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1. 发明授权

US06398798B1 Catheter system for treating a vascular occlusion 失效
公开(公告)号：US06398798B1
公开(公告)日：2002-06-04
申请号：US09032773
申请日：1998-02-28
申请人： Matthew R. Selmon , Gerald Hansen , Charles Milo
发明人： Matthew R. Selmon , Gerald Hansen , Charles Milo
IPC分类号： A61B1722
摘要： A catherer system and method are provided including a blunt end assembly with a catheter and a blunt end member. The blunt end member includes jaw sections which have a first position or closed position for locating the blunt end member at the site of the occlusion within the native lumen of the blood vessel and a second position or open position wherein the jaw sections are able to press against the interior walls of the lumen adjacent the occlusion. The assembly includes an actuation member for moving the jaw sections from the closed to the open positions repeatedly resulting in a fracturing of the occlusion. A guide wire may be thread through an internal opening in the catheter and the blunt end member and after fracturing, across the occlusion.

2. 发明授权

US6120516A Method for treating vascular occlusion 失效
标题翻译：治疗血管闭塞的方法
公开(公告)号：US6120516A
公开(公告)日：2000-09-19
申请号：US32770
申请日：1998-02-28
申请人： Matthew R. Selmon , Gerald Hansen , Charles Milo
发明人： Matthew R. Selmon , Gerald Hansen , Charles Milo
IPC分类号： A61B17/22 , A61B17/28 , A61B19/00
CPC分类号： A61B17/29 , A61B1/00179 , A61B17/22 , A61B2017/22044 , A61B2017/22094 , A61B2090/306 , A61M2025/1047 , A61M25/0147
摘要： Disclosed herein is an intravascular catheter system for crossing a severe or total arterial occlusion; particularly, a steerable intravascular catheter providing a working element and the optical guidance thereof in crossing an occlusion. Also disclosed is a method of crossing a severe or total arterial occlusion with a steerable catheter working element under optical guidance.
摘要翻译：本文公开了用于穿过严重或全部动脉闭塞的血管内导管系统; 特别是提供工作元件的可导向的血管内导管及其在穿过闭塞时的光学引导。还公开了一种在光学引导下将严重或全部动脉闭塞与可导向的导管工作元件交叉的方法。

3. 发明授权

US06010449A Intravascular catheter system for treating a vascular occlusion 失效
标题翻译：用于治疗血管闭塞的血管内导管系统
公开(公告)号：US06010449A
公开(公告)日：2000-01-04
申请号：US808527
申请日：1997-02-28
申请人： Matthew R. Selmon , Gerald Hansen , Charles Milo
发明人： Matthew R. Selmon , Gerald Hansen , Charles Milo
IPC分类号： A61B5/00 , A61B17/00 , A61B17/22 , A61B17/32 , A61B18/24 , A61B19/00 , A61M1/00 , A61M29/00 , A61M29/02 , A61B1/005
CPC分类号： A61B5/0084 , A61B17/22 , A61B17/320725 , A61B18/245 , A61B2017/003 , A61B2017/22044 , A61B2017/22069 , A61B2017/320044 , A61B2090/3614 , A61B2217/005 , A61B5/0066 , A61M29/00 , A61M29/02
摘要： An intravascular catheter system for crossing a severe or total arterial occlusion includes a steerable intravascular catheter providing a working element and an optical guidance system. The optical guidance system is realized by an optical member with may include an imaging shaft that is rotated and measured by a motor/encoder assembly or which may include an optical switching device connected to a plurality of optical fibers. The working element may include a plurality of opening members that are actuated by an external plunger.
摘要翻译：用于穿过严重或全部动脉闭塞的血管内导管系统包括提供工作元件和光学引导系统的可操纵的血管内导管。光学引导系统由光学构件实现，该光学构件可以包括由电动机/编码器组件旋转和测量的成像轴，或者可以包括连接到多个光纤的光学开关装置。工作元件可以包括由外部柱塞致动的多个开启构件。

