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    • 7. 发明授权
    • Control program for controlling electromagnetic radiation for cross-linking eye tissue
    • 用于控制电磁辐射用于交联眼组织的控制程序
    • US08887734B2
    • 2014-11-18
    • US13063178
    • 2009-09-10
    • Michael BüelerMichael Mrochen
    • Michael BüelerMichael Mrochen
    • A61B19/00A61B18/18G06F19/00A61B3/107A61F9/008
    • G06F19/3437A61B3/107A61F2009/00872G06F19/00G06F19/3481G16H50/50
    • A control program for controlling a source of electromagnetic radiation, with which a cross-linking in eye tissue of a patient is implemented by means of a photosensitiser introduced into the tissue in order to bring about a change in the eye tissue with reference to its form and/or one of its mechanical properties, the control program having been produced with the following steps: a) measurement data with reference to the patient and the eye are acquired, b) with the measurement data and treatment parameters, which involve a predetermined auxiliary control program for controlling the source of electromagnetic radiation, an outcome with reference to the change in the eye tissue obtained with these treatment parameters is simulated in a computer, c) the change simulated in this way is compared with a change in the eye tissue to be achieved, d) when step c) yields a sufficient agreement between the simulated change and the change in the eye tissue to be achieved, the auxiliary control program applied in step b) is chosen as the control program to be generated, and e) when in step c) the comparison does not yield a sufficient agreement between the simulated change and the change in the eye tissue to be achieved, at least one of the treatment parameters in step b) is/are modified and steps b), c) and d) are then performed again therewith.
    • 用于控制电磁辐射源的控制程序,利用该控制程序,通过引入到组织中的光敏剂来实现患者的眼组织中的交联,以引起眼组织的变化 和/或其机械特性之一,控制程序已经通过以下步骤生产:a)获取参考患者和眼睛的测量数据,b)具有测量数据和处理参数,其涉及预定的辅助 用于控制电磁辐射源的控制程序,在计算机中模拟参考用这些处理参数获得的眼组织变化的结果,c)将以这种方式模拟的变化与眼组织的变化进行比较 d)当步骤c)在模拟变化和要实现的眼组织变化之间产生足够的一致性时,辅助控制器 选择在步骤b)中应用的ogram作为要产生的控制程序,以及e)当在步骤c)中,所述比较在所述模拟变化与要实现的眼组织的变化之间不能产生足够的一致性时,至少一个 的步骤b)中的处理参数被修改,然后再次执行步骤b),c)和d)。
    • 8. 发明申请
    • Method for Determining Control Information for Photorefractive Corneal Surgery and Method for Providing Correction Information Required Therefor
    • 确定光折射角膜手术控制信息的方法及其所需修正信息的方法
    • US20100292677A1
    • 2010-11-18
    • US12063754
    • 2006-08-18
    • Michael MrochenMichael Büeler
    • Michael MrochenMichael Büeler
    • A61F9/01
    • A61F9/008A61F9/00804A61F2009/00848A61F2009/00872
    • A method for determining control information for controlling laser radiation irradiated onto the cornea of an eye to be treated photorefractively comprises correcting a corneal ablation profile, obtained by measuring optical properties of the eye, with the aid of correction information, the control information being formed on the basis of the corrected ablation profile thus produced. According to the invention, the correction of the ablation profile is performed in the spatial frequency domain. To this end, the ablation profile is transformed into a spatial frequency spectrum. Corrected amplitude or/and phase values are then determined for various discrete spectral components of the ablation profile on the basis of stored amplitude or/and phase correction information. Subsequently, the spatial frequency spectrum with the amplitude or/and phase corrected spectral components is backtransformed into the geometric spatial domain. The result is the corrected ablation profile. The amplitude and phase correction information in this case respectively represent for a number of spatial frequencies differing at least by the frequency value a predetermined relationship between values of the amplitude or/and phase at the relevant spatial frequency and corrected amplitude or/and phase values at this spatial frequency.
    • 一种用于确定用于控制照射到待处理的眼睛的角膜上的激光辐射的控制信息的方法,其特征在于,包括:通过校正信息校正通过测量眼睛的光学特性所获得的角膜消融轮廓,所述控制信息形成于 由此产生的校正消融轮廓的基础。 根据本发明,在空间频域中执行消融轮廓的校正。 为此,将消融轮廓变换为空间频谱。 然后基于存储的幅度或/和相位校正信息,确定消融轮廓的各种离散频谱分量的校正幅度或/和相位值。 随后,具有振幅或/和相位校正的光谱分量的空间频谱被逆转换为几何空间域。 结果是校正的消融轮廓。 在这种情况下,幅度和相位校正信息分别表示对于空间频率的数量至少不同的频率值,相关空间频率处的振幅或/和相位的值之间的预定关系以及校正的幅度或/和相位值 这个空间频率。