专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20060093675A1 Intravaginal treatment of vaginal infections with metronidazole compositions 审中-公开
标题翻译：用甲硝唑组合物对阴道感染进行阴道内治疗
公开(公告)号：US20060093675A1
公开(公告)日：2006-05-04
申请号：US10978235
申请日：2004-10-29
申请人： Mathew Ebmeier , Robert Lathrop
发明人： Mathew Ebmeier , Robert Lathrop
IPC分类号： A61K9/14 , A61K31/4164
CPC分类号： A61K9/0034 , A61K31/4164
摘要： The present invention provides a buffered non-flowing composition suitable for the treatment of bacterial vaginosis. The composition includes metronidazole in a concentration of about 0.50% (w/w) to about 1.50% (w/w). The metronidazole is present together with a buffer system in a physiologically tolerable medium. The buffer system provides an acidic buffered pH value for the composition in the range of about 5.0 to about 6.0. The present invention also provides for a method for inhibiting a microorganism. The method includes contacting a microorganism with an effective amount of the composition of the present invention, for a period of time effective to inhibit the microorganism. The present invention also provides for a method for treating bacterial vaginosis in a human patient. The method includes intravaginal administration to a patient in need of such treatment an effective amount of the composition the present invention. The composition is introduced into the vagina at least once a day for a time period of at least one day.
摘要翻译：本发明提供了适用于治疗细菌性阴道病的缓冲非流动组合物。组合物包含浓度为约0.50％（w / w）至约1.50％（w / w）的甲硝唑。甲硝唑与缓冲系统一起存在于生理上可耐受的培养基中。缓冲系统为组合物提供约5.0至约6.0范围内的酸性缓冲pH值。本发明还提供了抑制微生物的方法。该方法包括使微生物与有效量的本发明组合物接触一段有效抑制微生物的时间。本发明还提供了一种在人类患者中治疗细菌性阴道病的方法。该方法包括对需要这种治疗的患者的阴道内施用有效量的本发明的组合物。每天至少一次将组合物引入阴道至少一天的时间。

2. 发明申请

US20060078599A1 Pharmaceutical composition applicable to body tissue 审中-公开
标题翻译：适用于身体组织的药物组合物
公开(公告)号：US20060078599A1
公开(公告)日：2006-04-13
申请号：US10962989
申请日：2004-10-12
申请人： Mathew Ebmeier , Robert Lathrop
发明人： Mathew Ebmeier , Robert Lathrop
IPC分类号： A61K36/14 , A61K31/717 , A61K31/137 , A61K31/045 , A61K31/125
CPC分类号： A61K9/7015 , A61K9/0014 , A61K31/045 , A61K31/125 , A61K31/137 , A61K31/496 , A61K31/717 , A61K47/08 , A61K47/10 , A61K47/38
摘要： The present invention provides a non-water soluble, film-forming composition which adheres to body tissue and forms a pharmaceutical carrier to provide localized delivery of an antifungal agent to a treatment site. The composition will typically include: (a) an alkyl cellulose; (b) a hydroxyalkyl cellulose; (c) a pharmaceutically acceptable polar protic solvent; (d) an antifungal agent selected from the group of naftifine, ciclopirox, terbinafine, pharmaceutically acceptable salts thereof, and combinations thereof; (e) an glycol ether; (f) an antipruritic agent selected from the group of camphor, menthol, butamben picrate, metacresol, benzyl alcohol, camphorated metacresol, juniper tar, phenol, phenolate sodium, resorcinol, camphorated metacresol, carbolic acid, and combinations,; and (g) a solubility enhancing agent, a surfactant, a wetting agent, or a combination thereof. The present invention also provides for the use of the composition composition of the present invention, in treating a fungal infection (e.g., nail fungus) in a mammal afflicted with such an infection.
摘要翻译：本发明提供了一种非水溶性成膜组合物，其粘附于身体组织并形成药物载体以提供抗真菌剂向治疗部位的局部递送。组合物通常包括：（a）烷基纤维素; （b）羟烷基纤维素; （c）药学上可接受的极性质子溶剂; （d）选自脱头芬，环吡酮，特比萘芬，其药学上可接受的盐及其组合的抗真菌剂; （e）乙二醇醚; （f）选自樟脑，薄荷醇，苦丁酸苦参酸，甲酚，苯甲醇，樟脑甲醇，杜松子焦油，苯酚，苯酚钠，间苯二酚，樟脑甲酚，卡拉酸及其组合的止痒剂。和（g）溶解度增强剂，表面活性剂，润湿剂或其组合。本发明还提供本发明的组合物组合物在治疗患有这种感染的哺乳动物中的真菌感染（例如指甲真菌）中的用途。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式