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1. 发明授权

US5667486A Prostatic stent 失效
标题翻译：前列腺支架
公开(公告)号：US5667486A
公开(公告)日：1997-09-16
申请号：US233660
申请日：1994-04-26
申请人： Michael A. Mikulich , Claude O. Clerc , Michael R. Jedwab , Adrian Furrer , Alain Mariller , John H. Burton , Claude Tihon
发明人： Michael A. Mikulich , Claude O. Clerc , Michael R. Jedwab , Adrian Furrer , Alain Mariller , John H. Burton , Claude Tihon
IPC分类号： A61F2/04 , A61F2/90 , A61M5/00 , A61F2/06
CPC分类号： A61F2/90 , A61F2/04 , A61F2230/0008
摘要： A prostatic stent and method of manufacture. The stent has an elongate body defining a passage therethrough and includes a distal section, a mid-section and a proximal section. The elongate body has a length sufficient to extend distally from a bladder neck to a position somewhat short of the external sphincter. The proximal section has a shape conforming to the neck of the urinary bladder.
摘要翻译：前列腺支架及其制造方法。支架具有限定穿过其中的通道的细长主体，并且包括远侧部分，中间部分和近端部分。细长体的长度足以从膀胱颈向远端延伸到略短于外括约肌的位置。近端部分具有符合膀胱颈部的形状。

2. 发明授权

US5356423A Resectable self-expanding stent 失效
标题翻译：可扩展自扩张支架
公开(公告)号：US5356423A
公开(公告)日：1994-10-18
申请号：US53846
申请日：1993-04-22
申请人： Claude Tihon , John H. Burton , Bradford G. Staehle , Michael A. Mikulich
发明人： Claude Tihon , John H. Burton , Bradford G. Staehle , Michael A. Mikulich
IPC分类号： A61F2/90 , A61M29/00 , A61F2/06
CPC分类号： A61F2/90 , A61F2220/0016
摘要： A stent for transluminal implantation comprising a single-piece tubular member having a fenestrated side wall exhibiting a pattern of uniformly spaced openings defined by intersecting strands where the strands are integrally joined together at their points of intersection whereby the tubular member can be radially compressed from a larger diameter to a smaller diameter by the application of a uniform inwardly directed radial force and which self-expands to a larger diameter when the radial compressive force is removed. The compression and subsequent self-expansion occurs without an appreciable change in the stent's length. By forming the stent from a thermoplastic material, it may later be resected by carving it up into small pieces preferably using an electrosurgical instrument.
摘要翻译：一种用于腔内植入的支架，其包括具有开窗侧壁的单件式管状构件，其具有由交叉股线限定的均匀间隔开口的图案，其中股线在其交叉点处一体地接合在一起，从而管状构件可从通过施加均匀的向内定向的径向力将较大的直径扩大到更小的直径，并且当径向压缩力被移除时，其自身膨胀到更大的直径。压缩和随后的自膨胀在支架长度没有明显变化的情况下发生。通过从热塑性材料形成支架，可以稍后将其切割成小块，最好使用电外科器械切割。

3. 发明授权

US4938760A Female suspension procedure 失效
标题翻译：女性暂停手术
公开(公告)号：US4938760A
公开(公告)日：1990-07-03
申请号：US330390
申请日：1989-03-29
申请人： John H. Burton , Reginald C. Bruskewitz , Michael A. Mikulich , William D. Saville
发明人： John H. Burton , Reginald C. Bruskewitz , Michael A. Mikulich , William D. Saville
IPC分类号： A61B17/00 , A61B17/04 , A61F2/00
CPC分类号： A61B17/0401 , A61F2/0036 , A61B2017/00805 , A61B2017/0404 , A61B2017/0443 , A61B2017/0453 , Y10S128/25
摘要： A method for suspending the urethrovesical junction in females comprises inserting sutures through a puncture or incision in the suprapubic abdominal area or through a puncture or incision in the vaginal wall, suspending the urethrovesical junction with the sutures, and anchoring the sutures with an anchoring means at an anchoring site. The anchoring means is a relatively rigid helix having an attaching means to attach the suture, or a pad adapted to be delivered with a delivery means to the anchoring site, or a flip anchor in substantial axial alignment with a placement means and adapted to be flipped from the axial alignment to an angled position, or an adjustable tissue anchor having a means for adjustably attaching the sutures.

