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1. 发明申请

US20120165850A1 Spring Action Medical Device 有权
标题翻译：弹簧动作医疗器械
公开(公告)号：US20120165850A1
公开(公告)日：2012-06-28
申请号：US13379975
申请日：2010-07-08
申请人： Michael D. Deckard , Michael W. Hardert , Thomas A. Kay, JR. , William F. Moore , James C. Elsesser , David C. Lentz , Jeffry S. Melsheimer
发明人： Michael D. Deckard , Michael W. Hardert , Thomas A. Kay, JR. , William F. Moore , James C. Elsesser , David C. Lentz , Jeffry S. Melsheimer
IPC分类号： A61B17/34
CPC分类号： A61M25/09025 , A61B17/22012 , A61B2017/22038 , A61B2017/22069 , A61B2017/22094
摘要： A spring action medical device includes a spring that may propel a hammer component in a distal direction when the spring is released from a loaded state. When propelled forward by the spring, the hammer component makes contact with a distal tip of the medical device. The distal tip may then transfer a force to an external object, such as an occlusion in a body lumen.
摘要翻译：弹簧动作医疗装置包括弹簧，当弹簧从负载状态释放时，弹簧可以沿远侧方向推进锤部件。当弹簧向前推进时，锤子部件与医疗装置的远端接触。然后，远侧末端可以将力传递到外部物体，例如体腔内的闭塞。

2. 发明授权

US09108026B2 Spring action medical device 有权
标题翻译：弹簧动作医疗器械
公开(公告)号：US09108026B2
公开(公告)日：2015-08-18
申请号：US13379975
申请日：2010-07-08
申请人： Michael D. Deckard , Michael W. Hardert , Thomas A. Kay, Jr. , William F. Moore , James C. Elsesser , David C. Lentz , Jeffry S. Melsheimer
发明人： Michael D. Deckard , Michael W. Hardert , Thomas A. Kay, Jr. , William F. Moore , James C. Elsesser , David C. Lentz , Jeffry S. Melsheimer
IPC分类号： A61B17/34 , A61M25/09 , A61B17/22
CPC分类号： A61M25/09025 , A61B17/22012 , A61B2017/22038 , A61B2017/22069 , A61B2017/22094
摘要： A spring action medical device includes a spring that may propel a hammer component in a distal direction when the spring is released from a loaded state. When propelled forward by the spring, the hammer component makes contact with a distal tip of the medical device. The distal tip may then transfer a force to an external object, such as an occlusion in a body lumen.
摘要翻译：弹簧动作医疗装置包括弹簧，当弹簧从负载状态释放时，弹簧可以沿远侧方向推进锤部件。当弹簧向前推进时，锤子部件与医疗装置的远端接触。然后，远侧末端可以将力传递到外部物体，例如体腔内的闭塞。

3. 发明申请

US20110295228A1 MINIMALLY INVASIVE MEDICAL DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC OR DIAGNOSTIC AGENTS INTO A VESSEL WALL 有权
标题翻译：最小的入侵医疗装置和将治疗或诊断代谢物输送到血管壁的方法
公开(公告)号：US20110295228A1
公开(公告)日：2011-12-01
申请号：US13209145
申请日：2011-08-12
申请人： Brad Shirley , Grant T. Hoffman , Michael W. Hardert , Jeffry S. Melsheimer
发明人： Brad Shirley , Grant T. Hoffman , Michael W. Hardert , Jeffry S. Melsheimer
IPC分类号： A61M31/00
CPC分类号： A61M25/0084
摘要： The invention relates to minimally invasive device for delivering therapeutic or diagnostic agents into a vessel wall. The device includes an introducer tube, a tubular member having a proximal end, a distal end, and a first lumen extending therebetween, the tubular member being slidably disposed within the introducer tube; a plurality of hollow delivery struts, each delivery strut adapted to pierce through inner most layers of the vessel wall and each comprising at least one exit port and at least one stopper to prevent the delivery strut from piercing through the outer most layers of the vessel wall. The delivery struts are disposed on the distal end of the tubular member and are in fluid communication with the first lumen. The invention also relates to methods of delivering the device of this invention and methods of treating conditions or diseases of body lumens.
摘要翻译：本发明涉及用于将治疗剂或诊断剂递送到血管壁中的微创装置。所述装置包括导引管，管状构件，其具有近端，远端和在其间延伸的第一腔，所述管状构件可滑动地设置在所述导引管内; 多个中空输送支柱，每个输送支柱适于刺穿血管壁的最内层，并且每个输送支柱包括至少一个出口和至少一个塞子，以防止输送支柱穿过血管壁的最外层。输送支柱设置在管状构件的远端上并与第一腔流体连通。本发明还涉及递送本发明的装置的方法和治疗体腔的病症或疾病的方法。

