专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5241064A Enzymatic process for preparing optically active 3-substituted azetidinones 失效
标题翻译：用于制备光学活性3-取代的AZETIDINONES的酶法
公开(公告)号：US5241064A
公开(公告)日：1993-08-31
申请号：US587037
申请日：1990-09-24
申请人： Masayoshi Murata , Toshiyuki Chiba , Fumiyuki Shirai , Kenichi Washizuka , Motohiro Hino
发明人： Masayoshi Murata , Toshiyuki Chiba , Fumiyuki Shirai , Kenichi Washizuka , Motohiro Hino
IPC分类号： C07B53/00 , C07D205/08 , C12P7/42 , C12P41/00
CPC分类号： C12R1/07 , C07D205/08 , C12P41/004 , C12P7/42 , Y02P20/55
摘要： Preparation of optically active 3-substituted azetidinones of the formula (I) ##STR1## in which R.sup.1 is a hydroxy-protective group wherein an allylic alcohol of the formula (II) ##STR2## is acylated, then subjected to asymmetric enzymatic hydrolysis yielding the R-allylic alcohol. The hydroxyl group is protected and then stereoselectively reacted with an amine which is subsequently cyclized to yield the desired 3-substituted azetidinone. Two new species of microorganisms have been isolated, Pimelobacter sp. No. 1254 and Bacillus megaterium No. 1253 which exhibit stereoselective esterase activity.

2. 发明授权

US5286721A 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds 失效
标题翻译： 1-氮杂双环[3.2.0]庚-2-烯-2-羧酸化合物
公开(公告)号：US5286721A
公开(公告)日：1994-02-15
申请号：US853746
申请日：1992-06-12
申请人： Masayoshi Murata , Toshiyuki Chiba , Hideo Tsutsumi , Kohji Hattori , Satoru Kuroda , Hiroaki Ohtake , Fumiyuki Shirai
发明人： Masayoshi Murata , Toshiyuki Chiba , Hideo Tsutsumi , Kohji Hattori , Satoru Kuroda , Hiroaki Ohtake , Fumiyuki Shirai
IPC分类号： C07D477/14 , C07D477/00
CPC分类号： C07D477/14
摘要： 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds of the formula: ##STR1## in which R.sup.1 is carboxy, COO.sup.-- or protected carboxy,R.sup.2 is hydroxy(lower)alkyl or protected hydroxy(lower)alkyl,R.sup.8 is hydrogen or lower alkyl,Z is a group of the formula: ##STR2## wherein R.sup.3 is hydrogen; lower alkyl or lower alkenyl, each of which is optionally substituted by the group consisting of lower alkoxy, carbamoyl, hydroxy, halogen, mono(or di)(lower)alkylcarbamoyl, mono(or di)(lower)alkenylcarbamoyl, mono(or bis)[hydroxy(lower)alkyl]carbamoyl, optionally substituted cyclic-aminocarbonyl, acylamino, ureido, optionally substituted heterocyclic-carbonylamino, carbamoyloxy, mono(or di)(lower)alkylcarbamoyloxy, lower alkylthio, halo(lower)alkylthio, optionally substituted heterocyclicthio, optionally substituted heterocyclic group, optionally substituted aryl, and acyl;R.sup.9 is hydrogen or lower alkyl, andR.sup.10 is lower alkyl,or pharmaceutically acceptable salts thereof, which is useful as an antimicrobial agent.
摘要翻译： PCT No.PCT / JP91 / 01394 Sec。 371日期：1992年6月12日 102（e）日期1992年6月12日PCT 1991年10月14日PCT PCT。出版物WO92 / 06978 日期：4月30日，1992.1-氮杂双环（3.2.0）庚-2-烯-2-羧酸化合物，其结构式如下：（*化学结构*）其中R 1为羧基，COO-或被保护的羧基，R 2为羟基（低级）烷基或被保护的羟基（低级）烷基，R 8是氢或低级烷基，Z是下列基团：（*化学结构*）其中R 3是氢; 羟基，卤素，单（或二）（低级）烷基氨基甲酰基，单（或二）（低级）烯基氨基甲酰基，单（或双（低级））链烯基氨基甲酰基，）（羟基（低级）烷基）氨基甲酰基，任选取代的环氨基羰基，酰氨基，脲基，任选取代的杂环羰基氨基，氨基甲酰氧基，单（或二）（低级）烷基氨基甲酰氧基，低级烷硫基，卤（低级）烷硫基，，任选取代的杂环基，任选取代的芳基和酰基; R9为氢或低级烷基，R10为低级烷基，或其药学上可接受的盐，可用作抗微生物剂。