4. 发明授权

US4651721A Penile prosthesis system 失效
标题翻译：阴茎假体系统
公开(公告)号：US4651721A
公开(公告)日：1987-03-24
申请号：US722123
申请日：1985-04-10
申请人： Michael A. Mikulich , John H. Burton , Christopher H. Porter
发明人： Michael A. Mikulich , John H. Burton , Christopher H. Porter
IPC分类号： A61F2/26
CPC分类号： A61F2/26
摘要： A penile prosthesis system involves the use of an inflatable penile prosthesis which is expandable under pressurization from a flaccid to an erect state. The prosthesis exhibits a low modulus of elasticity in expansion but ultimately reaches a modulus transition after which it exhibits a high modulus of elasticity and resists further expansion. The prosthesis may also be formed of a material which elastically expands from a flaccid to an erect state and elastically contracts thereafter. In its erect state the prosthesis is taut and the surrounding tissue may be similarly taut and pressurized because of the expansion of the prosthesis in girth. If a weakening occurs in the surrounding tissue, the tendancy to form localized penile bulges is limited because of the inability of the prostheis to expand readily beyond its modulus transition.
摘要翻译：阴茎假体系统涉及使用可膨胀的阴茎假体，其在从松弛状态到直立状态的加压下可膨胀。假体在膨胀中表现出低的弹性模量，但是最终达到模量转变，之后其显示出高的弹性模量并且抵抗进一步的膨胀。假体也可以由弹性膨胀从松弛状态到直立状态的材料形成，然后弹性收缩。在其直立状态下，由于假体在周长中的膨胀，假体被拉紧并且周围的组织可以类似地拉紧和加压。如果在周围组织中发生弱化，则形成局部阴茎隆起的倾向是有限的，因为假肢不能容易地膨胀超过其模量转变。

5. 发明授权

US4392562A Limited bend malleable penile prosthesis 失效
标题翻译：有限弯曲可塑性阴茎假体
公开(公告)号：US4392562A
公开(公告)日：1983-07-12
申请号：US275288
申请日：1981-06-19
申请人： John H. Burton , Michael A. Mikulich
发明人： John H. Burton , Michael A. Mikulich
IPC分类号： A61F2/26 , A61F5/00
CPC分类号： A61F2/26
摘要： A prosthesis adapted to be implanted in a penis includes an elongate malleable element which may be bent to enable the prosthesis to be conformed to a variety of shapes. A bend-limiting member is positioned next to the malleable element and serves to limit the radius of bend of the malleable element and thereby minimize damage or weakening to the malleable element through extreme bending. The malleable element and the bend-limiting member are encased within a physiologically inert plastic body.
摘要翻译：适于植入阴茎的假体包括细长的延展性元件，其可被弯曲以使假体能够符合各种形状。弯曲限制构件定位在可延展元件的旁边，并用于限制可延展元件的弯曲半径，从而通过极限弯曲使对延展性元件的损伤或弱化最小化。可塑性元件和弯曲限制构件被包裹在生理惰性塑料体内。

6. 发明授权

US4267829A Penile prosthesis 失效
标题翻译：阴茎假体
公开(公告)号：US4267829A
公开(公告)日：1981-05-19
申请号：US108124
申请日：1979-12-28
申请人： John H. Burton , Michael A. Mikulich
发明人： John H. Burton , Michael A. Mikulich
IPC分类号： A61F2/26 , A61F5/00
CPC分类号： A61F2/26
摘要： This implantable penile prosthesis may be surgically implanted in human males to cure erectile impotence. The prosthesis includes a pair of rigid portions joined by a hollow tubular section, all of which are implanted inside and along the length of a penis. The tubular section is connected to a pump means which controls erection of the penis by controlling the supply of fluid pressure to the tubular section. The tubular section includes a chamber means which undergoes only a small change in volume and therefore requires minimal fluid displacement as the prosthesis goes between a nonerect and an erect condition.
摘要翻译：这种可植入的阴茎假体可以手术植入人类雄性以治愈勃起阳。。假体包括通过中空管状部分连接的一对刚性部分，所有这些刚性部分植入在阴茎的内部并沿着阴茎的长度。管状部分连接到泵装置，其通过控制对管状部分的流体压力的供应来控制勃起阴茎。管状部分包括腔体装置，该腔室装置仅体积小的变化，因此假体在非直立状态和直立状态之间需要最小的流体位移。