4. 发明申请

US20090018638A1 Minimally invasive medical device and method for delivery of therapeutic or diagnostic agents into a vessel wall 有权
标题翻译：用于将治疗剂或诊断剂递送到血管壁的微创医疗装置和方法
公开(公告)号：US20090018638A1
公开(公告)日：2009-01-15
申请号：US11827219
申请日：2007-07-10
申请人： Brad Shirley , Grant T. Hoffman , Michael W. Hardert , Jeffry S. Melsheimer
发明人： Brad Shirley , Grant T. Hoffman , Michael W. Hardert , Jeffry S. Melsheimer
IPC分类号： A61F2/06 , A61M31/00 , A61M5/178
CPC分类号： A61M25/0084
摘要： The invention relates to minimally invasive device for delivering therapeutic or diagnostic agents into a vessel wall. The device includes an introducer tube, a tubular member having a proximal end, a distal end, and a first lumen extending therebetween, the tubular member being slidably disposed within the introducer tube; a plurality of hollow delivery struts, each delivery strut adapted to pierce through inner most layers of the vessel wall and each comprising at least one exit port and at least one stopper to prevent the delivery strut from piercing through the outer most layers of the vessel wall. The delivery struts are disposed on the distal end of the tubular member and are in fluid communication with the first lumen. The invention also relates to methods of delivering the device of this invention and methods of treating conditions or diseases of body lumens.
摘要翻译：本发明涉及用于将治疗剂或诊断剂递送到血管壁中的微创装置。所述装置包括导引管，管状构件，其具有近端，远端和在其间延伸的第一腔，所述管状构件可滑动地设置在所述导引管内; 多个中空输送支柱，每个输送支柱适于刺穿血管壁的最内层，并且每个输送支柱包括至少一个出口和至少一个塞子，以防止输送支柱穿过血管壁的最外层。输送支柱设置在管状构件的远端上并与第一腔流体连通。本发明还涉及递送本发明的装置的方法和治疗体腔的病症或疾病的方法。

5. 发明申请

US20100076543A1 Multi-strand helical stent 有权
标题翻译：多股螺旋支架
公开(公告)号：US20100076543A1
公开(公告)日：2010-03-25
申请号：US12584176
申请日：2009-08-31
申请人： Jeffry S. Melsheimer , Kurt J. Tekulve , Mark R. Frye , James M. Carlson , Richard J. Godlewski , Michael W. Hardert , Jessica L. Burke
发明人： Jeffry S. Melsheimer , Kurt J. Tekulve , Mark R. Frye , James M. Carlson , Richard J. Godlewski , Michael W. Hardert , Jessica L. Burke
IPC分类号： A61F2/06 , A61F2/82
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2220/0075
摘要： A stent including a stent wire comprising a plurality of filaments twisted into a bundle having a helix, the stent wire bent into a pattern having a plurality of substantially straight wire sections separated by a plurality of bends. The pattern of the stent wire is spirally wound about a central axis in the same direction as the helix formed by the plurality of filaments. Each of the filaments in a bend have a cylindrical cross-section where at least one of the plurality of filaments is displaced and spaced from an immediately adjacent filament in the bend.
摘要翻译：一种支架，其包括支架线，所述支架线包括扭曲成具有螺旋线的多个细丝，所述支架线弯曲成具有由多个弯曲部分开的多个基本上直的线部分的图案。支架丝线的图案围绕中心轴线以与由多个细丝形成的螺旋线相同的方向螺旋卷绕。弯曲中的每个细丝具有圆柱形横截面，其中多个细丝中的至少一个丝线与弯曲部中紧邻的细丝位移并间隔开。

