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1. 发明授权

US5335669A Rectal probe with temperature sensor 失效
标题翻译：直径探头带温度传感器
公开(公告)号：US5335669A
公开(公告)日：1994-08-09
申请号：US50922
申请日：1993-04-21
申请人： Claude Tihon , Timothy C. Cook , John H. Burton , Ronald Svejkovsky
发明人： Claude Tihon , Timothy C. Cook , John H. Burton , Ronald Svejkovsky
IPC分类号： A61F7/12 , A61B5/00 , A61B5/01 , A61B17/00 , A61F2/958
CPC分类号： A61B5/01 , A61B5/6853 , A61M25/1011 , A61B2017/00274 , A61B2018/00547
摘要： A rectal probe comprising a catheter having a longitudinal axis around which is mounted an inflatable, low pressure, compliant balloon having a temperature element associated with the wall thereof, means for holding the probe at a proper position within a patient's rectum and means for inflating the balloon when it is properly positioned to put the temperature element in intimate contact with the anterior side of the rectum. A method for monitoring a patient's rectal mucosal temperature during thermal treatment of the patient's prostate is also disclosed.
摘要翻译：直肠探针，其包括具有纵向轴线的导管，围绕该导管安装有具有与其壁相关联的温度元件的可膨胀的低压柔顺气囊，用于将探针保持在患者直肠内的适当位置的装置，当适当定位以使温度元件与直肠的前侧紧密接触时，气囊。还公开了一种用于在患者前列腺的热治疗期间监测患者的直肠粘膜温度的方法。

2. 发明授权

US5499994A Dilation device for the urethra 失效
标题翻译：尿道扩张装置
公开(公告)号：US5499994A
公开(公告)日：1996-03-19
申请号：US234196
申请日：1994-04-28
申请人： Claude Tihon , John H. Burton , Timothy C. Cook , David Rhum
发明人： Claude Tihon , John H. Burton , Timothy C. Cook , David Rhum
IPC分类号： A61F2/94 , A61F7/12 , A61M29/00 , A61M29/04 , A61F2/04 , A61M5/00
CPC分类号： A61F2/94 , A61M29/02 , A61F2220/0008
摘要： A device for dilating at least an obstructed portion of a urethra includes a hollow core member with opposed open ends permitting urination therethrough from the bladder, a confining covering disposed on the hollow member having a length of at least that of the obstructed portion and having hydrophilic means integrally associated therewith. The hydrophilic means is capable of absorbing water and gradually expanding for at least 30 minutes whereby the outer surface of the confining covering expands radially and outwardly, after insertion into the urethra, until dilation of the obstructed portion occurs to a desired diameter and configuration. Methods for dilating an obstructed portion of the urethra and for treating benign prostatic hyperplasia are also provided.
摘要翻译：用于扩张尿道的至少阻塞部分的装置包括具有相对的开口端的中空芯构件，其允许从膀胱穿过其中的尿布，设置在中空构件上的限制覆盖物，其长度至少为阻塞部分的长度并具有亲水性与其整体相关联的装置。亲水装置能够吸收水并逐渐膨胀至少30分钟，由此限制覆盖物的外表面在插入尿道之后径向和向外扩张，直到阻塞部分的扩张发生到期望的直径和构型。还提供了扩张尿道阻塞部分和治疗良性前列腺增生的方法。

