号：US5625136A
公开(公告)日：1997-04-29
申请号：US951715
申请日：1992-09-25
申请人： Michael G. Koziel , Nalini M. Desai , Kelly S. Lewis , Vance C. Kramer , Gregory W. Warren , Stephen V. Evola , Lyle D. Crossland , Martha S. Wright , Ellis J. Merlin , Karen L. Launis , Steven J. Rothstein , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie
发明人： Michael G. Koziel , Nalini M. Desai , Kelly S. Lewis , Vance C. Kramer , Gregory W. Warren , Stephen V. Evola , Lyle D. Crossland , Martha S. Wright , Ellis J. Merlin , Karen L. Launis , Steven J. Rothstein , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie
IPC分类号： A01H5/00 , A01H5/10 , C07H21/04 , C07K14/325 , C12N5/04 , C12N9/12 , C12N9/88 , C12N15/09 , C12N15/11 , C12N15/32 , C12N15/54 , C12N15/60 , C12N15/82 , C12N15/87
CPC分类号： C07K14/325 , C12N15/8286 , C12N9/12 , C12N9/88
摘要： DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
摘要翻译：公开了优化用于在植物中表达的DNA序列。 DNA序列优选编码杀虫多肽，特别是来自苏云金芽孢杆菌的杀虫蛋白。还提供植物启动子，特定组织特异性和组织优选启动子。另外公开了包含所述DNA序列的转化载体。转化载体在转化为玉米时表现出高水平的杀虫活性。

3. 发明授权

US5859336A Synthetic DNA sequence having enhanced activity in maize 失效
标题翻译：在玉米中具有增强活性的合成DNA序列
公开(公告)号：US5859336A
公开(公告)日：1999-01-12
申请号：US459448
申请日：1995-06-02
申请人： Michael G. Koziel , Nalini M. Desai , Kelly S. Lewis , Gregory W. Warren , Stephen V. Evola , Lyle D. Crossland , Martha S. Wright , Ellis J. Merlin , Karen L. Launis , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie
发明人： Michael G. Koziel , Nalini M. Desai , Kelly S. Lewis , Gregory W. Warren , Stephen V. Evola , Lyle D. Crossland , Martha S. Wright , Ellis J. Merlin , Karen L. Launis , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie
IPC分类号： A01H5/00 , A01H5/10 , C07H21/04 , C07K14/325 , C12N5/04 , C12N9/12 , C12N9/88 , C12N15/09 , C12N15/11 , C12N15/32 , C12N15/54 , C12N15/60 , C12N15/82 , C12N15/87 , C12N15/63
CPC分类号： C07K14/325 , C12N15/8286 , C12N9/12 , C12N9/88
摘要： DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
摘要翻译：公开了优化用于在植物中表达的DNA序列。 DNA序列优选编码杀虫多肽，特别是来自苏云金芽孢杆菌的杀虫蛋白。还提供植物启动子，特定组织特异性和组织优选启动子。另外公开了包含所述DNA序列的转化载体。转化载体在转化为玉米时表现出高水平的杀虫活性。

4. 发明授权

US6018104A Nucleic acid promoter fragment isolated from a plant tryptophan synthase alpha subunit (trpA) gene 失效
标题翻译：从植物色氨酸合酶α亚基（trpA）基因分离的核酸启动子片段
公开(公告)号：US6018104A
公开(公告)日：2000-01-25
申请号：US459595
申请日：1995-06-02
申请人： Michael G. Koziel , Nalini M. Desai , Kelly S. Lewis , Vance C. Kramer , Gregory W. Warren , Stephen V. Evola , Martha S. Wright , Karen L. Launis , Steven J. Rothstein , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie
发明人： Michael G. Koziel , Nalini M. Desai , Kelly S. Lewis , Vance C. Kramer , Gregory W. Warren , Stephen V. Evola , Martha S. Wright , Karen L. Launis , Steven J. Rothstein , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie
IPC分类号： A01H5/00 , A01H5/10 , C07H21/04 , C07K14/325 , C12N5/04 , C12N9/12 , C12N9/88 , C12N15/09 , C12N15/11 , C12N15/32 , C12N15/54 , C12N15/60 , C12N15/82 , C12N15/87
CPC分类号： C07K14/325 , C12N15/8286 , C12N9/12 , C12N9/88
摘要： DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
摘要翻译：公开了优化用于在植物中表达的DNA序列。 DNA序列优选编码杀虫多肽，特别是来自苏云金芽孢杆菌的杀虫蛋白。还提供植物启动子，特定组织特异性和组织优选启动子。另外公开了包含所述DNA序列的转化载体。转化载体在转化为玉米时表现出高水平的杀虫活性。