6. 发明授权

US08007470B2 Minimally invasive medical device and method for delivery of therapeutic or diagnostic agents into a vessel wall 有权
标题翻译：用于将治疗剂或诊断剂递送到血管壁的微创医疗装置和方法
公开(公告)号：US08007470B2
公开(公告)日：2011-08-30
申请号：US11827219
申请日：2007-07-10
申请人： Brad Shirley , Grant T. Hoffman , Michael W. Hardert , Jeffry S. Melsheimer
发明人： Brad Shirley , Grant T. Hoffman , Michael W. Hardert , Jeffry S. Melsheimer
IPC分类号： A61M5/178
CPC分类号： A61M25/0084
摘要： The invention relates to minimally invasive device for delivering therapeutic or diagnostic agents into a vessel wall. The device includes an introducer tube, a tubular member having a proximal end, a distal end, and a first lumen extending therebetween, the tubular member being slidably disposed within the introducer tube; a plurality of hollow delivery struts, each delivery strut adapted to pierce through inner most layers of the vessel wall and each comprising at least one exit port and at least one stopper to prevent the delivery strut from piercing through the outer most layers of the vessel wall. The delivery struts are disposed on the distal end of the tubular member and are in fluid communication with the first lumen. The invention also relates to methods of delivering the device of this invention and methods of treating conditions or diseases of body lumens.
摘要翻译：本发明涉及用于将治疗剂或诊断剂递送到血管壁中的微创装置。所述装置包括导引管，管状构件，其具有近端，远端和在其间延伸的第一腔，所述管状构件可滑动地设置在所述导引管内; 多个中空输送支柱，每个输送支柱适于刺穿血管壁的最内层，并且每个输送支柱包括至少一个出口和至少一个塞子，以防止输送支柱穿过血管壁的最外层。输送支柱设置在管状构件的远端上并与第一腔流体连通。本发明还涉及递送本发明的装置的方法和治疗体腔的病症或疾病的方法。

7. 发明授权

US08394138B2 Multi-strand helical stent 有权
标题翻译：多股螺旋支架
公开(公告)号：US08394138B2
公开(公告)日：2013-03-12
申请号：US12584176
申请日：2009-08-31
申请人： Jeffry S. Melsheimer , Kurt J. Tekulve , Mark R. Frye , James M. Carlson , Richard J. Godlewski , Michael W. Hardert , Jessica L. Burke
发明人： Jeffry S. Melsheimer , Kurt J. Tekulve , Mark R. Frye , James M. Carlson , Richard J. Godlewski , Michael W. Hardert , Jessica L. Burke
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2220/0075
摘要： A stent including a stent wire comprising a plurality of filaments twisted into a bundle having a helix, the stent wire bent into a pattern having a plurality of substantially straight wire sections separated by a plurality of bends. The pattern of the stent wire is spirally wound about a central axis in the same direction as the helix formed by the plurality of filaments. Each of the filaments in a bend have a cylindrical cross-section where at least one of the plurality of filaments is displaced and spaced from an immediately adjacent filament in the bend.
摘要翻译：一种支架，其包括支架线，所述支架线包括扭曲成具有螺旋线的多个细丝，所述支架线弯曲成具有由多个弯曲部分开的多个基本上直的线部分的图案。支架丝线的图案围绕中心轴线以与由多个细丝形成的螺旋线相同的方向螺旋卷绕。弯曲中的每个细丝具有圆柱形横截面，其中多个细丝中的至少一个丝线与弯曲部中紧邻的细丝位移并间隔开。

8. 发明申请

US20120172913A1 DELIVERY OF AN EMBOLIZATION COIL WITH AN ATTACHER 审中-公开
标题翻译：交付带有附件的嵌入式线圈
公开(公告)号：US20120172913A1
公开(公告)日：2012-07-05
申请号：US13338739
申请日：2011-12-28
申请人： Michael R. Kurrus , William F. Moore , Jeffry S. Melsheimer , Kathryn R. Evert
发明人： Michael R. Kurrus , William F. Moore , Jeffry S. Melsheimer , Kathryn R. Evert
IPC分类号： A61F2/01
CPC分类号： A61B17/12022 , A61B2017/00477 , A61B2017/00871 , A61B2017/12054 , A61B2017/12095
摘要： An occluding device apparatus includes an embolization coil with a distal end and a proximal end with an opening and an attacher that is threaded through the opening at the proximal end of the embolization coil. The apparatus further comprises a delivery kit for delivery of the embolization coil in a body cavity. The kit comprises a guide catheter for percutaneous introduction of the embolization coil and an inner catheter slidably disposed within the guide catheter during insertion. The inner catheter comprises a proximal end and a distal end. The inner catheter further includes a hub disposed adjacent the proximal end. The kit further comprises a guide wire slidably disposed within the inner catheter. The guide wire is configured to provide a path during insertion thereof within a body cavity. The kit further comprises a pushwire to advance the embolization coil through the inner catheter.
摘要翻译：闭塞装置装置包括具有远端的栓塞线圈和具有开口的近端和穿过栓塞线圈的近端处的开口的附件。该装置还包括用于在体腔中输送栓塞线圈的递送套件。该套件包括用于经皮引入栓塞线圈的引导导管和在插入期间可滑动地设置在引导导管内的内导管。内导管包括近端和远端。内导管还包括邻近近端设置的毂。套件还包括可滑动地设置在内导管内的导丝。引导线被配置成在将其插入体腔内时提供路径。套件还包括推动栓塞线圈穿过内导管的推挽线。

