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1. 发明申请

US20130216518A1 COMPOSITION COMPRISING A COMBINATION OF AT LEAST ONE PROTEOLYTIC ENZYME AND AT LEAST ONE LIPOLYTIC ENZYME, FOR USE IN PREVENTING TRIGLYCERIDE SYNTHESIS 审中-公开
标题翻译：组合物包含至少一种蛋白酶和至少一种脂质体的组合，用于预防三羧酸合成
公开(公告)号：US20130216518A1
公开(公告)日：2013-08-22
申请号：US13519534
申请日：2011-10-28
申请人： Max Rombi
发明人： Max Rombi
IPC分类号： A61K38/48 , A61K38/46
CPC分类号： A61K38/482 , A61K38/465 , A61K2300/00
摘要： The present invention relates to a composition comprising a combination of at least one proteolytic enzyme, such as subtilisin, and at least one lipolytic enzyme, for use in preventing triglyceride synthesis, advantageously by degrading 2-monoacylglycerol in the intestine. The invention also has as an object such a composition for use as a drug, cosmetic agent, medical device, dietary composition, dietary supplement or nutraceutical, notably for use in preventing or treating obesity, atherosclerosis, type 2 diabetes or for use in preventing or reducing excess weight.
摘要翻译：本发明涉及包含至少一种蛋白水解酶（例如枯草杆菌蛋白酶）和至少一种脂解酶的组合的组合物，其用于预防甘油三酯合成，有利地通过降解肠中的2-单酰基甘油。本发明还具有用作药物，化妆剂，医疗装置，饮食组合物，膳食补充剂或营养品的组合物，特别是用于预防或治疗肥胖症，动脉粥样硬化，2型糖尿病或用于预防或治疗减少体重。

2. 发明授权

US06638545B1 Food complement and method for cosmetic treatment based on a grape extract rich in polyphenols 失效
标题翻译：基于富含多酚的葡萄提取物进行美容处理的食品补充剂和方法
公开(公告)号：US06638545B1
公开(公告)日：2003-10-28
申请号：US09936304
申请日：2001-11-26
申请人： Max Rombi
发明人： Max Rombi
IPC分类号： A61K3578
CPC分类号： A61K8/97 , A23L33/105 , A23V2002/00 , A61K8/347 , A61K2800/92 , A61Q19/06 , A23V2250/2132
摘要： The invention concerns firstly a food complement for dietetic and/or cosmetic purposes, containing anti-lipase properties, for oral administration. Said food complement is characterised in that it comprises a grape extract rich in or enriched with polyphenols.
摘要翻译：本发明首先涉及用于饮食和/或美容目的的含有抗脂肪酶性质的食品补充剂，用于口服给药。所述食品补充剂的特征在于其包含富含或富含多酚的葡萄提取物。

3. 发明授权

US4232023A Novel soluble derivatives of 2,4-diamino pyrimidine 失效
标题翻译： 2,4-二氨基嘧啶的新型可溶性衍生物
公开(公告)号：US4232023A
公开(公告)日：1980-11-04
申请号：US922845
申请日：1978-07-07
申请人： Pierre R. Dick , Max Rombi
发明人： Pierre R. Dick , Max Rombi
IPC分类号： C07D239/48 , C07D239/49 , C07H17/02 , A61K31/505
CPC分类号： C07D239/49 , C07H17/02
摘要： The novel derivatives correspond to the general formula II: ##STR1## in which: R.sub.1 R.sub.2 R.sub.3 and R.sub.4 represent identical or different groups which can each be a hydrogen or halogen atom or an alkyl group, alkoxy, or benzyloxy group and R is the residue of an R--CHO aldehyde selected from among linear or branched saturated aliphatic aldehydes including 1 to 4 carbon atoms or again represents the Z--CH.dbd.CH radical in which Z represents a hydrogen atom, a linear or branched saturated alkyl group, an aromatic nucleus or an aromatic heterocyclic nucleus or again R represents the radical HO CH.sub.2 (CH OH)n--in which n has the value of 3 or 4. The novel compounds have high solubility in water and antibacterial activity and potentiating power.
摘要翻译：新衍生物对应于通式II：其中：R 1 R 2 R 3和R 4表示可以各自为氢或卤素原子或烷基，烷氧基或苄氧基的相同或不同的基团，R 是选自包括1至4个碳原子的直链或支链饱和脂族醛中的R-CHO醛的残基，或再次代表Z-CH = CH基团，其中Z表示氢原子，直链或支链饱和烷基，芳香核或芳族杂环核，或者再次R代表基团HO CH 2（CH OH）n - ，其中n的值为3或4.新化合物在水中具有高溶解度和抗菌活性和增效能力。