3. 发明授权

US5102877A 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds 失效
标题翻译： 1-氨基胆碱（3.2.0）HEPT-2-环己-2-羧酸化合物
公开(公告)号：US5102877A
公开(公告)日：1992-04-07
申请号：US508167
申请日：1990-04-12
申请人： Masayoshi Murata , Toshiyuki Chiba , Hideo Tsutsumi , Kohji Hattori , Satoru Kuroda , Hiroaki Ohtake , Fumiyuki Shirai
发明人： Masayoshi Murata , Toshiyuki Chiba , Hideo Tsutsumi , Kohji Hattori , Satoru Kuroda , Hiroaki Ohtake , Fumiyuki Shirai
IPC分类号： C07D477/00 , A61K31/397 , A61K31/40 , A61P31/04 , C07D477/14 , C07D519/00 , C07F7/18
CPC分类号： C07D477/14 , C07F7/186 , Y02P20/55
摘要： 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxyic acids having antimicrobial activity have been prepared.

4. 发明授权

US06826033B2 Aminoalcohol derivatives 失效
标题翻译：氨基醇衍生物
公开(公告)号：US06826033B2
公开(公告)日：2004-11-30
申请号：US10380627
申请日：2003-03-21
申请人： Minoru Sakurai , Kenichi Washizuka , Hitoshi Hamashima , Yasuyo Tomishima , Masashi Imanishi , Yutaka Nakajima , Hiroaki Ohtake , Satoru Kuroda , Masayoshi Murata , Hiroshi Kayakiri , Naoaki Fujii , Kiyoshi Taniguchi
发明人： Minoru Sakurai , Kenichi Washizuka , Hitoshi Hamashima , Yasuyo Tomishima , Masashi Imanishi , Yutaka Nakajima , Hiroaki Ohtake , Satoru Kuroda , Masayoshi Murata , Hiroshi Kayakiri , Naoaki Fujii , Kiyoshi Taniguchi
IPC分类号： H01G902
CPC分类号： C07D207/416 , C07C233/43 , C07C233/62 , C07C233/80 , C07C235/56 , C07C275/40 , C07C275/42 , C07C275/54 , C07C311/08 , C07C2601/10 , C07C2601/14 , C07C2602/10 , C07D207/34 , C07D209/08 , C07D209/18 , C07D209/40 , C07D209/42 , C07D209/88 , C07D213/40 , C07D213/56 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/38 , C07D215/40 , C07D215/48 , C07D215/50 , C07D217/22 , C07D217/26 , C07D231/14 , C07D231/56 , C07D233/90 , C07D235/06 , C07D235/08 , C07D235/16 , C07D237/28 , C07D241/20 , C07D241/42 , C07D241/44 , C07D249/08 , C07D261/14 , C07D261/18 , C07D261/20 , C07D263/34 , C07D277/28 , C07D277/56 , C07D295/215 , C07D307/54 , C07D307/66 , C07D307/68 , C07D307/82 , C07D333/36 , C07D333/38 , C07D333/66 , C07D333/70 , C07D487/04 , Y02P20/55
摘要： The present invention relates to a compound formula (I) wherein X1 is bond or —O—CH2—, (II) or (III) R1 is hydrogen or an amino protective group, a is phenyl, indolyl or carbazolyl, each of which may be substituted with one or two substituent(s), and B is hydrogen; halogen; lower alkyl; lower alkoxycarbonyl; cyclo(lower)alkyl; or a heterocyclic group, naphthyl, 1,2,3,4-tetrahydronaphthyl, benzyl or phenyl, each of which may be substituted with one or two substituent(s), or a salt thereof. The compound (I) of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiures or urinary incontinence.
摘要翻译：本发明涉及其中X 1为键或-O-CH 2 - ，（II）或（III）R 1为氢或氨基保护基的化合物式（I），a为苯基，吲哚基或咔唑基，各自为可以被一个或两个取代基取代，B是氢; 卤素; 低级烷基低级烷氧基羰基; 环（低级）烷基; 或杂环基，萘基，1,2,3,4-四氢萘基，苄基或苯基，其各自可以被一个或两个取代基取代，或其盐。本发明的化合物（I）及其药学上可接受的盐可用于预防和/或治疗感染或尿失禁。

