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1. 发明申请

US20100076543A1 Multi-strand helical stent 有权
标题翻译：多股螺旋支架
公开(公告)号：US20100076543A1
公开(公告)日：2010-03-25
申请号：US12584176
申请日：2009-08-31
申请人： Jeffry S. Melsheimer , Kurt J. Tekulve , Mark R. Frye , James M. Carlson , Richard J. Godlewski , Michael W. Hardert , Jessica L. Burke
发明人： Jeffry S. Melsheimer , Kurt J. Tekulve , Mark R. Frye , James M. Carlson , Richard J. Godlewski , Michael W. Hardert , Jessica L. Burke
IPC分类号： A61F2/06 , A61F2/82
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2220/0075
摘要： A stent including a stent wire comprising a plurality of filaments twisted into a bundle having a helix, the stent wire bent into a pattern having a plurality of substantially straight wire sections separated by a plurality of bends. The pattern of the stent wire is spirally wound about a central axis in the same direction as the helix formed by the plurality of filaments. Each of the filaments in a bend have a cylindrical cross-section where at least one of the plurality of filaments is displaced and spaced from an immediately adjacent filament in the bend.
摘要翻译：一种支架，其包括支架线，所述支架线包括扭曲成具有螺旋线的多个细丝，所述支架线弯曲成具有由多个弯曲部分开的多个基本上直的线部分的图案。支架丝线的图案围绕中心轴线以与由多个细丝形成的螺旋线相同的方向螺旋卷绕。弯曲中的每个细丝具有圆柱形横截面，其中多个细丝中的至少一个丝线与弯曲部中紧邻的细丝位移并间隔开。

2. 发明授权

US08394138B2 Multi-strand helical stent 有权
标题翻译：多股螺旋支架
公开(公告)号：US08394138B2
公开(公告)日：2013-03-12
申请号：US12584176
申请日：2009-08-31
申请人： Jeffry S. Melsheimer , Kurt J. Tekulve , Mark R. Frye , James M. Carlson , Richard J. Godlewski , Michael W. Hardert , Jessica L. Burke
发明人： Jeffry S. Melsheimer , Kurt J. Tekulve , Mark R. Frye , James M. Carlson , Richard J. Godlewski , Michael W. Hardert , Jessica L. Burke
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2220/0075
摘要： A stent including a stent wire comprising a plurality of filaments twisted into a bundle having a helix, the stent wire bent into a pattern having a plurality of substantially straight wire sections separated by a plurality of bends. The pattern of the stent wire is spirally wound about a central axis in the same direction as the helix formed by the plurality of filaments. Each of the filaments in a bend have a cylindrical cross-section where at least one of the plurality of filaments is displaced and spaced from an immediately adjacent filament in the bend.
摘要翻译：一种支架，其包括支架线，所述支架线包括扭曲成具有螺旋线的多个细丝，所述支架线弯曲成具有由多个弯曲部分开的多个基本上直的线部分的图案。支架丝线的图案围绕中心轴线以与由多个细丝形成的螺旋线相同的方向螺旋卷绕。弯曲中的每个细丝具有圆柱形横截面，其中多个细丝中的至少一个丝线与弯曲部中紧邻的细丝位移并间隔开。

