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1. 发明授权

US5919161A Guidewire migration controller 失效
标题翻译：导丝迁移控制器
公开(公告)号：US5919161A
公开(公告)日：1999-07-06
申请号：US531145
申请日：1995-09-18
申请人： E. Richard Hill, III , Glenn Davis , Brian Farley
发明人： E. Richard Hill, III , Glenn Davis , Brian Farley
IPC分类号： A61B17/22 , A61M37/00
CPC分类号： A61M25/09041 , A61B2017/22038
摘要： Disclosed herein is a guidewire migration controller for use with catheter devices such as atherectomy catheters. The guidewire migration controller includes a housing, a gripper insertable in the housing and a locking member. The locking member holds the gripper within the housing. The gripper has an opening for receiving a guidewire. The gripper permits the guidewire to rotate and holds the guidewire to control guidewire migration.
摘要翻译：本文公开了一种用于导管装置例如粥样斑块切除术导管的导丝迁移控制器。导丝移动控制器包括壳体，可插入壳体中的夹具和锁定构件。锁定构件将夹持器保持在壳体内。夹具具有用于接收导丝的开口。夹具允许导丝线旋转并保持导丝以控制导丝移动。

2. 发明授权

US06746446B1 Electrophysiological device for the isthmus 失效
标题翻译：峡谷电生理装置
公开(公告)号：US06746446B1
公开(公告)日：2004-06-08
申请号：US09633054
申请日：2000-08-04
申请人： E. Richard Hill, III , Sung Chun , Reynaldo P. Hilario , Tim Ngeo Huynh , Mahmoud R. Seraj , Robert Obara
发明人： E. Richard Hill, III , Sung Chun , Reynaldo P. Hilario , Tim Ngeo Huynh , Mahmoud R. Seraj , Robert Obara
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2017/00867 , A61B2018/00029 , A61B2018/00351 , A61B2018/00797 , A61B2018/00821 , A61B2018/00839 , A61B2018/1467 , C08L2201/12
摘要： An intravascular electrophysiology (EP) device for the mapping and/or formation of lesions along the isthmus region of a heart that has particular utility in the treatment of atrial flutter. The EP device of the invention has an elongated shaft with a proximal section, a compound-curved or modified pigtail-shaped distal section, and a plurality of at least partially exposed electrodes disposed on an outer surface of the distal section. The electrodes are spaced along a length of the distal section and may be interspersed with at least one temperature sensor located between electrodes. The shape of the distal end of the device enables manipulation of the device by inserting its distal end in the tricuspid valve and retracting the device to bias the section having electrodes along the isthmus to achieve acceptable contact with the region so high frequency (e.g., RF) electrical energy delivered to the electrodes on the distal section of the EP device will form a lesion. Sections of the isthmus where treatment is desired but not reached by the section of the device biased against tissue by retraction may be ablated by repeating the steps of hooking the tricuspid valve at a different end location of the device and retracting to bias the electrodes against different tissue, simply advancing the section with electrodes to the desired site or retracting the device so a tip connected to an RF source will drop into a desired site where ablation may occur.
摘要翻译：用于沿着心脏的峡部区域映射和/或形成病变的血管内电生理学（EP）装置，其特别用于治疗心房扑动。本发明的EP装置具有细长轴，其具有近端部分，复合弯曲或修改的尾纤形远端部分，以及设置在远侧部分的外表面上的多个至少部分暴露的电极。电极沿着远端部分的长度间隔开，并且可以散布在位于电极之间的至少一个温度传感器。该装置的远端的形状使得能够通过将其远端插入三尖瓣并且缩回装置来偏转具有沿着峡部的电极的部分来实现装置的操作，以实现与该区域的可接受的接触，从而高频（例如，RF ）传送到EP装置的远端部分上的电极的电能将形成病变。可以通过重复将三尖瓣钩挂在装置的不同端部位置的步骤来消除通过缩回偏压组织的装置的部分而不能达到处理的部位，并且缩回以将电极偏压到不同的位置组织，简单地将具有电极的部分推进到所需位置或缩回装置，使得连接到RF源的尖端将落入可能发生消融的期望位置。