7. 发明授权

US5078720A Stent placement instrument and method 失效
标题翻译：支架放置仪和方法
公开(公告)号：US5078720A
公开(公告)日：1992-01-07
申请号：US518064
申请日：1990-05-02
申请人： John H. Burton , Michael A. Mikulich
发明人： John H. Burton , Michael A. Mikulich
IPC分类号： A61F2/06 , A61F2/84
CPC分类号： A61F2/95 , A61F2002/9517
摘要： An instrument for the placement of a self-expanding stent in a body canal, which comprises an elongated inner tube having an outer tube disposed along its axis adapted to carry and retain a self-expanding stent adjacent its proximal end, and an arrangement for releasing the stent, in combination with at least one of the following components: (a) a location member for positioning and fixing the instrument so that the stent is released at a desired location in the body canal, and (b) a member for releasing the stent in a retrograde manner. A method for placing a self-expanding stent in a body canal is also disclosed.
摘要翻译：一种用于将自扩张支架放置在体管中的仪器，其包括细长的内管，该内管具有沿其轴线设置的外管，其适于携带和保持邻近其近端的自扩张支架，以及用于释放的装置所述支架与以下组件中的至少一个组合：（a）用于定位和固定所述器械的定位构件，使得所述支架在体管中的期望位置处被释放，以及（b）用于释放所述支架的构件支架以逆行方式。还公开了将自扩张支架置于体管中的方法。

8. 发明授权

US5499994A Dilation device for the urethra 失效
标题翻译：尿道扩张装置
公开(公告)号：US5499994A
公开(公告)日：1996-03-19
申请号：US234196
申请日：1994-04-28
申请人： Claude Tihon , John H. Burton , Timothy C. Cook , David Rhum
发明人： Claude Tihon , John H. Burton , Timothy C. Cook , David Rhum
IPC分类号： A61F2/94 , A61F7/12 , A61M29/00 , A61M29/04 , A61F2/04 , A61M5/00
CPC分类号： A61F2/94 , A61M29/02 , A61F2220/0008
摘要： A device for dilating at least an obstructed portion of a urethra includes a hollow core member with opposed open ends permitting urination therethrough from the bladder, a confining covering disposed on the hollow member having a length of at least that of the obstructed portion and having hydrophilic means integrally associated therewith. The hydrophilic means is capable of absorbing water and gradually expanding for at least 30 minutes whereby the outer surface of the confining covering expands radially and outwardly, after insertion into the urethra, until dilation of the obstructed portion occurs to a desired diameter and configuration. Methods for dilating an obstructed portion of the urethra and for treating benign prostatic hyperplasia are also provided.
摘要翻译：用于扩张尿道的至少阻塞部分的装置包括具有相对的开口端的中空芯构件，其允许从膀胱穿过其中的尿布，设置在中空构件上的限制覆盖物，其长度至少为阻塞部分的长度并具有亲水性与其整体相关联的装置。亲水装置能够吸收水并逐渐膨胀至少30分钟，由此限制覆盖物的外表面在插入尿道之后径向和向外扩张，直到阻塞部分的扩张发生到期望的直径和构型。还提供了扩张尿道阻塞部分和治疗良性前列腺增生的方法。