5. 发明授权

US4923857A 3-Alkenyl-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid compounds 失效
标题翻译： 3-烯基-1-氮杂双环（3.2.0）庚-2-烯-2-羧酸化合物
公开(公告)号：US4923857A
公开(公告)日：1990-05-08
申请号：US312061
申请日：1989-02-17
申请人： Masayoshi Murata , Toshiyuki Chiba , Akira Yamada
发明人： Masayoshi Murata , Toshiyuki Chiba , Akira Yamada
IPC分类号： C07D477/00 , A61K31/397 , A61K31/40 , A61P31/04 , C07D477/14
CPC分类号： C07D477/14
摘要： The invention relates to an antimicrobial compound of the formula: ##STR1## in which R.sup.1 is carboxy or protected carboxy,R.sup.2 is hydroxy(lower)alkyl or protected hydroxy(lower)alkyl,R.sup.3 and R.sup.4 are each hydrogen or lower alkyl, andR.sup.5 is saturated 4 to 6-membered heteromonocyclic group containing 1 to 4 nitrogen atom(s), saturated 5 or 6-membered heteromonocyclic group containing 1 to 2 oxygen atom(s) and 1 to 3 nitrogen atom(s) or saturated 5 or 6-membered heteromonocyclic group containing 1 to 2 sulfur atom(s) and 1 to 3 nitrogen atom(s), wherein said aliphatic heterocyclic group may be substituted by one or more suitable substituent(s) selected from a group consisting of hydroxy, protected hydroxy, hydroxy(lower)alkyl, protected hydroxy(lower)alkyl, halogen, lower alkoxy, lower alkyl, lower alkoxy(lower)alkyl, imino, protected imino, lower alkylamino, protected lower alkylamino, mono(or di)-(lower)alkylcarbamoyloxy, lower alkylidene, lower alkanimidoyl and imino-protective group, or pharmaceutically acceptable salts thereof.

6. 发明授权

US5081237A 3-alkenyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds 失效
标题翻译： 3-氨基-1-氮杂双环（3.2.0）HEPT-2-环己基-2-羧酸化合物
公开(公告)号：US5081237A
公开(公告)日：1992-01-14
申请号：US472270
申请日：1990-01-30
申请人： Masayoshi Murata , Toshiyuki Chiba , Akira Yamada
发明人： Masayoshi Murata , Toshiyuki Chiba , Akira Yamada
IPC分类号： C07D477/00 , A61K31/397 , A61K31/40 , A61P31/04 , C07D477/14
CPC分类号： C07D477/14
摘要： The invention relates to novel intermediate compounds for preparation of compounds of high antimicrobial activity, said intermediate compounds being of one of the formulas: ##STR1## wherein R.sup.1 is carboxy or protected carboxy,R.sup.2 is hydroxy(lower)alkyl or protected hyroxy(lower)alkyl,R.sup.3 and R.sup.4 are each hydrogen or lower alkyl,R.sup.5 is a saturated heterocyclic group, andR.sup.6 is aryl or lower alkoxy,or pharmaceutically acceptable salts thereof.