3. 发明授权

US06638247B1 Method and apparatus for treating vascular occlusions 有权
标题翻译：治疗血管闭塞的方法和装置
公开(公告)号：US06638247B1
公开(公告)日：2003-10-28
申请号：US09538441
申请日：2000-03-29
申请人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl , Gerald Hansen , E. Richard Hill, III
发明人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl , Gerald Hansen , E. Richard Hill, III
IPC分类号： A61M2900
CPC分类号： A61M29/02 , A61B17/22 , A61B17/22031 , A61B2017/00845 , A61B2017/22052 , A61B2017/22069 , A61B2017/22094 , A61B2017/2933 , A61B2017/2937 , A61B2017/320044 , A61B2017/320741
摘要： An intravascular catheter system for the treatment of occluded blood vessels that includes tissue displacement or hinged expansion members that are movable from a closed to an open position. An actuating assembly may be provided for moving the tissue expansion members between an open and closed position to exert a substantially lateral distal end force upon the region surrounding an occluded blood vessel. The tissue expansion members may stretch apart, tear or otherwise disrupt a vascular occlusion sufficiently to create a pathway that may support the passage or placement of a guidewire or an interventional vascular device across the occlusion or obstruction. Methods of crossing or displacing a vascular occlusion are further provided that include the positioning of a vascular catheter having at least one hinged spreading member positioned at the distal region of the catheter that is responsive to directed force along the longitudinal axis of the catheter. A directed force is applied to the actuator in order to deploy the spreading member and displace a vascular occlusion creating a path to permit the passage of a guidewire or device therethrough.
摘要翻译：一种用于治疗闭塞血管的血管内导管系统，其包括可从闭合位置移动到打开位置的组织移位或铰接扩张构件。可以提供致动组件用于在打开和关闭位置之间移动组织膨胀构件，以在围绕封闭血管的区域上施加基本上横向的远端力。组织膨胀构件可以充分拉伸分开，撕裂或以其它方式破坏血管闭塞，以产生可以支撑导线或介入血管装置穿过闭塞或阻塞的通道或放置的路径。还提供了交叉或移位血管闭塞的方法，其包括定位血管导管，所述血管导管具有定位在导管的远端区域处的至少一个铰接扩张构件，其响应于沿着导管的纵向轴线的定向力。定向力被施加到致动器以便展开铺展构件并且移位血管闭塞，产生路径以允许导线或器件通过其中。

4. 发明授权

US06508825B1 Apparatus for treating vascular occlusions 有权
标题翻译：用于治疗血管闭塞的装置
公开(公告)号：US06508825B1
公开(公告)日：2003-01-21
申请号：US09149874
申请日：1998-09-08
申请人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl , Gerald Hansen , E. Richard Hill, III
发明人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl , Gerald Hansen , E. Richard Hill, III
IPC分类号： A61M2900
CPC分类号： A61M29/02 , A61B17/22 , A61B17/22031 , A61B2017/00845 , A61B2017/22052 , A61B2017/22069 , A61B2017/22094 , A61B2017/2933 , A61B2017/2937 , A61B2017/320044 , A61B2017/320741
摘要： An intravascular catheter system for the treatment of occluded blood vessels that includes tissue displacement or hinged expansion members that are movable from a closed to an open position. An actuating assembly may be, provided for moving the tissue expansion members between an open and closed position to exert a substantially lateral distal end force upon the region surrounding an occluded blood vessel. The tissue expansion members may stretch apart, tear or otherwise disrupt a vascular occlusion sufficiently to create a pathway that may support the passage or placement of a guidewire or an interventional vascular device across the occlusion or obstruction. Methods of crossing or displacing a vascular occlusion are further provided that include the positioning of a vascular catheter having at least one hinged spreading member positioned at the distal region of the catheter that is responsive to directed force along the longitudinal axis of the catheter. A directed force is applied to the actuator in order to deploy the spreading member and displace a vascular occlusion creating a path to permit the passage of a guidewire or device therethrough.
摘要翻译：一种用于治疗闭塞血管的血管内导管系统，其包括可从闭合位置移动到打开位置的组织移位或铰接扩张构件。可以提供致动组件，用于在打开和关闭位置之间移动组织膨胀构件，以在围绕封闭血管的区域上施加基本上横向的远端力。组织膨胀构件可以充分拉伸分开，撕裂或以其它方式破坏血管闭塞，以产生可以支撑导线或介入血管装置穿过闭塞或阻塞的通道或放置的路径。还提供了交叉或移位血管闭塞的方法，其包括定位血管导管，所述血管导管具有定位在导管的远端区域处的至少一个铰接扩张构件，其响应于沿着导管的纵向轴线的定向力。定向力被施加到致动器以便展开铺展构件并且移位血管闭塞，产生路径以允许导线或器件通过其中。