9. 发明授权

US5496271A Combined hyperthermia and dilation catheter 失效
标题翻译：联合热疗和扩张导管
公开(公告)号：US5496271A
公开(公告)日：1996-03-05
申请号：US78367
申请日：1993-06-16
申请人： John H. Burton , Timothy C. Cook , Claude Tihon
发明人： John H. Burton , Timothy C. Cook , Claude Tihon
IPC分类号： A61M25/00 , A61B17/00 , A61B18/18 , A61F2/958 , A61F7/12 , A61M29/02 , A61N5/04 , A61H31/00
CPC分类号： A61M25/1011 , A61B18/18 , A61B18/1815 , A61F7/123 , A61B2017/00274 , A61B2018/00166 , A61B2018/00547 , A61B2018/1861 , A61M2025/1084 , A61M29/02
摘要： An apparatus and method for treatment of conditions in which it is desired to simultaneously hyperthermally treat diseased target tissue in a patient and dilate a lumen of a patient which is compressed and/or obstructed by the diseased target tissue and/or surrounding tissue is disclosed. The apparatus generally includes a catheter for insertion into a lumen of the patient, such as in the prostatic urethra; an antenna for applying microwave or radio frequency energy to the selected target tissue to produce hyperthermal effects therein, thereby causing therapeutic alteration of the selected target tissue cells; a dilation balloon for simultaneously dilating the lumen of the patient and for compressing tissue to restrict blood flow to said tissue, thereby reducing the heat sink effect of blood-supplied tissue absorbing heat energy applied thereto, enabling both greater uniformity of heating in selected target diseased tissue and a reduction in the amount of power required to supply an effective level of energy to the selected target diseased tissue; and a fixation balloon for securing the apparatus during treatment. The apparatus and method are particularly adapted to the treatment of diseases of the prostate, such as benign prostatic hypertrophy (BPH), prostatitis and prostatic cancer, as well as in the treatment of certain tumors of the esophagus and the gastro-intestinal tract.
摘要翻译：公开了一种用于治疗其中期望同时热疗治疗患者中的患病目标组织并扩张病变靶组织和/或周围组织被压缩和/或阻塞的患者的内腔的病症的装置和方法。该装置通常包括用于插入到患者的内腔中的导管，例如在前列腺尿道中; 用于将微波或射频能量施加到所选择的目标组织以在其中产生超热效应的天线，从而引起所选择的靶组织细胞的治疗性改变; 扩张气囊，用于同时扩张患者的内腔并压缩组织以限制血液流向所述组织，从而减少供血组织吸收施加到其上的热能的散热效应，使得所选靶病变中的加热均匀性更高组织和减少向选定的目标患病组织提供有效水平的能量所需的功率量; 以及用于在处理期间固定设备的固定气球。该装置和方法特别适用于治疗前列腺疾病，例如良性前列腺肥大（BPH），前列腺炎和前列腺癌，以及治疗食管和胃肠道的某些肿瘤。

10. 发明授权

US5335669A Rectal probe with temperature sensor 失效
标题翻译：直径探头带温度传感器
公开(公告)号：US5335669A
公开(公告)日：1994-08-09
申请号：US50922
申请日：1993-04-21
申请人： Claude Tihon , Timothy C. Cook , John H. Burton , Ronald Svejkovsky
发明人： Claude Tihon , Timothy C. Cook , John H. Burton , Ronald Svejkovsky
IPC分类号： A61F7/12 , A61B5/00 , A61B5/01 , A61B17/00 , A61F2/958
CPC分类号： A61B5/01 , A61B5/6853 , A61M25/1011 , A61B2017/00274 , A61B2018/00547
摘要： A rectal probe comprising a catheter having a longitudinal axis around which is mounted an inflatable, low pressure, compliant balloon having a temperature element associated with the wall thereof, means for holding the probe at a proper position within a patient's rectum and means for inflating the balloon when it is properly positioned to put the temperature element in intimate contact with the anterior side of the rectum. A method for monitoring a patient's rectal mucosal temperature during thermal treatment of the patient's prostate is also disclosed.
摘要翻译：直肠探针，其包括具有纵向轴线的导管，围绕该导管安装有具有与其壁相关联的温度元件的可膨胀的低压柔顺气囊，用于将探针保持在患者直肠内的适当位置的装置，当适当定位以使温度元件与直肠的前侧紧密接触时，气囊。还公开了一种用于在患者前列腺的热治疗期间监测患者的直肠粘膜温度的方法。

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