4. 发明授权

US5968064A Catheter system for treating a vascular occlusion 失效
标题翻译：用于治疗血管闭塞的导管系统
公开(公告)号：US5968064A
公开(公告)日：1999-10-19
申请号：US775264
申请日：1997-02-28
申请人： Matthew R. Selmon , Gerald Hansen , Charles Milo
发明人： Matthew R. Selmon , Gerald Hansen , Charles Milo
IPC分类号： A61B17/22 , A61B17/00 , A61B17/28 , A61B17/32 , A61F2/82 , A61M29/00 , A61M25/00
CPC分类号： A61M29/02 , A61B17/22031 , A61B2017/00845 , A61B2017/22069 , A61B2017/2933 , A61B2017/2937 , A61B2017/320044 , A61B2017/320741
摘要： Disclosed herein is a blunt end assembly including a catheter and a blunt end member. The blunt end member includes jaw sections which have a first closed position for locating the blunt end member at the site of the occlusion within the native lumen of the blood vessel and a second open position wherein the jaw sections are able to press against the interior walls of the lumen adjacent the occlusion. The assembly includes an actuation member for moving the jaw sections from the closed to the open positions repeatedly resulting in a fracturing of the occlusion. A guide wire may be thread through an internal opening in the catheter and the blunt end member and after fracturing, across the occlusion.
摘要翻译：本文公开了一种平头端组件，其包括导管和钝端构件。钝端构件包括钳口部分，其具有第一关闭位置，用于将钝端构件定位在血管的天然腔内的闭塞位置处，以及第二打开位置，其中钳口部分能够压靠内壁邻近闭塞的管腔。组件包括致动构件，用于将钳口部分从闭合位置重复地移动到打开位置，导致堵塞的压裂。引导线可以穿过导管内的内部开口和钝端部件，并且在压裂之后穿过闭塞。

5. 发明授权

US06800085B2 Methods and apparatus for treating vascular occlusions 有权
公开(公告)号：US06800085B2
公开(公告)日：2004-10-05
申请号：US09835043
申请日：2001-04-13
申请人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl , Gerald Hansen , E. Richard Hill, III
发明人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl , Gerald Hansen , E. Richard Hill, III
IPC分类号： A61M2900
CPC分类号： A61M29/02 , A61B17/22 , A61B17/22031 , A61B2017/00845 , A61B2017/22052 , A61B2017/22069 , A61B2017/22094 , A61B2017/2933 , A61B2017/2937 , A61B2017/320044 , A61B2017/320741
摘要： An intravascular catheter system for the treatment of occluded blood vessels that includes tissue displacement or hinged expansion members that are movable from a closed to an open position. An actuating assembly may be provided for moving the tissue expansion members between an open and closed position to exert a substantially lateral distal end force upon the region surrounding an occluded blood vessel. The tissue expansion members may stretch apart, tear or otherwise disrupt a vascular occlusion sufficiently to create a pathway that may support the passage or placement of a guidewire or an interventional vascular device across the occlusion or obstruction. Methods of crossing or displacing a vascular occlusion are further provided that include the positioning of a vascular catheter having at least one hinged spreading member positioned at the distal region of the catheter that is responsive to directed force along the longitudinal axis of the catheter. A directed force is applied to the actuator in order to deploy the spreading member and displace a vascular occlusion creating a path to permit the passage of a guidewire or device therethrough.

6. 发明授权

US06638247B1 Method and apparatus for treating vascular occlusions 有权
标题翻译：治疗血管闭塞的方法和装置
公开(公告)号：US06638247B1
公开(公告)日：2003-10-28
申请号：US09538441
申请日：2000-03-29
申请人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl , Gerald Hansen , E. Richard Hill, III
发明人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl , Gerald Hansen , E. Richard Hill, III
IPC分类号： A61M2900
CPC分类号： A61M29/02 , A61B17/22 , A61B17/22031 , A61B2017/00845 , A61B2017/22052 , A61B2017/22069 , A61B2017/22094 , A61B2017/2933 , A61B2017/2937 , A61B2017/320044 , A61B2017/320741
摘要： An intravascular catheter system for the treatment of occluded blood vessels that includes tissue displacement or hinged expansion members that are movable from a closed to an open position. An actuating assembly may be provided for moving the tissue expansion members between an open and closed position to exert a substantially lateral distal end force upon the region surrounding an occluded blood vessel. The tissue expansion members may stretch apart, tear or otherwise disrupt a vascular occlusion sufficiently to create a pathway that may support the passage or placement of a guidewire or an interventional vascular device across the occlusion or obstruction. Methods of crossing or displacing a vascular occlusion are further provided that include the positioning of a vascular catheter having at least one hinged spreading member positioned at the distal region of the catheter that is responsive to directed force along the longitudinal axis of the catheter. A directed force is applied to the actuator in order to deploy the spreading member and displace a vascular occlusion creating a path to permit the passage of a guidewire or device therethrough.
摘要翻译：一种用于治疗闭塞血管的血管内导管系统，其包括可从闭合位置移动到打开位置的组织移位或铰接扩张构件。可以提供致动组件用于在打开和关闭位置之间移动组织膨胀构件，以在围绕封闭血管的区域上施加基本上横向的远端力。组织膨胀构件可以充分拉伸分开，撕裂或以其它方式破坏血管闭塞，以产生可以支撑导线或介入血管装置穿过闭塞或阻塞的通道或放置的路径。还提供了交叉或移位血管闭塞的方法，其包括定位血管导管，所述血管导管具有定位在导管的远端区域处的至少一个铰接扩张构件，其响应于沿着导管的纵向轴线的定向力。定向力被施加到致动器以便展开铺展构件并且移位血管闭塞，产生路径以允许导线或器件通过其中。