7. 发明授权

US06344701B1 Pulse generator for treating exhaust gas 失效
标题翻译：用于处理废气的脉冲发生器
公开(公告)号：US06344701B1
公开(公告)日：2002-02-05
申请号：US09369842
申请日：1999-08-09
申请人： Keisuke Kawamura , Tetsuro Shigemizu , Hirohisa Yoshida , Masayoshi Murata
发明人： Keisuke Kawamura , Tetsuro Shigemizu , Hirohisa Yoshida , Masayoshi Murata
IPC分类号： H03K302
CPC分类号： F01N3/0892 , B01D53/32 , B01D2259/818 , B01J19/088 , B01J2219/0807 , B01J2219/0875 , B01J2219/0894
摘要： An apparatus and method for treating exhaust gases. In this apparatus, a plurality of stages of reactor chambers (R1, R2, . . . Rn) are connected in series in the direction of an exhaust gas flow. Further, high-voltage power supplies (V1, V2, . . . and Vn) are connected to the reactor chambers (R1, R2, . . . and Rn), respectively. Moreover, in each of these reactor chambers, a streamer discharger plasma is generated. Furthermore, the more downstream a reactor chamber of a stage is placed, the lower energy to be cast into the reactor chamber becomes. The density of electrons generated in a gas decomposition unit is high in a portion thereof on the upstream side of the exhaust gas flow and the electron density is low in a portion thereof on the downstream side. Additionally, the present invention further provides a pulse generator in which a high voltage, which is an output voltage of a D.C. charger (V0), is simultaneously applied to a plurality of distributed constant lines (or transmission lines) (1−1, 1−2, 2−1, 2−2, . . . , N−1 and N−2), which are connected in parallel with one another, by means of a signal shortcircuit switch (S1).
摘要翻译：一种处理废气的设备和方法。在这种装置中，多个反应室（R1，R2，...，Rn）在废气流的方向上串联连接。此外，高压电源（V1，V2，...和Vn）分别连接到电抗器室（R1，R2，...和Rn）。此外，在这些反应器室的每一个中，产生流光放电器等离子体。此外，放置阶段的反应室的下游越下游，要投入反应器室的较低能量变为。在气体分解单元中产生的电子的密度在排气流的上游侧的部分高，并且其下游侧的部分的电子密度低。另外，本发明还提供一种脉冲发生器，其中作为直流充电器（V0）的输出电压的高电压同时施加到多个分布常数线路（或传输线路）（1-1,1） -2,2-1,2-2，...，N-1和N-2），它们通过信号短路开关（S1）彼此并联连接。

8. 发明授权

US06307146B1 Amorphous silicon solar cell 失效
标题翻译：非晶硅太阳能电池
公开(公告)号：US06307146B1
公开(公告)日：2001-10-23
申请号：US09404409
申请日：1999-09-23
申请人： Yoshiaki Takeuchi , Masayoshi Murata , Akemi Takano , Tatsuyuki Nishimiya , Syouji Morita , Tatsufumi Aoi , Tatsuji Horioka
发明人： Yoshiaki Takeuchi , Masayoshi Murata , Akemi Takano , Tatsuyuki Nishimiya , Syouji Morita , Tatsufumi Aoi , Tatsuji Horioka
IPC分类号： H01L310376
CPC分类号： H01L31/028 , H01L31/03762 , H01L31/075 , H01L31/202 , Y02E10/547 , Y02E10/548 , Y02P70/521
摘要： An amorphous silicon solar cell includes a substrate, a transparent electrode formed on this substrate, a power-generating film formed on this transparent electrode, and a back-side electrode formed on this power-generating film. The power-generating film is formed by sequentially stacking p-type/i-type/n-type hydrogenated amorphous silicon layers. The defect density of the i-type hydrogenated amorphous silicon layer is less than 1015 defects/cc.
摘要翻译：非晶硅太阳能电池包括基板，形成在该基板上的透明电极，形成在该透明电极上的发电膜和形成在该发光膜上的背面电极。发电膜通过依次层叠p型/ i型/ n型氢化非晶硅层而形成。 i型氢化非晶硅层的缺陷密度小于1015缺陷/ cc。