5. 发明授权

US6075185A Synthetic DNA sequence having enhanced insecticidal activity in maize 失效
公开(公告)号：US6075185A
公开(公告)日：2000-06-13
申请号：US459504
申请日：1995-06-02
申请人： Michael G. Koziel , Nalini M. Desai , Kelly S. Lewis , Gregory W. Warren , Stephen V. Evola , Martha S. Wright , Karen L. Launis , Steven J. Rothstein , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie
发明人： Michael G. Koziel , Nalini M. Desai , Kelly S. Lewis , Gregory W. Warren , Stephen V. Evola , Martha S. Wright , Karen L. Launis , Steven J. Rothstein , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie
IPC分类号： A01H5/00 , A01H5/10 , C07H21/04 , C07K14/325 , C12N5/04 , C12N9/12 , C12N9/88 , C12N15/09 , C12N15/11 , C12N15/32 , C12N15/54 , C12N15/60 , C12N15/82 , C12N15/87
CPC分类号： C07K14/325 , C12N15/8286 , C12N9/12 , C12N9/88
摘要： DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.

6. 发明授权

US06320100B1 Synthetic DNA sequences having enhanced insecticidal activity in maize 失效
标题翻译：在玉米中具有增强的杀虫活性的合成DNA序列
公开(公告)号：US06320100B1
公开(公告)日：2001-11-20
申请号：US09547422
申请日：2000-04-11
申请人： Michael G. Koziel , Nalini M. Desai , Kelly S. Lewis , Gregory W. Warren , Stephen V. Evola , Martha S. Wright , Karen L. Launis , Steven J. Rothstein , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie
发明人： Michael G. Koziel , Nalini M. Desai , Kelly S. Lewis , Gregory W. Warren , Stephen V. Evola , Martha S. Wright , Karen L. Launis , Steven J. Rothstein , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie
IPC分类号： A01H500
CPC分类号： C07K14/325 , C12N9/12 , C12N9/88 , C12N15/8286 , Y02A40/162
摘要： DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
摘要翻译：公开了优化用于在植物中表达的DNA序列。 DNA序列优选编码杀虫多肽，特别是来自苏云金芽孢杆菌的杀虫蛋白。还提供植物启动子，特定组织特异性和组织优选启动子。另外公开了包含所述DNA序列的转化载体。转化载体在转化为玉米时表现出高水平的杀虫活性。

7. 发明授权

US6051760A Synthetic DNA sequence having enhanced insecticidal activity in maize 失效
公开(公告)号：US6051760A
公开(公告)日：2000-04-18
申请号：US460408
申请日：1995-06-02
申请人： Michael G. Koziel , Nalini M. Desai , Gregory W. Warren , Stephen V. Evola , Martha S. Wright , Karen L. Launis , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie
发明人： Michael G. Koziel , Nalini M. Desai , Gregory W. Warren , Stephen V. Evola , Martha S. Wright , Karen L. Launis , Cindy G. Bowman , John L. Dawson , Erik M. Dunder , Gary M. Pace , Janet L. Suttie
IPC分类号： A01H5/00 , A01H5/10 , C07H21/04 , C07K14/325 , C12N5/04 , C12N9/12 , C12N9/88 , C12N15/09 , C12N15/11 , C12N15/32 , C12N15/54 , C12N15/60 , C12N15/82 , C12N15/87
CPC分类号： C07K14/325 , C12N15/8286 , C12N9/12 , C12N9/88
摘要： DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.

8. 发明授权

US06720488B2 Transgenic maize seed and method for controlling insect pests 失效
标题翻译：转基因玉米种子和防治害虫的方法
公开(公告)号：US06720488B2
公开(公告)日：2004-04-13
申请号：US09988462
申请日：2001-11-20
申请人： Michael Koziel , Nalini Desai , Gary M. Pace , Jan Suttie , Nadine Carozzi , Cindy Boyce , John L. Dawson , Erik Dunder , Martha Wright , Karen Launis , Steven J. Rothstein , Kelly Lewis , Gregory Warren , Steve Evola
发明人： Michael Koziel , Nalini Desai , Gary M. Pace , Jan Suttie , Nadine Carozzi , Cindy Boyce , John L. Dawson , Erik Dunder , Martha Wright , Karen Launis , Steven J. Rothstein , Kelly Lewis , Gregory Warren , Steve Evola
IPC分类号： A01H510
CPC分类号： C07K14/325 , C12N9/12 , C12N9/88 , C12N15/8286 , Y02A40/162
摘要： DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
摘要翻译：公开了优化用于在植物中表达的DNA序列。 DNA序列优选编码杀虫多肽，特别是来自苏云金芽孢杆菌的杀虫蛋白。还提供植物启动子，特定组织特异性和组织优选启动子。另外公开了包含所述DNA序列的转化载体。转化载体在转化为玉米时表现出高水平的杀虫活性。