9. 发明授权

US09623206B2 Catheter having a selectively variable degree of flexibility 有权
公开(公告)号：US09623206B2
公开(公告)日：2017-04-18
申请号：US13460231
申请日：2012-04-30
申请人： Jeffry S. Melsheimer
发明人： Jeffry S. Melsheimer
IPC分类号： A61M25/00 , A61B17/34 , A61M25/01
CPC分类号： A61M25/005 , A61B17/3439 , A61M25/0012 , A61M25/0051 , A61M25/0052 , A61M25/0053 , A61M25/0054 , A61M25/0097 , A61M25/01 , A61M2025/0004 , A61M2025/0006 , A61M2025/0024 , A61M2025/0025 , A61M2025/0059 , A61M2025/0062 , A61M2025/0063 , A61M2025/0175
摘要： A catheter having a selectively variable degree of flexibility includes an elongate tubular outer member and an elongate tubular inner member disposed within the outer member. The catheter further includes a cavity disposed in between the outer and inner members. A tubular braid of filaments may be disposed within the cavity. The outer and inner members are movable relative to each other along intermediate portions thereof when in a first configuration, and are not movable relative to each other when in a second configuration. When the inner and outer members are in the first configuration, the tubular braid of filaments is movably disposed relative to at least one of the outer member and the inner member. When the inner and outer members are in the second configuration, the inner and outer members clamp the tubular braid of filaments in a fixed position relative to the inner and outer members.

10. 发明授权

US09408600B2 Releasable suture clamp and suture anchor assembly including same 有权
标题翻译：可释放的缝合夹和包括其的缝合锚组件
公开(公告)号：US09408600B2
公开(公告)日：2016-08-09
申请号：US13761571
申请日：2013-02-07
申请人： Jeffry S. Melsheimer , Kristyn Gadlage
发明人： Jeffry S. Melsheimer , Kristyn Gadlage
IPC分类号： A61B17/04 , A61B17/06
CPC分类号： A61B17/0401 , A61B17/0487 , A61B17/06114 , A61B50/20 , A61B2017/0417 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052
摘要： A suture anchor assembly includes a length of suture having an anchor attached to an end thereof. A releasable suture clamp is disposed in a clamped configuration about the suture. The releasable suture clamp includes a plurality of independent stackable components rotatable about a common axis, which is transverse to opposing faces of the stackable components. Each of the stackable components has a first opening passing through the opposing faces, spaced from the common axis, and sized for receiving the suture therethrough. The releasable suture clamp has an unclamped configuration in which the first openings are aligned relative to an alignment axis and the clamped configuration in which the first openings are misaligned relative to the alignment axis, wherein the alignment axis is parallel to the common axis.
摘要翻译：缝合锚固组件包括具有连接到其一端的锚定物的一段缝合线。可释放的缝线夹以围绕缝合线的夹紧构型设置。可释放的缝合夹具包括多个独立的可叠置部件，可绕公共轴线旋转，该公共轴线横向于可堆叠部件的相对面。每个可堆叠组件具有穿过相对面的第一开口，与公共轴线间隔开，并且其尺寸适于接收穿过其中的缝合线。可释放的缝合夹具具有未夹紧的构造，其中第一开口相对于对准轴线对准，并且夹持构造，其中第一开口相对于对准轴线不对准，其中对准轴线平行于公共轴线。

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