3. 发明授权

US5496271A Combined hyperthermia and dilation catheter 失效
标题翻译：联合热疗和扩张导管
公开(公告)号：US5496271A
公开(公告)日：1996-03-05
申请号：US78367
申请日：1993-06-16
申请人： John H. Burton , Timothy C. Cook , Claude Tihon
发明人： John H. Burton , Timothy C. Cook , Claude Tihon
IPC分类号： A61M25/00 , A61B17/00 , A61B18/18 , A61F2/958 , A61F7/12 , A61M29/02 , A61N5/04 , A61H31/00
CPC分类号： A61M25/1011 , A61B18/18 , A61B18/1815 , A61F7/123 , A61B2017/00274 , A61B2018/00166 , A61B2018/00547 , A61B2018/1861 , A61M2025/1084 , A61M29/02
摘要： An apparatus and method for treatment of conditions in which it is desired to simultaneously hyperthermally treat diseased target tissue in a patient and dilate a lumen of a patient which is compressed and/or obstructed by the diseased target tissue and/or surrounding tissue is disclosed. The apparatus generally includes a catheter for insertion into a lumen of the patient, such as in the prostatic urethra; an antenna for applying microwave or radio frequency energy to the selected target tissue to produce hyperthermal effects therein, thereby causing therapeutic alteration of the selected target tissue cells; a dilation balloon for simultaneously dilating the lumen of the patient and for compressing tissue to restrict blood flow to said tissue, thereby reducing the heat sink effect of blood-supplied tissue absorbing heat energy applied thereto, enabling both greater uniformity of heating in selected target diseased tissue and a reduction in the amount of power required to supply an effective level of energy to the selected target diseased tissue; and a fixation balloon for securing the apparatus during treatment. The apparatus and method are particularly adapted to the treatment of diseases of the prostate, such as benign prostatic hypertrophy (BPH), prostatitis and prostatic cancer, as well as in the treatment of certain tumors of the esophagus and the gastro-intestinal tract.
摘要翻译：公开了一种用于治疗其中期望同时热疗治疗患者中的患病目标组织并扩张病变靶组织和/或周围组织被压缩和/或阻塞的患者的内腔的病症的装置和方法。该装置通常包括用于插入到患者的内腔中的导管，例如在前列腺尿道中; 用于将微波或射频能量施加到所选择的目标组织以在其中产生超热效应的天线，从而引起所选择的靶组织细胞的治疗性改变; 扩张气囊，用于同时扩张患者的内腔并压缩组织以限制血液流向所述组织，从而减少供血组织吸收施加到其上的热能的散热效应，使得所选靶病变中的加热均匀性更高组织和减少向选定的目标患病组织提供有效水平的能量所需的功率量; 以及用于在处理期间固定设备的固定气球。该装置和方法特别适用于治疗前列腺疾病，例如良性前列腺肥大（BPH），前列腺炎和前列腺癌，以及治疗食管和胃肠道的某些肿瘤。

4. 发明授权

US5667486A Prostatic stent 失效
标题翻译：前列腺支架
公开(公告)号：US5667486A
公开(公告)日：1997-09-16
申请号：US233660
申请日：1994-04-26
申请人： Michael A. Mikulich , Claude O. Clerc , Michael R. Jedwab , Adrian Furrer , Alain Mariller , John H. Burton , Claude Tihon
发明人： Michael A. Mikulich , Claude O. Clerc , Michael R. Jedwab , Adrian Furrer , Alain Mariller , John H. Burton , Claude Tihon
IPC分类号： A61F2/04 , A61F2/90 , A61M5/00 , A61F2/06
CPC分类号： A61F2/90 , A61F2/04 , A61F2230/0008
摘要： A prostatic stent and method of manufacture. The stent has an elongate body defining a passage therethrough and includes a distal section, a mid-section and a proximal section. The elongate body has a length sufficient to extend distally from a bladder neck to a position somewhat short of the external sphincter. The proximal section has a shape conforming to the neck of the urinary bladder.
摘要翻译：前列腺支架及其制造方法。支架具有限定穿过其中的通道的细长主体，并且包括远侧部分，中间部分和近端部分。细长体的长度足以从膀胱颈向远端延伸到略短于外括约肌的位置。近端部分具有符合膀胱颈部的形状。

5. 发明授权

US5356423A Resectable self-expanding stent 失效
标题翻译：可扩展自扩张支架
公开(公告)号：US5356423A
公开(公告)日：1994-10-18
申请号：US53846
申请日：1993-04-22
申请人： Claude Tihon , John H. Burton , Bradford G. Staehle , Michael A. Mikulich
发明人： Claude Tihon , John H. Burton , Bradford G. Staehle , Michael A. Mikulich
IPC分类号： A61F2/90 , A61M29/00 , A61F2/06
CPC分类号： A61F2/90 , A61F2220/0016
摘要： A stent for transluminal implantation comprising a single-piece tubular member having a fenestrated side wall exhibiting a pattern of uniformly spaced openings defined by intersecting strands where the strands are integrally joined together at their points of intersection whereby the tubular member can be radially compressed from a larger diameter to a smaller diameter by the application of a uniform inwardly directed radial force and which self-expands to a larger diameter when the radial compressive force is removed. The compression and subsequent self-expansion occurs without an appreciable change in the stent's length. By forming the stent from a thermoplastic material, it may later be resected by carving it up into small pieces preferably using an electrosurgical instrument.
摘要翻译：一种用于腔内植入的支架，其包括具有开窗侧壁的单件式管状构件，其具有由交叉股线限定的均匀间隔开口的图案，其中股线在其交叉点处一体地接合在一起，从而管状构件可从通过施加均匀的向内定向的径向力将较大的直径扩大到更小的直径，并且当径向压缩力被移除时，其自身膨胀到更大的直径。压缩和随后的自膨胀在支架长度没有明显变化的情况下发生。通过从热塑性材料形成支架，可以稍后将其切割成小块，最好使用电外科器械切割。