9. 发明授权

US5139627A Corrosion monitoring 失效
标题翻译：腐蚀监测
公开(公告)号：US5139627A
公开(公告)日：1992-08-18
申请号：US272693
申请日：1990-11-14
申请人： David A. Eden , David G. John , John L. Dawson
发明人： David A. Eden , David G. John , John L. Dawson
IPC分类号： G01N17/00 , G01N17/02
CPC分类号： G01N17/02
摘要： A method and apparatus for detecting and measuring localized corrosion of a metallic surface is described. An array of electrodes fabricated from the same material as the metallic surface is exposed to the same corrosion conditions as the metallic surface. The coupling current between two electrodes of the array is measured, and the electrochemical current noise originating in the electrode array is measured. The two measurements are compared, the electrochemical current noise increasing as compared to the coupling current as the degree to which corrosion is localized increases. The electrochemical current noise originating in the coupled array electrode and the associated electrochemical corrosion potential noise are produced by the natural corrosion processes. The corrosion current is measured by comparison or correlation of the electrochemical current noise and the electrochemical potential noise, the electrochemical potential being measured by means of a third electrode in the array, a reference electrode or a relatively inert electrode. Comparison or correlation of the electrochemical potential noise to the electrochemical current noise provides a resistive noise or impedance, which is inversely proportional to the corrosion current. The corrosion measurement or metal penetration rate is then obtained from the measured corrosion current, as provided by the resistive noise or impedance noise determination, but modified by the degree of localization, as measured by the electrochemical current noise and coupling current determinations.
摘要翻译： PCT No.PCT / GB87 / 00310 Sec。 371日期1990年11月14日第 102（e）1990年11月14日日期PCT提交1987年5月11日PCT公布。第WO87 / 07022号公报日期：1987年11月19日。描述了用于检测和测量金属表面的局部腐蚀的方法和装置。由与金属表面相同的材料制成的电极阵列暴露于与金属表面相同的腐蚀条件。测量阵列的两个电极之间的耦合电流，并测量源自电极阵列的电化学电流噪声。比较两个测量结果，与腐蚀局部化程度相比，耦合电流的电化学电流噪声增加。源自耦合的阵列电极的电化学电流噪声和相关的电化学腐蚀电位噪声是由天然腐蚀过程产生的。腐蚀电流通过电化学电流噪声和电化学电位噪声的比较或相关性来测量，电化学电位通过阵列中的第三电极，参考电极或相对惰性电极测量。电化学势噪声与电化学电流噪声的比较或相关性提供了电阻噪声或阻抗，其与腐蚀电流成反比。然后根据电阻噪声或阻抗噪声测定提供的测量腐蚀电流获得腐蚀测量或金属渗透率，但是通过电化学电流噪声和耦合电流测定测量的定位程度进行修改。

10. 发明授权

US5030045A Scored panel 失效
标题翻译：评分面板
公开(公告)号：US5030045A
公开(公告)日：1991-07-09
申请号：US519798
申请日：1990-05-07
申请人： John L. Dawson , David L. Bridges
发明人： John L. Dawson , David L. Bridges
IPC分类号： B44F11/06 , E04F13/16
CPC分类号： E04F13/16 , B44F11/06 , Y10T409/303752
摘要： A scored wall panel provides shallow grooves to simulate installed wall tile or the like. The shallow grooves are provided with an inner concave wall having a radius of curvature substantially exceeding the thickness of the panel and corners tangentially intersecting the inner wall having a radius of curvature substantially less than the thickness of the panel. The panel thickness varies from one location to another and the grooves are formed so that the variations in thickness of the panel do not cause variations in the width of the grooves. Further, the grooves are sufficiently shallow so that the material of the panel extending past the groove maintains necessary panel strength. The edges of the radiused corners remote from the inner surface of the grooves extend substantially perpendicular to the faces of the panel and are spaced from the rearward face of the panel by a distance substantially equal to the minimum thickness of the panel. The grooves provide surfaces substantially perpendicular to the panel faces extending from the front face to the adjacent edges of the radiused corners along those portions of the panel which have a thickness greater than the minimum thickness thereof. The panel is particularly suited where sanitation requires that the grooves can be easily and effectively cleaned, such as along kitchen and bathroom walls.
摘要翻译：刻痕墙板提供浅槽以模拟安装的墙砖等。浅槽设置有内凹壁，其具有基本上超过面板厚度的曲率半径，并且与内壁相切切线的角部具有基本上小于面板厚度的曲率半径。面板厚度从一个位置到另一个位置不同，并且形成凹槽，使得面板的厚度变化不会引起凹槽宽度的变化。此外，凹槽足够浅，使得延伸通过凹槽的面板的材料保持所需的面板强度。远离槽的内表面的圆角的边缘基本上垂直于面板的表面延伸，并且与面板的后表面间隔大致等于面板的最小厚度。凹槽提供基本上垂直于面板表面的表面，所述表面沿着具有大于其最小厚度的厚度的板的那些部分从正面延伸到圆角拐角的相邻边缘。面板特别适用于卫生要求可以容易且有效地清洁凹槽，例如沿着厨房和浴室墙壁。

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