5. 发明授权

US5741270A Manual actuator for a catheter system for treating a vascular occlusion 失效
标题翻译：用于治疗血管闭塞的导管系统的手动致动器
公开(公告)号：US5741270A
公开(公告)日：1998-04-21
申请号：US808092
申请日：1997-02-28
申请人： Gerald Hansen , E. Richard Hill, III , Charles Milo
发明人： Gerald Hansen , E. Richard Hill, III , Charles Milo
IPC分类号： A61B17/00 , A61B17/22 , A61B17/28 , A61F11/00
CPC分类号： A61B17/2909 , A61B17/32075 , A61B2017/00469 , A61B2017/2918
摘要： Disclosed herein is manual actuator for retracting and advancing a therapeutic working element of an intravascular catheter system via an actuation shaft or one or more pulling wires. The manual actuator includes a hollow cylindrical bracing member having an open proximal end and a distal end, and a hollow cylindrical retracting member, the retracting member being slidable, in a telescoping fashion, into the open proximal end of the bracing member. An actuation shaft is secured near to the proximal end of the retracting member and the distal end of the actuation shaft is secured to the therapeutic working element. Alternatively, at least one pulling wire is secured proximal to the proximal end of the retracting member. The distal end of the pulling wire is secured to the therapeutic working element. At least one resilient connecting member has a proximal end attached proximate the proximal end of the retracting member, and a distal end attached proximate the distal end of the bracing member. When a manually applied external force is applied by the physician to the resilient connecting members, the resilient connecting members urge the retracting member in a proximal direction with respect to the bracing member, and retracting the actuation shaft to thereby operate the working element of the catheter system. Alternatively, the retracting member is urged in the proximal direction by the manually applied external force and the pulling wires transmit this force to the therapeutic working element.
摘要翻译：这里公开了用于通过致动轴或一个或多个牵引线回缩和推进血管内导管系统的治疗工作元件的手动致动器。手动致动器包括具有开口近端和远端的中空圆柱形支撑构件和中空圆柱形缩回构件，缩回构件可以伸缩方式滑动到支撑构件的开放近端中。致动轴固定在靠近收缩构件的近端并且致动轴的远端固定到治疗工作元件。或者，至少一个拉线被固定在靠近收缩构件的近端的位置。拉线的远端固定在治疗工作元件上。至少一个弹性连接构件具有靠近缩回构件的近端附近的近端，以及靠近支撑构件的远端附近的远端。当医师将手动施加的外力施加到弹性连接构件时，弹性连接构件相对于支撑构件在近端方向上推动缩回构件，并且使致动轴缩回从而操作导管的工作元件系统。或者，缩回构件通过手动施加的外力在近端方向被推压，并且牵引线将该力传递到治疗工作元件。

6. 发明授权

US06800085B2 Methods and apparatus for treating vascular occlusions 有权
公开(公告)号：US06800085B2
公开(公告)日：2004-10-05
申请号：US09835043
申请日：2001-04-13
申请人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl , Gerald Hansen , E. Richard Hill, III
发明人： Matthew R. Selmon , Charles F. Milo , Robert L. Wynne , Suresh S. Pai , Kent D. Dell , Charles Gresl , Gerald Hansen , E. Richard Hill, III
IPC分类号： A61M2900
CPC分类号： A61M29/02 , A61B17/22 , A61B17/22031 , A61B2017/00845 , A61B2017/22052 , A61B2017/22069 , A61B2017/22094 , A61B2017/2933 , A61B2017/2937 , A61B2017/320044 , A61B2017/320741
摘要： An intravascular catheter system for the treatment of occluded blood vessels that includes tissue displacement or hinged expansion members that are movable from a closed to an open position. An actuating assembly may be provided for moving the tissue expansion members between an open and closed position to exert a substantially lateral distal end force upon the region surrounding an occluded blood vessel. The tissue expansion members may stretch apart, tear or otherwise disrupt a vascular occlusion sufficiently to create a pathway that may support the passage or placement of a guidewire or an interventional vascular device across the occlusion or obstruction. Methods of crossing or displacing a vascular occlusion are further provided that include the positioning of a vascular catheter having at least one hinged spreading member positioned at the distal region of the catheter that is responsive to directed force along the longitudinal axis of the catheter. A directed force is applied to the actuator in order to deploy the spreading member and displace a vascular occlusion creating a path to permit the passage of a guidewire or device therethrough.

7. 发明授权

US5499632A Guide wire migration controller 失效
标题翻译：导丝移动控制器
公开(公告)号：US5499632A
公开(公告)日：1996-03-19
申请号：US237690
申请日：1994-05-04
申请人： E. Richard Hill, III , Glenn Davis , Brian Farley
发明人： E. Richard Hill, III , Glenn Davis , Brian Farley
IPC分类号： A61B17/22 , A61M37/00
CPC分类号： A61M25/09041 , A61B2017/22038
摘要： Disclosed herein is a guide wire migration controller device. The device includes a housing, a gripper insertable in the housing and a locking member for keeping the gripper within the housing. The gripper grips a guide wire operated by a motor drive unit. The gripper limits the migrational movement of the guide wire by gripping the guide wire and limiting the movement to the amount of tolerance between the gripper and the housing and locking member. The gripper rotates freely within the housing depending upon the rotational movement of the catheter torque cable wire. In a preferred embodiment the migrational movement of the guide wire along its longitudinal axis is translated into slidable movement of the controller relative to the motor drive unit.
摘要翻译：这里公开了导丝移动控制器装置。该装置包括壳体，可插入壳体中的夹具和用于将夹持器保持在壳体内的锁定构件。夹具夹住由电机驱动单元操作的导丝。夹持器通过夹持导丝来限制导丝的移动运动，并将移动限制在夹持器与壳体和锁定构件之间的公差的量。取决于导管扭矩电缆线的旋转运动，夹具在壳体内自由旋转。在优选实施例中，导丝沿其纵向轴线的移动运动被转换成控制器相对于马达驱动单元的滑动运动。

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