3. 发明授权

US08256949B2 Apparatus and method for mixing and dispensing a bone cement mixture 有权
标题翻译：用于混合和分配骨水泥混合物的装置和方法
公开(公告)号：US08256949B2
公开(公告)日：2012-09-04
申请号：US12343964
申请日：2008-12-24
申请人： Jeffry S. Melsheimer , Jonathan Lee Bennett , Jessica L. Burke
发明人： Jeffry S. Melsheimer , Jonathan Lee Bennett , Jessica L. Burke
IPC分类号： B01F7/16 , A61B17/56
CPC分类号： B01F15/0205 , A61B17/7097 , A61B17/8827 , A61B2017/8838 , B01F7/22 , B01F13/0022 , B01F15/00207 , B01F15/00435 , B01F15/00506 , B01F15/0206 , B01F15/0224 , B01F15/0279 , B01F2215/0029
摘要： Among other things, an apparatus for mixing and dispensing a bone cement mixture are provided. In certain embodiments, the apparatus includes a housing having a first chamber for containing an ampoule having a first bone cement component. The housing has a second chamber for containing a second bone cement component and the first and second chambers are in fluid communication. An ampoule breaking device is disposed within the first chamber and is configured to engage and break the ampoule for release of the first bone cement component. Disposed within the second chamber is an impeller that is configured to rotate such that the impeller mixes the first and second bone cement components together to form the bone cement mixture. Adjacent the impeller is a displacer that is configured to advance through the second chamber, receiving the impeller and dispensing the bone cement mixture.
摘要翻译：提供了一种用于混合和分配骨水泥混合物的设备。在某些实施例中，该装置包括壳体，该壳体具有用于容纳具有第一骨水泥部件的安瓿的第一腔室。壳体具有用于容纳第二骨水泥部件的第二腔室，并且第一和第二腔室处于流体连通状态。安瓿破碎装置设置在第一室内并且被构造成接合并打破安瓿以释放第一骨水泥部件。设置在第二室内的是叶轮，其构造成旋转，使得叶轮将第一和第二骨水泥部件混合在一起以形成骨粘固剂混合物。邻近叶轮是置换器，其构造成通过第二室前进，接收叶轮并分配骨水泥混合物。

4. 发明授权

US08585019B2 Loading apparatus and system for expandable intraluminal medical devices 有权
标题翻译：可扩展管腔内医疗器械的装载装置和系统
公开(公告)号：US08585019B2
公开(公告)日：2013-11-19
申请号：US12860422
申请日：2010-08-20
申请人： Jeffry S. Melsheimer , Jessica L. Burke , Sean D. Chambers , Arman Valaie
发明人： Jeffry S. Melsheimer , Jessica L. Burke , Sean D. Chambers , Arman Valaie
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/2436 , A61F2/844 , A61F2/92 , A61F2002/9511 , A61F2002/9522 , Y10T29/53843
摘要： Medical device loading apparatuses, systems, methods and kits are described. A loading apparatus comprises a main body having a proximal end defining a proximal opening, a distal end defining a distal opening, and a passageway extending between the proximal and distal openings. The passageway defines a proximal chamber having a first inner diameter, a distal chamber having a second inner diameter, and a transition chamber disposed between the proximal and distal chambers. The transition chamber has an inner diameter that transitions from the larger second inner diameter to the smaller first inner diameter. The main body has a separable connection that divides the main body between proximal and distal portions when disrupted. An expandable intraluminal medical device can be loaded into a delivery catheter using the loading apparatus by placing the device into the passageway such that it is in a radially-expanded configuration; pulling the device along an axial path through the loading apparatus such that the device transitions from the radially-expanded configuration to a radially-compressed configuration; and pushing the radially-compressed device along the axial path into the delivery catheter.
摘要翻译：描述了医疗装置装载装置，系统，方法和试剂盒。装载装置包括主体，其具有限定近端开口的近端，限定远侧开口的远端以及在近端开口和远端开口之间延伸的通道。所述通道限定具有第一内径的近侧腔室，具有第二内径的远侧腔室，以及设置在近端腔室和远端腔室之间的过渡腔室。过渡室具有从较大的第二内径向较小的第一内径转变的内径。主体具有可分离的连接，当中断时将主体分成近端部分和远端部分之间。可扩张的管腔内医疗装置可以通过将装置放置在通道中以使其处于径向展开的构型中而使用装载装置装载到输送导管中; 沿着轴向路径拉动装置通过装载装置，使得装置从径向展开的构型转变成径向压缩的构型; 并将径向压缩的装置沿轴向路径推入输送导管。