7. 发明授权

US06508825B1 Apparatus for treating vascular occlusions 有权
标题翻译：用于治疗血管闭塞的装置
公开(公告)号：US06508825B1
公开(公告)日：2003-01-21
申请号：US09149874
申请日：1998-09-08
申请人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl , Gerald Hansen , E. Richard Hill, III
发明人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl , Gerald Hansen , E. Richard Hill, III
IPC分类号： A61M2900
CPC分类号： A61M29/02 , A61B17/22 , A61B17/22031 , A61B2017/00845 , A61B2017/22052 , A61B2017/22069 , A61B2017/22094 , A61B2017/2933 , A61B2017/2937 , A61B2017/320044 , A61B2017/320741
摘要： An intravascular catheter system for the treatment of occluded blood vessels that includes tissue displacement or hinged expansion members that are movable from a closed to an open position. An actuating assembly may be, provided for moving the tissue expansion members between an open and closed position to exert a substantially lateral distal end force upon the region surrounding an occluded blood vessel. The tissue expansion members may stretch apart, tear or otherwise disrupt a vascular occlusion sufficiently to create a pathway that may support the passage or placement of a guidewire or an interventional vascular device across the occlusion or obstruction. Methods of crossing or displacing a vascular occlusion are further provided that include the positioning of a vascular catheter having at least one hinged spreading member positioned at the distal region of the catheter that is responsive to directed force along the longitudinal axis of the catheter. A directed force is applied to the actuator in order to deploy the spreading member and displace a vascular occlusion creating a path to permit the passage of a guidewire or device therethrough.
摘要翻译：一种用于治疗闭塞血管的血管内导管系统，其包括可从闭合位置移动到打开位置的组织移位或铰接扩张构件。可以提供致动组件，用于在打开和关闭位置之间移动组织膨胀构件，以在围绕封闭血管的区域上施加基本上横向的远端力。组织膨胀构件可以充分拉伸分开，撕裂或以其它方式破坏血管闭塞，以产生可以支撑导线或介入血管装置穿过闭塞或阻塞的通道或放置的路径。还提供了交叉或移位血管闭塞的方法，其包括定位血管导管，所述血管导管具有定位在导管的远端区域处的至少一个铰接扩张构件，其响应于沿着导管的纵向轴线的定向力。定向力被施加到致动器以便展开铺展构件并且移位血管闭塞，产生路径以允许导线或器件通过其中。

8. 发明授权

US07004173B2 Catheter system for vascular re-entry from a sub-intimal space 失效
公开(公告)号：US07004173B2
公开(公告)日：2006-02-28
申请号：US10010410
申请日：2001-12-05
申请人： Kurt D. Sparks , Jeffrey L. Emery , Brent D. Seybold , David J. Kupiecki , C. Danielle Pinson , Allen W. Madsen , Michael D. Keleher , Sergio Salinas , Benjamin J. Clark , Matthew R. Selmon
发明人： Kurt D. Sparks , Jeffrey L. Emery , Brent D. Seybold , David J. Kupiecki , C. Danielle Pinson , Allen W. Madsen , Michael D. Keleher , Sergio Salinas , Benjamin J. Clark , Matthew R. Selmon
IPC分类号： A61B19/00
CPC分类号： A61B17/320783 , A61B17/3207 , A61B90/37 , A61B2017/00252 , A61B2017/22077 , A61B2017/22094 , A61B2017/22095 , A61B2090/378 , A61B2090/3782
摘要： A catheter system and corresponding methods are provided for accessing a blood vessel true lumen from a sub-intimal plane of the vessel. The catheter system includes visualization elements for determining the orientation of the true lumen with respect to the sub-intimal plane at an identified entry site from a position in the sub-intimal plane. The entry site is distal to a chronic total occlusion (CTO). The catheter system also includes a system for physically securing tissue of the sub-intimal plane at the entry site to the catheter system. The attaching system reduces or eliminates catheter float within the sub-intimal space. The catheter system further includes re-entry devices to establish and maintain a path from the sub-intimal plane back into the vessel true lumen.