9. 发明授权

US06207686B1 Endothelin antagonists 失效
标题翻译：内皮素拮抗剂
公开(公告)号：US06207686B1
公开(公告)日：2001-03-27
申请号：US08836198
申请日：1997-06-20
申请人： Masahiro Neya , Tatsuya Zenkoh , Hitoshi Sawada , Chiyoshi Kasahara , Masayoshi Murata , Keiji Hemmi
发明人： Masahiro Neya , Tatsuya Zenkoh , Hitoshi Sawada , Chiyoshi Kasahara , Masayoshi Murata , Keiji Hemmi
IPC分类号： A61K3138
CPC分类号： C07D405/12 , C07D209/20 , C07D317/60 , C07D409/12
摘要： A compound of formula (I), in which: R1 is lower alkyl, cyclo(lower)alkyl, optionally substituted aryl, optionally substituted heterocyclic group, cyclo(lower)alkyl(lower)alkyl, or ar(lower)alkyl; R2 is hydrogen, hydroxy or protected hydroxy; R3 is lower alkyl, aryl, ar(lower)alkyl or optionally substituted heterocyclic(lower)alkyl; R4 is carboxy, protected carboxy or lower alkylsufonylcarbamoyl; R5 is hydrogen or lower alkyl; R6 is hydrogen or heterocyclic group; A is a single bond or lower alkylene, and Ar is optionally substituted aryl, or pharmaceutically acceptable salts thereof, having endothelin antagonistic activity.
摘要翻译：式（I）化合物，其中：R 1为低级烷基，环（低级）烷基，任选取代的芳基，任选取代的杂环基，环（低级）烷基（低级）烷基或芳（低级）烷基; R2是氢，羟基或被保护的羟基; R3是低级烷基，芳基，芳（低级）烷基或任选取代的杂环（低级）烷基; R4是羧基，被保护的羧基或低级烷基磺酰基氨基甲酰基; R5是氢或低级烷基; R6是氢或杂环基; A是单键或低级亚烷基，Ar是具有内皮素拮抗活性的任选取代的芳基或其药学上可接受的盐。

10. 发明授权

US5261013A Photoelectric converter and image reading apparatus mounting the same 失效
标题翻译：安装光电转换器和图像读取装置
公开(公告)号：US5261013A
公开(公告)日：1993-11-09
申请号：US845052
申请日：1992-03-03
申请人： Masayoshi Murata , Katsumi Komiyama , Tatsundo Kawai , Makoto Ogura , Hiroo Ichihashi , Osamu Hamamoto
发明人： Masayoshi Murata , Katsumi Komiyama , Tatsundo Kawai , Makoto Ogura , Hiroo Ichihashi , Osamu Hamamoto
IPC分类号： H01L31/0216 , H04N1/028 , H04N1/031 , G06K9/00 , H01L31/02 , H04N1/024
CPC分类号： H04N1/02845 , H01L31/02164 , H04N1/02815 , H04N1/031
摘要： A photoelectric converter includes a transparent substrate having a photoelectric converting element provided on a surface opposing a document relating to reading of image information, a transparent support for supporting the substrate, and a light source provided on a surface of the support opposite to a supporting surface for the substrate. Light emitted from the light source is radiated on a document through the support and the substrate, and reflected light is received by the photoelectric converting element.
摘要翻译：光电转换器包括：透明基板，具有设置在与图像信息的读取有关的文件的表面上的光电转换元件，用于支撑基板的透明支撑体，以及设置在支撑体的与支撑面相对的表面上的光源用于基材。从光源发出的光通过支撑体和基板照射在文件上，反射光被光电转换元件接收。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式