6. 发明申请

US20120029269A1 APPARATUS AND METHOD FOR INSERTING AN ADJUSTABLE IMPLANTABLE GENITOURINARY DEVICE 审中-公开
标题翻译：用于插入可调节可植入式设备的装置和方法
公开(公告)号：US20120029269A1
公开(公告)日：2012-02-02
申请号：US13080350
申请日：2011-04-05
申请人： John H. Burton , Timothy C. Cook
发明人： John H. Burton , Timothy C. Cook
IPC分类号： A61F2/02
CPC分类号： A61F2/0027 , A61F2/004 , Y10S128/25
摘要： An implantable medical device and method for adjustably restricting a selected body lumen such as a urethra or ureter of a patient to treat urinary incontinence or ureteral reflux. The device includes an adjustable element that includes a chamber and a hydrophilic material substantially encapsulated in the chamber to expand the adjustable element by absorbing fluid entering the chamber.
摘要翻译：一种可植入医疗装置和方法，用于可调节地限制患者的选定体腔，例如尿道或输尿管，以治疗尿失禁或输尿管反流。该装置包括可调元件，其包括腔室和基本上封装在腔室中的亲水材料，以通过吸收进入腔室的流体来膨胀可调节元件。

7. 发明申请

US20110124957A1 APPARATUS AND METHOD FOR INSERTING AN ADJUSTABLE IMPLANTABLE GENITOURINARY DEVICE 审中-公开
标题翻译：用于插入可调节可植入式设备的装置和方法
公开(公告)号：US20110124957A1
公开(公告)日：2011-05-26
申请号：US12838927
申请日：2010-07-19
申请人： John H. Burton , Richard A. Noddin , Dale L. Schreiner , Timothy C. Cook
发明人： John H. Burton , Richard A. Noddin , Dale L. Schreiner , Timothy C. Cook
IPC分类号： A61F2/02
CPC分类号： A61F2/0027 , A61F2/004 , Y10S128/25
摘要： An implantable medical device and method for adjustably restricting a selected body lumen such as a urethra or ureter of a patient to treat urinary incontinence or ureteral reflux. The device includes an adjustable element and a tubular elongate body, where the adjustable element includes a chamber and the tubular elongate body includes at least a first interior passageway which extends longitudinally in the tubular elongate body from a first opening at the proximal end to a second opening in fluid communication with the chamber. Fluid volume passed through the first passageway is used for adjustably expanding or contracting the adjustable element. The implantable medical device further includes a sheath and a sleeve, where the sheath includes a wall having an inner surface which defines a channel through which at least a portion of the implantable device and the sleeve can pass. Alternatively, the implantable medical device includes a tip suitable to penetrate tissue so that the implantable medical device can be implanted within the tissue of a patient.
摘要翻译：一种可植入医疗装置和方法，用于可调节地限制患者的选定体腔，例如尿道或输尿管，以治疗尿失禁或输尿管反流。该装置包括可调元件和管状细长主体，其中可调节元件包括腔室，并且管状细长主体包括至少第一内部通道，该第一内部通道在管状细长主体中从近端的第一开口纵向延伸至第二内部通道打开与腔室流体连通。通过第一通道的流体体积用于可调整地扩张或收缩可调元件。可植入医疗装置还包括护套和套管，其中护套包括具有限定通道的内壁的壁，至少一部分可植入装置和套管可穿过该通道。或者，可植入医疗装置包括适于穿透组织的尖端，使得可植入的医疗装置可以植入患者的组织内。