5. 发明申请

US20110046712A1 LOADING APPARATUS AND SYSTEM FOR EXPANDABLE INTRALUMINAL MEDICAL DEVICES 有权
标题翻译：用于可扩展的内镜医疗装置的装载装置和系统
公开(公告)号：US20110046712A1
公开(公告)日：2011-02-24
申请号：US12860422
申请日：2010-08-20
申请人： Jeffry S. Melsheimer , Jessica L. Burke , Sean D. Chambers , Arman Valaie
发明人： Jeffry S. Melsheimer , Jessica L. Burke , Sean D. Chambers , Arman Valaie
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/2436 , A61F2/844 , A61F2/92 , A61F2002/9511 , A61F2002/9522 , Y10T29/53843
摘要： Medical device loading apparatuses, systems, methods and kits are described. A loading apparatus comprises a main body having a proximal end defining a proximal opening, a distal end defining a distal opening, and a passageway extending between the proximal and distal openings. The passageway defines a proximal chamber having a first inner diameter, a distal chamber having a second inner diameter, and a transition chamber disposed between the proximal and distal chambers. The transition chamber has an inner diameter that transitions from the larger second inner diameter to the smaller first inner diameter. The main body has a separable connection that divides the main body between proximal and distal portions when disrupted. An expandable intraluminal medical device can be loaded into a delivery catheter using the loading apparatus by placing the device into the passageway such that it is in a radially-expanded configuration; pulling the device along an axial path through the loading apparatus such that the device transitions from the radially-expanded configuration to a radially-compressed configuration; and pushing the radially-compressed device along the axial path into the delivery catheter.
摘要翻译：描述了医疗装置装载装置，系统，方法和试剂盒。装载装置包括主体，其具有限定近端开口的近端，限定远侧开口的远端以及在近端开口和远端开口之间延伸的通道。所述通道限定具有第一内径的近侧腔室，具有第二内径的远侧腔室，以及设置在近端腔室和远端腔室之间的过渡腔室。过渡室具有从较大的第二内径向较小的第一内径转变的内径。主体具有可分离的连接，当中断时将主体分成近端部分和远端部分之间。可扩张的管腔内医疗装置可以通过将装置放置在通道中以使其处于径向展开的构型中而使用装载装置装载到输送导管中; 沿着轴向路径拉动装置通过装载装置，使得装置从径向展开的构型转变成径向压缩的构型; 并将径向压缩的装置沿轴向路径推入输送导管。

6. 发明申请

US20090171361A1 APPARATUS AND METHOD FOR MIXING AND DISPENSING A BONE CEMENT MIXTURE 有权
标题翻译：用于混合和分配骨水泥混合物的装置和方法
公开(公告)号：US20090171361A1
公开(公告)日：2009-07-02
申请号：US12343964
申请日：2008-12-24
申请人： Jeffry S. Melsheimer , Jonathan Lee Bennett , Jessica L. Burke
发明人： Jeffry S. Melsheimer , Jonathan Lee Bennett , Jessica L. Burke
IPC分类号： A61B17/58 , B01F15/02
CPC分类号： B01F15/0205 , A61B17/7097 , A61B17/8827 , A61B2017/8838 , B01F7/22 , B01F13/0022 , B01F15/00207 , B01F15/00435 , B01F15/00506 , B01F15/0206 , B01F15/0224 , B01F15/0279 , B01F2215/0029
摘要： Among other things, an apparatus for mixing and dispensing a bone cement mixture are provided. In certain embodiments, the apparatus includes a housing having a first chamber for containing an ampoule having a first bone cement component. The housing has a second chamber for containing a second bone cement component and the first and second chambers are in fluid communication. An ampoule breaking device is disposed within the first chamber and is configured to engage and break the ampoule for release of the first bone cement component. Disposed within the second chamber is an impeller that is configured to rotate such that the impeller mixes the first and second bone cement components together to form the bone cement mixture. Adjacent the impeller is a displacer that is configured to advance through the second chamber, receiving the impeller and dispensing the bone cement mixture.
摘要翻译：提供了一种用于混合和分配骨水泥混合物的设备。在某些实施例中，该装置包括壳体，该壳体具有用于容纳具有第一骨水泥部件的安瓿的第一腔室。壳体具有用于容纳第二骨水泥部件的第二腔室，并且第一和第二腔室处于流体连通状态。安瓿破碎装置设置在第一室内并且被构造成接合并打破安瓿以释放第一骨水泥部件。设置在第二室内的是叶轮，其构造成旋转，使得叶轮将第一和第二骨水泥部件混合在一起以形成骨粘固剂混合物。邻近叶轮是置换器，其构造成通过第二腔室前进，接收叶轮并分配骨水泥混合物。