9. 发明授权

US06217549B1 Methods and apparatus for treating vascular occlusions 有权
标题翻译：治疗血管闭塞的方法和装置
公开(公告)号：US06217549B1
公开(公告)日：2001-04-17
申请号：US09149875
申请日：1998-09-08
申请人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl
发明人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl
IPC分类号： A61M2900
CPC分类号： A61M29/02 , A61B17/22 , A61B17/22031 , A61B2017/00845 , A61B2017/22069 , A61B2017/2933 , A61B2017/2937 , A61B2017/320044 , A61B2017/320741
摘要： An intravascular catheter system for the treatment of occluded blood vessels that includes tissue displacement or hinged expansion members that are movable from a closed to an open position. An actuating assembly may be provided for moving the tissue expansion members between an open and closed position to exert a substantially lateral distal end force upon the region surrounding an occluded blood vessel. The tissue expansion members may stretch apart, tear or otherwise disrupt a vascular occlusion sufficiently to create a pathway that may support the passage or placement of a guidewire or an interventional vascular device across the occlusion or obstruction. Methods of crossing or displacing a vascular occlusion are further provided that include the positioning of a vascular catheter having at least one hinged spreading member positioned at the distal region of the catheter that is responsive to directed force along the longitudinal axis of the catheter. A directed force is applied to the actuator in order to deploy the spreading member and displace a vascular occlusion creating a path to permit the passage of a guidewire or device therethrough.
摘要翻译：一种用于治疗闭塞血管的血管内导管系统，其包括可从闭合位置移动到打开位置的组织移位或铰接扩张构件。可以提供致动组件用于在打开和关闭位置之间移动组织膨胀构件，以在围绕封闭血管的区域上施加基本上横向的远端力。组织膨胀构件可以充分拉伸分开，撕裂或以其它方式破坏血管闭塞，以产生可以支撑导线或介入血管装置穿过闭塞或阻塞的通道或放置的路径。还提供了交叉或移位血管闭塞的方法，其包括定位血管导管，所述血管导管具有定位在导管的远端区域处的至少一个铰接扩张构件，其响应于沿着导管的纵向轴线的定向力。定向力被施加到致动器以便展开铺展构件并且移位血管闭塞，产生路径以允许导线或器件通过其中。

10. 发明授权

US06266550B1 Catheter apparatus for treating arterial occlusions 有权
标题翻译：用于治疗动脉闭塞的导管器械
公开(公告)号：US06266550B1
公开(公告)日：2001-07-24
申请号：US09483173
申请日：2000-01-13
申请人： Matthew R. Selmon , James W. Vetter , Tomoaki Hinohara , Charles F. Milo
发明人： Matthew R. Selmon , James W. Vetter , Tomoaki Hinohara , Charles F. Milo
IPC分类号： A61B1732
CPC分类号： A61B17/3207 , A61B8/12 , A61B17/320725 , A61B17/320758 , A61B2017/22077 , A61B2017/308 , A61B2017/320004 , A61B2017/320044 , A61B2090/3784 , A61M25/0147
摘要： An apparatus is described for treating arterial occlusions combining an intraluminally operable catheter, having an occlusion-crossing working element, with a micro-invasive extraluminally operable locator for imaging the progress of the working element through the occlusion. Conical, abrasive, blunt-dissecting, and sharp-pointed, and steering and non-steering working elements including guide wires are described. Acoustic transducers and a flexible imaging tube are described for the locator. A suction cup is described for removably anchoring the imaging tube to a surface. A signal-emitting working element and cooperating signal-receiving locator are described. A method for treating arterial occlusions is described.
摘要翻译：描述了一种用于治疗动脉闭塞的装置，其组合具有阻塞交叉工作元件的可透光操作的导管与微创外向可操作的定位器，用于通过闭塞成像工作元件的进展。描述了包括导丝在内的锥形，磨料，钝性解剖和锋利的转向和非转向工作元件。描述了定位器的声学换能器和柔性成像管。描述了用于可移除地将成像管固定到表面的吸盘。描述信号发射工作元件和配合信号接收定位器。描述了治疗动脉闭塞的方法。

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