4. 发明授权

US4150109A Devices for protecting animals from ectoparasites 失效
标题翻译：用于保护动物免受体外寄生虫的装置
公开(公告)号：US4150109A
公开(公告)日：1979-04-17
申请号：US857685
申请日：1977-12-05
申请人： Pierre R. Dick , Max Rombi
发明人： Pierre R. Dick , Max Rombi
IPC分类号： A01K27/00 , A01N25/34 , A01K29/00 , A01M1/20
CPC分类号： A01K27/007 , A01N25/34
摘要： Device for protecting animals from Ectoparasites comprising an active elementInsecticidal arrangement intended to be fastened to the neck of an animal, comprising an active element consisting of an active principle chosen from diazinone, diazoxone and the mixtures thereof, a solid macromolecular substance chosen from the vinyl and vinylidene substances, and a plasticizer, and an attachment member supporting said active member.
摘要翻译：用于保护动物免受包括活性成分的体外寄生虫的装置包含由活性成分组成的活性成分，所述活性成分由选自二嗪酮，二氮酮及其混合物的活性成分，选自乙烯基的固体大分子物质和亚乙烯基物质，以及增塑剂，以及支撑所述活性物质的附着构件。

5. 发明授权

US06830765B2 Green tea extract for treating obesity 有权
标题翻译：用于治疗肥胖症的绿茶提取物
公开(公告)号：US06830765B2
公开(公告)日：2004-12-14
申请号：US10274888
申请日：2002-10-22
申请人： Max Rombi
发明人： Max Rombi
IPC分类号： A61K3578
CPC分类号： A61K36/82 , A23F3/18 , A23F3/28 , A61K2300/00
摘要： The invention relates to a composition for the treatment of obesity, comprising a catechol-rich extract of green tea, in particular containing from 20% to 50% by mass of catechols expressed as epigallocatechol gallate (EGCG).
摘要翻译：本发明涉及一种用于治疗肥胖症的组合物，其包含富含儿茶酚的富茶提取物，特别是含有20％至50质量％的表没食子儿茶素没食子酸酯（EGCG）的邻苯二酚。

6. 发明授权

US06814986B1 Composition for treating obesity and esthetic treatment process 有权
标题翻译：用于治疗肥胖和美容治疗过程的组合物
公开(公告)号：US06814986B1
公开(公告)日：2004-11-09
申请号：US09601019
申请日：2000-10-17
申请人： Max Rombi
发明人： Max Rombi
IPC分类号： A61K3578
CPC分类号： A61K36/82 , A23F3/18 , A23F3/28 , A61K2300/00
摘要： The invention relates to a composition for the curative and prophylactic treatment of obesity, comprising a catechol-rich extract of green tea, in particular containing from 20% to 50% by mass of catechols expressed as epigallocatechol gallate (EGCG).

7. 发明授权

US06348609B1 Method for obtaining an oil that is rich in hydroxyoctadecadienoic fatty acids (HODE) or the esters thereof from a mixture containing linoleic acid or the esters thereof 失效
标题翻译：从含有亚油酸或其酯的混合物中获得富含羟基十八碳二烯酸脂肪酸（HODE）或其酯的油的方法
公开(公告)号：US06348609B1
公开(公告)日：2002-02-19
申请号：US09647474
申请日：2000-11-28
申请人： Max Rombi
发明人： Max Rombi
IPC分类号： C07C5100
CPC分类号： C11C3/006 , A23L33/115 , A61K8/02 , A61K8/365 , A61K8/37 , A61Q19/06
摘要： A method for obtaining an oil that is rich in hydroxyoctadecadienoic(HODE) fatty acids or the esters thereof. According to the inventive method, controlled oxidation of the linoleic acid and/or the linolenic acid or the esters thereof is performed in the presence of an oxidation catalyst. The oxidation is terminated when the HODE content or total ester content is more than 5 % and/or the 9-hydroxy-10,12-octadecadienoic(9-HODE) acid isomer or ester content is more than 1.5 % and reduction occurs for the hydroperoxides formed during the oxidation reaction by a reducer. The invention can be used as a medicament, food supplement or cosmetic.
摘要翻译：一种获得富含羟基十八碳二烯（HODE）脂肪酸的油或其酯的方法。根据本发明的方法，亚油酸和/或亚麻酸或其酯的受控氧化在氧化催化剂的存在下进行。当HODE含量或总酯含量大于5％和/或9-羟基-10,12-十八碳二烯酸（9-HODE）酸异构体或酯含量大于1.5％时，氧化终止，对于通过还原剂在氧化反应期间形成的氢过氧化物。本发明可以用作药物，食品补充剂或化妆品。

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