7. 发明授权

US08540123B2 Apparatus and method for mixing and dispensing a bone cement mixture 有权
标题翻译：用于混合和分配骨水泥混合物的装置和方法
公开(公告)号：US08540123B2
公开(公告)日：2013-09-24
申请号：US13493015
申请日：2012-06-11
申请人： Jeffry S. Melsheimer , Jonathan Lee Bennett , Jessica L. Burke
发明人： Jeffry S. Melsheimer , Jonathan Lee Bennett , Jessica L. Burke
IPC分类号： A61B17/56
CPC分类号： B01F15/0205 , A61B17/7097 , A61B17/8827 , A61B2017/8838 , B01F7/22 , B01F13/0022 , B01F15/00207 , B01F15/00435 , B01F15/00506 , B01F15/0206 , B01F15/0224 , B01F15/0279 , B01F2215/0029
摘要： Among other things, an apparatus for mixing and dispensing a bone cement mixture are provided. In certain embodiments, the apparatus includes a housing having a first chamber for containing an ampoule having a first bone cement component. The housing has a second chamber for containing a second bone cement component and the first and second chambers are in fluid communication. An ampoule breaking device is disposed within the first chamber and is configured to engage and break the ampoule for release of the first bone cement component. Disposed within the second chamber is an impeller that is configured to rotate such that the impeller mixes the first and second bone cement components together to form the bone cement mixture. Adjacent the impeller is a displacer that is configured to advance through the second chamber, receiving the impeller and dispensing the bone cement mixture.
摘要翻译：提供了一种用于混合和分配骨水泥混合物的设备。在某些实施例中，该装置包括壳体，该壳体具有用于容纳具有第一骨水泥部件的安瓿的第一腔室。壳体具有用于容纳第二骨水泥部件的第二腔室，并且第一和第二腔室处于流体连通状态。安瓿破碎装置设置在第一室内并且被构造成接合并打破安瓿以释放第一骨水泥部件。设置在第二室内的是叶轮，其构造成旋转，使得叶轮将第一和第二骨水泥部件混合在一起以形成骨粘固剂混合物。邻近叶轮是置换器，其构造成通过第二腔室前进，接收叶轮并分配骨水泥混合物。

8. 发明申请

US20120245590A1 APPARATUS AND METHOD FOR MIXING AND DISPENSING A BONE CEMENT MIXTURE 有权
标题翻译：用于混合和分配骨水泥混合物的装置和方法
公开(公告)号：US20120245590A1
公开(公告)日：2012-09-27
申请号：US13493015
申请日：2012-06-11
申请人： Jeffry S. Melsheimer , Jonathan Lee Bennett , Jessica L. Burke
发明人： Jeffry S. Melsheimer , Jonathan Lee Bennett , Jessica L. Burke
IPC分类号： A61B17/58 , B01F15/02
CPC分类号： B01F15/0205 , A61B17/7097 , A61B17/8827 , A61B2017/8838 , B01F7/22 , B01F13/0022 , B01F15/00207 , B01F15/00435 , B01F15/00506 , B01F15/0206 , B01F15/0224 , B01F15/0279 , B01F2215/0029
摘要： Among other things, an apparatus for mixing and dispensing a bone cement mixture are provided. In certain embodiments, the apparatus includes a housing having a first chamber for containing an ampoule having a first bone cement component. The housing has a second chamber for containing a second bone cement component and the first and second chambers are in fluid communication. An ampoule breaking device is disposed within the first chamber and is configured to engage and break the ampoule for release of the first bone cement component. Disposed within the second chamber is an impeller that is configured to rotate such that the impeller mixes the first and second bone cement components together to form the bone cement mixture. Adjacent the impeller is a displacer that is configured to advance through the second chamber, receiving the impeller and dispensing the bone cement mixture.
摘要翻译：提供了一种用于混合和分配骨水泥混合物的设备。在某些实施例中，该装置包括壳体，该壳体具有用于容纳具有第一骨水泥部件的安瓿的第一腔室。壳体具有用于容纳第二骨水泥部件的第二腔室，并且第一和第二腔室处于流体连通状态。安瓿破碎装置设置在第一室内并且被构造成接合并打破安瓿以释放第一骨水泥部件。设置在第二室内的是叶轮，其构造成旋转，使得叶轮将第一和第二骨水泥部件混合在一起以形成骨粘固剂混合物。邻近叶轮是置换器，其构造成通过第二腔室前进，接收叶轮并分配骨水泥混合物。