8. 发明申请

US20100168788A1 IMPLANTATION TOOL FOR ADJUSTABLE IMPLANTABLE GENITOURINARY DEVICE 审中-公开
标题翻译：可植入的植入式植入物植入物
公开(公告)号：US20100168788A1
公开(公告)日：2010-07-01
申请号：US12720786
申请日：2010-03-10
申请人： Dale L. Schreiner , James E. Cabak , Michael R. Satteson , John H. Burton , Timothy C. Cook
发明人： Dale L. Schreiner , James E. Cabak , Michael R. Satteson , John H. Burton , Timothy C. Cook
IPC分类号： A61B17/28
CPC分类号： A61B17/29 , A61B17/0218 , A61B17/295 , A61B17/320016 , A61B17/3417 , A61B17/3468 , A61B2017/0046 , A61B2017/00477 , A61B2017/2926 , A61B2017/320044 , A61B2017/346 , A61B2090/062 , A61F2/004
摘要： The present application includes a system for the preparation of a patient for the implantation of post-operatively adjustable coaptation device. For example, the present subject matter includes a tool having a proximal portion and a distal portion, and an elongate section disposed between the proximal portion and the distal portion. The tool additionally includes jaws hinged at a first joint, the first joint located at the distal portion of the tool, the jaws adapted to vary between an open state and a closed state, the closed state defining a blunt tip. Also, the tool includes a handle located at the proximal portion of the tool. The handle and the jaws are connected so that motion of the handle moves the jaws from the closed state to the open state.
摘要翻译：本申请包括用于准备用于植入术后可调节接合装置的患者的系统。例如，本主题包括具有近端部分和远端部分的工具，以及设置在近端部分和远端部分之间的细长部分。该工具还包括铰链在第一关节处的第一关节，位于工具的远端部分处的第一关节，适于在打开状态和关闭状态之间变化的夹爪，闭合状态限定钝头。此外，该工具包括位于工具的近端部分处的手柄。手柄和夹爪连接，使得手柄的运动将钳口从关闭状态移动到打开状态。

9. 发明申请

US20080167518A1 METHOD AND APPARATUS FOR ADJUSTABLE SLING FOR TREATMENT OF URINARY STRESS INCONTINENCE 审中-公开
标题翻译：用于治疗尿路压力不调的可调节的方法和装置
公开(公告)号：US20080167518A1
公开(公告)日：2008-07-10
申请号：US12054662
申请日：2008-03-25
申请人： John H. Burton , Timothy C. Cook
发明人： John H. Burton , Timothy C. Cook
IPC分类号： A61F2/02
CPC分类号： A61F2/0045 , A61F2/004 , A61F2250/0003
摘要： One embodiment of the present subject matter includes an implantable, adjustable sling for a body which includes an implantable sling cup connected to a first strap and a second strap, the first strap and the second strap adapted to be anchored within the body and at least one adjustable element forming an integral portion of the first strap.
摘要翻译：本主题的一个实施例包括用于身体的可植入的可调节吊带，其包括连接到第一带和第二带的可植入吊带杯，所述第一带和所述第二带适于锚定在所述主体内，并且至少一个可调元件形成第一带的整体部分。

10. 发明授权

US07364540B1 Implantable device and method for adjustably restricting a body lumen 失效
标题翻译：用于可调节地限制体腔的植入装置和方法
公开(公告)号：US07364540B1
公开(公告)日：2008-04-29
申请号：US09477977
申请日：2000-01-05
申请人： John H. Burton , Timothy C. Cook
发明人： John H. Burton , Timothy C. Cook
IPC分类号： A61F2/02
CPC分类号： A61B17/12 , A61B17/12013 , A61B2017/00539 , A61B2017/00557 , A61B2017/22051 , A61B2017/22062 , A61B2017/22067 , Y10S128/25
摘要： An implantable device and method for adjustably restricting a selected body lumen such as the urethra of a patient to treat urinary incontinence. The device includes an expandable element or membrane such as a balloon attached pressure-tightly to a flexible conduit at its forward end and includes a rear port portion containing an elastic septum and flow connected to the expandable element by a first passageway. The conduit contains a second passageway which allows it to be slid along an elongated guide probe initially inserted surgically into a patient's body adjacent the body lumen which is to be adjustably restricted. A suitable flowable material is injected from a syringe source into the device rear port sufficient to expand the membrane element and restrict the body lumen to the desired degree. The syringe and guide probe are removed and the skin incision is closed over the rear port end of the implanted device. The rear port septum is located under but near the patient's skin so that if it becomes necessary to post-operatively increase or decrease the degree of body lumen restriction it may be easily accessed with the needle of the syringe.
摘要翻译：一种用于可调节地限制所选择的体腔（例如患者的尿道）以治疗尿失禁的可植入装置和方法。该装置包括可膨胀元件或膜，例如在其前端处与柔性管道紧密连接的气囊，并且包括容纳弹性隔膜的后端口部分和通过第一通道连接到可膨胀元件的流体。导管包含第二通道，其允许其沿着最初插入手术的细长引导探针滑动到与可调节地限制的体腔相邻的患者体内。将合适的可流动材料从注射器源注入装置后端口中，足以使膜元件膨胀并将体腔限制到期望的程度。移除注射器和引导探针，并将皮肤切口封闭在植入装置的后端口端上。后端口隔膜位于患者皮肤附近，但靠近患者皮肤，因此如果需要在手术后增加或减少体腔限制的程度，则可以用注射器的针头轻松接近。

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