9. 发明申请

US20100168714A1 THERAPEUTIC AGENT DELIVERY SYSTEM 审中-公开
标题翻译：治疗剂递送系统
公开(公告)号：US20100168714A1
公开(公告)日：2010-07-01
申请号：US12529898
申请日：2008-03-06
申请人： Jessica L. Burke , Grant T. Hoffman , Drew P. Lyons
发明人： Jessica L. Burke , Grant T. Hoffman , Drew P. Lyons
IPC分类号： A61M25/10
CPC分类号： A61M25/10 , A61M25/1002 , A61M2025/105 , A61M2025/1086
摘要： This present disclosure relates to a medical device and method capable of locally administering therapeutic agents efficiently. The medical device preferably includes one balloon catheter with conduits external to the balloon and with ports in the conduits where the conduits provide adequate sealing and sufficient penetration of the body vessel wall. Moreover, the placement of the conduits and location of the ports help ensure the optimal and sufficient administration of the therapeutic agent evenly to the entire treatment site. Other embodiments of the present disclosure relate to providing means to isolate the inflation medium and the therapeutic agent during administration to the treatment site and to introduce more than one therapeutic agent simultaneously to the treatment site.
摘要翻译：本公开涉及能够有效地局部施用治疗剂的医疗装置和方法。医疗装置优选地包括一个球囊导管，其具有在球囊外部的导管，并且在导管中具有导管的端口，其中导管提供足够的密封和体血管壁的充分穿透。此外，管道的放置和端口的位置有助于确保治疗剂在整个治疗部位均匀地最佳和充分地施用。本公开的其它实施方案涉及提供在施用给治疗部位期间将充气培养基和治疗剂分离并将多于一种治疗剂同时引入治疗部位的方法。

10. 发明授权

US07798999B2 Adjustable length catheter 有权
标题翻译：可调长导管
公开(公告)号：US07798999B2
公开(公告)日：2010-09-21
申请号：US11758543
申请日：2007-06-05
申请人： Frances Kristen Bailey , Jessica L. Burke , Grant T. Hoffman , Ram H. Paul, Jr.
发明人： Frances Kristen Bailey , Jessica L. Burke , Grant T. Hoffman , Ram H. Paul, Jr.
IPC分类号： A61M5/178
CPC分类号： A61M25/0097 , A61M25/0029 , A61M2025/0031 , A61M2025/0034 , A61M2025/0037
摘要： An adjustable length catheter device, a kit and a method of providing the adjustable length catheter device to a patient are provided. The catheter device includes an elongate shaft having a proximal portion, a distal portion, a first lumen and a second lumen extending at least partially therethrough. The catheter device further includes a manifold operably connected to the shaft. The manifold is configured to longitudinally move along the shaft towards the distal portion for separating the proximal portion of the shaft into a first proximal shaft portion including the first lumen and a second proximal shaft portion including the second lumen.
摘要翻译：提供了一种可调节长度的导管装置，套件以及将可调节长度的导管装置提供给患者的方法。导管装置包括细长轴，其具有近端部分，远端部分，第一内腔和至少部分延伸穿过其中的第二内腔。导管装置还包括可操作地连接到轴的歧管。歧管被构造成沿着轴朝向远端部分纵向移动，用于将轴的近端部分分离成包括第一管腔的第一近侧轴部分和包括第二管腔的第二近侧轴部分。

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